PubRank

Kenichi Ikejima

Author PubWeight™ 50.17‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver. Hepatology 2002 2.34
2 Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-A(y) mice. Hepatology 2009 1.71
3 Loss of autophagy promotes murine acetaminophen hepatotoxicity. J Gastroenterol 2011 1.61
4 Hyperresponsivity to low-dose endotoxin during progression to nonalcoholic steatohepatitis is regulated by leptin-mediated signaling. Cell Metab 2012 1.50
5 SMAD and p38 MAPK signaling pathways independently regulate alpha1(I) collagen gene expression in unstimulated and transforming growth factor-beta-stimulated hepatic stellate cells. J Biol Chem 2005 1.36
6 Liver diseases and metabolic syndrome. J Gastroenterol 2008 1.33
7 Translocation of iron from lysosomes into mitochondria is a key event during oxidative stress-induced hepatocellular injury. Hepatology 2008 1.31
8 Death receptor 5 mediated-apoptosis contributes to cholestatic liver disease. Proc Natl Acad Sci U S A 2008 1.24
9 Pioglitazone prevents early-phase hepatic fibrogenesis caused by carbon tetrachloride. Biochem Biophys Res Commun 2002 1.21
10 Thalidomide prevents alcoholic liver injury in rats through suppression of Kupffer cell sensitization and TNF-alpha production. Gastroenterology 2002 1.20
11 CD1d-restricted natural killer T cells contribute to hepatic inflammation and fibrogenesis in mice. J Hepatol 2010 1.19
12 Dietary glycine prevents chemical-induced experimental colitis in the rat. Gastroenterology 2003 1.18
13 Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy. J Gastroenterol 2009 1.08
14 Low molecular weight heparin prevents hepatic fibrogenesis caused by carbon tetrachloride in the rat. J Hepatol 2006 1.00
15 Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. Hepatol Res 2015 0.98
16 Ursolic acid ameliorates hepatic fibrosis in the rat by specific induction of apoptosis in hepatic stellate cells. J Hepatol 2010 0.94
17 Hepatic sinusoidal cells in health and disease: update from the 14th International Symposium. Liver Int 2009 0.93
18 Role of apoptosis in acetaminophen hepatotoxicity. J Gastroenterol Hepatol 2007 0.92
19 The tumor suppressor protein PTEN inhibits rat hepatic stellate cell activation. J Gastroenterol 2009 0.91
20 Sphingosine 1-phosphate protects rat liver sinusoidal endothelial cells from ethanol-induced apoptosis: Role of intracellular calcium and nitric oxide. Hepatology 2006 0.91
21 Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression. Biochem Biophys Res Commun 2011 0.91
22 Innate immune responses involving natural killer and natural killer T cells promote liver regeneration after partial hepatectomy in mice. Am J Physiol Gastrointest Liver Physiol 2012 0.90
23 Senescence marker protein-30 regulates Akt activity and contributes to cell survival in Hep G2 cells. Biochem Biophys Res Commun 2004 0.89
24 Ethanol-induced sensitization to endotoxin in Kupffer cells is dependent upon oxidative stress. Alcohol Clin Exp Res 2005 0.87
25 Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor. Biochem Biophys Res Commun 2004 0.86
26 Targeted gene delivery to sinusoidal endothelial cells: DNA nanoassociate bearing hyaluronan-glycocalyx. FASEB J 2004 0.85
27 Abnormality of autophagic function and cathepsin expression in the liver from patients with non-alcoholic fatty liver disease. Hepatol Res 2014 0.85
28 Exacerbation of dietary steatohepatitis and fibrosis in obese, diabetic KK-A(y) mice. Hepatol Res 2006 0.85
29 Suppression of autophagy sensitizes Kupffer cells to endotoxin. Hepatol Res 2012 0.84
30 Burn injury sensitizes rat Kupffer cells via mechanisms dependent on gut-derived endotoxin. J Gastroenterol 2004 0.84
31 Recurrent severe acute hepatitis caused by hypereosinophilic syndrome associated with elevated serum immunoglobulin G4 levels. Clin J Gastroenterol 2014 0.83
32 Glycine blocks the increase in intracellular free Ca2+ due to vasoactive mediators in hepatic parenchymal cells. Am J Physiol Gastrointest Liver Physiol 2002 0.83
33 Acute ethanol administration down-regulates toll-like receptor-4 in the murine liver. Hepatol Res 2002 0.83
34 Glycine as a therapeutic immuno-nutrient for alcoholic liver disease. Alcohol Clin Exp Res 2005 0.83
35 Dalteparin sodium prevents liver injury due to lipopolysaccharide in rat through suppression of tumor necrosis factor-alpha production by Kupffer cells. Alcohol Clin Exp Res 2003 0.82
36 Orthotopic hepatocellular carcinoma model with a controlled and reproducible tumorigenicity. J Gastroenterol Hepatol 2007 0.82
37 Protective effect of pioglitazone against endotoxin-induced liver injury through prevention of Kupffer cell sensitization. Alcohol Clin Exp Res 2005 0.80
38 A double-strand decoy DNA oligomer for NF-kappaB inhibits TNFalpha-induced ICAM-1 expression in sinusoidal endothelial cells. Biochem Biophys Res Commun 2002 0.79
39 Protective effect of thalidomide on endotoxin-induced liver injury. Alcohol Clin Exp Res 2003 0.79
40 The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-alpha in isolated rat Kupffer cells and exerts hepatoprotective effects in mice. Biochem Biophys Res Commun 2004 0.79
41 Diabetic KK-A(y) mice are highly susceptible to oxidative hepatocellular damage induced by acetaminophen. Am J Physiol Gastrointest Liver Physiol 2010 0.79
42 Hepatic steatosis is a predictor of poor response to interferon alpha-2b and ribavirin combination therapy in Japanese patients with chronic hepatitis C. Hepatol Res 2006 0.78
43 Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis. J Gastroenterol 2015 0.78
44 Oral contraceptives worsen endotoxin-induced liver injury in rats. Alcohol Clin Exp Res 2002 0.78
45 Estriol enhances lipopolysaccharide-induced increases in nitric oxide production by Kupffer cells via mechanisms dependent on endotoxin. Alcohol Clin Exp Res 2002 0.78
46 Thalidomide Prevents Alcoholic Liver Injury in Rats Through Inhibition of Kupffer Cell Sensitization. Comp Hepatol 2004 0.77
47 Glycine as a potent anti-angiogenic nutrient for tumor growth. J Gastroenterol Hepatol 2007 0.77
48 Anti-inflammatory strategies in alcoholic steatohepatitis. J Gastroenterol Hepatol 2007 0.77
49 [Gender difference in alcoholic liver injury]. Nihon Arukoru Yakubutsu Igakkai Zasshi 2004 0.76
50 Synthetic triglyceride containing an arachidonic acid branch (8A8) prevents lipopolysaccharide-induced liver injury. Life Sci 2009 0.76
51 Altered expression and function of hepatic natural killer T cells in obese and diabetic KK-A(y) mice. Hepatol Res 2012 0.76
52 [Ethanol changes sensitivity of Kupffer cells to endotoxin]. Nihon Arukoru Yakubutsu Igakkai Zasshi 2003 0.76
53 Genetic manipulation of sinusoidal endothelial cells. J Gastroenterol Hepatol 2007 0.75
54 The phosphodiesterase III inhibitor olprinone decreases sensitivity of rat Kupffer cells to endotoxin. Alcohol Clin Exp Res 2004 0.75
55 [Progress in the study of obesity. 2. The concept of leptin]. Nihon Naika Gakkai Zasshi 2006 0.75
56 [Serine protease inhibitors prevent alcoholic liver injury]. Nihon Arukoru Yakubutsu Igakkai Zasshi 2005 0.75
57 [Pathophysiology of NASH]. Nihon Shokakibyo Gakkai Zasshi 2004 0.75
58 [Clinical Importance of Non-alcoholic Fatty Liver Diseases. Topics: II. Complexity in pathogenesis of nonalcoholic fatty liver disease]. Nihon Naika Gakkai Zasshi 2016 0.75
59 [Anti-viral therapy of type C chronic hepatitis. 2. Progression of type C chronic hepatitis and resistance to treatment. 2) Participation of host factors]. Nihon Naika Gakkai Zasshi 2008 0.75