Published in Genes Genet Syst on August 01, 2006
Structure, organization and tissue expression of the pig SLC13A1 and SLC13A4 sulfate transporter genes. Biochem Biophys Rep (2017) 0.75
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels. Proc Natl Acad Sci U S A (2006) 2.16
Loss of TMEM16A causes a defect in epithelial Ca2+-dependent chloride transport. J Biol Chem (2009) 2.07
TMEM16A induces MAPK and contributes directly to tumorigenesis and cancer progression. Cancer Res (2012) 1.98
Expression and function of epithelial anoctamins. J Biol Chem (2010) 1.95
TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A. J Biol Chem (2009) 1.89
Calmodulin-dependent activation of the epithelial calcium-dependent chloride channel TMEM16A. FASEB J (2010) 1.78
The role of putative phosphorylation sites in the targeting and shuttling of the aquaporin-2 water channel. J Biol Chem (2002) 1.69
Anoctamins are a family of Ca2+-activated Cl- channels. J Cell Sci (2012) 1.55
Molecular targeting of CFTR as a therapeutic approach to cystic fibrosis. Trends Pharmacol Sci (2007) 1.55
Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9. J Biol Chem (2002) 1.50
Anoctamin 6 is an essential component of the outwardly rectifying chloride channel. Proc Natl Acad Sci U S A (2011) 1.46
Urolithiasis and hepatotoxicity are linked to the anion transporter Sat1 in mice. J Clin Invest (2010) 1.38
Bestrophin 1 and 2 are components of the Ca(2+) activated Cl(-) conductance in mouse airways. Biochim Biophys Acta (2008) 1.33
Bestrophin-1 enables Ca2+-activated Cl- conductance in epithelia. J Biol Chem (2006) 1.31
Isoforms of SLC26A6 mediate anion transport and have functional PDZ interaction domains. Am J Physiol Cell Physiol (2002) 1.29
Enhanced expression of ANO1 in head and neck squamous cell carcinoma causes cell migration and correlates with poor prognosis. PLoS One (2012) 1.26
The DeltaF508 mutation results in loss of CFTR function and mature protein in native human colon. Gastroenterology (2004) 1.25
Mechanistic insight into control of CFTR by AMPK. J Biol Chem (2008) 1.21
Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid system. Mol Cell Proteomics (2008) 1.18
Disruption of the K+ channel beta-subunit KCNE3 reveals an important role in intestinal and tracheal Cl- transport. J Biol Chem (2010) 1.15
Expression of voltage-gated potassium channels in human and mouse colonic carcinoma. Clin Cancer Res (2007) 1.15
Cl transport in complemented CF bronchial epithelial cells correlates with CFTR mRNA expression levels. Cell Physiol Biochem (2008) 1.10
Modulation of Ca2+-activated Cl- secretion by basolateral K+ channels in human normal and cystic fibrosis airway epithelia. Pediatr Res (2003) 1.09
Role of anoctamins in cancer and apoptosis. Philos Trans R Soc Lond B Biol Sci (2014) 1.04
Voltage-gated K+ channels support proliferation of colonic carcinoma cells. FASEB J (2006) 1.04
CFTR Cl- channel function in native human colon correlates with the genotype and phenotype in cystic fibrosis. Gastroenterology (2004) 1.04
ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel. Pflugers Arch (2009) 1.04
Purinergic P2Y6 receptors induce Ca2+ and CFTR dependent Cl- secretion in mouse trachea. Cell Physiol Biochem (2005) 1.03
CFTR and TMEM16A are separate but functionally related Cl- channels. Cell Physiol Biochem (2011) 1.02
Hyposulfatemia, growth retardation, reduced fertility, and seizures in mice lacking a functional NaSi-1 gene. Proc Natl Acad Sci U S A (2003) 1.02
Control of ion transport in mammalian airways by protease activated receptors type 2 (PAR-2). FASEB J (2005) 1.00
Rotavirus toxin NSP4 induces diarrhea by activation of TMEM16A and inhibition of Na+ absorption. Pflugers Arch (2011) 1.00
Slc26a6: a cardiac chloride-hydroxyl exchanger and predominant chloride-bicarbonate exchanger of the mouse heart. J Physiol (2004) 0.98
Cl- interference with the epithelial Na+ channel ENaC. J Biol Chem (2005) 0.97
AMPK controls epithelial Na(+) channels through Nedd4-2 and causes an epithelial phenotype when mutated. Pflugers Arch (2009) 0.97
The mouse sulfate anion transporter gene Sat1 (Slc26a1): cloning, tissue distribution, gene structure, functional characterization, and transcriptional regulation thyroid hormone. DNA Cell Biol (2003) 0.96
Eag1 and Bestrophin 1 are up-regulated in fast-growing colonic cancer cells. J Biol Chem (2008) 0.96
Characterization of the human sulfate anion transporter (hsat-1) protein and gene (SAT1; SLC26A1). DNA Cell Biol (2003) 0.96
Activation of ion secretion via proteinase-activated receptor-2 in human colon. Am J Physiol Gastrointest Liver Physiol (2002) 0.96
Regulation of the epithelial Na+ channel by the protein kinase CK2. J Biol Chem (2008) 0.95
Role of KCNMA1 in breast cancer. PLoS One (2012) 0.94
Correction of the CF defect by curcumin: hypes and disappointments. Bioessays (2005) 0.94
Inhibition of protein kinase CK2 closes the CFTR Cl channel, but has no effect on the cystic fibrosis mutant deltaF508-CFTR. Cell Physiol Biochem (2009) 0.94
Assessment of CFTR function in rectal biopsies for the diagnosis of cystic fibrosis. J Cyst Fibros (2004) 0.93
Bestrophin 1 promotes epithelial-to-mesenchymal transition of renal collecting duct cells. J Am Soc Nephrol (2009) 0.92
Measurements of CFTR-mediated Cl- secretion in human rectal biopsies constitute a robust biomarker for Cystic Fibrosis diagnosis and prognosis. PLoS One (2012) 0.92
Expression and functional significance of the Ca(2+)-activated Cl(-) channel ANO6 in dendritic cells. Cell Physiol Biochem (2012) 0.92
CFTR is activated through stimulation of purinergic P2Y2 receptors. Pflugers Arch (2008) 0.91
Gene complementation of airway epithelium in the cystic fibrosis mouse is necessary and sufficient to correct the pathogen clearance and inflammatory abnormalities. Hum Mol Genet (2002) 0.91
Characterization of novel airway submucosal gland cell models for cystic fibrosis studies. Cell Physiol Biochem (2005) 0.91
Acute effects of parainfluenza virus on epithelial electrolyte transport. J Biol Chem (2004) 0.91
Failure of translation of human adenovirus mRNA in murine cancer cells can be partially overcome by L4-100K expression in vitro and in vivo. Mol Ther (2012) 0.90
Escherichia coli alpha-hemolysin triggers shrinkage of erythrocytes via K(Ca)3.1 and TMEM16A channels with subsequent phosphatidylserine exposure. J Biol Chem (2010) 0.90
Disruption of NaS1 sulfate transport function in mice leads to enhanced acetaminophen-induced hepatotoxicity. Hepatology (2006) 0.89
F508del-CFTR increases intracellular Ca(2+) signaling that causes enhanced calcium-dependent Cl(-) conductance in cystic fibrosis. Biochim Biophys Acta (2011) 0.88
Impaired memory and olfactory performance in NaSi-1 sulphate transporter deficient mice. Behav Brain Res (2005) 0.87
Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase A-induced activity. Mol Cell Biol (2011) 0.87
p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker. Mol Cancer (2010) 0.87
Retracted Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the deltaF508 mutation: F508 deletion disrupts a kinase-binding site. J Biol Chem (2007) 0.87
Hypoxia-inducible factor-1α causes renal cyst expansion through calcium-activated chloride secretion. J Am Soc Nephrol (2013) 0.87
Molecular evolution and functional divergence of the bestrophin protein family. BMC Evol Biol (2008) 0.86
High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets. Cell (2013) 0.86
Sat1 is dispensable for active oxalate secretion in mouse duodenum. Am J Physiol Cell Physiol (2012) 0.86
Functional assembly and purinergic activation of bestrophins. Pflugers Arch (2009) 0.86
Increase in intracellular Cl- concentration by cAMP- and Ca2+-dependent stimulation of M1 collecting duct cells. Pflugers Arch (2004) 0.86
A dileucine motif targets the sulfate anion transporter sat-1 to the basolateral membrane in renal cell lines. Am J Physiol Cell Physiol (2004) 0.86
Fetal loss and hyposulfataemia in pregnant NaS1 transporter null mice. J Reprod Dev (2011) 0.85
Characterisation of the fibroblast growth factor dependent transcriptome in early development. PLoS One (2009) 0.85
Inhibition of the inflammatory cytokine TNF-α increases adenovirus activity in ovarian cancer via modulation of cIAP1/2 expression. Mol Ther (2010) 0.85
Rectal forceps biopsy procedure in cystic fibrosis: technical aspects and patients perspective for clinical trials feasibility. BMC Gastroenterol (2013) 0.85
Regulation of Cl(-) secretion by AMPK in vivo. Pflugers Arch (2008) 0.84
Establishment and characterization of a novel polarized MDCK epithelial cellular model for CFTR studies. Cell Physiol Biochem (2005) 0.84
APC sensitive gastric acid secretion. Cell Physiol Biochem (2009) 0.84
IADS, a decomposition product of DIDS activates a cation conductance in Xenopus oocytes and human erythrocytes: new compound for the diagnosis of cystic fibrosis. Cell Physiol Biochem (2006) 0.83
Behavioural abnormalities of the hyposulphataemic Nas1 knock-out mouse. Behav Brain Res (2004) 0.83
Transcriptional profile reveals altered hepatic lipid and cholesterol metabolism in hyposulfatemic NaS1 null mice. Physiol Genomics (2006) 0.82
Upregulation of colonic ion channels in APC ( Min/+ ) mice. Pflugers Arch (2008) 0.82
An extract from the medicinal plant Phyllanthus acidus and its isolated compounds induce airway chloride secretion: A potential treatment for cystic fibrosis. Mol Pharmacol (2006) 0.82
Functional characterization and genomic organization of the human Na(+)-sulfate cotransporter hNaS2 gene (SLC13A4). Biochem Biophys Res Commun (2005) 0.82
Cloning and expression of the mouse glomerular podoplanin homologue gp38P. Nephrol Dial Transplant (2002) 0.82
Genomic DNA damage and ATR-Chk1 signaling determine oncolytic adenoviral efficacy in human ovarian cancer cells. J Clin Invest (2011) 0.82
Control of ion transport in mouse proximal and distal colon by prolactin. Cell Physiol Biochem (2007) 0.81
NaSi-1 and Sat-1: structure, function and transcriptional regulation of two genes encoding renal proximal tubular sulfate transporters. Int J Biochem Cell Biol (2005) 0.81
Functional genomics assays to study CFTR traffic and ENaC function. Methods Mol Biol (2011) 0.81
Polycystin-2 activity is controlled by transcriptional coactivator with PDZ binding motif and PALS1-associated tight junction protein. J Biol Chem (2010) 0.81
Regulation of ENaC biogenesis by the stress response protein SERP1. Pflugers Arch (2012) 0.81
Control of TMEM16A by INO-4995 and other inositolphosphates. Br J Pharmacol (2013) 0.80
Effect of Annexin A5 on CFTR: regulated traffic or scaffolding? Mol Membr Biol (2010) 0.80
CFTR mutations altering CFTR fragmentation. Biochem J (2013) 0.80
Anoctamins support calcium-dependent chloride secretion by facilitating calcium signaling in adult mouse intestine. Pflugers Arch (2014) 0.80
A disease-causing mutation illuminates the protein membrane topology of the kidney-expressed prohibitin homology (PHB) domain protein podocin. J Biol Chem (2014) 0.79
Regulation of murine hepatic hydroxysteroid sulfotransferase expression in hyposulfatemic mice and in a cell model of 3'-phosphoadenosine-5'-phosphosulfate deficiency. Drug Metab Dispos (2013) 0.79
Hyperserotonaemia and reduced brain serotonin levels in NaS1 sulphate transporter null mice. Neuroreport (2007) 0.79
The rat Na+-sulfate cotransporter rNaS2: functional characterization, tissue distribution, and gene (slc13a4) structure. Pflugers Arch (2005) 0.79