1
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Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis.
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Dev Cell
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2002
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4.94
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2
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Identification of psl, a locus encoding a potential exopolysaccharide that is essential for Pseudomonas aeruginosa PAO1 biofilm formation.
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J Bacteriol
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2004
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3.39
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3
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The EPS matrix: the "house of biofilm cells".
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J Bacteriol
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2007
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3.38
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4
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Assembly and development of the Pseudomonas aeruginosa biofilm matrix.
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PLoS Pathog
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2009
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2.85
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5
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Role of polysaccharides in Pseudomonas aeruginosa biofilm development.
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Curr Opin Microbiol
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2007
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2.74
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6
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Analysis of Pseudomonas aeruginosa conditional psl variants reveals roles for the psl polysaccharide in adhesion and maintaining biofilm structure postattachment.
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J Bacteriol
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2006
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2.53
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7
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Understanding the control of Pseudomonas aeruginosa alginate synthesis and the prospects for management of chronic infections in cystic fibrosis.
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Mol Microbiol
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2005
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2.49
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8
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Anaerobic metabolism and quorum sensing by Pseudomonas aeruginosa biofilms in chronically infected cystic fibrosis airways: rethinking antibiotic treatment strategies and drug targets.
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Adv Drug Deliv Rev
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2002
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2.27
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9
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Pseudomonas aeruginosa uses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix.
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Mol Microbiol
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2010
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2.24
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10
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Pseudomonas aeruginosa rugose small-colony variants have adaptations that likely promote persistence in the cystic fibrosis lung.
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J Bacteriol
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2009
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2.22
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11
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The pel polysaccharide can serve a structural and protective role in the biofilm matrix of Pseudomonas aeruginosa.
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PLoS Pathog
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2011
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2.04
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12
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Pseudomonas biofilm matrix composition and niche biology.
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FEMS Microbiol Rev
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2012
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2.00
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13
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Genetic and biochemical analyses of the Pseudomonas aeruginosa Psl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production.
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Mol Microbiol
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2009
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1.91
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14
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The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix.
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Environ Microbiol
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2011
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1.69
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15
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Pseudomonas aeruginosa biofilm matrix polysaccharide Psl is regulated transcriptionally by RpoS and post-transcriptionally by RsmA.
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Mol Microbiol
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2010
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1.66
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16
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The Pseudomonas aeruginosa ribbon-helix-helix DNA-binding protein AlgZ (AmrZ) controls twitching motility and biogenesis of type IV pili.
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J Bacteriol
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2006
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1.63
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17
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Pseudomonas aeruginosa Psl is a galactose- and mannose-rich exopolysaccharide.
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J Bacteriol
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2007
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1.37
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18
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Phosphorylation of the Pseudomonas aeruginosa response regulator AlgR is essential for type IV fimbria-mediated twitching motility.
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J Bacteriol
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2002
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1.37
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19
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Self-produced exopolysaccharide is a signal that stimulates biofilm formation in Pseudomonas aeruginosa.
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Proc Natl Acad Sci U S A
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2012
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1.36
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20
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The alternative sigma factor AlgT represses Pseudomonas aeruginosa flagellum biosynthesis by inhibiting expression of fleQ.
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J Bacteriol
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2005
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1.26
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21
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Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization.
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Cell Microbiol
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2011
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1.25
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22
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The AlgT-dependent transcriptional regulator AmrZ (AlgZ) inhibits flagellum biosynthesis in mucoid, nonmotile Pseudomonas aeruginosa cystic fibrosis isolates.
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J Bacteriol
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2006
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1.18
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23
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Pseudomonas aeruginosa flagellin and alginate elicit very distinct gene expression patterns in airway epithelial cells: implications for cystic fibrosis disease.
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J Immunol
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2004
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1.16
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24
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Role of Pseudomonas aeruginosa dinB-encoded DNA polymerase IV in mutagenesis.
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J Bacteriol
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2006
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1.13
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25
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The roles of biofilm matrix polysaccharide Psl in mucoid Pseudomonas aeruginosa biofilms.
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FEMS Immunol Med Microbiol
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2012
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1.13
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26
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A fusion protein vaccine containing OprF epitope 8, OprI, and type A and B flagellins promotes enhanced clearance of nonmucoid Pseudomonas aeruginosa.
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Infect Immun
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2009
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1.12
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27
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Immunization of young African green monkeys with OprF epitope 8-OprI-type A- and B-flagellin fusion proteins promotes the production of protective antibodies against nonmucoid Pseudomonas aeruginosa.
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Vaccine
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2009
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1.10
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28
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Binding of Pseudomonas aeruginosa AlgZ to sites upstream of the algZ promoter leads to repression of transcription.
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J Bacteriol
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2005
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1.05
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29
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The BvgAS signal transduction system regulates biofilm development in Bordetella.
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J Bacteriol
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2005
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1.05
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30
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Static growth of mucoid Pseudomonas aeruginosa selects for non-mucoid variants that have acquired flagellum-dependent motility.
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Microbiology
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2002
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1.04
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31
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The sigma factor AlgU plays a key role in formation of robust biofilms by nonmucoid Pseudomonas aeruginosa.
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J Bacteriol
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2010
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1.02
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32
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The NtrC family regulator AlgB, which controls alginate biosynthesis in mucoid Pseudomonas aeruginosa, binds directly to the algD promoter.
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J Bacteriol
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2007
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1.01
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33
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A spider web strategy of type IV pili-mediated migration to build a fibre-like Psl polysaccharide matrix in Pseudomonas aeruginosa biofilms.
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Environ Microbiol
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2013
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1.01
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34
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The Pseudomonas aeruginosa exopolysaccharide Psl facilitates surface adherence and NF-kappaB activation in A549 cells.
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MBio
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2010
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0.98
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35
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Control of bacterial biofilms with marine alkaloid derivatives.
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Mol Biosyst
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2008
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0.97
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36
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Synthesis of multiple Pseudomonas aeruginosa biofilm matrix exopolysaccharides is post-transcriptionally regulated.
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Environ Microbiol
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2012
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0.95
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37
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Direct evaluation of Pseudomonas aeruginosa biofilm mediators in a chronic infection model.
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Infect Immun
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2011
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0.94
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38
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The transcription factor AmrZ utilizes multiple DNA binding modes to recognize activator and repressor sequences of Pseudomonas aeruginosa virulence genes.
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PLoS Pathog
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2012
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0.94
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39
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Pseudomonas aeruginosa AlgR regulates type IV pilus biosynthesis by activating transcription of the fimU-pilVWXY1Y2E operon.
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J Bacteriol
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2008
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0.92
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40
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Epistatic roles for Pseudomonas aeruginosa MutS and DinB (DNA Pol IV) in coping with reactive oxygen species-induced DNA damage.
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PLoS One
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2011
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0.91
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41
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AmrZ modulates Pseudomonas aeruginosa biofilm architecture by directly repressing transcription of the psl operon.
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J Bacteriol
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2013
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0.90
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42
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First evidence of sternal wound biofilm following cardiac surgery.
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PLoS One
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2013
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0.89
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43
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Bacterial Extracellular Polysaccharides in Biofilm Formation and Function.
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Microbiol Spectr
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2015
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0.89
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44
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AmrZ beta-sheet residues are essential for DNA binding and transcriptional control of Pseudomonas aeruginosa virulence genes.
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J Bacteriol
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2010
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0.88
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45
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Biofilms and infectious diseases: biology to mathematics and back again.
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FEMS Microbiol Lett
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2011
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0.86
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46
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The exopolysaccharide Psl-eDNA interaction enables the formation of a biofilm skeleton in Pseudomonas aeruginosa.
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Environ Microbiol Rep
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2015
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0.83
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47
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The role of biofilms in airway disease.
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Semin Respir Crit Care Med
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2003
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0.79
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48
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Crystallization of Pseudomonas aeruginosa AmrZ protein: development of a comprehensive method for obtaining and optimization of protein-DNA crystals.
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Acta Crystallogr Sect F Struct Biol Cryst Commun
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2012
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0.78
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