Published in J Struct Funct Genomics on January 01, 2004
An expression vector tailored for large-scale, high-throughput purification of recombinant proteins. Protein Expr Purif (2006) 2.58
Staphylococcus aureus IsdG and IsdI, heme-degrading enzymes with structural similarity to monooxygenases. J Biol Chem (2004) 1.58
Large-scale evaluation of protein reductive methylation for improving protein crystallization. Nat Methods (2008) 1.55
High-throughput crystallography for structural genomics. Curr Opin Struct Biol (2009) 1.44
High-throughput protein purification and quality assessment for crystallization. Methods (2011) 1.44
Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint. BMC Bioinformatics (2007) 1.34
Structure of surface layer homology (SLH) domains from Bacillus anthracis surface array protein. J Biol Chem (2011) 1.12
Optimization of benzoxazole-based inhibitors of Cryptosporidium parvum inosine 5'-monophosphate dehydrogenase. J Med Chem (2013) 1.09
Crystal structures of delta1-pyrroline-5-carboxylate reductase from human pathogens Neisseria meningitides and Streptococcus pyogenes. J Mol Biol (2005) 1.08
Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis. Proc Natl Acad Sci U S A (2008) 1.06
Extracytoplasmic PAS-like domains are common in signal transduction proteins. J Bacteriol (2009) 1.05
NDM-1, the ultimate promiscuous enzyme: substrate recognition and catalytic mechanism. FASEB J (2013) 1.02
Characterization of a Bacillus subtilis transporter for petrobactin, an anthrax stealth siderophore. Proc Natl Acad Sci U S A (2009) 1.01
Structures of open (R) and close (T) states of prephenate dehydratase (PDT)--implication of allosteric regulation by L-phenylalanine. J Struct Biol (2007) 0.99
Crystal structure of aminopeptidase N from human pathogen Neisseria meningitidis. Proteins (2008) 0.99
Chapter 3. High-throughput protein purification for x-ray crystallography and NMR. Adv Protein Chem Struct Biol (2009) 0.97
Cleavable C-terminal His-tag vectors for structure determination. J Struct Funct Genomics (2010) 0.96
High-resolution structure of the nitrile reductase QueF combined with molecular simulations provide insight into enzyme mechanism. J Mol Biol (2010) 0.95
Biochemical and structural analysis of an Eis family aminoglycoside acetyltransferase from bacillus anthracis. Biochemistry (2015) 0.95
Approaches to automated protein crystal harvesting. Acta Crystallogr F Struct Biol Commun (2014) 0.93
To automate or not to automate: this is the question. J Struct Funct Genomics (2010) 0.93
Structural studies of ROK fructokinase YdhR from Bacillus subtilis: insights into substrate binding and fructose specificity. J Mol Biol (2010) 0.91
The 1.38 A crystal structure of DmsD protein from Salmonella typhimurium, a proofreading chaperone on the Tat pathway. Proteins (2008) 0.90
New LIC vectors for production of proteins from genes containing rare codons. J Struct Funct Genomics (2013) 0.89
The crystal structure of Aq_328 from the hyperthermophilic bacteria Aquifex aeolicus shows an ancestral histone fold. Proteins (2006) 0.89
Novel α-glucosidase from human gut microbiome: substrate specificities and their switch. FASEB J (2010) 0.87
Benefits of structural genomics for drug discovery research. Infect Disord Drug Targets (2009) 0.87
The optimization of in vitro high-throughput chemical lysis of Escherichia coli. Application to ACP domain of the polyketide synthase ppsC from Mycobacterium tuberculosis. J Struct Funct Genomics (2010) 0.87
The crystal structure of the effector-binding domain of the trehalose repressor TreR from Bacillus subtilis 168 reveals a unique quarternary assembly. Proteins (2007) 0.86
Insight into the sporulation phosphorelay: crystal structure of the sensor domain of Bacillus subtilis histidine kinase, KinD. Protein Sci (2013) 0.83
The mannitol operon repressor MtlR belongs to a new class of transcription regulators in bacteria. J Biol Chem (2009) 0.83
Functional and structural analysis of the siderophore synthetase AsbB through reconstitution of the petrobactin biosynthetic pathway from Bacillus anthracis. J Biol Chem (2012) 0.82
Characterization of transport proteins for aromatic compounds derived from lignin: benzoate derivative binding proteins. J Mol Biol (2012) 0.82
N. meningitidis 1681 is a member of the FinO family of RNA chaperones. RNA Biol (2010) 0.81
A complex lipoate utilization pathway in Listeria monocytogenes. J Biol Chem (2011) 0.80
Protein production for structural genomics using E. coli expression. Methods Mol Biol (2014) 0.80
Sensor domain of histidine kinase KinB of Pseudomonas: a helix-swapped dimer. J Biol Chem (2014) 0.78
GH1-family 6-P-β-glucosidases from human microbiome lactic acid bacteria. Acta Crystallogr D Biol Crystallogr (2013) 0.78
Structural and functional characterization of solute binding proteins for aromatic compounds derived from lignin: p-coumaric acid and related aromatic acids. Proteins (2013) 0.78
The crystal structures of the α-subunit of the α(2)β (2) tetrameric Glycyl-tRNA synthetase. J Struct Funct Genomics (2012) 0.78
Crystal structure of fatty acid/phospholipid synthesis protein PlsX from Enterococcus faecalis. J Struct Funct Genomics (2008) 0.78
Roles of intramolecular and intermolecular interactions in functional regulation of the Hsp70 J-protein co-chaperone Sis1. J Mol Biol (2015) 0.78
RsaM: a transcriptional regulator of Burkholderia spp. with novel fold. FEBS J (2014) 0.77
A novel transcriptional regulator of L-arabinose utilization in human gut bacteria. Nucleic Acids Res (2015) 0.77
Structural characterization and comparison of three acyl-carrier-protein synthases from pathogenic bacteria. Acta Crystallogr D Biol Crystallogr (2012) 0.77
Crystal structure of hypothetical protein YfiH from Shigella flexneri at 2 A resolution. Proteins (2006) 0.77
EsxB, a secreted protein from Bacillus anthracis forms two distinct helical bundles. Protein Sci (2015) 0.77
Hydrogen bond donation to the heme distal ligand of Staphylococcus aureus IsdG tunes the electronic structure. J Biol Inorg Chem (2015) 0.76
Structure of 2-oxo-3-deoxygalactonate kinase from Klebsiella pneumoniae. Acta Crystallogr D Biol Crystallogr (2011) 0.76
Crystal structures of the F and pSLT plasmid TraJ N-terminal regions reveal similar homodimeric PAS folds with functional interchangeability. Biochemistry (2014) 0.76
1.6 A crystal structure of YteR protein from Bacillus subtilis, a predicted lyase. Proteins (2005) 0.76
Salvage of failed protein targets by reductive alkylation. Methods Mol Biol (2014) 0.76
Analysis of periplasmic sensor domains from Anaeromyxobacter dehalogenans 2CP-C: structure of one sensor domain from a histidine kinase and another from a chemotaxis protein. Microbiologyopen (2013) 0.76
Crystal structure of an acetyltransferase protein from Vibrio cholerae strain N16961. Proteins (2007) 0.76
Expression screening of integral membrane proteins from Helicobacter pylori 26695. Protein Sci (2007) 0.76
Characterization of member of DUF1888 protein family, self-cleaving and self-assembling endopeptidase. J Biol Chem (2012) 0.75
New aminopeptidase from "microbial dark matter" archaeon. FASEB J (2015) 0.75
A microbial sensor for organophosphate hydrolysis exploiting an engineered specificity switch in a transcription factor. Nucleic Acids Res (2016) 0.75
Structure of YidB protein from Shigella flexneri shows a new fold with homeodomain motif. Proteins (2006) 0.75
A novel signal transduction protein: Combination of solute binding and tandem PAS-like sensor domains in one polypeptide chain. Protein Sci (2017) 0.75
Structure of SO2946 orphan from Shewanella oneidensis shows "jelly-roll" fold with carbohydrate-binding module. J Struct Funct Genomics (2008) 0.75
Crystal structure of SgcJ, an NTF2-like superfamily protein involved in biosynthesis of the nine-membered enediyne antitumor antibiotic C-1027. J Antibiot (Tokyo) (2016) 0.75
How Aromatic Compounds Block DNA Binding of HcaR Catabolite Regulator. J Biol Chem (2016) 0.75
Novel hexamerization motif is discovered in a conserved cytoplasmic protein from Salmonella typhimurium. J Struct Funct Genomics (2007) 0.75
The structure of pyogenecin immunity protein, a novel bacteriocin-like immunity protein from Streptococcus pyogenes. BMC Struct Biol (2009) 0.75
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A (2002) 6.00
Use of bacteriophage T7 lysozyme to improve an inducible T7 expression system. J Mol Biol (1991) 5.81
A new vector for high-throughput, ligation-independent cloning encoding a tobacco etch virus protease cleavage site. Protein Expr Purif (2002) 5.72
Rapid screening for improved solubility of small human proteins produced as fusion proteins in Escherichia coli. Protein Sci (2002) 2.51
Controlled intracellular processing of fusion proteins by TEV protease. Protein Expr Purif (2000) 2.38
Engineering soluble proteins for structural genomics. Nat Biotechnol (2002) 2.09
Shotgun crystallization strategy for structural genomics: an optimized two-tiered crystallization screen against the Thermotoga maritima proteome. Acta Crystallogr D Biol Crystallogr (2003) 1.92
Structural genomics: a pipeline for providing structures for the biologist. Protein Sci (2002) 1.91
Purification of proteins using polyhistidine affinity tags. Methods Enzymol (2000) 1.87
Structural proteomics: toward high-throughput structural biology as a tool in functional genomics. Acc Chem Res (2003) 1.62
Crystal structure of Enterococcus faecalis SlyA-like transcriptional factor. J Biol Chem (2003) 1.42
An integrated approach to structural genomics. Prog Biophys Mol Biol (2000) 1.33
A less laborious approach to the high-throughput production of recombinant proteins in Escherichia coli using 2-liter plastic bottles. Protein Expr Purif (2003) 1.32
Structural proteomics: prospects for high throughput sample preparation. Prog Biophys Mol Biol (2000) 1.28
Reduced background expression and improved plasmid stability with pET vectors in BL21 (DE3). Biotechniques (2000) 1.11
Structural genomics. Methods Biochem Anal (2003) 1.10
Streptococcus pneumonia YlxR at 1.35 A shows a putative new fold. Acta Crystallogr D Biol Crystallogr (2001) 1.07
Structure of Bacillus subtilis YXKO--a member of the UPF0031 family and a putative kinase. J Struct Biol (2002) 1.05
Crystal structure of Bacillus subtilis ioli shows endonuclase IV fold with altered Zn binding. Proteins (2002) 1.02
Autotracing of Escherichia coli acetate CoA-transferase alpha-subunit structure using 3.4 A MAD and 1.9 A native data. Acta Crystallogr D Biol Crystallogr (2002) 0.89
Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc Natl Acad Sci U S A (2008) 16.54
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature (2010) 12.07
The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study. Lancet (2008) 9.03
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science (2002) 7.87
A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus. Science (2006) 7.84
PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations. Nucleic Acids Res (2007) 7.07
Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J Exp Med (2009) 7.01
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. J Exp Med (2009) 4.79
Generation of induced pluripotent stem cell lines from adult rat cells. Cell Stem Cell (2008) 4.52
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1. Cell (2006) 4.13
Protein production and purification. Nat Methods (2008) 3.97
Second messenger-mediated adjustment of bacterial swimming velocity. Cell (2010) 3.69
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat Genet (2009) 3.59
Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA. Nature (2002) 3.45
Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis. Mol Carcinog (2010) 3.44
In vitro reconstitution of the human RISC-loading complex. Proc Natl Acad Sci U S A (2008) 3.43
Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A (2005) 3.37
Novel splice variants of the receptor for advanced glycation end-products expressed in human vascular endothelial cells and pericytes, and their putative roles in diabetes-induced vascular injury. Biochem J (2003) 3.29
An effective method for accurate prediction of the first hyperpolarizability of alkalides. J Comput Chem (2011) 3.28
Role of HMGB1 in apoptosis-mediated sepsis lethality. J Exp Med (2006) 3.26
Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism. Nature (2006) 3.21
Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus. Nature (2008) 3.06
In situ proteolysis for protein crystallization and structure determination. Nat Methods (2007) 3.05
Myeloid-derived suppressor cells suppress antitumor immune responses through IDO expression and correlate with lymph node metastasis in patients with breast cancer. J Immunol (2013) 2.96
Genetic evidence supports demic diffusion of Han culture. Nature (2004) 2.92
Phenotypic properties of transmitted founder HIV-1. Proc Natl Acad Sci U S A (2013) 2.75
A dual function of the CRISPR-Cas system in bacterial antivirus immunity and DNA repair. Mol Microbiol (2010) 2.70
Late gastrointestinal toxicities following radiation therapy for prostate cancer. Eur Urol (2011) 2.69
Wide variation in the multiplicity of HIV-1 infection among injection drug users. J Virol (2010) 2.67
Crystal structure of the CorA Mg2+ transporter. Nature (2006) 2.64
The Structural Biology Center 19ID undulator beamline: facility specifications and protein crystallographic results. J Synchrotron Radiat (2005) 2.62
An expression vector tailored for large-scale, high-throughput purification of recombinant proteins. Protein Expr Purif (2006) 2.58
Impact of comorbidity on survival among men with localized prostate cancer. J Clin Oncol (2011) 2.53
CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells. Cancer Res (2012) 2.50
Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice. Endocrinology (2007) 2.40
Dementia subtypes in China: prevalence in Beijing, Xian, Shanghai, and Chengdu. Arch Neurol (2005) 2.39
Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. J Virol (2010) 2.39
Biochemical and functional analysis of CTR1, a protein kinase that negatively regulates ethylene signaling in Arabidopsis. Plant J (2003) 2.37
Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy. J Am Coll Cardiol (2006) 2.37
NONCODEv4: exploring the world of long non-coding RNA genes. Nucleic Acids Res (2013) 2.37
Murine ccl2/cx3cr1 deficiency results in retinal lesions mimicking human age-related macular degeneration. Invest Ophthalmol Vis Sci (2007) 2.36
Genome-wide association identifies a susceptibility locus for coronary artery disease in the Chinese Han population. Nat Genet (2011) 2.32
Outcome of a workshop on archiving structural models of biological macromolecules. Structure (2006) 2.32
Volumetric texture analysis of breast lesions on contrast-enhanced magnetic resonance images. Magn Reson Med (2007) 2.31
A family of LIC vectors for high-throughput cloning and purification of proteins. Methods Mol Biol (2009) 2.30
Crystal structure of the TSP-1 type 1 repeats: a novel layered fold and its biological implication. J Cell Biol (2002) 2.28
Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor. Genes Dev (2006) 2.23
Is the 4 mm height of the vertebral artery groove really a limitation of C1 pedicle screw insertion? Eur Spine J (2014) 2.21
A synthetic homing endonuclease-based gene drive system in the human malaria mosquito. Nature (2011) 2.20
Autoreactive B cells in the marginal zone that express dual receptors. J Exp Med (2002) 2.16
Randomized study of autologous cytokine-induced killer cell immunotherapy in metastatic renal carcinoma. Clin Cancer Res (2012) 2.14
IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells. J Immunol (2010) 2.12
Structure of the influenza virus A H5N1 nucleoprotein: implications for RNA binding, oligomerization, and vaccine design. FASEB J (2008) 2.10
Outcome of a workshop on applications of protein models in biomedical research. Structure (2009) 2.05
Vertical T cell immunodominance and epitope entropy determine HIV-1 escape. J Clin Invest (2012) 2.05
Levels of prenatal mercury exposure and their relationships to neonatal anthropometry in Wujiang City, China. Environ Pollut (2013) 2.01
Generation of pig induced pluripotent stem cells with a drug-inducible system. J Mol Cell Biol (2009) 1.99
Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice. J Clin Invest (2007) 1.99
Overweight patients achieve ideal body weight following curative gastrectomy resulting in better long-term prognosis. Obes Surg (2013) 1.97
CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses. J Immunol (2006) 1.94
Enhanced differential evolution with adaptive strategies for numerical optimization. IEEE Trans Syst Man Cybern B Cybern (2010) 1.91
Understanding noncovalent interactions: ligand binding energy and catalytic efficiency from ligand-induced reductions in motion within receptors and enzymes. Angew Chem Int Ed Engl (2004) 1.90
Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet. EMBO J (2003) 1.89
A nation-wide multicenter 10-year (1999-2008) retrospective clinical epidemiological study of female breast cancer in China. BMC Cancer (2011) 1.88
Structure of RapA, a Swi2/Snf2 protein that recycles RNA polymerase during transcription. Structure (2008) 1.86
Advanced glycation endproduct-induced calcium handling impairment in mouse cardiac myocytes. J Mol Cell Cardiol (2002) 1.86
A PARALIND decomposition-based coherent two-dimensional direction of arrival estimation algorithm for acoustic vector-sensor arrays. Sensors (Basel) (2013) 1.84
Responses of ecosystem carbon cycle to experimental warming: a meta-analysis. Ecology (2013) 1.80
Triclinic lysozyme at 0.65 A resolution. Acta Crystallogr D Biol Crystallogr (2007) 1.77
Long-range ordered carbon clusters: a crystalline material with amorphous building blocks. Science (2012) 1.75
Structure of the CRISPR interference complex CSM reveals key similarities with cascade. Mol Cell (2013) 1.74
A multilevel adaptive finite element algorithm for bioluminescence tomography. Opt Express (2006) 1.71
Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry. Mol Cell Proteomics (2007) 1.71
Photoacoustic imaging of living mouse brain vasculature using hollow gold nanospheres. Biomaterials (2009) 1.70
Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis. Proc Natl Acad Sci U S A (2011) 1.69
Golgi protein 73 (GOLPH2) is a valuable serum marker for hepatocellular carcinoma. Gut (2010) 1.67
Energy decomposition analysis of covalent bonds and intermolecular interactions. J Chem Phys (2009) 1.66
Unidirectional monovalve homologous aortic patch for repair of ventricular septal defect with pulmonary hypertension. Ann Thorac Surg (2007) 1.66
Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases. Nat Struct Mol Biol (2008) 1.65
The noncoding RNA expression profile and the effect of lncRNA AK126698 on cisplatin resistance in non-small-cell lung cancer cell. PLoS One (2013) 1.65
Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China. Emerg Infect Dis (2004) 1.65
The crystal structure of spermidine synthase with a multisubstrate adduct inhibitor. Nat Struct Biol (2002) 1.63
Identification of unknown protein function using metabolite cocktail screening. Structure (2012) 1.62
Present Y chromosomes reveal the ancestry of Emperor CAO Cao of 1800 years ago. J Hum Genet (2011) 1.61
Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape. PLoS Pathog (2012) 1.61
Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli. J Biol Chem (2003) 1.61
Cancerous breast lesions on dynamic contrast-enhanced MR images: computerized characterization for image-based prognostic markers. Radiology (2010) 1.60
Body iron stores and dietary iron intake in relation to diabetes in adults in North China. Diabetes Care (2007) 1.59
Polarization-independent wide-angle triple-band metamaterial absorber. Opt Express (2011) 1.59
KASH protein Syne-2/Nesprin-2 and SUN proteins SUN1/2 mediate nuclear migration during mammalian retinal development. Hum Mol Genet (2010) 1.59
The role of miRNA-29 family in cancer. Eur J Cell Biol (2013) 1.58
Staphylococcus aureus IsdG and IsdI, heme-degrading enzymes with structural similarity to monooxygenases. J Biol Chem (2004) 1.58
Transcription factor AtMYB103 is required for anther development by regulating tapetum development, callose dissolution and exine formation in Arabidopsis. Plant J (2007) 1.58