Published in J Neural Transm Suppl on January 01, 2006
The PINK1/Parkin pathway regulates mitochondrial morphology. Proc Natl Acad Sci U S A (2008) 7.41
Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity. Nat Genet (2009) 3.06
Ubiquitin-like protein conjugation and the ubiquitin-proteasome system as drug targets. Nat Rev Drug Discov (2010) 2.90
Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF-kappaB signaling. Hum Mol Genet (2009) 2.10
Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis. Biochim Biophys Acta (2008) 1.35
The role of glucocerebrosidase mutations in Parkinson disease and Lewy body disorders. Curr Neurol Neurosci Rep (2010) 1.28
Mitochondria, calcium and cell death: a deadly triad in neurodegeneration. Biochim Biophys Acta (2009) 1.27
Mitochondrial dysfunction and oxidative stress in Parkinson's disease. Prog Neurobiol (2013) 1.20
Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss. Nat Neurosci (2013) 1.18
E3 ubiquitin ligases in ErbB receptor quantity control. Semin Cell Dev Biol (2010) 0.96
Parkin plays a role in sporadic Parkinson's disease. Neurodegener Dis (2013) 0.93
Parkin, A Top Level Manager in the Cell's Sanitation Department. Open Biochem J (2011) 0.89
Mitochondrial alterations by PARKIN in dopaminergic neurons using PARK2 patient-specific and PARK2 knockout isogenic iPSC lines. Stem Cell Reports (2015) 0.89
Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration. Proc Natl Acad Sci U S A (2015) 0.87
PINK1 as a molecular checkpoint in the maintenance of mitochondrial function and integrity. Mol Cells (2012) 0.87
Effects of acute dieldrin exposure on neurotransmitters and global gene transcription in largemouth bass (Micropterus salmoides) hypothalamus. Neurotoxicology (2010) 0.87
Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases. Neurobiol Dis (2015) 0.82
Biological targets for isatin and its analogues: Implications for therapy. Biologics (2007) 0.82
Drug Targeting of alpha-Synuclein Oligomerization in Synucleinopathies. Perspect Medicin Chem (2008) 0.80
Mutation in E1, the ubiquitin activating enzyme, reduces Drosophila lifespan and results in motor impairment. PLoS One (2013) 0.80
Deletion of a novel F-box protein, MUS-10, in Neurospora crassa leads to altered mitochondrial morphology, instability of mtDNA and senescence. Genetics (2010) 0.79
Mitochondrial control of cell bioenergetics in Parkinson's disease. Free Radic Biol Med (2016) 0.78
Potential Role of Caffeine in the Treatment of Parkinson's Disease. Open Neurol J (2016) 0.75
Parkin deficiency exacerbate ethanol-induced dopaminergic neurodegeneration by P38 pathway dependent inhibition of autophagy and mitochondrial function. Redox Biol (2016) 0.75