Published in Mol Cancer Res on August 28, 2006
Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface. ACS Chem Biol (2007) 1.84
Negative regulation of hypoxic responses via induced Reptin methylation. Mol Cell (2010) 1.68
Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition. Mol Cancer Ther (2009) 1.67
The unique characteristics of tumor vasculature and preclinical evidence for its selective disruption by Tumor-Vascular Disrupting Agents. Cancer Treat Rev (2010) 1.64
Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy. Proc Natl Acad Sci U S A (2007) 1.63
HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses. Proc Natl Acad Sci U S A (2009) 1.59
Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1alpha/Sp4. Mol Cancer Ther (2009) 1.37
Overcoming disappointing results with antiangiogenic therapy by targeting hypoxia. Nat Rev Clin Oncol (2012) 1.37
Identification of a novel small molecule HIF-1alpha translation inhibitor. Clin Cancer Res (2009) 1.33
Prognostic significance of Hypoxia-Inducible Factor 1 alpha(HIF-1 alpha) expression in serous ovarian cancer: an immunohistochemical study. BMC Cancer (2008) 1.02
Hypoxic signature of microRNAs in glioblastoma: insights from small RNA deep sequencing. BMC Genomics (2014) 1.00
Design and synthesis of novel small-molecule inhibitors of the hypoxia inducible factor pathway. J Med Chem (2011) 0.99
Hypoxia inducible factor-1alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death. Am J Pathol (2008) 0.95
A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. J Am Chem Soc (2013) 0.92
Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents. J Med Chem (2012) 0.89
Hypoxia-induced autophagy mediates cisplatin resistance in lung cancer cells. Sci Rep (2015) 0.88
Potent inhibition of tumoral hypoxia-inducible factor 1alpha by albendazole. BMC Cancer (2010) 0.88
Isolation of hypoxia-inducible factor 1 (HIF-1) inhibitors from frankincense using a molecularly imprinted polymer. Invest New Drugs (2010) 0.86
Hypoxia, stem cells and bone tumor. Cancer Lett (2011) 0.86
Requirement of evading apoptosis for HIF-1α-induced malignant progression in mouse cells. Cell Cycle (2011) 0.85
From antiangiogenesis to hypoxia: current research and future directions. Cancer Manag Res (2010) 0.84
MFTZ-1 reduces constitutive and inducible HIF-1α accumulation and VEGF secretion independent of its topoisomerase II inhibition. J Cell Mol Med (2010) 0.84
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Andrographolide inhibits hypoxia-inducible factor-1 through phosphatidylinositol 3-kinase/AKT pathway and suppresses breast cancer growth. Onco Targets Ther (2015) 0.82
Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation. Invest New Drugs (2009) 0.82
MicroRNA-454 regulates stromal cell derived factor-1 in the control of the growth of pancreatic ductal adenocarcinoma. Sci Rep (2016) 0.82
Dietary administration of scallion extract effectively inhibits colorectal tumor growth: cellular and molecular mechanisms in mice. PLoS One (2012) 0.82
Dual inhibition of plasminogen kringle 5 on angiogenesis and chemotaxis suppresses tumor metastasis by targeting HIF-1α pathway. PLoS One (2012) 0.81
Optical imaging probes in oncology. Oncotarget (2016) 0.81
Macrophage migration inhibitory factor manipulation and evaluation in tumoral hypoxic adaptation. Methods Enzymol (2007) 0.81
Mitochondria, cholesterol and cancer cell metabolism. Clin Transl Med (2016) 0.80
Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer. Oncotarget (2015) 0.79
The expression level of the transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) determines cellular survival after radiation treatment. Radiat Oncol (2015) 0.77
Paradoxical regulation of hypoxia inducible factor-1α (HIF-1α) by histone deacetylase inhibitor in diffuse large B-cell lymphoma. PLoS One (2013) 0.76
Biological characteristics of prostate cancer cells are regulated by hypoxia-inducible factor 1α Oncol Lett (2014) 0.76
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Molecular-targeted therapy hypoxia in head and neck squamous cell carcinoma patients. Mol Clin Oncol (2012) 0.75
Neuronal cell fate decisions: O2 and CO2 sensing neurons require egl-13/Sox5. Worm (2013) 0.75
Integrin beta-8 (ITGB8) silencing reverses gefitinib resistance of human hepatic cancer HepG2/G cell line. Int J Clin Exp Med (2015) 0.75
The Impact of the "Yogic Lifestyle" on Cancer Prognosis and Survival: Can we Target Cancer Stem Cells with Yoga? Int J Yoga (2017) 0.75