James L Keck

Author PubWeight™ 60.56‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 SSB as an organizer/mobilizer of genome maintenance complexes. Crit Rev Biochem Mol Biol 2008 3.19
2 High-resolution structure of the E.coli RecQ helicase catalytic core. EMBO J 2003 2.61
3 The HRDC domain of BLM is required for the dissolution of double Holliday junctions. EMBO J 2005 1.84
4 Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75. Nat Struct Mol Biol 2008 1.78
5 A central role for SSB in Escherichia coli RecQ DNA helicase function. J Biol Chem 2007 1.66
6 Binding mechanism of metal⋅NTP substrates and stringent-response alarmones to bacterial DnaG-type primases. Structure 2012 1.64
7 Helix bundle quaternary structure from alpha/beta-peptide foldamers. J Am Chem Soc 2007 1.54
8 Structural basis of Escherichia coli single-stranded DNA-binding protein stimulation of exonuclease I. Proc Natl Acad Sci U S A 2008 1.42
9 Domain mapping of Escherichia coli RecQ defines the roles of conserved N- and C-terminal regions in the RecQ family. Nucleic Acids Res 2003 1.41
10 Conferring substrate specificity to DNA helicases: role of the RecQ HRDC domain. Structure 2005 1.40
11 Structural basis of the Sir1-origin recognition complex interaction in transcriptional silencing. Proc Natl Acad Sci U S A 2005 1.35
12 Structure of the calcium-rich signature domain of human thrombospondin-2. Nat Struct Mol Biol 2005 1.33
13 Crystal structure of the Deinococcus radiodurans single-stranded DNA-binding protein suggests a mechanism for coping with DNA damage. Proc Natl Acad Sci U S A 2004 1.33
14 The origin recognition complex and Sir4 protein recruit Sir1p to yeast silent chromatin through independent interactions requiring a common Sir1p domain. Mol Cell Biol 2004 1.30
15 Structure and function of RecQ DNA helicases. Crit Rev Biochem Mol Biol 2004 1.29
16 A hand-off mechanism for primosome assembly in replication restart. Mol Cell 2007 1.27
17 Structure of the SSB-DNA polymerase III interface and its role in DNA replication. EMBO J 2011 1.23
18 Identification of the SSB binding site on E. coli RecQ reveals a conserved surface for binding SSB's C terminus. J Mol Biol 2009 1.20
19 Structural determinants of DNA binding by a P. falciparum ApiAP2 transcriptional regulator. J Mol Biol 2009 1.17
20 PriB stimulates PriA helicase via an interaction with single-stranded DNA. J Biol Chem 2005 1.15
21 Genetic recombination in Bacillus subtilis: a division of labor between two single-strand DNA-binding proteins. Nucleic Acids Res 2012 1.08
22 Structure and function of the regulatory C-terminal HRDC domain from Deinococcus radiodurans RecQ. Nucleic Acids Res 2008 1.07
23 Three HRDC domains differentially modulate Deinococcus radiodurans RecQ DNA helicase biochemical activity. J Biol Chem 2006 1.05
24 Structure and cellular roles of the RMI core complex from the bloom syndrome dissolvasome. Structure 2010 1.05
25 Sit down, relax and unwind: structural insights into RecQ helicase mechanisms. Nucleic Acids Res 2006 1.05
26 Structural mechanisms of PriA-mediated DNA replication restart. Proc Natl Acad Sci U S A 2013 1.05
27 Catalytic activation of histone acetyltransferase Rtt109 by a histone chaperone. Proc Natl Acad Sci U S A 2010 1.03
28 Coupling DNA-binding and ATP hydrolysis in Escherichia coli RecQ: role of a highly conserved aromatic-rich sequence. Nucleic Acids Res 2005 1.00
29 Crystal structure of PriB, a component of the Escherichia coli replication restart primosome. Structure 2004 0.98
30 Structure and cellular dynamics of Deinococcus radiodurans single-stranded DNA (ssDNA)-binding protein (SSB)-DNA complexes. J Biol Chem 2012 0.97
31 PriC-mediated DNA replication restart requires PriC complex formation with the single-stranded DNA-binding protein. J Biol Chem 2013 0.97
32 Rising from the Ashes: DNA Repair in Deinococcus radiodurans. PLoS Genet 2010 0.97
33 The BLM dissolvasome in DNA replication and repair. Cell Mol Life Sci 2013 0.97
34 Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome. Proc Natl Acad Sci U S A 2012 0.96
35 Peptide inhibitors identify roles for SSB C-terminal residues in SSB/exonuclease I complex formation. Biochemistry 2009 0.96
36 Structure of the Sir3 protein bromo adjacent homology (BAH) domain from S. cerevisiae at 1.95 A resolution. Protein Sci 2006 0.95
37 The Deinococcus radiodurans DR1245 protein, a DdrB partner homologous to YbjN proteins and reminiscent of type III secretion system chaperones. PLoS One 2013 0.89
38 Mechanism of Exonuclease I stimulation by the single-stranded DNA-binding protein. Nucleic Acids Res 2011 0.87
39 Grip it and rip it: structural mechanisms of DNA helicase substrate binding and unwinding. Protein Sci 2014 0.86
40 Structure and biochemical activities of Escherichia coli MgsA. J Biol Chem 2011 0.85
41 Influences of the N700S thrombospondin-1 polymorphism on protein structure and stability. J Biol Chem 2008 0.85
42 Neisseria gonorrhoeae RecQ helicase HRDC domains are essential for efficient binding and unwinding of the pilE guanine quartet structure required for pilin antigenic variation. J Bacteriol 2013 0.85
43 Small-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance. Proc Natl Acad Sci U S A 2009 0.83
44 Protein interactions in genome maintenance as novel antibacterial targets. PLoS One 2013 0.83
45 The primase domain of PfPrex is a proteolytically matured, essential enzyme of the apicoplast. Mol Biochem Parasitol 2011 0.82
46 Creating directed double-strand breaks with the Ref protein: a novel RecA-dependent nuclease from bacteriophage P1. J Biol Chem 2010 0.82
47 RecQ DNA helicase HRDC domains are critical determinants in Neisseria gonorrhoeae pilin antigenic variation and DNA repair. Mol Microbiol 2008 0.81
48 RecD2 helicase limits replication fork stress in Bacillus subtilis. J Bacteriol 2014 0.80
49 Werner helicase wings DNA binding. Structure 2010 0.79
50 Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae. Biochemistry 2011 0.78
51 Magic spots cast a spell on DNA primase. Cell 2007 0.77
52 X-ray crystal structure of the bacterial conjugation factor PsiB, a negative regulator of RecA. J Biol Chem 2010 0.76
53 Molecular biology: Slip sliding on DNA. Nature 2009 0.75