Published in J Biol Chem on August 24, 2006
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy (2016) 7.05
Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. J Immunol (2009) 1.52
HIV-1 Vpu blocks recycling and biosynthetic transport of the intrinsic immunity factor CD317/tetherin to overcome the virion release restriction. MBio (2011) 1.30
Oxidative stress in the pathology and treatment of systemic lupus erythematosus. Nat Rev Rheumatol (2013) 1.27
Total antioxidant capacity--a novel early bio-chemical marker of oxidative stress in HIV infected individuals. J Biomed Sci (2009) 1.13
Central role of nitric oxide in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus. Arthritis Res Ther (2010) 1.05
Pathogenic mechanisms in systemic lupus erythematosus. Autoimmunity (2010) 1.02
Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome. Curr Opin Rheumatol (2009) 0.99
HRES-1/Rab4-mediated depletion of Drp1 impairs mitochondrial homeostasis and represents a target for treatment in SLE. Ann Rheum Dis (2013) 0.97
Endogenous retroviral pathogenesis in lupus. Curr Opin Rheumatol (2010) 0.95
Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon. Nucleic Acids Res (2010) 0.94
T-cell and B-cell signaling biomarkers and treatment targets in lupus. Curr Opin Rheumatol (2009) 0.94
Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE. Autoimmunity (2008) 0.93
Systems biology of lupus: mapping the impact of genomic and environmental factors on gene expression signatures, cellular signaling, metabolic pathways, hormonal and cytokine imbalance, and selecting targets for treatment. Autoimmunity (2010) 0.92
Human Endogenous Retroviruses (HERVs) and Autoimmune Rheumatic Disease: Is There a Link? Open Rheumatol J (2013) 0.90
Infection in systemic lupus erythematosus: friend or foe? Int J Clin Rheumtol (2010) 0.85
HRES-1/Rab4 promotes the formation of LC3(+) autophagosomes and the accumulation of mitochondria during autophagy. PLoS One (2014) 0.84
DNA methylation modulates HRES1/p28 expression in B cells from patients with Lupus. Autoimmunity (2013) 0.84
Metabolic regulation of organelle homeostasis in lupus T cells. Clin Immunol (2012) 0.81
Extracellular superoxide dismutase activity and plasma malondialdehyde in human immunodeficiency virus subjects of kano state as surrogate markers of CD4 status. Int J Biomed Sci (2010) 0.77
Metabolic control of the epigenome in systemic Lupus erythematosus. Autoimmunity (2013) 0.76
Mitochondrial Dysfunction in the Liver and Antiphospholipid Antibody Production Precede Disease Onset and Respond to Rapamycin in Lupus-Prone Mice. Arthritis Rheumatol (2016) 0.76
Genome-wide association study of antibody responses to Plasmodium falciparum candidate vaccine antigens. Genes Immun (2016) 0.75
Antiretroviral Therapy Initiation Alters the Redox System of Asymptomatic HIV-Infected Individuals: A Longitudinal Study. Oxid Med Cell Longev (2017) 0.75
Editorial: LINEing Up to Boost Interferon Production: Activation of Endogenous Retroviral DNA in Autoimmunity. Arthritis Rheumatol (2016) 0.75
Oxidative stress and endosome recycling are complementary mechanisms reorganizing the T-cell receptor signaling complex in SLE. Clin Immunol (2011) 0.75
Vesicular Trafficking to the Immune Synapse: How to Assemble Receptor-Tailored Pathways from a Basic Building Set. Front Immunol (2016) 0.75
Induction of systemic lupus erythematosus with tumor necrosis factor blockers. J Rheumatol (2010) 2.89
Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus. Arthritis Rheum (2002) 2.08
Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation. J Biol Chem (2005) 1.78
Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus. Arthritis Rheum (2006) 1.76
Prevention of hepatocarcinogenesis and increased susceptibility to acetaminophen-induced liver failure in transaldolase-deficient mice by N-acetylcysteine. J Clin Invest (2009) 1.75
Abnormal T cell signal transduction in systemic lupus erythematosus. Arthritis Rheum (2002) 1.62
Mitochondrial hyperpolarization: a checkpoint of T-cell life, death and autoimmunity. Trends Immunol (2004) 1.56
Nitric oxide-dependent mitochondrial biogenesis generates Ca2+ signaling profile of lupus T cells. J Immunol (2004) 1.54
Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. J Immunol (2009) 1.52
Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals. PLoS Pathog (2008) 1.44
T cell activation-induced mitochondrial hyperpolarization is mediated by Ca2+- and redox-dependent production of nitric oxide. J Immunol (2003) 1.39
N-acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum (2012) 1.38
Evaluation of the renal effects of experimental feeding of melamine and cyanuric acid to fish and pigs. Am J Vet Res (2008) 1.36
Metabolic control of T cell activation and death in SLE. Autoimmun Rev (2008) 1.28
T- and B-cell abnormalities in systemic lupus erythematosus. Crit Rev Immunol (2005) 1.27
Distinct hsp70 domains mediate apoptosis-inducing factor release and nuclear accumulation. J Biol Chem (2006) 1.21
mTOR signaling: a central pathway to pathogenesis in systemic lupus erythematosus? Discov Med (2010) 1.21
Hsp72 and stress kinase c-jun N-terminal kinase regulate the bid-dependent pathway in tumor necrosis factor-induced apoptosis. Mol Cell Biol (2002) 1.17
siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells. Hum Mol Genet (2008) 1.15
Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus. Arthritis Rheum (2011) 1.13
The R1 subunit of herpes simplex virus ribonucleotide reductase protects cells against apoptosis at, or upstream of, caspase-8 activation. J Gen Virol (2002) 1.09
Fatal toxic myopathy attributed to propofol, methylprednisolone, and cyclosporine after prior exposure to colchicine and simvastatin. Clin Rheumatol (2007) 1.08
Psychiatric symptoms in systemic lupus erythematosus: a systematic review. J Clin Psychiatry (2012) 1.08
Oxidative stress, inflammation and carcinogenesis are controlled through the pentose phosphate pathway by transaldolase. Trends Mol Med (2011) 1.06
Key concepts of clinical trials: a narrative review. Postgrad Med (2011) 1.05
Central role of nitric oxide in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus. Arthritis Res Ther (2010) 1.05
Apoptosis and mitochondrial dysfunction in lymphocytes of patients with systemic lupus erythematosus. Methods Mol Med (2004) 1.04
Metabolic switches of T-cell activation and apoptosis. Antioxid Redox Signal (2002) 1.04
Mechanistic target of rapamycin complex 1 expands Th17 and IL-4+ CD4-CD8- double-negative T cells and contracts regulatory T cells in systemic lupus erythematosus. J Immunol (2014) 1.03
Pathogenic mechanisms in systemic lupus erythematosus. Autoimmunity (2010) 1.02
HSP72 inhibits apoptosis-inducing factor release in ATP-depleted renal epithelial cells. Am J Physiol Cell Physiol (2003) 1.02
Emerging new pathways of pathogenesis and targets for treatment in systemic lupus erythematosus and Sjogren's syndrome. Curr Opin Rheumatol (2009) 0.99
Mitochondrial dysfunction in T cells of patients with systemic lupus erythematosus. Int Rev Immunol (2004) 0.99
Mechanistic target of rapamycin activation triggers IL-4 production and necrotic death of double-negative T cells in patients with systemic lupus erythematosus. J Immunol (2013) 0.99
T lymphocytes from patients with systemic lupus erythematosus are resistant to induction of autophagy. FASEB J (2012) 0.99
Association of common mitochondrial DNA variants with multiple sclerosis and systemic lupus erythematosus. Clin Immunol (2008) 0.96
Murine lupus susceptibility locus Sle1c2 mediates CD4+ T cell activation and maps to estrogen-related receptor γ. J Immunol (2012) 0.96
Endogenous retroviral pathogenesis in lupus. Curr Opin Rheumatol (2010) 0.95
Haplotypes of the HRES-1 endogenous retrovirus are associated with development and disease manifestations of systemic lupus erythematosus. Arthritis Rheum (2008) 0.95
T-cell and B-cell signaling biomarkers and treatment targets in lupus. Curr Opin Rheumatol (2009) 0.94
Nitric oxide, mitochondrial hyperpolarization, and T cell activation. Free Radic Biol Med (2007) 0.94
Transaldolase is essential for maintenance of the mitochondrial transmembrane potential and fertility of spermatozoa. Proc Natl Acad Sci U S A (2006) 0.94
Regulation of apoptosis by heat shock proteins. IUBMB Life (2014) 0.93
Increased prevalence of transfusion-transmitted virus and cross-reactivity with immunodominant epitopes of the HRES-1/p28 endogenous retroviral autoantigen in patients with systemic lupus erythematosus. Clin Immunol (2005) 0.93
Gender-specific expression and mechanism of regulation of estrogen sulfotransferase in adipose tissues of the mouse. Endocrinology (2008) 0.93
Molecular mimicry and immunomodulation by the HRES-1 endogenous retrovirus in SLE. Autoimmunity (2008) 0.93
Immunofluorescence microscopy is superior to fluorescent beads for detection of antinuclear antibody reactivity in systemic lupus erythematosus patients. Clin Immunol (2007) 0.93
Adhesion-dependent Skp2 transcription requires selenocysteine tRNA gene transcription-activating factor (STAF). Biochem J (2011) 0.92
Nitric oxide production of T lymphocytes is increased in rheumatoid arthritis. Immunol Lett (2008) 0.91
Antinucleosome antibodies and decreased deoxyribonuclease activity in sera of patients with systemic lupus erythematosus. Clin Diagn Lab Immunol (2005) 0.91
Transaldolase deficiency influences the pentose phosphate pathway, mitochondrial homoeostasis and apoptosis signal processing. Biochem J (2008) 0.91
Pharmacotherapy of systemic lupus erythematosus. Expert Opin Pharmacother (2009) 0.91
ZNF143 mediates basal and tissue-specific expression of human transaldolase. J Biol Chem (2003) 0.91
Increased mitochondrial electron transport chain activity at complex I is regulated by N-acetylcysteine in lymphocytes of patients with systemic lupus erythematosus. Antioxid Redox Signal (2014) 0.90
hsp72 inhibits focal adhesion kinase degradation in ATP-depleted renal epithelial cells. J Biol Chem (2003) 0.90
Block of HERG channels by berberine: mechanisms of voltage- and state-dependence probed with site-directed mutant channels. J Cardiovasc Pharmacol (2006) 0.88
Tuberous sclerosis and fulminant lupus in a young woman. J Clin Rheumatol (2013) 0.88
The effect of balneotherapy on C-reactive protein, serum cholesterol, triglyceride, total antioxidant status and HSP-60 levels. Int J Biometeorol (2009) 0.87
Interplay of infections, autoimmunity, and immunosuppression in systemic lupus erythematosus. Int Rev Immunol (2014) 0.87
Detection of lupus anticoagulant and successful anticoagulation in familial Sneddon syndrome. Ann Rheum Dis (2010) 0.87
CD8+ T cell-mediated HLA-A*0201-restricted cytotoxicity to transaldolase peptide 168-176 in patients with multiple sclerosis. J Immunol (2005) 0.87
CCL genes in multiple sclerosis and systemic lupus erythematosus. J Neuroimmunol (2008) 0.86
Signaling abnormalities in systemic lupus erythematosus as potential drug targets. Endocr Metab Immune Disord Drug Targets (2006) 0.86