Published in Exp Cell Res on August 05, 2006
Surface antigen phenotypes of hematopoietic stem cells from embryos and murine embryonic stem cells. Blood (2009) 1.51
Hematopoietic cell differentiation from embryonic and induced pluripotent stem cells. Stem Cell Res Ther (2013) 0.85
Challenges and strategies for generating therapeutic patient-specific hemangioblasts and hematopoietic stem cells from human pluripotent stem cells. Int J Dev Biol (2010) 0.83
Serum- and stromal cell-free hypoxic generation of embryonic stem cell-derived hematopoietic cells in vitro, capable of multilineage repopulation of immunocompetent mice. Stem Cells Transl Med (2012) 0.82
Induction of hematopoietic differentiation of mouse embryonic stem cells by an AGM-derived stromal cell line is not further enhanced by overexpression of HOXB4. Stem Cells Dev (2010) 0.81
Enhanced generation of myeloid lineages in hematopoietic differentiation from embryonic stem cells by silencing transcriptional repressor Twist-2. Cloning Stem Cells (2009) 0.77
Formation of embryoid bodies using dielectrophoresis. Biomicrofluidics (2012) 0.76
Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter. Nature (2009) 5.34
Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell Stem Cell (2010) 5.05
In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium. Nature (2010) 4.16
Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. Immunity (2002) 4.15
Generation of functional human hepatic endoderm from human induced pluripotent stem cells. Hepatology (2010) 3.36
Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta. Immunity (2002) 3.06
Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling. Proc Natl Acad Sci U S A (2008) 2.99
GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells. J Exp Med (2004) 2.94
The murine placenta contains hematopoietic stem cells within the vascular labyrinth region. Dev Cell (2005) 2.91
Hematopoietic stem cell development is dependent on blood flow. Cell (2009) 2.77
Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches. Cell Stem Cell (2008) 2.74
Human placenta is a potent hematopoietic niche containing hematopoietic stem and progenitor cells throughout development. Cell Stem Cell (2009) 1.85
Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development (2010) 1.81
Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells. Cell Stem Cell (2011) 1.76
Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1. EMBO J (2008) 1.71
Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo. Cancer Cell (2013) 1.68
WNT signaling drives cholangiocarcinoma growth and can be pharmacologically inhibited. J Clin Invest (2015) 1.68
Sca-1 negatively regulates proliferation and differentiation of muscle cells. Dev Biol (2005) 1.66
Whole-mount three-dimensional imaging of internally localized immunostained cells within mouse embryos. Nat Protoc (2012) 1.58
The Ly-6A (Sca-1) GFP transgene is expressed in all adult mouse hematopoietic stem cells. Stem Cells (2002) 1.56
An unexpected role for IL-3 in the embryonic development of hematopoietic stem cells. Dev Cell (2006) 1.55
Human cord blood-derived cells can differentiate into hepatocytes in the mouse liver with no evidence of cellular fusion. Gastroenterology (2003) 1.55
Mesenchymal lineage potentials of aorta-gonad-mesonephros stromal clones. Haematologica (2006) 1.51
Sustained expansion and transgene expression of coagulation factor VIII-transduced cord blood-derived endothelial progenitor cells. Arterioscler Thromb Vasc Biol (2003) 1.50
Characterisation of a stereotypical cellular and extracellular adult liver progenitor cell niche in rodents and diseased human liver. Gut (2010) 1.44
Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells. Proc Natl Acad Sci U S A (2007) 1.42
The constituents and mechanisms of generation of 'endothelial cell--colony forming units'. Cardiovasc Res (2013) 1.41
Hematopoietic stem cell development requires transient Wnt/β-catenin activity. J Exp Med (2012) 1.35
Acute multiple organ failure in adult mice deleted for the developmental regulator Wt1. PLoS Genet (2011) 1.27
Gata2 is required for HSC generation and survival. J Exp Med (2013) 1.26
CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells. Blood (2011) 1.23
Bone marrow-derived SP cells can contribute to the respiratory tract of mice in vivo. J Cell Sci (2005) 1.21
Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling. Proc Natl Acad Sci U S A (2013) 1.20
DNA ligase I null mouse cells show normal DNA repair activity but altered DNA replication and reduced genome stability. J Cell Sci (2002) 1.18
Persistence of functional hepatocyte-like cells in immune-compromised mice. Liver Int (2010) 1.18
Mesenchymal progenitor cells localize within hematopoietic sites throughout ontogeny. Development (2005) 1.16
Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling. J Exp Med (2012) 1.13
A murine specific expansion of the Rhox cluster involved in embryonic stem cell biology is under natural selection. BMC Genomics (2006) 1.12
The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization. Blood (2011) 1.12
Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis. Cell Stem Cell (2012) 1.11
Restoration of Runx1 expression in the Tie2 cell compartment rescues definitive hematopoietic stem cells and extends life of Runx1 knockout animals until birth. Stem Cells (2009) 1.10
The inhibitory role of stromal cell mesenchyme on human embryonic stem cell hepatocyte differentiation is overcome by Wnt3a treatment. Cloning Stem Cells (2008) 1.09
Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15. Exp Hematol (2008) 1.09
The comparison between conditioned media and serum-free media in human embryonic stem cell culture and differentiation. Cell Reprogram (2010) 1.08
Late outgrowth endothelial cells resemble mature endothelial cells and are not derived from bone marrow. Stem Cells (2013) 1.04
Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development. Development (2009) 1.04
Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters. Blood (2011) 1.04
Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling. Blood (2009) 1.01
Systematic assessment in an animal model of the angiogenic potential of different human cell sources for therapeutic revascularization. Stem Cell Res Ther (2012) 1.00
Impaired hematopoiesis in mice lacking the transcription factor Sp3. Blood (2003) 0.99
Comparative study of stromal cell lines derived from embryonic, fetal, and postnatal mouse blood-forming tissues. Exp Hematol (2002) 0.97
Glucocorticoid receptor is required for foetal heart maturation. Hum Mol Genet (2013) 0.95
Analysis and manipulation of hematopoietic progenitor and stem cells from murine embryonic tissues. Curr Protoc Stem Cell Biol (2008) 0.94
Hepatic differentiation of murine embryonic stem cells. Exp Cell Res (2002) 0.94
Interleukin-1-mediated hematopoietic cell regulation in the aorta-gonad-mesonephros region of the mouse embryo. Blood (2008) 0.93
Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6. Eur J Immunol (2009) 0.93
The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway. J Cell Sci (2006) 0.92
Expression of the Ly-6A (Sca-1) lacZ transgene in mouse haematopoietic stem cells and embryos. Br J Haematol (2002) 0.91
Fine-tuning of hematopoietic stem cell homeostasis: novel role for ubiquitin ligase. Genes Dev (2008) 0.91
HOXB4 can enhance the differentiation of embryonic stem cells by modulating the hematopoietic niche. Stem Cells (2012) 0.90
Identification of 2 novel genes developmentally regulated in the mouse aorta-gonad-mesonephros region. Blood (2002) 0.90
Ontogeny and genetics of the hemato/lymphopoietic system. Curr Opin Immunol (2002) 0.89
Bcl-2 expression and apoptosis in the regulation of hematopoietic stem cells. Leuk Lymphoma (2007) 0.89
Hematopoietic stem cell enrichment from the AGM region of the mouse embryo. Methods Mol Med (2005) 0.89
The role of apoptosis in the development of AGM hematopoietic stem cells revealed by Bcl-2 overexpression. Blood (2004) 0.89
Maintenance of HSC by Wnt5a secreting AGM-derived stromal cell line. Exp Hematol (2010) 0.89
Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis. J Cell Sci (2002) 0.88
Aminopeptidase O contains a functional nucleolar localization signal and is implicated in vascular biology. J Cell Biochem (2008) 0.88
A Role for PML in Innate Immunity. Genes Cancer (2011) 0.88
11β-hydroxysteroid dehydrogenase type 1 deficiency in bone marrow-derived cells reduces atherosclerosis. FASEB J (2013) 0.88
A novel transmembrane MSP-containing protein that plays a role in right ventricle development. Genomics (2004) 0.86
Inhibition of the proteasome induces cell cycle arrest and apoptosis in mantle cell lymphoma cells. Br J Haematol (2003) 0.86
Interleukin-1 regulates hematopoietic progenitor and stem cells in the midgestation mouse fetal liver. Haematologica (2009) 0.86
Does nicotine influence cytokine profile and subsequent cell cycling/apoptotic responses in inflammatory bowel disease? Inflamm Bowel Dis (2008) 0.85
Integrin αIIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta. Biol Open (2013) 0.85
Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation. J Biol Chem (2002) 0.84
Ectopic expression of TAL-1 protein in Ly-6E.1-htal-1 transgenic mice induces defects in B- and T-lymphoid differentiation. Blood (2002) 0.84
Cell-cell contact and anatomical compatibility in stromal cell-mediated HSC support during development. Stem Cells (2004) 0.84
The culture of mouse embryonic stem cells and formation of embryoid bodies. Methods Mol Biol (2010) 0.84
The repair and recombination enzyme ERCC1 is not required for immunoglobulin class switching. DNA Repair (Amst) (2003) 0.84
Hypoxia and HIFs in regulating the development of the hematopoietic system. Blood Cells Mol Dis (2013) 0.84
Isolation of early hematopoietic stem cells from murine yolk sac and AGM. J Vis Exp (2008) 0.83
Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells. Haematologica (2012) 0.83
Pure populations of murine macrophages from cultured embryonic stem cells. Application to studies of chemotaxis and apoptotic cell clearance. J Immunol Methods (2012) 0.82
Induction of hematopoietic differentiation of mouse embryonic stem cells by an AGM-derived stromal cell line is not further enhanced by overexpression of HOXB4. Stem Cells Dev (2010) 0.81
Embryonic beginnings of adult hematopoietic stem cells. Haematologica (2005) 0.81
Human embryonic stem cells rapidly take up and then clear exogenous human and animal prions in vitro. J Pathol (2011) 0.80
Expression of a novel homeobox gene Ehox in trophoblast stem cells and pharyngeal pouch endoderm. Dev Dyn (2003) 0.79
Cks1 promotion of S phase entry and proliferation is independent of p27Kip1 suppression. Mol Cell Biol (2012) 0.78
Novel biopolymers to enhance endothelialisation of intra-vascular devices. Adv Healthc Mater (2012) 0.78
Portal venous endothelium in developing human liver contains haematopoietic and epithelial progenitor cells. Exp Cell Res (2010) 0.77
Multipotential hematopoietic progenitor cells from embryos developed in vitro engraft unconditioned W41/W41 neonatal miceB. Haematologica (2005) 0.77
Haematopoietic differentiation is inhibited when Notch activity is enhanced in FLK1(+) mesoderm progenitors. Stem Cell Res (2013) 0.77