Published in Blood on June 15, 1990
The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor. Mol Cell Biol (1994) 2.69
Identification of endosialin, a cell surface glycoprotein of vascular endothelial cells in human cancer. Proc Natl Acad Sci U S A (1992) 1.62
Inhibition of the differentiation of human myeloid cell lines by redox changes induced through glutathione depletion. Biochem J (1994) 0.89
Production of interleukin 1beta by human hematopoietic progenitor cells. J Clin Invest (1996) 0.82
Differential regulation of the expression of interleukin-2 receptor gamma-chain during the in vitro differentiation of human myeloid cells. Biochem J (1995) 0.79
Platelets and smooth muscle cells affecting the differentiation of monocytes. PLoS One (2014) 0.75
Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice. Proc Natl Acad Sci U S A (1997) 5.44
T antigen repression of SV40 early transcription from two promoters. Cell (1981) 4.83
Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia. Nat Genet (2001) 4.79
Reversibility of acute B-cell leukaemia induced by BCR-ABL1. Nat Genet (2000) 3.67
AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia. Nat Med (2001) 3.47
CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors. Mol Cell Biol (1998) 3.19
Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. Proc Natl Acad Sci U S A (1999) 3.04
The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor. Mol Cell Biol (1994) 2.69
Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene. Nat Genet (1997) 2.64
CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter. Mol Cell Biol (1996) 2.42
PU.1 (Spi-1) and C/EBP alpha regulate the granulocyte colony-stimulating factor receptor promoter in myeloid cells. Blood (1996) 2.35
Thermolabile T (tumor) antigen from cells transformed by a temperature-sensitive mutant of simian virus 40. Proc Natl Acad Sci U S A (1975) 2.32
The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter. J Biol Chem (1993) 2.20
PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding. Blood (2000) 2.12
Monocyte antigen CD14 is a phospholipid anchored membrane protein. Blood (1989) 2.10
c-Myc is a critical target for c/EBPalpha in granulopoiesis. Mol Cell Biol (2001) 2.10
Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model. Blood (2000) 1.91
Identification of a region which directs the monocytic activity of the colony-stimulating factor 1 (macrophage colony-stimulating factor) receptor promoter and binds PEBP2/CBF (AML1). Mol Cell Biol (1994) 1.77
PU.1 (Spi-1) autoregulates its expression in myeloid cells. Oncogene (1995) 1.76
Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B. EMBO J (1997) 1.73
PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation. Immunity (1995) 1.72
Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells. J Immunol (1992) 1.72
Secreted phosphoproteins associated with neoplastic transformation: close homology with plasma proteins cleaved during blood coagulation. Cancer Res (1988) 1.71
PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene. Mol Cell Biol (1995) 1.70
Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1. Mol Cell Biol (1998) 1.69
Biological and biochemical studies of cells transformed by simian virus 40 temperature-sensitive gene A mutants and A mutant revertants. J Virol (1977) 1.64
The CD11b promoter directs high-level expression of reporter genes in macrophages in transgenic mice. Blood (1995) 1.61
Neutrophils and monocytes express high levels of PU.1 (Spi-1) but not Spi-B. Blood (1995) 1.60
Temporal mapping of gene expression levels during the differentiation of individual primary hematopoietic cells. Proc Natl Acad Sci U S A (1996) 1.51
Inhibition of hematopoiesis by competitive binding of transcription factor PU.1. Proc Natl Acad Sci U S A (1994) 1.51
CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing. Proc Natl Acad Sci U S A (1997) 1.50
Overcoming limitations of the mRNA differential display technique. Nucleic Acids Res (1995) 1.49
c-Jun is a JNK-independent coactivator of the PU.1 transcription factor. J Biol Chem (1999) 1.49
Dichotomy of AML1-ETO functions: growth arrest versus block of differentiation. Mol Cell Biol (2001) 1.46
Binding of an analog of the simian virus 40 T antigen to wild-type and mutant viral replication origins. J Mol Biol (1982) 1.42
Acute myelogenous leukemia: current treatment and future directions. Am J Med (1992) 1.42
Binding of simian virus 40 large T antigen from virus-infected monkey cells to wild-type and mutant viral replication origins. J Mol Biol (1983) 1.38
The Sp1 transcription factor binds the CD11b promoter specifically in myeloid cells in vivo and is essential for myeloid-specific promoter activity. J Biol Chem (1993) 1.38
Molecular cloning of the human eosinophil-derived neurotoxin: a member of the ribonuclease gene family. Proc Natl Acad Sci U S A (1989) 1.35
Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3). J Cell Biol (1988) 1.35
Site-specific DNA methylation by a complex of PU.1 and Dnmt3a/b. Oncogene (2006) 1.35
Depletion of RUNX1/ETO in t(8;21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding. Leukemia (2012) 1.35
Purification of a human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin. Biochim Biophys Acta (1989) 1.33
Differential expression of CD11b/CD18 (Mo1) and myeloperoxidase genes during myeloid differentiation. Blood (1989) 1.32
Human eosinophil cationic protein. Molecular cloning of a cytotoxin and helminthotoxin with ribonuclease activity. J Exp Med (1989) 1.29
Regulation of the PU.1 gene by distal elements. Blood (2001) 1.28
Characterization of the myeloid-specific CD11b promoter. Blood (1992) 1.28
Synergistic up-regulation of the myeloid-specific promoter for the macrophage colony-stimulating factor receptor by AML1 and the t(8;21) fusion protein may contribute to leukemogenesis. Proc Natl Acad Sci U S A (1996) 1.28
Regulation of CD14 expression during monocytic differentiation induced with 1 alpha,25-dihydroxyvitamin D3. J Immunol (1994) 1.24
Sp1 is a critical factor for the monocytic specific expression of human CD14. J Biol Chem (1994) 1.22
Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein alpha (C/EBP alpha) is critical for granulopoiesis. J Exp Med (1998) 1.19
Function of PU.1 (Spi-1), C/EBP, and AML1 in early myelopoiesis: regulation of multiple myeloid CSF receptor promoters. Curr Top Microbiol Immunol (1996) 1.18
Overexpression of TRIB2 in human lung cancers contributes to tumorigenesis through downregulation of C/EBPα. Oncogene (2011) 1.17
Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha. Nucleic Acids Res (1998) 1.17
Monocyte chemoattractant protein-1 gene is expressed in activated neutrophils and retinoic acid-induced human myeloid cell lines. Blood (1994) 1.17
PML-RARalpha initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors. Leukemia (2009) 1.16
Purification of simian virus 40 tumor antigen from a line of simian virus 40-transformed human cells. Proc Natl Acad Sci U S A (1977) 1.14
Use of a promoterless Renilla luciferase vector as an internal control plasmid for transient co-transfection assays of Ras-mediated transcription activation. Biotechniques (1999) 1.13
Point mutations impairing cell surface expression of the common beta subunit (CD18) in a patient with leukocyte adhesion molecule (Leu-CAM) deficiency. J Clin Invest (1990) 1.12
Optimization of transient transfection into human myeloid cell lines using a luciferase reporter gene. Exp Hematol (1991) 1.09
Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains. Mol Cell Biol (1999) 1.09
Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML. Leukemia (2010) 1.07
Structure of the gene encoding CD34, a human hematopoietic stem cell antigen. Genomics (1992) 1.06
An alternative method for labeling oligonucleotide probes for screening cDNA libraries. Biotechniques (1990) 1.03
Effect of a stem-loop structure within the SV40 replication origin upon SV40 T antigen binding to origin region sequences. Cell (1983) 0.99
Octamer binding factors and their coactivator can activate the murine PU.1 (spi-1) promoter. J Biol Chem (1996) 0.98
PU.1 induces apoptosis in myeloma cells through direct transactivation of TRAIL. Oncogene (2009) 0.93
Multiple control elements are required for expression of the human CD34 gene. Gene (1998) 0.92
Cloning and analysis of the CD18 promoter. Blood (1992) 0.90
Cooperative interaction between ETS1 and GFI1 transcription factors in the repression of Bax gene expression. Oncogene (2007) 0.89
The human CD34 hematopoietic stem cell antigen promoter and a 3' enhancer direct hematopoietic expression in tissue culture. Blood (1992) 0.88
The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties. Proc Natl Acad Sci U S A (1996) 0.88
Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrins. Proc Natl Acad Sci U S A (1988) 0.87
Identification and characterization of a functional promoter region in the human eosinophil IL-5 receptor alpha subunit gene. J Biol Chem (1995) 0.86
Molecular cloning and characterization of human eosinophil Charcot-Leyden crystal protein (lysophospholipase). Similarities to IgE binding proteins and the S-type animal lectin superfamily. J Immunol (1993) 0.86
A nuclear factor Y (NFY) site positively regulates the human CD34 stem cell gene. Blood (1999) 0.85
Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link. Leukemia (2006) 0.85
Prophylaxis and therapy with factor VII concentrate (human) immuno, vapor heated in patients with congenital factor VII deficiency: a summary of case reports. Am J Hematol (1995) 0.84
Two promoters direct expression of the murine Spi-B gene, an Ets family transcription factor. Gene (1998) 0.84
Characterization of a distinct binding site for the prokaryotic chaperone, GroEL, on a human granulocyte ribonuclease. J Biol Chem (1993) 0.82
Functional characterization of the promoter for the gene encoding human eosinophil peroxidase. J Biol Chem (1994) 0.82
Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties. Curr Top Microbiol Immunol (1996) 0.81
The gene for human eosinophil Charcot-Leyden crystal protein directs expression of lysophospholipase activity and spontaneous crystallization in transiently transfected COS cells. J Leukoc Biol (1992) 0.79
Formation of a cruciform structure at the simian virus 40 replication origin abolishes T-antigen binding to the origin in vitro. J Virol (1985) 0.79
Rapid cDNA library screening using the polymerase chain reaction. Biotechniques (1991) 0.79
Identification of Sp1-binding sites in the CD11c (p150,95 alpha) and CD11a (LFA-1 alpha) integrin subunit promoters and their involvement in the tissue-specific expression of CD11c. Eur J Immunol (1995) 0.78
Human eosinophil Charcot-Leyden crystal protein: cloning and characterization of a lysophospholipase gene promoter. Blood (1993) 0.78
C/EBPβ promotes BCR-ABL-mediated myeloid expansion and leukemic stem cell exhaustion. Leukemia (2012) 0.78
Interleukin-5 receptor alpha subunit gene regulation in human eosinophil development: identification of a unique cis-element that acts lie an enhancer in regulating activity of the IL-5R alpha promoter. Curr Top Microbiol Immunol (1996) 0.77
Analysis of the modulation of transcriptional activity in myelopoiesis and leukemogenesis. Methods (1999) 0.77
Mutations of the transcription factor PU.1 are not associated with acute lymphoblastic leukaemia. Br J Cancer (2006) 0.76
Chromosome 1 localization of the gene for CD34, a surface antigen of human stem cells. Cytogenet Cell Genet (1990) 0.76
Transcriptional regulation of the human eosinophil peroxidase genes: characterization of a peroxidase promoter. Int Arch Allergy Immunol (1994) 0.76
Acute and chronic leukemias in adults. CA Cancer J Clin (1994) 0.75
Multiple sclerosis: getting personal with induced pluripotent stem cells. Cell Death Dis (2016) 0.75
Functional characterization of the promoter for the gene encoding murine CD34. Biochim Biophys Acta (1997) 0.75