PubRank

Helen R Saibil

Author PubWeight™ 64.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The protofilament structure of insulin amyloid fibrils. Proc Natl Acad Sci U S A 2002 4.08
2 Structural basis of pore formation by the bacterial toxin pneumolysin. Cell 2005 2.87
3 Structure of an Hsp90-Cdc37-Cdk4 complex. Mol Cell 2006 2.62
4 Structural basis for the regulated protease and chaperone function of DegP. Nature 2008 2.56
5 Structure of a type IV secretion system core complex. Science 2009 2.36
6 The structural basis for membrane binding and pore formation by lymphocyte perforin. Nature 2010 2.23
7 The TatA component of the twin-arginine protein transport system forms channel complexes of variable diameter. Proc Natl Acad Sci U S A 2005 2.02
8 Friend or foe: the same fold for attack and defense. Trends Immunol 2008 1.99
9 Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites. Nat Commun 2011 1.96
10 Allosteric signaling of ATP hydrolysis in GroEL-GroES complexes. Nat Struct Mol Biol 2006 1.94
11 Atomic structure and hierarchical assembly of a cross-β amyloid fibril. Proc Natl Acad Sci U S A 2013 1.75
12 The mechanism of pore formation by bacterial toxins. Curr Opin Struct Biol 2006 1.61
13 Atypical AAA+ subunit packing creates an expanded cavity for disaggregation by the protein-remodeling factor Hsp104. Cell 2007 1.56
14 Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack. Blood 2013 1.53
15 Topologies of a substrate protein bound to the chaperonin GroEL. Mol Cell 2007 1.52
16 Recognition and separation of single particles with size variation by statistical analysis of their images. J Mol Biol 2004 1.45
17 Detection and separation of heterogeneity in molecular complexes by statistical analysis of their two-dimensional projections. J Struct Biol 2007 1.45
18 The calcium channel alpha2delta-2 subunit partitions with CaV2.1 into lipid rafts in cerebellum: implications for localization and function. J Neurosci 2006 1.42
19 ATP-triggered conformational changes delineate substrate-binding and -folding mechanics of the GroEL chaperonin. Cell 2012 1.41
20 Visualization of macromolecular structures. Nat Methods 2010 1.34
21 Motor mechanism for protein threading through Hsp104. Mol Cell 2009 1.33
22 Structural analysis of substrate binding by the TatBC component of the twin-arginine protein transport system. Proc Natl Acad Sci U S A 2009 1.29
23 Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis. J Biol Chem 2005 1.24
24 Direct three-dimensional visualization of membrane disruption by amyloid fibrils. Proc Natl Acad Sci U S A 2012 1.24
25 Globular tetramers of beta(2)-microglobulin assemble into elaborate amyloid fibrils. J Mol Biol 2009 1.21
26 RNA channelling by the eukaryotic exosome. EMBO Rep 2010 1.16
27 Intrinsically disordered protein threads through the bacterial outer-membrane porin OmpF. Science 2013 1.13
28 Multiple states of a nucleotide-bound group 2 chaperonin. Structure 2008 1.11
29 Elongated oligomers assemble into mammalian PrP amyloid fibrils. J Mol Biol 2006 1.10
30 Chlamydiae assemble a pathogen synapse to hijack the host endoplasmic reticulum. Traffic 2012 1.09
31 Multiple distinct assemblies reveal conformational flexibility in the small heat shock protein Hsp26. Structure 2006 1.06
32 Structure determination of macromolecular assemblies by single-particle analysis of cryo-electron micrographs. Curr Opin Struct Biol 2004 1.06
33 A mutant chaperonin with rearranged inter-ring electrostatic contacts and temperature-sensitive dissociation. Nat Struct Mol Biol 2004 1.05
34 Folding with and without encapsulation by cis- and trans-only GroEL-GroES complexes. EMBO J 2003 1.01
35 Go hybrid: EM, crystallography, and beyond. Curr Opin Struct Biol 2012 1.01
36 Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity. Nat Commun 2013 1.00
37 Methods for three-dimensional reconstruction of heterogeneous assemblies. Methods Enzymol 2010 0.95
38 Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ. Nat Struct Mol Biol 2012 0.93
39 An expanded and flexible form of the vacuolar ATPase membrane sector. Structure 2006 0.92
40 Pathogen-host reorganization during Chlamydia invasion revealed by cryo-electron tomography. Cell Microbiol 2014 0.91
41 An expanded protein folding cage in the GroEL-gp31 complex. J Mol Biol 2006 0.90
42 Location of auxilin within a clathrin cage. J Mol Biol 2004 0.90
43 Cryo electron microscopy structures of Hsp100 proteins: crowbars in or out? Biochem Cell Biol 2010 0.88
44 ATP-driven molecular chaperone machines. Biopolymers 2013 0.86
45 Separating and visualising protein assemblies by means of preparative mass spectrometry and microscopy. J Struct Biol 2010 0.85