Published in Blood on October 05, 2006
Naive T cell homeostasis: from awareness of space to a sense of place. Nat Rev Immunol (2009) 2.68
Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival. J Leukoc Biol (2008) 2.34
IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival. Blood (2007) 2.24
Murine neonatal recent thymic emigrants are phenotypically and functionally distinct from adult recent thymic emigrants. Blood (2009) 1.95
IL-7 signaling must be intermittent, not continuous, during CD8⁺ T cell homeostasis to promote cell survival instead of cell death. Nat Immunol (2012) 1.93
Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling. Nat Chem Biol (2016) 1.49
IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis. Semin Immunol (2012) 1.27
STAT5 is critical to maintain effector CD8+ T cell responses. J Immunol (2010) 1.25
Signaling thresholds govern heterogeneity in IL-7-receptor-mediated responses of naïve CD8(+) T cells. Immunol Cell Biol (2011) 1.14
Modulating T-cell homeostasis with IL-7: preclinical and clinical studies. J Intern Med (2009) 1.14
Interlinking interleukin-7. Cytokine (2007) 1.14
Dual mechanism of impairment of interleukin-7 (IL-7) responses in human immunodeficiency virus infection: decreased IL-7 binding and abnormal activation of the JAK/STAT5 pathway. J Virol (2010) 1.00
Increased CD4+ T cell levels during IL-7 administration of antiretroviral therapy-treated simian immunodeficiency virus-positive macaques are not dependent on strong proliferative responses. J Immunol (2010) 0.98
Isolated receptor binding domains of HTLV-1 and HTLV-2 envelopes bind Glut-1 on activated CD4+ and CD8+ T cells. Retrovirology (2007) 0.96
Molecular and cellular basis of T cell lineage commitment. Semin Immunol (2010) 0.96
Interleukin-7 mediates glucose utilization in lymphocytes through transcriptional regulation of the hexokinase II gene. Am J Physiol Cell Physiol (2010) 0.92
Ex vivo expansion of memory CD8 T cells from lymph nodes or spleen through in vitro culture with interleukin-7. J Immunol Methods (2009) 0.90
Haematological malignancies: at the forefront of immunotherapeutic innovation. Nat Rev Cancer (2015) 0.88
Mechanism of Action of IL-7 and Its Potential Applications and Limitations in Cancer Immunotherapy. Int J Mol Sci (2015) 0.88
IL-2 receptor gamma chain cytokines differentially regulate human CD8+CD127+ and CD8+CD127- T cell division and susceptibility to apoptosis. Int Immunol (2008) 0.85
Neonatal thymectomy reveals differentiation and plasticity within human naive T cells. J Clin Invest (2016) 0.85
Clonally diverse T cell homeostasis is maintained by a common program of cell-cycle control. J Immunol (2013) 0.83
Cell surface Glut1 levels distinguish human CD4 and CD8 T lymphocyte subsets with distinct effector functions. Sci Rep (2016) 0.81
Quantifying and predicting the effect of exogenous interleukin-7 on CD4+ T cells in HIV-1 infection. PLoS Comput Biol (2014) 0.80
The major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes. Biochim Biophys Acta (2012) 0.80
IL-18 synergizes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals. J Immunol (2014) 0.80
Heterogeneity in the CD4 T Cell Compartment and the Variability of Neonatal Immune Responsiveness. Curr Immunol Rev (2007) 0.79
Lipid and Protein Co-Regulation of PI3K Effectors Akt and Itk in Lymphocytes. Front Immunol (2015) 0.78
Homeostatic expansion as a barrier to lymphocyte depletion strategies. Curr Opin Organ Transplant (2014) 0.76
A tightly regulated IL-22 response maintains immune functions and homeostasis in systemic viral infection. Sci Rep (2017) 0.75
Generalized Liver- and Blood-Derived CD8+ T-Cell Impairment in Response to Cytokines in Chronic Hepatitis C Virus Infection. PLoS One (2016) 0.75
Imatinib mesylate inhibits STAT5 phosphorylation in response to IL-7 and promotes T cell lymphopenia in chronic myelogenous leukemia patients. Blood Cancer J (2017) 0.75
Erythrocyte Glut1 triggers dehydroascorbic acid uptake in mammals unable to synthesize vitamin C. Cell (2008) 2.84
Human muscle satellite cells as targets of Chikungunya virus infection. PLoS One (2007) 2.47
The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. Cell (2003) 2.28
Innate sensing of HIV-infected cells. PLoS Pathog (2011) 2.22
Type I IFN controls chikungunya virus via its action on nonhematopoietic cells. J Exp Med (2010) 1.86
Tetherin restricts productive HIV-1 cell-to-cell transmission. PLoS Pathog (2010) 1.73
ZAP-70 kinase regulates HIV cell-to-cell spread and virological synapse formation. EMBO J (2007) 1.68
The proteasome regulates HIV-1 transcription by both proteolytic and nonproteolytic mechanisms. Mol Cell (2007) 1.56
Solution structure of human prolactin. J Mol Biol (2005) 1.52
HepG2 cells expressing microRNA miR-122 support the entire hepatitis C virus life cycle. J Virol (2011) 1.37
RNA polymerase II kinetics in polo polyadenylation signal selection. EMBO J (2011) 1.34
Partial inhibition of human immunodeficiency virus replication by type I interferons: impact of cell-to-cell viral transfer. J Virol (2009) 1.21
IL-7 surface-engineered lentiviral vectors promote survival and efficient gene transfer in resting primary T lymphocytes. Blood (2002) 1.21
Homeostasis of naive and memory CD4+ T cells: IL-2 and IL-7 differentially regulate the balance between proliferation and Fas-mediated apoptosis. J Immunol (2003) 1.15
Glucose transporter 1 expression identifies a population of cycling CD4+ CD8+ human thymocytes with high CXCR4-induced chemotaxis. Proc Natl Acad Sci U S A (2005) 1.12
Species-specific regions of occludin required by hepatitis C virus for cell entry. J Virol (2010) 1.07
Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish. PLoS Pathog (2013) 1.06
Memory-like CD8+ and CD4+ T cells cooperate to break peripheral tolerance under lymphopenic conditions. Proc Natl Acad Sci U S A (2008) 1.06
KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development. Cell Stem Cell (2013) 1.06
HTLV-1 tropism and envelope receptor. Oncogene (2005) 1.05
Development of adoptive cell therapy for cancer: a clinical perspective. Hum Gene Ther (2010) 1.03
Glut1-mediated glucose transport regulates HIV infection. Proc Natl Acad Sci U S A (2012) 1.02
The HTLV receptor is an early T-cell activation marker whose expression requires de novo protein synthesis. Blood (2002) 1.02
HepG2 cells mount an effective antiviral interferon-lambda based innate immune response to hepatitis C virus infection. Hepatology (2014) 0.99
The Glut1 and Glut4 glucose transporters are differentially expressed during perinatal and postnatal erythropoiesis. Blood (2008) 0.98
Isolated receptor binding domains of HTLV-1 and HTLV-2 envelopes bind Glut-1 on activated CD4+ and CD8+ T cells. Retrovirology (2007) 0.96
Molecular and cellular basis of T cell lineage commitment. Semin Immunol (2010) 0.96
IL-7R alpha gene expression is inversely correlated with cell cycle progression in IL-7-stimulated T lymphocytes. J Immunol (2006) 0.95
Erythroid glucose transporters. Curr Opin Hematol (2009) 0.95
In vivo correction of ZAP-70 immunodeficiency by intrathymic gene transfer. J Clin Invest (2005) 0.92
Intrathymic administration of hematopoietic progenitor cells enhances T cell reconstitution in ZAP-70 severe combined immunodeficiency. Proc Natl Acad Sci U S A (2005) 0.91
Metabolic adaptation of neutrophils in cystic fibrosis airways involves distinct shifts in nutrient transporter expression. J Immunol (2013) 0.89
Intrathymic transplantation of bone marrow-derived progenitors provides long-term thymopoiesis. Blood (2009) 0.89
Optimization of tumor xenograft dissociation for the profiling of cell surface markers and nutrient transporters. Lab Invest (2013) 0.86
Lentiviral transduction of immune cells. Methods Mol Biol (2008) 0.86
T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk. Blood (2004) 0.85
Reconstitution of lymphoid development and function in ZAP-70-deficient mice following gene transfer into bone marrow cells. Blood (2002) 0.85
Cytokine stimulation and the choice of promoter are critical factors for the efficient transduction of mouse T cells with HIV-1 vectors. J Gene Med (2010) 0.84
Tumor necrosis factor promotes human T-cell development in nonobese diabetic/severe combined immunodeficient mice. Stem Cells (2004) 0.84
Molecular cloning and analysis of SSc5D, a new member of the scavenger receptor cysteine-rich superfamily. Mol Immunol (2009) 0.81
gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes. Blood (2002) 0.80
Intrathymic progenitor cell transplantation across histocompatibility barriers results in the persistence of early thymic progenitors and T-cell differentiation. Blood (2013) 0.80
HTLV envelopes and their receptor GLUT1, the ubiquitous glucose transporter: a new vision on HTLV infection? Front Biosci (2004) 0.80
IL-2 mediates CD4+ T cell help in the breakdown of memory-like CD8+ T cell tolerance under lymphopenic conditions. PLoS One (2010) 0.80
Efficient intrathymic gene transfer following in situ administration of a rAAV serotype 8 vector in mice and nonhuman primates. Mol Ther (2008) 0.80
IL-7 and CD4+ T-cell proliferation. Blood (2002) 0.79
Metabolic pathways as regulators of HIV infection. Curr Opin HIV AIDS (2013) 0.79
Cell surface expression of the bovine leukemia virus-binding receptor on B and T lymphocytes is induced by receptor engagement. J Immunol (2008) 0.78
HIV-1 Nef promotes the localization of Gag to the cell membrane and facilitates viral cell-to-cell transfer. Retrovirology (2013) 0.78
The protooncogene Vav1 regulates murine leukemia virus-induced T-cell leukemogenesis. Oncoimmunology (2012) 0.77
Redirecting the immune response: role of adoptive T cell therapy. Hum Gene Ther (2010) 0.77
Ex vivo isolation protocols differentially affect the phenotype of human CD4+ T cells. J Immunol Methods (2002) 0.76
Concise review: hematopoietic stem cell transplantation: targeting the thymus. Stem Cells (2013) 0.76
The Global Thymus Network: past, present and future. Trends Immunol (2009) 0.76
Metabolic regulation of hematopoietic stem cell commitment and erythroid differentiation. Curr Opin Hematol (2016) 0.76
Hematopoietic stem cell lineage specification. Curr Opin Hematol (2016) 0.76
In vivo and ex vivo gene transfer in thymocytes and thymocyte precursors. Methods Mol Biol (2009) 0.75
S179D-Human PRL, a Pseudophosphorylated Human PRL Analog, Is an Agonist and Not an Antagonist. Endocrinology (2001) 0.75
[Red cell GLUT1 compensates for the lack of vitamin C synthesis in mammals]. Med Sci (Paris) (2008) 0.75
[GLUT-1 is the receptor of retrovirus HTLV]. Med Sci (Paris) (2004) 0.75