Published in BMC Mol Biol on September 11, 2006
It all comes together at the ends: telomerase structure, function, and biogenesis. Mutat Res (2011) 1.36
A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis. PLoS One (2008) 1.08
Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers. Cancer Res (2008) 1.07
RNAi screen for telomerase reverse transcriptase transcriptional regulators identifies HIF1alpha as critical for telomerase function in murine embryonic stem cells. Proc Natl Acad Sci U S A (2010) 0.96
GAPDH is not regulated in human glioblastoma under hypoxic conditions. BMC Mol Biol (2007) 0.89
Selection strategy and the design of hybrid oligonucleotide primers for RACE-PCR: cloning a family of toxin-like sequences from Agelena orientalis. BMC Mol Biol (2007) 0.89
Medaka tert produces multiple variants with differential expression during differentiation in vitro and in vivo. Int J Biol Sci (2011) 0.87
Identification of novel retroid agents in Danio rerio, Oryzias latipes, Gasterosteus aculeatus and Tetraodon nigroviridis. Evol Bioinform Online (2007) 0.86
Microenvironmental regulation of telomerase isoforms in human embryonic stem cells. Stem Cells Dev (2014) 0.84
Hypoxia turns genotypic female medaka fish into phenotypic males. Ecotoxicology (2014) 0.79
Development of a promising fish model (Oryzias melastigma) for assessing multiple responses to stresses in the marine environment. Biomed Res Int (2014) 0.77
Identification of robust hypoxia biomarker candidates from fin of medaka (Oryzias latipes). Comp Biochem Physiol C Toxicol Pharmacol (2011) 0.77
Effect of different stress factors on some physiological parameters of Nile tilapia (Oreochromis niloticus). Saudi J Biol Sci (2010) 0.75
Telomerase catalytic subunit homologs from fission yeast and human. Science (1997) 12.35
Reverse transcriptase motifs in the catalytic subunit of telomerase. Science (1997) 10.10
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation. Nat Cell Biol (2003) 7.02
Telomere length regulation. Annu Rev Biochem (1996) 6.98
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nat Genet (1997) 6.69
HIF-1alpha induces cell cycle arrest by functionally counteracting Myc. EMBO J (2004) 4.26
Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc Natl Acad Sci U S A (1996) 3.89
Human telomerase and its regulation. Microbiol Mol Biol Rev (2002) 3.11
Hypoxia: from molecular responses to ecosystem responses. Mar Pollut Bull (2002) 2.62
Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene. Cancer Res (1999) 2.32
Hypoxia-induced gene expression profiling in the euryoxic fish Gillichthys mirabilis. Proc Natl Acad Sci U S A (2001) 2.07
Identification of functionally important domains in the N-terminal region of telomerase reverse transcriptase. Mol Cell Biol (2000) 1.83
Hypoxia-inducible factor 1 mediates upregulation of telomerase (hTERT). Mol Cell Biol (2004) 1.65
Aquatic hypoxia is an disrupter and impairs fish reproduction. Environ Sci Technol (2003) 1.51
C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity. Mol Cell Biol (2002) 1.46
Understanding hypoxia-induced gene expression in early development: in vitro and in vivo analysis of hypoxia-inducible factor 1-regulated zebra fish insulin-like growth factor binding protein 1 gene expression. Mol Cell Biol (2006) 1.34
Insulin-like growth factor-binding protein-1 (IGFBP-1) mediates hypoxia-induced embryonic growth and developmental retardation. Proc Natl Acad Sci U S A (2005) 1.34
Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells. Mol Cell Biol (2005) 1.31
The zebrafish as a vertebrate model of functional aging and very gradual senescence. Exp Gerontol (2003) 1.28
Myb binding proteins: regulators and cohorts in transformation. Oncogene (1999) 1.22
c-Myc/Max heterodimers bind cooperatively to the E-box sequences located in the first intron of the rat ornithine decarboxylase (ODC) gene. Nucleic Acids Res (1997) 1.20
The application of histo-cytopathological biomarkers in marine pollution monitoring: a review. Mar Pollut Bull (2004) 1.17
HIF-1-mediated activation of telomerase in cervical cancer cells. Oncogene (2004) 1.16
Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms. Oncogene (2006) 1.14
The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function. J Mol Neurosci (2000) 1.11
Hypoxia up-regulates telomerase activity via mitogen-activated protein kinase signaling in human solid tumor cells. Biochem Biophys Res Commun (1999) 1.01
Telomere length in male germ cells is inversely correlated with telomerase activity. Biol Reprod (2000) 0.98
Telomerase activity in 'immortal' fish. FEBS Lett (1998) 0.97
Telomerase mediates the cell survival-promoting actions of brain-derived neurotrophic factor and secreted amyloid precursor protein in developing hippocampal neurons. J Neurosci (2002) 0.97
Extratelomeric functions of telomerase. Curr Mol Med (2005) 0.97
The chicken telomerase reverse transcriptase (chTERT): molecular and cytogenetic characterization with a comparative analysis. Gene (2004) 0.92
Identification and analyses of the Xenopus TERT gene that encodes the catalytic subunit of telomerase. Gene (2001) 0.91
Cloning and expression of the reverse transcriptase component of pufferfish (Fugu rubripes) telomerase. Gene (2005) 0.87
Telomerase, immortality and cancer. Biotechnol Annu Rev (2000) 0.84
Ageing in amphibians. Gerontology (1994) 0.78
Evolution of new variants of Vibrio cholerae O1. Trends Microbiol (2009) 3.75
Vibrio cholerae O1 hybrid El Tor strains, Asia and Africa. Emerg Infect Dis (2008) 2.53
Characterization of ion channel and transporter mRNA expressions in isolated gill chloride and pavement cells of seawater acclimating eels. Biochem Biophys Res Commun (2006) 1.08
Durable mesenchymal stem cell labelling by using polyhedral superparamagnetic iron oxide nanoparticles. Chemistry (2009) 1.01
Effects of moderate and substantial hypoxia on erythropoietin levels in rainbow trout kidney and spleen. J Exp Biol (2006) 1.00
Isolation, characterization and expression analysis of a hypoxia-responsive glucose transporter gene from the grass carp, Ctenopharyngodon idellus. Eur J Biochem (2003) 0.93
Effect of osmotic shrinkage and hormones on the expression of Na+/H+ exchanger-1, Na+/K+/2Cl- cotransporter and Na+/K+ -ATPase in gill pavement cells of freshwater adapted Japanese eel, Anguilla japonica. J Exp Biol (2007) 0.92
Japanese medaka: a new vertebrate model for studying telomere and telomerase biology. Comp Biochem Physiol C Toxicol Pharmacol (2008) 0.92
Cloning and expression analysis of two distinct HIF-alpha isoforms--gcHIF-1alpha and gcHIF-4alpha--from the hypoxia-tolerant grass carp, Ctenopharyngodon idellus. BMC Mol Biol (2006) 0.92
Multilocus genetic analysis reveals that the Australian strains of Vibrio cholerae O1 are similar to the pre-seventh pandemic strains of the El Tor biotype. J Med Microbiol (2009) 0.90
Identification of a DNA methyltransferase gene carried on a pathogenicity island-like element (VPAI) in Vibrio parahaemolyticus and its prevalence among clinical and environmental isolates. Appl Environ Microbiol (2006) 0.88
Hollow superparamagnetic iron oxide nanoshells as a hydrophobic anticancer drug carrier: intracelluar pH-dependent drug release and enhanced cytotoxicity. Nanoscale (2012) 0.87
Pamidronate, farnesyl transferase, and geranylgeranyl transferase-I inhibitors affects cell proliferation, apoptosis, and OPG/RANKL mRNA expression in stromal cells of giant cell tumor of bone. J Orthop Res (2010) 0.83
Analysis of the 16S-23S rDNA intergenic spacers (IGSs) of marine vibrios for species-specific signature DNA sequences. Mar Pollut Bull (2002) 0.83
Occurrence and fate of pharmaceuticals and personal care products in drinking water in southern China. J Environ Monit (2011) 0.82
The effects of sub-lethal UV-C irradiation on growth and cell integrity of cyanobacteria and green algae. Chemosphere (2009) 0.82
15th International Symposium on Toxicity Assessment : new directions in ecotoxicology and meeting the challenges ahead. Environ Sci Pollut Res Int (2012) 0.81
Characterization of a hypoxia-responsive leptin receptor (omLepR(L)) cDNA from the marine medaka (Oryzias melastigma). Mar Pollut Bull (2007) 0.81
A high-throughput histoarray for quantitative molecular profiling of multiple, uniformly oriented medaka (Oryzias latipes) embryos. Comp Biochem Physiol C Toxicol Pharmacol (2011) 0.80
Temporal changes of ethoxyresorufin-o-deethylase (EROD) activities and lysosome accumulation in intestine of fish on chronic exposure to dietary benzo[a]pyrene: linking erod induction to cytological effects. Environ Toxicol Chem (2006) 0.80
Induction and recovery of morphofunctional changes in the intestine of juvenile carnivorous fish (Epinephelus coioides) upon exposure to foodborne benzo[a]pyrene. Aquat Toxicol (2007) 0.80
The marine medaka Oryzias melastigma--a potential marine fish model for innate immune study. Mar Pollut Bull (2011) 0.80
Identification of differentially expressed genes and quantitative expression of complement genes in the liver of marine medaka Oryzias melastigma challenged with Vibrio parahaemolyticus. Comp Biochem Physiol Part D Genomics Proteomics (2012) 0.80
The initial and subsequent inflammatory events during calcium oxalate lithiasis. Clin Chim Acta (2010) 0.79
Activity of the MEK inhibitor selumetinib (AZD6244; ARRY-142886) in nasopharyngeal cancer cell lines. Invest New Drugs (2012) 0.78
Hydrogen peroxide is not the cause of fish kills associated with Chattonella marina: cytological and physiological evidence. Aquat Toxicol (2005) 0.78
Gender-specific transcriptional profiling of marine medaka (Oryzias melastigma) liver upon BDE-47 exposure. Comp Biochem Physiol Part D Genomics Proteomics (2013) 0.78
Biodegradation and enzymatic responses in the marine diatom Skeletonema costatum upon exposure to 2,4-dichlorophenol. Aquat Toxicol (2002) 0.78
Use of medaka in toxicity testing. Curr Protoc Toxicol (2009) 0.78
Gender-specific modulation of immune system complement gene expression in marine medaka Oryzias melastigma following dietary exposure of BDE-47. Environ Sci Pollut Res Int (2012) 0.78
Evaluation of biomarkers of exposure and effect in juvenile areolated grouper (Epinephelus areolatus) on foodborne exposure to benzo[a]pyrene. Environ Toxicol Chem (2003) 0.78
Toxicity comparison between Chattonella marina and Karenia brevis using marine medaka (Oryzias melastigma): Evidence against the suspected ichthyotoxins of Chattonella marina. Chemosphere (2010) 0.78
The use of muscle burden in rabbitfish Siganus oramin for monitoring polycyclic aromatic hydrocarbons and polychlorinated biphenyls in Victoria Harbour, Hong Kong and potential human health risk. Sci Total Environ (2009) 0.77
Molecular cloning and expression of novel metallothionein (MT) gene in the polychaete Perinereis nuntia exposed to metals. Environ Sci Pollut Res Int (2012) 0.77
Polybrominated diphenylethers (PBDEs) alter larval settlement of marine benthic polychaetes. Environ Sci Technol (2010) 0.77
Time-dependent transcriptional profiles of genes of the hypothalamic-pituitary-gonadal axis in medaka (Oryzias latipes) exposed to fadrozole and 17beta-trenbolone. Environ Toxicol Chem (2008) 0.77
Complete mitochondrial genome of the marine medaka Oryzias melastigma (Beloniformes, Adrianichthyidae). Mitochondrial DNA (2012) 0.77
Evaluation of biomarker potential of cytochrome P450 1A (CYP1A) gene in the marine medaka, Oryzias melastigma exposed to water-accommodated fractions (WAFs) of Iranian crude oil. Comp Biochem Physiol C Toxicol Pharmacol (2012) 0.76
Measuring and monitoring persistent organic pollutants in the context of risk assessment. Mar Pollut Bull (2008) 0.76
Susceptibility of fish to Chattonella marina is determined by its tolerance to hypoxia. Mar Pollut Bull (2011) 0.76
Advanced fluorescence in situ hybridization to localize and quantify gene expression in Japanese medaka (Oryzias latipes) exposed to endocrine-disrupting compounds. Environ Toxicol Chem (2009) 0.76
Cloning and expression analysis of the pcbAB-pcbC beta-lactam genes in the marine fungus Kallichroma tethys. Appl Environ Microbiol (2003) 0.76
Hepatic proteomic responses in marine medaka (Oryzias melastigma) chronically exposed to antifouling compound butenolide [5-octylfuran-2(5H)-one] or 4,5-dichloro-2-N-octyl-4-isothiazolin-3-one (DCOIT). Environ Sci Technol (2015) 0.76
Chronic Exposure of Marine Medaka (Oryzias melastigma) to 4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) Reveals Its Mechanism of Action in Endocrine Disruption via the Hypothalamus-Pituitary-Gonadal-Liver (HPGL) Axis. Environ Sci Technol (2016) 0.75
Endocrine Disruption throughout the Hypothalamus-Pituitary-Gonadal-Liver (HPGL) Axis in Marine Medaka (Oryzias melastigma) Chronically Exposed to the Antifouling and Chemopreventive Agent, 3,3'-Diindolylmethane (DIM). Chem Res Toxicol (2016) 0.75
Functional characterization of two CITED3 homologs (gcCITED3a and gcCITED3b) in the hypoxia-tolerant grass carp, Ctenopharyngodon idellus. BMC Mol Biol (2009) 0.75
Effect of membrane properties on the performance of a hybrid GAC and ultrafiltration process for water treatment. Environ Technol (2012) 0.75
Investigation of microbial safety of a full-scale ozonation and biological activated carbon process under high humidity and temperature conditions. Water Sci Technol (2011) 0.75
Physiological and cytological responses of the marine diatom Skeletonema costatum to 2,4-dichlorophenol. Aquat Toxicol (2002) 0.75
Selective resorption in nutritive phagocytes of the sea urchin Anthocidaris crassispina. Zygote (2004) 0.75
UV-B damages eyes of barnacle larvae and impairs their photoresponses and settlement success. Environ Sci Technol (2003) 0.75
The ichthyotoxic alga Chattonella marina induces Na+, K+ -ATPase, and CFTR proteins expression in fish gill chloride cells in vivo. Biochem Biophys Res Commun (2006) 0.75
Ethoxyresorufin-O-deethylase enzyme activities and accumulation of secondary/tertiary lysosomes in rabbitfish Siganus oramin as biomarkers for xenobiotic exposures. Sci Total Environ (2010) 0.75
Unravelling the pathway of respiratory toxicity in goldlined seabream (Rhabdosargus sarba) induced by the harmful alga Chattonella marina. Aquat Toxicol (2011) 0.75
Osmotic distress: a probable cause of fish kills on exposure to a subbloom concentration of the toxic alga Chattonella marina. Environ Toxicol Chem (2004) 0.75
The involvement of N-G,N-G-dimethyarginine dimethylhydrolase 1 in the proliferative effect of Astragali radix on cardiac cells. J Ethnopharmacol (2010) 0.75