Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system.

PubWeight™: 2.65‹?› | Rank: Top 1%

🔗 View Article (PMC 2116212)

Published in J Cell Biol on August 01, 1990

Authors

Y Sato1, R Tsuboi, R Lyons, H Moses, D B Rifkin

Author Affiliations

1: Department of Cell Biology, New York University Medical Center, New York.

Articles citing this

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev (2000) 8.24

PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate. J Cell Biol (1998) 5.21

Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction. J Clin Invest (2003) 4.58

Metformin prevents alcohol-induced liver injury in the mouse: Critical role of plasminogen activator inhibitor-1. Gastroenterology (2006) 3.53

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J Cell Biol (1991) 3.38

Absence of integrin-mediated TGFbeta1 activation in vivo recapitulates the phenotype of TGFbeta1-null mice. J Cell Biol (2007) 2.94

Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism. J Cell Biol (1993) 2.81

Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. EMBO J (1992) 2.65

Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. Proc Natl Acad Sci U S A (1991) 2.27

Latent transforming growth factor-beta binding protein domains involved in activation and transglutaminase-dependent cross-linking of latent transforming growth factor-beta. J Cell Biol (1997) 1.98

VE-statin, an endothelial repressor of smooth muscle cell migration. EMBO J (2003) 1.84

A novel complex between the p65 subunit of NF-kappa B and c-Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene. EMBO J (1992) 1.81

Endothelial production of C-type natriuretic peptide and its marked augmentation by transforming growth factor-beta. Possible existence of "vascular natriuretic peptide system". J Clin Invest (1992) 1.78

Role of the latent TGF-beta binding protein in the activation of latent TGF-beta by co-cultures of endothelial and smooth muscle cells. J Cell Biol (1993) 1.71

Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cells. J Cell Biol (1993) 1.66

The integrin alphavbeta3 is a receptor for the latency-associated peptides of transforming growth factors beta1 and beta3. Biochem J (2003) 1.58

Mechanism and its regulation of tumor-induced angiogenesis. World J Gastroenterol (2003) 1.55

Basic fibroblast growth factor-induced activation of latent transforming growth factor beta in endothelial cells: regulation of plasminogen activator activity. J Cell Biol (1992) 1.51

Mathematical modeling of tumor-induced angiogenesis. J Math Biol (2004) 1.51

uPAR promotes formation of the p130Cas-Crk complex to activate Rac through DOCK180. J Cell Biol (2008) 1.43

One systemic administration of transforming growth factor-beta 1 reverses age- or glucocorticoid-impaired wound healing. J Clin Invest (1993) 1.42

Lens-specific expression of transforming growth factor beta1 in transgenic mice causes anterior subcapsular cataracts. J Clin Invest (1998) 1.40

Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am J Pathol (2004) 1.39

Review of the activation of TGF-beta in immunity. J Leukoc Biol (2008) 1.35

Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor beta 1. J Cell Biol (1992) 1.30

The extracellular regulation of growth factor action. Mol Biol Cell (1992) 1.25

Fibrin accumulation plays a critical role in the sensitization to lipopolysaccharide-induced liver injury caused by ethanol in mice. Hepatology (2009) 1.23

The pericyte: cellular regulator of microvascular blood flow. Microvasc Res (2009) 1.19

Decreased type II/type I TGF-beta receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-beta1. J Clin Invest (1995) 1.18

Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways. J Biol Chem (2007) 1.17

Role of reactive oxygen and nitrogen species in the vascular responses to inflammation. Free Radic Biol Med (2011) 1.17

siRNA-mediated simultaneous downregulation of uPA and its receptor inhibits angiogenesis and invasiveness triggering apoptosis in breast cancer cells. Int J Oncol (2006) 1.16

Immunohistochemical localization of transforming growth factor-beta 1 in rats with experimental silicosis, alveolar type II hyperplasia, and lung cancer. Am J Pathol (1993) 1.14

A critical role for transforming growth factor-beta in donor transfusion-induced allograft tolerance. J Clin Invest (1998) 1.13

Overexpression of bone morphogenetic protein-6 (BMP-6) in the epidermis of transgenic mice: inhibition or stimulation of proliferation depending on the pattern of transgene expression and formation of psoriatic lesions. J Cell Biol (1996) 1.13

Dermatopontin interacts with transforming growth factor beta and enhances its biological activity. Biochem J (1999) 1.12

Coordinated induction of extracellular proteolysis systems during experimental autoimmune encephalomyelitis in mice. Am J Pathol (2001) 1.12

The role of up-regulated serine proteases and matrix metalloproteinases in the pathogenesis of a murine model of colitis. Am J Pathol (2000) 1.12

The mechanism for the activation of latent TGF-beta during co-culture of endothelial cells and smooth muscle cells: cell-type specific targeting of latent TGF-beta to smooth muscle cells. J Cell Biol (1993) 1.10

Diverse roles of the vasculature within the neural stem cell niche. Regen Med (2009) 1.09

Active transforming growth factor-beta in wound repair: determination using a new assay. Am J Pathol (1999) 1.08

TGF-beta1 induces bone marrow reticulin fibrosis in hairy cell leukemia. J Clin Invest (2004) 1.08

Lipoprotein (a) inhibits the generation of transforming growth factor beta: an endogenous inhibitor of smooth muscle cell migration. J Cell Biol (1991) 1.07

Independent regulation of transforming growth factor-beta1 transcription and translation by glucose and platelet-derived growth factor. Am J Pathol (2002) 1.03

Transforming growth factor beta1 induction of vascular endothelial growth factor receptor 1: mechanism of pericyte-induced vascular survival in vivo. Proc Natl Acad Sci U S A (2003) 1.03

Interaction of monocytes with cocultures of human aortic wall cells involves interleukins 1 and 6 with marked increases in connexin43 message. J Clin Invest (1991) 1.02

The crystal structure of CREG, a secreted glycoprotein involved in cellular growth and differentiation. Proc Natl Acad Sci U S A (2005) 1.02

Pericyte Rho GTPase mediates both pericyte contractile phenotype and capillary endothelial growth state. Am J Pathol (2007) 1.00

New role of plasminogen activator inhibitor-1 in alcohol-induced liver injury. J Gastroenterol Hepatol (2008) 1.00

The hemostatic system and angiogenesis in malignancy. Neoplasia (2001) 0.99

Urokinase-receptor biosynthesis, mRNA level and gene transcription are increased by transforming growth factor beta 1 in human A549 lung carcinoma cells. EMBO J (1991) 0.99

Angiogenic growth factors in neural embryogenesis and neoplasia. Am J Pathol (1995) 0.96

Alcoholic liver disease and the potential role of plasminogen activator inhibitor-1 and fibrin metabolism. Exp Biol Med (Maywood) (2012) 0.96

Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure. Am J Respir Cell Mol Biol (2006) 0.96

Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6). J Cell Biol (1993) 0.96

TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy. J Exp Med (2013) 0.96

Biological Significance of Local TGF-β Activation in Liver Diseases. Front Physiol (2012) 0.95

Proteasomal regulation of pulmonary fibrosis. Proc Am Thorac Soc (2010) 0.95

Brain pericytes: emerging concepts and functional roles in brain homeostasis. Cell Mol Neurobiol (2011) 0.91

Acute alcohol-induced liver injury. Front Physiol (2012) 0.90

Integrin alpha3beta1 potentiates TGFbeta-mediated induction of MMP-9 in immortalized keratinocytes. J Invest Dermatol (2007) 0.90

The plasmin cascade and matrix metalloproteinases in non-small cell lung cancer. Thorax (1999) 0.90

Spontaneous production of transforming growth factor-beta 2 by primary cultures of bronchial epithelial cells. Effects on cell behavior in vitro. J Clin Invest (1992) 0.88

Human cytomegalovirus induces TGF-β1 activation in renal tubular epithelial cells after epithelial-to-mesenchymal transition. PLoS Pathog (2010) 0.87

Design of growth factor sequestering biomaterials. Chem Commun (Camb) (2014) 0.87

Induction of endogenous genes following infection of human endothelial cells with an E1(-) E4(+) adenovirus gene transfer vector. J Virol (1999) 0.85

Insulin acts through FOXO3a to activate transcription of plasminogen activator inhibitor type 1. Mol Endocrinol (2009) 0.85

TGF-beta1 regulates human brain pericyte inflammatory processes involved in neurovasculature function. J Neuroinflammation (2016) 0.85

Cell-cell signaling between adult rat ventricular myocytes and cardiac microvascular endothelial cells in heterotypic primary culture. J Clin Invest (1993) 0.84

Transcriptional activation of endothelial cells by TGFβ coincides with acute microvascular plasticity following focal spinal cord ischaemia/reperfusion injury. ASN Neuro (2009) 0.84

The role of TGFβ1 and LRG1 in cardiac remodelling and heart failure. Biophys Rev (2015) 0.83

Transforming growth factor beta 2 in labial salivary glands in Sjögren's syndrome. Ann Rheum Dis (1995) 0.83

TGF-β Small Molecule Inhibitor SB431542 Reduces Rotator Cuff Muscle Fibrosis and Fatty Infiltration By Promoting Fibro/Adipogenic Progenitor Apoptosis. PLoS One (2016) 0.81

Tamoxifen decreases the rate of proliferation of rat vascular smooth-muscle cells in culture by inducing production of transforming growth factor beta. Biochem J (1993) 0.80

Activation of human platelet-derived latent transforming growth factor-beta 1 by human glioblastoma cells. Comparison with proteolytic and glycosidic enzymes. Biochem J (1991) 0.80

Plasminogen activators and inhibitor type 1 in neoplastic colonic tissue from patients with familial adenomatous polyposis. Br J Cancer (1995) 0.78

Transforming growth factor-Beta and urokinase-type plasminogen activator: dangerous partners in tumorigenesis-implications in skin cancer. ISRN Dermatol (2013) 0.77

Lipoprotein(a): searching for a function. Trans Am Clin Climatol Assoc (1996) 0.75

Articles cited by this

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. Proc Natl Acad Sci U S A (1980) 109.70

Efficeint transcription of RNA into DNA by avian sarcoma virus polymerase. Biochim Biophys Acta (1976) 12.73

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem (1986) 10.00

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization. J Biol Chem (1983) 9.32

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production. Proc Natl Acad Sci U S A (1987) 6.43

Growth inhibitor from BSC-1 cells closely related to platelet type beta transforming growth factor. Science (1984) 5.20

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture. J Cell Biol (1989) 4.57

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J (1987) 4.56

Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium. J Cell Biol (1988) 4.34

Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization. J Biol Chem (1988) 3.98

Latent transforming growth factor-beta from human platelets. A high molecular weight complex containing precursor sequences. J Biol Chem (1988) 3.91

Mechanism of activation of latent recombinant transforming growth factor beta 1 by plasmin. J Cell Biol (1990) 3.81

Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells. J Cell Biol (1987) 3.72

The murine transforming growth factor-beta precursor. J Biol Chem (1986) 3.67

An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes. Proc Natl Acad Sci U S A (1989) 3.65

A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells. Nature (1983) 3.56

Purification and initial characterization of a type beta transforming growth factor from human placenta. Proc Natl Acad Sci U S A (1983) 3.52

Purification and properties of a type beta transforming growth factor from bovine kidney. Biochemistry (1983) 3.49

Normal embryo fibroblasts release transforming growth factors in a latent form. J Cell Physiol (1984) 2.76

Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis. J Cell Biol (1988) 2.69

Inhibition of endothelial regeneration by type-beta transforming growth factor from platelets. Science (1986) 2.67

The effect of transforming growth factor-beta on cell proliferation and collagen formation by lung fibroblasts. J Biol Chem (1987) 2.64

Enhanced production and extracellular deposition of the endothelial-type plasminogen activator inhibitor in cultured human lung fibroblasts by transforming growth factor-beta. J Cell Biol (1986) 2.44

Endothelial cells produce a latent inhibitor of plasminogen activators that can be activated by denaturants. J Biol Chem (1985) 2.23

Transforming growth factor beta is a bifunctional regulator of replication and collagen synthesis in osteoblast-enriched cell cultures from fetal rat bone. J Biol Chem (1987) 2.17

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells. J Cell Biol (1987) 2.04

Osteoblasts synthesize and respond to transforming growth factor-type beta (TGF-beta) in vitro. J Cell Biol (1987) 2.01

Regulation of type 1 plasminogen activator inhibitor gene expression in cultured bovine aortic endothelial cells. Induction by transforming growth factor-beta, lipopolysaccharide, and tumor necrosis factor-alpha. J Biol Chem (1989) 1.92

Beta-transforming growth factor is stored in human blood platelets as a latent high molecular weight complex. Biochem Biophys Res Commun (1986) 1.90

Transforming growth factor-beta inhibits endothelial cell proliferation. Biochem Biophys Res Commun (1986) 1.86

Transforming growth factor-beta-induced growth inhibition and cellular hypertrophy in cultured vascular smooth muscle cells. J Cell Biol (1988) 1.73

Comparison of intra- and extracellular transforming growth factors from nontransformed and chemically transformed mouse embryo cells. Cancer Res (1983) 1.66

Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis. Cell Regul (1989) 1.61

Immunodetection and modulation of cellular growth with antibodies against native transforming growth factor-beta 1. Cancer Res (1987) 1.59

Recombinant TGF-beta 1 is synthesized as a two-component latent complex that shares some structural features with the native platelet latent TGF-beta 1 complex. Growth Factors (1989) 1.51

Transforming growth factor-beta 2: cDNA cloning and sequence analysis. DNA (1988) 1.43

Transforming growth factor beta alters plasminogen activator activity in human skin fibroblasts. Exp Cell Res (1986) 1.32

Environment-dependent growth inhibition of human epidermal keratinocytes by recombinant human transforming growth factor-beta. J Cell Physiol (1989) 0.98

Articles by these authors

The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell (1999) 11.59

An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal Biochem (1994) 6.31

Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. Cell (1992) 5.87

An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses. J Exp Med (1973) 5.53

An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses. J Exp Med (1973) 4.99

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture. J Cell Biol (1989) 4.57

Biology and biochemistry of proteinases in tumor invasion. Physiol Rev (1993) 4.17

Ending smoking at the Johns Hopkins Medical Institutions. An evaluation of smoking prevalence and indoor air pollution. JAMA (1990) 3.78

Biological roles of fibroblast growth factor-2. Endocr Rev (1997) 3.57

Tumor invasion through the human amniotic membrane: requirement for a proteinase cascade. Cell (1986) 3.42

Cell-associated plasminogen activation: regulation and physiological functions. Annu Rev Cell Biol (1988) 3.16

Fibroblast growth factor-2 (FGF-2) induces vascular endothelial growth factor (VEGF) expression in the endothelial cells of forming capillaries: an autocrine mechanism contributing to angiogenesis. J Cell Biol (1998) 3.12

Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation. J Cell Biol (1988) 2.84

Latent transforming growth factor-beta: structural features and mechanisms of activation. Kidney Int (1997) 2.82

Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis. J Cell Biol (1988) 2.69

Purification of a factor from human placenta that stimulates capillary endothelial cell protease production, DNA synthesis, and migration. Proc Natl Acad Sci U S A (1986) 2.62

Presentations and outcomes of neurosarcoidosis: a study of 54 cases. QJM (2009) 2.49

Release of basic fibroblast growth factor-heparan sulfate complexes from endothelial cells by plasminogen activator-mediated proteolytic activity. J Cell Biol (1990) 2.33

Plasminogen activator and collagenase production by cultured capillary endothelial cells. J Cell Biol (1982) 2.33

Cellular activation of latent transforming growth factor beta requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. Proc Natl Acad Sci U S A (1991) 2.27

Interactions between growth factors and integrins: latent forms of transforming growth factor-beta are ligands for the integrin alphavbeta1. Mol Biol Cell (1998) 2.26

Investigation of potential HIV transmission to the patients of an HIV-infected surgeon. JAMA (1993) 2.17

Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex. J Cell Physiol (1992) 2.08

In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases. J Cell Biol (1989) 2.05

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells. J Cell Biol (1987) 2.04

Latent transforming growth factor-beta binding protein domains involved in activation and transglutaminase-dependent cross-linking of latent transforming growth factor-beta. J Cell Biol (1997) 1.98

Purification from a human hepatoma cell line of a basic fibroblast growth factor-like molecule that stimulates capillary endothelial cell plasminogen activator production, DNA synthesis, and migration. Mol Cell Biol (1986) 1.94

TGF-beta latency: biological significance and mechanisms of activation. Stem Cells (1997) 1.91

Both normal and tumor cells produce basic fibroblast growth factor. J Cell Physiol (1986) 1.91

Transformation of rat embryo fibroblasts by cloned polyoma virus DNA fragments containing only part of the early region. Proc Natl Acad Sci U S A (1980) 1.89

Properties of plasminogen activators formed by neoplastic human cell cultures. J Exp Med (1974) 1.88

Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis. Biochim Biophys Acta (1988) 1.82

Recombinant basic fibroblast growth factor stimulates wound healing in healing-impaired db/db mice. J Exp Med (1990) 1.80

Active and latent forms of transforming growth factor beta activity in synovial effusions. J Exp Med (1989) 1.77

Nuclear and cytoplasmic localization of different basic fibroblast growth factor species. J Cell Physiol (1990) 1.75

Role of the latent TGF-beta binding protein in the activation of latent TGF-beta by co-cultures of endothelial and smooth muscle cells. J Cell Biol (1993) 1.71

Isolation and characterization of proteinase from Candida albicans: substrate specificity. J Invest Dermatol (1984) 1.70

Processing, secretion, and biological properties of a novel growth factor of the fibroblast growth factor family with oncogenic potential. Mol Cell Biol (1988) 1.69

A form of human basic fibroblast growth factor with an extended amino terminus. Biochem Biophys Res Commun (1987) 1.69

Proteolytically derived fragments of human plasma fibronectin and their localization within the intact molecule. J Biol Chem (1980) 1.68

Requirement for transglutaminase in the activation of latent transforming growth factor-beta in bovine endothelial cells. J Cell Biol (1993) 1.66

Immunohistochemical localization of basic fibroblast growth factor in astrocytomas. Cancer Res (1990) 1.59

Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding. J Biol Chem (1994) 1.58

A specific labeling procedure for proteins on the outer surface of membranes. J Biol Chem (1972) 1.55

Nonketotic hyperglycemia appearing as choreoathetosis or ballism. Arch Intern Med (1982) 1.54

Basic fibroblast growth factor released by single, isolated cells stimulates their migration in an autocrine manner. Proc Natl Acad Sci U S A (1991) 1.52

Characterization of latent TGF-beta activation by murine peritoneal macrophages. J Immunol (1995) 1.52

Basic fibroblast growth factor-induced activation of latent transforming growth factor beta in endothelial cells: regulation of plasminogen activator activity. J Cell Biol (1992) 1.51

Phospholipid composition of Rous sarcoma virus, host cell membranes and other enveloped RNA viruses. Virology (1971) 1.49

Monospecific antibodies implicate basic fibroblast growth factor in normal wound repair. Lab Invest (1989) 1.48

Tumor promoters induce changes in the chick embryo fibroblast cytoskeleton. Cell (1979) 1.47

Hepatocyte growth factor (HGF) activator expressed in hair follicles is involved in in vitro HGF-dependent hair follicle elongation. J Dermatol Sci (2001) 1.46

Requirement for the large T and small T proteins of SV40 in the maintenance of the transformed state. Cold Spring Harb Symp Quant Biol (1980) 1.43

Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor. J Cell Biol (1990) 1.42

Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro. Proc Natl Acad Sci U S A (1983) 1.42

Plasminogen activators and matrix metalloproteinases in angiogenesis. Enzyme Protein (1996) 1.42

Role of extracellular matrix in the action of basic fibroblast growth factor: matrix as a source of growth factor for long-term stimulation of plasminogen activator production and DNA synthesis. J Cell Physiol (1989) 1.42

Expression of tissue factor procoagulant activity: regulation by cytosolic calcium. Proc Natl Acad Sci U S A (1990) 1.42

Identification and characterization of an eight-cysteine repeat of the latent transforming growth factor-beta binding protein-1 that mediates bonding to the latent transforming growth factor-beta1. J Biol Chem (1996) 1.40

Mr 25,000 heparin-binding protein from guinea pig brain is a high molecular weight form of basic fibroblast growth factor. Proc Natl Acad Sci U S A (1987) 1.39

Early mutants of polyoma virus (dl8 and dl23) with altered transformation properties: is polyoma virus middle T antigen a transforming gene product? Cold Spring Harb Symp Quant Biol (1980) 1.39

A long-term survey of rotavirus infection in Japanese children with acute gastroenteritis. J Infect Dis (1978) 1.39

Molecular analysis of Malassezia microflora on the skin of atopic dermatitis patients and healthy subjects. J Clin Microbiol (2001) 1.38

Correlation of cell migration, cell invasion, receptor number, proteinase production, and basic fibroblast growth factor levels in endothelial cells. J Cell Biol (1990) 1.37

Transformation of primary hamster brain cells with JC virus and its DNA. J Virol (1980) 1.36

Tetradecanoyl phorbol acetate stimulates latent collagenase production by cultured human endothelial cells. Cell (1980) 1.35

The importance of comorbidity in HIV-infected patients over 55: a retrospective case-control study. Am J Med (1996) 1.34

In vitro neurite extension by granule neurons is dependent upon astroglial-derived fibroblast growth factor. Dev Biol (1988) 1.32

Requirement for receptor-bound urokinase in plasmin-dependent cellular conversion of latent TGF-beta to TGF-beta. J Cell Physiol (1994) 1.32

FGF suppresses apoptosis and induces differentiation of fibre cells in the mouse lens. Development (1995) 1.31

Basic fibroblast growth factor modulates integrin expression in microvascular endothelial cells. Mol Biol Cell (1993) 1.31

Cellular glycosylphosphatidylinositol-specific phospholipase D regulates urokinase receptor shedding and cell surface expression. J Cell Physiol (1999) 1.30

Interaction of heparin with human basic fibroblast growth factor: protection of the angiogenic protein from proteolytic degradation by a glycosaminoglycan. J Cell Physiol (1989) 1.30

Differential modulation of cell phenotype by different molecular weight forms of basic fibroblast growth factor: possible intracellular signaling by the high molecular weight forms. J Cell Biol (1995) 1.30

High-affinity RNA ligands to basic fibroblast growth factor inhibit receptor binding. Proc Natl Acad Sci U S A (1993) 1.29

Selective lysis of cells transformed by Rous Sarcoma virus. Virology (1971) 1.29

The NH2-terminal extension of high molecular weight bFGF is a nuclear targeting signal. J Cell Physiol (1991) 1.29

Activation of latent transforming growth factor beta. Adv Pharmacol (1993) 1.26

The extracellular regulation of growth factor action. Mol Biol Cell (1992) 1.25

The organization of the proteins of vesicular stomatitis virions: labeling with pyridoxal phosphate. Virology (1975) 1.23

Extracellular microfibrils in development and disease. Cell Mol Life Sci (2007) 1.21

Ganciclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation? Blood (1994) 1.20

Basic fibroblast growth factor expression in human bone marrow and peripheral blood cells. Blood (1993) 1.19

Behavioural risk factors among young adults in small areas with high mortality versus those in low-mortality areas. Int J Epidemiol (1991) 1.18

Levodopa-induced psychosis: a kindling phenomenon. Am J Psychiatry (1978) 1.17

Diltiazem reduces retinal neovascularization in a mouse model of oxygen induced retinopathy. Curr Eye Res (1999) 1.14

The latent transforming growth factor-beta-binding protein-1 promotes in vitro differentiation of embryonic stem cells into endothelium. Mol Biol Cell (2000) 1.14

Transforming growth factor-beta 1 regulates axon/Schwann cell interactions. J Cell Biol (1995) 1.14

Urokinase-type plasminogen activator mediates basic fibroblast growth factor-induced bovine endothelial cell migration independent of its proteolytic activity. J Cell Physiol (1992) 1.13

Phospholipase C release of basic fibroblast growth factor from human bone marrow cultures as a biologically active complex with a phosphatidylinositol-anchored heparan sulfate proteoglycan. J Cell Biol (1991) 1.13

Postinfectious leukoencephalitis complicating Mycoplasma pneumoniae infection. Arch Neurol (1983) 1.12

Methylation of high molecular weight fibroblast growth factor-2 determines post-translational increases in molecular weight and affects its intracellular distribution. Mol Biol Cell (1996) 1.12

Extracellular matrix regulation of growth factor and protease activity. Curr Opin Cell Biol (1991) 1.12

Production of plasminogen activator by established cell lines of mouse origin. J Cell Biol (1977) 1.11

Studies of Rous sarcoma virus. Effects of nucleoside analogues on virus synthesis. J Biol Chem (1973) 1.11

Sexual Pavlovian conditioned approach behavior in male Japanese quail (Coturnix coturnix japonica). J Comp Psychol (1986) 1.11

Human rotavirus infection in infants and young children with intussusception. J Med Virol (1978) 1.10

Bone defects in latent TGF-beta binding protein (Ltbp)-3 null mice; a role for Ltbp in TGF-beta presentation. J Endocrinol (2002) 1.10