Bernard Weisblum

Author PubWeight™ 35.72‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mimicry of antimicrobial host-defense peptides by random copolymers. J Am Chem Soc 2007 2.12
2 Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides. J Am Chem Soc 2002 1.66
3 Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides. J Am Chem Soc 2007 1.40
4 Regulation of iron transport in Streptococcus pneumoniae by RitR, an orphan response regulator. J Bacteriol 2004 1.34
5 Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency. J Am Chem Soc 2002 1.27
6 Structure-activity relationships among random nylon-3 copolymers that mimic antibacterial host-defense peptides. J Am Chem Soc 2009 1.26
7 Antifungal activity from 14-helical beta-peptides. J Am Chem Soc 2006 1.21
8 Phosphorylation of yellow fever virus NS5 alters methyltransferase activity. Virology 2008 1.13
9 Biocidal activity of polystyrenes that are cationic by virtue of protonation. Org Lett 2004 1.10
10 Electrostatic versus steric effects in peptidomimicry: synthesis and secondary structure analysis of gramicidin S analogues with (E)-alkene peptide isosteres. J Am Chem Soc 2005 1.10
11 Design of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues. Biochemistry 2002 1.10
12 Phosphorylation of the RitR DNA-binding domain by a Ser-Thr phosphokinase: implications for global gene regulation in the streptococci. Mol Microbiol 2008 1.04
13 Unexpected relationships between structure and function in alpha,beta-peptides: antimicrobial foldamers with heterogeneous backbones. J Am Chem Soc 2004 1.03
14 Nylon-3 polymers with selective antifungal activity. J Am Chem Soc 2013 0.91
15 Tuning the biological activity profile of antibacterial polymers via subunit substitution pattern. J Am Chem Soc 2014 0.90
16 Trisubstituted (E)-alkene dipeptide isosteres as beta-turn promoters in the gramicidin S cyclodecapeptide scaffold. Org Lett 2006 0.89
17 Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: evidence of a limit on antimicrobial activity. J Am Chem Soc 2005 0.89
18 Structure-activity relationships among antifungal nylon-3 polymers: identification of materials active against drug-resistant strains of Candida albicans. J Am Chem Soc 2014 0.89
19 Tolerance of acyclic residues in the beta-peptide 12-helix: access to diverse side-chain arrays for biological applications. J Am Chem Soc 2002 0.89
20 C-terminal functionalization of nylon-3 polymers: effects of C-terminal groups on antibacterial and hemolytic activities. Biomacromolecules 2011 0.87
21 Ternary nylon-3 copolymers as host-defense peptide mimics: beyond hydrophobic and cationic subunits. J Am Chem Soc 2014 0.85
22 Synthetic polymers active against Clostridium difficile vegetative cell growth and spore outgrowth. J Am Chem Soc 2014 0.84
23 Screen for inducers of autolysis in Bacillus subtilis. Antimicrob Agents Chemother 2010 0.83
24 Differential assay for high-throughput screening of antibacterial compounds. J Biomol Screen 2007 0.83
25 Functionally Diverse Nylon-3 Copolymers from Readily Accessible β-Lactams. ACS Macro Lett 2012 0.83
26 Hydrophobic core repacking in a coiled-coil dimer via phage display: insights into plasticity and specificity at a protein-protein interface. J Am Chem Soc 2004 0.81
27 Screen for agents that induce autolysis in Bacillus subtilis. Antimicrob Agents Chemother 2012 0.81
28 Improved small-molecule macroarray platform for the rapid synthesis and discovery of antibacterial chalcones. ACS Comb Sci 2011 0.81
29 Roles of salt and conformation in the biological and physicochemical behavior of protegrin-1 and designed analogues: correlation of antimicrobial, hemolytic, and lipid bilayer-perturbing activities. Biochemistry 2006 0.81
30 Nylon-3 polymers active against drug-resistant Candida albicans biofilms. J Am Chem Soc 2015 0.81
31 Affinity adsorbent based on combinatorial phage display peptides that bind alpha-cobratoxin. J Chromatogr B Analyt Technol Biomed Life Sci 2004 0.81
32 Interplay among subunit identity, subunit proportion, chain length, and stereochemistry in the activity profile of sequence-random peptide mixtures. J Am Chem Soc 2013 0.80
33 Phosphorylation of the Streptococcus pneumoniae cell wall biosynthesis enzyme MurC by a eukaryotic-like Ser/Thr kinase. FEMS Microbiol Lett 2013 0.79
34 West Nile virus methyltransferase domain interacts with protein kinase G. Virol J 2013 0.79
35 Bacterial 2-component signal transduction systems: a fluorescence polarization screen for response regulator-protein binding. J Biomol Screen 2005 0.76
36 Screening for compounds that affect the interaction between bacterial two-component signal transduction response regulator protein and cognate promoter DNA. Methods Mol Med 2008 0.75