Published in Magn Reson Med on November 01, 2006
Models, mechanisms and clinical evidence for cancer dormancy. Nat Rev Cancer (2007) 6.58
Serpins promote cancer cell survival and vascular co-option in brain metastasis. Cell (2014) 3.04
Does tumour dormancy offer a therapeutic target? Nat Rev Cancer (2010) 2.19
The biology of brain metastases-translation to new therapies. Nat Rev Clin Oncol (2011) 2.16
Reactive glia are recruited by highly proliferative brain metastases of breast cancer and promote tumor cell colonization. Clin Exp Metastasis (2008) 2.11
Mechanisms of disseminated cancer cell dormancy: an awakening field. Nat Rev Cancer (2014) 2.09
Metastatic stem cells: sources, niches, and vital pathways. Cell Stem Cell (2014) 1.88
Detection and quantification of magnetically labeled cells by cellular MRI. Eur J Radiol (2008) 1.87
Capturing changes in the brain microenvironment during initial steps of breast cancer brain metastasis. Am J Pathol (2010) 1.68
Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol (2008) 1.60
In vivo animal models for studying brain metastasis: value and limitations. Clin Exp Metastasis (2013) 1.52
Metastatic colonization by circulating tumour cells. Nature (2016) 1.31
Clinical opportunities and challenges in targeting tumour dormancy. Nat Rev Clin Oncol (2012) 1.26
Tumour dormancy in breast cancer: an update. Breast Cancer Res (2007) 1.23
Molecular MRI for sensitive and specific detection of lung metastases. Proc Natl Acad Sci U S A (2010) 1.23
Computational morphometry for detecting changes in brain structure due to development, aging, learning, disease and evolution. Front Neuroinform (2009) 1.13
In Vivo Cellular Imaging for Translational Medical Research. Curr Med Imaging Rev (2009) 1.12
Magnetic tagging of therapeutic cells for MRI. J Nucl Med (2009) 1.11
Molecular MRI enables early and sensitive detection of brain metastases. Proc Natl Acad Sci U S A (2012) 1.10
Noninvasive imaging of the functional effects of anti-VEGF therapy on tumor cell extravasation and regional blood volume in an experimental brain metastasis model. Clin Exp Metastasis (2009) 1.10
The role of MMP-1 in breast cancer growth and metastasis to the brain in a xenograft model. BMC Cancer (2012) 1.08
Cellular magnetic resonance imaging: in vivo imaging of melanoma cells in lymph nodes of mice. Neoplasia (2008) 1.04
Rat model of metastatic breast cancer monitored by MRI at 3 tesla and bioluminescence imaging with histological correlation. J Transl Med (2009) 1.03
Caught in the act: revealing the metastatic process by live imaging. Dis Model Mech (2013) 0.99
Stem cell tracking by nanotechnologies. Int J Mol Sci (2010) 0.98
Molecular imaging of metastatic potential. J Nucl Med (2008) 0.94
BRMS1 suppresses breast cancer metastasis in multiple experimental models of metastasis by reducing solitary cell survival and inhibiting growth initiation. Clin Exp Metastasis (2008) 0.94
Magnetic resonance imaging of cells in experimental disease models. Prog Nucl Magn Reson Spectrosc (2009) 0.92
Differential microstructure and physiology of brain and bone metastases in a rat breast cancer model by diffusion and dynamic contrast enhanced MRI. Clin Exp Metastasis (2011) 0.92
Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations. Proc Natl Acad Sci U S A (2014) 0.91
In vivo single scan detection of both iron-labeled cells and breast cancer metastases in the mouse brain using balanced steady-state free precession imaging at 1.5 T. J Magn Reson Imaging (2011) 0.90
In Vivo Magnetic Resonance Imaging for Investigating the Development and Distribution of Experimental Brain Metastases due to Breast Cancer. Transl Oncol (2012) 0.88
Single-cell tumor dormancy model of uveal melanoma. Clin Exp Metastasis (2008) 0.88
Unsanctifying the sanctuary: challenges and opportunities with brain metastases. Neuro Oncol (2015) 0.87
DNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer. J Natl Cancer Inst (2014) 0.87
Molecular imaging in cardiovascular magnetic resonance imaging: current perspective and future potential. Top Magn Reson Imaging (2008) 0.87
Breast cancer brain metastases: a review of the literature and a current multidisciplinary management guideline. Clin Transl Oncol (2013) 0.87
Cell therapy in myocardial infarction: emphasis on the role of MRI. Eur Radiol (2007) 0.87
Preliminary characterization of an experimental breast cancer cells brain metastasis mouse model by MRI/MRS. MAGMA (2008) 0.86
Molecular interactions in the development of brain metastases. Int J Mol Sci (2013) 0.85
The synthetic triterpenoid CDDO-Imidazolide suppresses experimental liver metastasis. Clin Exp Metastasis (2011) 0.84
Characterization of passive permeability at the blood-tumor barrier in five preclinical models of brain metastases of breast cancer. Clin Exp Metastasis (2016) 0.83
Ex-vivo cellular MRI with b-SSFP: quantitative benefits of 3T over 1.5 T. MAGMA (2008) 0.83
Magnetization transfer contrast MRI for non-invasive assessment of innate and adaptive immune responses against alginate-encapsulated cells. Biomaterials (2014) 0.83
Single-cell tracking with PET using a novel trajectory reconstruction algorithm. IEEE Trans Med Imaging (2014) 0.82
Walker 256 tumour cells increase substance P immunoreactivity locally and modify the properties of the blood-brain barrier during extravasation and brain invasion. Clin Exp Metastasis (2012) 0.82
Clinical field-strength MRI of amyloid plaques induced by low-level cholesterol feeding in rabbits. Brain (2009) 0.82
Role of MTA2 in human cancer. Cancer Metastasis Rev (2014) 0.82
Delivery of fluorescent probes using iron oxide particles as carriers enables in-vivo labeling of migrating neural precursors for magnetic resonance imaging and optical imaging. J Biomed Opt (2007) 0.81
Multimodal imaging of stem cell implantation in the central nervous system of mice. J Vis Exp (2012) 0.81
Quantitative T2* imaging of metastatic human breast cancer to brain in the nude rat at 3 T. NMR Biomed (2010) 0.81
Biological activity and magnetic resonance imaging of superparamagnetic iron oxide nanoparticles-labeled adipose-derived stem cells. Stem Cell Res Ther (2013) 0.80
Synergistic effect of therapeutic stem cells expressing cytosine deaminase and interferon-beta via apoptotic pathway in the metastatic mouse model of breast cancer. Oncotarget (2016) 0.80
Nanoparticles coated with the tumor-penetrating peptide iRGD reduce experimental breast cancer metastasis in the brain. J Mol Med (Berl) (2015) 0.79
Analysis of radiation therapy in a model of triple-negative breast cancer brain metastasis. Clin Exp Metastasis (2015) 0.78
In vivo MRI discrimination between live and lysed iron-labelled cells using balanced steady state free precession. Eur Radiol (2012) 0.78
Phase contrast MRI is an early marker of micrometastatic breast cancer development in the rat brain. NMR Biomed (2011) 0.78
Understanding Heterogeneity and Permeability of Brain Metastases in Murine Models of HER2-Positive Breast Cancer Through Magnetic Resonance Imaging: Implications for Detection and Therapy. Transl Oncol (2015) 0.78
Generalized principles of stochasticity can be used to control dynamic heterogeneity. Phys Biol (2012) 0.78
Molecular and Genetic Predictors of Breast-to-Brain Metastasis: Review and Case Presentation. Cureus (2015) 0.77
A novel preclinical method to quantitatively evaluate early-stage metastatic events at the murine blood-brain barrier. Cancer Prev Res (Phila) (2014) 0.77
Tracking Transplanted Stem Cells Using Magnetic Resonance Imaging and the Nanoparticle Labeling Method in Urology. Biomed Res Int (2015) 0.76
Molecular and functional imaging of invasion and metastasis: windows into the metastatic cascade. Cancer Biomark (2010) 0.76
Extracellular Vesicles in Brain Tumor Progression. Cell Mol Neurobiol (2016) 0.76
IL-6 receptor is a possible target against growth of metastasized lung tumor cells in the brain. Int J Mol Sci (2012) 0.76
Pharmacogenomics and cancer stem cells: a changing landscape? Trends Pharmacol Sci (2011) 0.76
Characterisation of Walker 256 breast carcinoma cells from two tumour cell banks as assessed using two models of secondary brain tumours. Cancer Cell Int (2013) 0.75
Cancer: Disabling defences in the brain. Nature (2014) 0.75
Magnetic Resonance Microscopy (MRM) of Single Mammalian Myofibers and Myonuclei. Sci Rep (2017) 0.75
Monitoring cancer stem cells: insights into clinical oncology. Onco Targets Ther (2016) 0.75
Breast Cancer Brain Metastases: Clonal Evolution in Clinical Context. Int J Mol Sci (2017) 0.75
A multimodality imaging model to track viable breast cancer cells from single arrest to metastasis in the mouse brain. Sci Rep (2016) 0.75
Cancer and the metastatic substrate. Ecancermedicalscience (2016) 0.75
MRI detection of nonproliferative tumor cells in lymph node metastases using iron oxide particles in a mouse model of breast cancer. Transl Oncol (2013) 0.75
Magnetic resonance imaging of odorant activity-dependent migration of neural precursor cells and olfactory bulb growth. Neuroimage (2017) 0.75
Three-dimensional spatiotemporal tracking of fluorine-18 radiolabeled yeast cells via positron emission particle tracking. PLoS One (2017) 0.75
In vivo magnetic resonance imaging investigating the development of experimental brain metastases due to triple negative breast cancer. Clin Exp Metastasis (2017) 0.75
Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer (2002) 17.49
Rapid combined T1 and T2 mapping using gradient recalled acquisition in the steady state. Magn Reson Med (2003) 3.56
Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts. J Natl Cancer Inst (2002) 3.39
Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer. Clin Cancer Res (2010) 3.35
Breast cancer metastasis to the central nervous system. Am J Pathol (2005) 3.30
Direct activation of the ventral striatum in anticipation of aversive stimuli. Neuron (2003) 2.99
High-resolution T1 and T2 mapping of the brain in a clinically acceptable time with DESPOT1 and DESPOT2. Magn Reson Med (2005) 2.91
Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling. J Natl Cancer Inst (2002) 2.77
Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain. Cancer Res (2007) 2.66
Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton. Cancer Res (2008) 2.63
Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer. J Natl Cancer Inst (2005) 2.60
A cortical network sensitive to stimulus salience in a neutral behavioral context across multiple sensory modalities. J Neurophysiol (2002) 2.41
Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation. Nat Cell Biol (2009) 2.38
Gleaning multicomponent T1 and T2 information from steady-state imaging data. Magn Reson Med (2008) 2.38
Persistence of solitary mammary carcinoma cells in a secondary site: a possible contributor to dormancy. Cancer Res (2002) 2.36
Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologies. Clin Cancer Res (2004) 2.33
In vivo magnetic resonance imaging of single cells in mouse brain with optical validation. Magn Reson Med (2006) 2.32
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. J Clin Invest (2004) 2.31
Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain. J Natl Cancer Inst (2008) 2.24
Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo. Clin Cancer Res (2007) 2.22
Does tumour dormancy offer a therapeutic target? Nat Rev Cancer (2010) 2.19
Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases. Breast Cancer Res Treat (2003) 2.14
Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growth. Eur J Cancer (2010) 2.13
BMP2 regulates Osterix through Msx2 and Runx2 during osteoblast differentiation. J Biol Chem (2008) 2.12
Reactive glia are recruited by highly proliferative brain metastases of breast cancer and promote tumor cell colonization. Clin Exp Metastasis (2008) 2.11
Co-localization of cortactin and phosphotyrosine identifies active invadopodia in human breast cancer cells. Exp Cell Res (2006) 1.96
Application of the static dephasing regime theory to superparamagnetic iron-oxide loaded cells. Magn Reson Med (2002) 1.95
Angiogenesis inhibitors: motivators of metastasis? Nat Med (2003) 1.95
Hypoxia and hypoxia-inducible factor-1 expression enhance osteolytic bone metastases of breast cancer. Cancer Res (2007) 1.77
Cancer spread and micrometastasis development: quantitative approaches for in vivo models. Bioessays (2002) 1.76
Differential roles of Smad1 and p38 kinase in regulation of peroxisome proliferator-activating receptor gamma during bone morphogenetic protein 2-induced adipogenesis. Mol Biol Cell (2003) 1.73
The biology of metastasis to a sanctuary site. Clin Cancer Res (2007) 1.72
Mapping cerebrovascular reactivity using blood oxygen level-dependent MRI in Patients with arterial steno-occlusive disease: comparison with arterial spin labeling MRI. Stroke (2008) 1.69
Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol (2009) 1.69
The Wnt antagonist Frzb-1 regulates chondrocyte maturation and long bone development during limb skeletogenesis. Dev Biol (2002) 1.68
Functional gene screening system identified TRPV4 as a regulator of chondrogenic differentiation. J Biol Chem (2007) 1.66
Bone-derived IGF mediates crosstalk between bone and breast cancer cells in bony metastases. Cancer Res (2012) 1.65
Separate brain regions code for salience vs. valence during reward prediction in humans. Hum Brain Mapp (2007) 1.64
Reciprocal roles of MSX2 in regulation of osteoblast and adipocyte differentiation. J Biol Chem (2004) 1.64
Cellular MRI contrast via coexpression of transferrin receptor and ferritin. Magn Reson Med (2006) 1.64
Breast cancer metastasis: challenges and opportunities. Cancer Res (2009) 1.63
Proteomics of human breast ductal carcinoma in situ. Cancer Res (2002) 1.62
Cancer metastasis as a therapeutic target. Eur J Cancer (2010) 1.60
Localization of clinically effective stimulating electrodes in the human subthalamic nucleus on magnetic resonance imaging. J Neurosurg (2002) 1.60
Changes over time of extracellular domain of HER2 (ECD/HER2) serum levels have prognostic value in metastatic breast cancer. Breast Cancer Res Treat (2008) 1.59
Detection threshold of single SPIO-labeled cells with FIESTA. Magn Reson Med (2005) 1.59
New dual monoclonal ELISA for measuring plasma osteopontin as a biomarker associated with survival in prostate cancer: clinical validation and comparison of multiple ELISAs. Clin Chem (2009) 1.59
Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function. Mol Biol Cell (2007) 1.57
Impaired peri-nidal cerebrovascular reserve in seizure patients with brain arteriovenous malformations. Brain (2010) 1.56
Dormancy of solitary metastatic cells. Cell Cycle (2006) 1.53
Role of the metastasis-promoting protein osteopontin in the tumour microenvironment. J Cell Mol Med (2010) 1.53
C-SRC tyrosine kinase activity is associated with tumor colonization in bone and lung in an animal model of human breast cancer metastasis. Cancer Res (2003) 1.52
Zoledronic acid inhibits visceral metastases in the 4T1/luc mouse breast cancer model. Clin Cancer Res (2004) 1.52
Thematic review series: Adipocyte Biology. Lipodystrophies: windows on adipose biology and metabolism. J Lipid Res (2007) 1.52
Combined breast ductal lavage and ductal endoscopy for the evaluation of the high-risk breast: a feasibility study. J Surg Oncol (2006) 1.51
Imaging single mammalian cells with a 1.5 T clinical MRI scanner. Magn Reson Med (2003) 1.51
Visual-spatial ability and fMRI cortical activation in surgery residents. Am J Surg (2007) 1.51
Viewing artworks: contributions of cognitive control and perceptual facilitation to aesthetic experience. Brain Cogn (2009) 1.50
Serial plasma osteopontin levels have prognostic value in metastatic breast cancer. Clin Cancer Res (2006) 1.49
Plasma osteopontin: associations with survival and metastasis to bone in men with hormone-refractory prostate carcinoma. Cancer (2002) 1.49
Osteopontin overexpression in breast cancer: knowledge gained and possible implications for clinical management. J Cell Biochem (2007) 1.48
Lapatinib distribution in HER2 overexpressing experimental brain metastases of breast cancer. Pharm Res (2011) 1.46
Bilateral horizontal gaze palsy in presumed paraneoplastic brainstem encephalitis associated with a benign ovarian teratoma. J Neuroophthalmol (2004) 1.45
Quantitative assessment of carotid plaque composition using multicontrast MRI and registered histology. Magn Reson Med (2003) 1.41
Metastasis suppressor genes: basic biology and potential clinical use. Clin Breast Cancer (2003) 1.41
Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks. Clin Cancer Res (2009) 1.40
Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-kappaB activation. Mol Cancer (2007) 1.40
Reconstruction of carotid bifurcation hemodynamics and wall thickness using computational fluid dynamics and MRI. Magn Reson Med (2002) 1.38
Biodistribution of neural stem cells after intravascular therapy for hypoxic-ischemia. Stroke (2010) 1.37
Tumor-derived platelet-derived growth factor-BB plays a critical role in osteosclerotic bone metastasis in an animal model of human breast cancer. Cancer Res (2002) 1.37
NAD(P)H oxidases regulate HIF-2alpha protein expression. J Biol Chem (2007) 1.37
Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis. Mol Cancer Res (2009) 1.36
Phase I trial of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG), a heat shock protein inhibitor, administered twice weekly in patients with advanced malignancies. Eur J Cancer (2009) 1.36
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2. Cancer Res (2007) 1.35
CNS metastases in breast cancer: old challenge, new frontiers. Clin Cancer Res (2013) 1.35
Sensorimotor cortical plasticity during recovery following spinal cord injury: a longitudinal fMRI study. Neurorehabil Neural Repair (2007) 1.35
A flavonoid fraction from cranberry extract inhibits proliferation of human tumor cell lines. J Nutr (2004) 1.32
Selective reduction of blood flow to white matter during hypercapnia corresponds with leukoaraiosis. Stroke (2008) 1.31
A CCAAT/enhancer binding protein beta isoform, liver-enriched inhibitory protein, regulates commitment of osteoblasts and adipocytes. Mol Cell Biol (2005) 1.30