Published in Mol Microbiol on November 01, 2006
The global, ppGpp-mediated stringent response to amino acid starvation in Escherichia coli. Mol Microbiol (2008) 2.57
ppGpp conjures bacterial virulence. Microbiol Mol Biol Rev (2010) 1.97
Regulation of cell size in response to nutrient availability by fatty acid biosynthesis in Escherichia coli. Proc Natl Acad Sci U S A (2012) 1.91
Discretely calibrated regulatory loops controlled by ppGpp partition gene induction across the 'feast to famine' gradient in Escherichia coli. Mol Microbiol (2010) 1.82
The RelA/SpoT homolog (RSH) superfamily: distribution and functional evolution of ppGpp synthetases and hydrolases across the tree of life. PLoS One (2011) 1.70
The Borrelia burgdorferi RelA/SpoT Homolog and Stringent Response Regulate Survival in the Tick Vector and Global Gene Expression during Starvation. PLoS Pathog (2015) 1.54
ppGpp negatively impacts ribosome assembly affecting growth and antimicrobial tolerance in Gram-positive bacteria. Proc Natl Acad Sci U S A (2016) 1.48
Bacterial lipids: metabolism and membrane homeostasis. Prog Lipid Res (2013) 1.42
SpoT regulates DnaA stability and initiation of DNA replication in carbon-starved Caulobacter crescentus. J Bacteriol (2008) 1.41
Taxonomy, Physiology, and Natural Products of Actinobacteria. Microbiol Mol Biol Rev (2015) 1.36
Recent functional insights into the role of (p)ppGpp in bacterial physiology. Nat Rev Microbiol (2015) 1.35
ppGpp regulation of RpoS degradation via anti-adaptor protein IraP. Proc Natl Acad Sci U S A (2007) 1.31
Bacterial lifestyle shapes stringent response activation. Trends Microbiol (2013) 1.26
Regulation of the stringent response is the essential function of the conserved bacterial G protein CgtA in Vibrio cholerae. Proc Natl Acad Sci U S A (2007) 1.25
Antifolate-induced depletion of intracellular glycine and purines inhibits thymineless death in E. coli. ACS Chem Biol (2010) 1.23
Growth rate regulation in Escherichia coli. FEMS Microbiol Rev (2011) 1.23
Thematic review series: Glycerolipids. Acyltransferases in bacterial glycerophospholipid synthesis. J Lipid Res (2008) 1.22
Decline in ribosomal fidelity contributes to the accumulation and stabilization of the master stress response regulator sigmaS upon carbon starvation. Genes Dev (2007) 1.11
Bacteria possessing two RelA/SpoT-like proteins have evolved a specific stringent response involving the acyl carrier protein-SpoT interaction. J Bacteriol (2008) 1.07
Fatty acid synthesis in Escherichia coli and its applications towards the production of fatty acid based biofuels. Biotechnol Biofuels (2014) 1.07
The stringent response is essential for Pseudomonas aeruginosa virulence in the rat lung agar bead and Drosophila melanogaster feeding models of infection. Infect Immun (2011) 1.06
A metazoan ortholog of SpoT hydrolyzes ppGpp and functions in starvation responses. Nat Struct Mol Biol (2010) 1.06
Two small (p)ppGpp synthases in Staphylococcus aureus mediate tolerance against cell envelope stress conditions. J Bacteriol (2013) 1.04
Control of redox balance by the stringent response regulatory protein promotes antioxidant defenses of Salmonella. J Biol Chem (2010) 1.02
The role of relA and spoT in Yersinia pestis KIM5 pathogenicity. PLoS One (2009) 1.01
Transcription activity of individual rrn operons in Bacillus subtilis mutants deficient in (p)ppGpp synthetase genes, relA, yjbM, and ywaC. J Bacteriol (2009) 1.00
Whole-genome microarray and gene deletion studies reveal regulation of the polyhydroxyalkanoate production cycle by the stringent response in Ralstonia eutropha H16. Appl Environ Microbiol (2012) 1.00
The complex logic of stringent response regulation in Caulobacter crescentus: starvation signalling in an oligotrophic environment. Mol Microbiol (2011) 0.98
Cross-talk between two nucleotide-signaling pathways in Staphylococcus aureus. J Biol Chem (2015) 0.98
Stress response regulators identified through genome-wide transcriptome analysis of the (p)ppGpp-dependent response in Rhizobium etli. Genome Biol (2011) 0.97
Nutrient salvaging and metabolism by the intracellular pathogen Legionella pneumophila. Front Cell Infect Microbiol (2014) 0.96
Many means to a common end: the intricacies of (p)ppGpp metabolism and its control of bacterial homeostasis. J Bacteriol (2015) 0.95
Regulation of cell growth during serum starvation and bacterial survival in macrophages by the bifunctional enzyme SpoT in Helicobacter pylori. J Bacteriol (2008) 0.95
Dose-dependent reduction of replication elongation rate by (p)ppGpp in Escherichia coli and Bacillus subtilis. Mol Microbiol (2013) 0.95
Expression of a small (p)ppGpp synthetase, YwaC, in the (p)ppGpp(0) mutant of Bacillus subtilis triggers YvyD-dependent dimerization of ribosome. Microbiologyopen (2012) 0.93
Basal levels of (p)ppGpp in Enterococcus faecalis: the magic beyond the stringent response. MBio (2013) 0.92
From (p)ppGpp to (pp)pGpp: Characterization of Regulatory Effects of pGpp Synthesized by the Small Alarmone Synthetase of Enterococcus faecalis. J Bacteriol (2015) 0.91
The ObgE/CgtA GTPase influences the stringent response to amino acid starvation in Escherichia coli. Mol Microbiol (2009) 0.90
SpoT-triggered stringent response controls usp gene expression in Pseudomonas aeruginosa. J Bacteriol (2008) 0.88
The Francisella tularensis migR, trmE, and cphA genes contribute to F. tularensis pathogenicity island gene regulation and intracellular growth by modulation of the stress alarmone ppGpp. Infect Immun (2013) 0.88
Interplay between E. coli DnaK, ClpB and GrpE during protein disaggregation. J Mol Biol (2014) 0.87
Growth rate and cell size: a re-examination of the growth law. Curr Opin Microbiol (2015) 0.87
Stress sigma factor RpoS degradation and translation are sensitive to the state of central metabolism. Proc Natl Acad Sci U S A (2015) 0.87
Synthetic growth phenotypes of Escherichia coli lacking ppGpp and transketolase A (tktA) are due to ppGpp-mediated transcriptional regulation of tktB. Mol Microbiol (2008) 0.86
When Too Much ATP Is Bad for Protein Synthesis. J Mol Biol (2015) 0.86
A proximal promoter element required for positive transcriptional control by guanosine tetraphosphate and DksA protein during the stringent response. J Biol Chem (2013) 0.84
Characterization of a novel RNA polymerase mutant that alters DksA activity. J Bacteriol (2013) 0.84
Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress. BMC Microbiol (2010) 0.83
Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1. Eukaryot Cell (2009) 0.83
Pleiotropic effects of a rel mutation on stress survival of Rhizobium etli CNPAF512. BMC Microbiol (2008) 0.82
Sigma S-dependent antioxidant defense protects stationary-phase Escherichia coli against the bactericidal antibiotic gentamicin. Antimicrob Agents Chemother (2014) 0.82
Fatty acid biosynthesis revisited: structure elucidation and metabolic engineering. Mol Biosyst (2014) 0.82
Influence of the RelA Activity on E. coli Metabolism by Metabolite Profiling of Glucose-Limited Chemostat Cultures. Metabolites (2012) 0.81
Depletion of acidic phospholipids influences chromosomal replication in Escherichia coli. Microbiologyopen (2012) 0.81
FtsH-mediated coordination of lipopolysaccharide biosynthesis in Escherichia coli correlates with the growth rate and the alarmone (p)ppGpp. J Bacteriol (2013) 0.81
Disrupting the Acyl Carrier Protein/SpoT interaction in vivo: identification of ACP residues involved in the interaction and consequence on growth. PLoS One (2012) 0.80
(p)ppGpp modulates cell size and the initiation of DNA replication in Caulobacter crescentus in response to a block in lipid biosynthesis. Microbiology (2015) 0.79
Convergence of Alarmone and Cell Cycle Signaling from Trans-Encoded Sensory Domains. MBio (2015) 0.79
Nicotinic acid modulates Legionella pneumophila gene expression and induces virulence traits. Infect Immun (2013) 0.79
Genetic components of stringent response in Vibrio cholerae. Indian J Med Res (2011) 0.78
Phosphotransferase-dependent accumulation of (p)ppGpp in response to glutamine deprivation in Caulobacter crescentus. Nat Commun (2016) 0.78
Posttranslational maturation of the invasion acyl carrier protein of Salmonella enterica serovar Typhimurium requires an essential phosphopantetheinyl transferase of the fatty acid biosynthesis pathway. J Bacteriol (2013) 0.78
Inactivation of Cell Division Protein FtsZ by SulA Makes Lon Indispensable for the Viability of a ppGpp0 Strain of Escherichia coli. J Bacteriol (2015) 0.77
ppGpp metabolism is involved in heterocyst development in the cyanobacterium Anabaena sp. strain PCC 7120. J Bacteriol (2013) 0.77
Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Module-Encoded mRNases. J Bacteriol (2016) 0.77
(p)ppGpp, a Small Nucleotide Regulator, Directs the Metabolic Fate of Glucose in Vibrio cholerae. J Biol Chem (2015) 0.77
Identification of YbeY-Protein Interactions Involved in 16S rRNA Maturation and Stress Regulation in Escherichia coli. MBio (2016) 0.77
An Ancient Bacterial Signaling Pathway Regulates Chloroplast Function to Influence Growth and Development in Arabidopsis. Plant Cell (2016) 0.76
Fatty Acid Availability Sets Cell Envelope Capacity and Dictates Microbial Cell Size. Curr Biol (2017) 0.76
The roles of RelA/(p)ppGpp in glucose-starvation induced adaptive response in the zoonotic Streptococcus suis. Sci Rep (2016) 0.75
Inhibiting translation elongation can aid genome duplication in Escherichia coli. Nucleic Acids Res (2016) 0.75
Acylation of the Type 3 Secretion System Translocon Using a Dedicated Acyl Carrier Protein. PLoS Genet (2017) 0.75
A protein expression system for tandem affinity purification in Xanthomonas citri subsp. citri. Braz J Microbiol (2016) 0.75
The magic spot ppGpp influences in vitro the molecular and functional properties of the elongation factor 1α from the archaeon Sulfolobus solfataricus. Extremophiles (2012) 0.75
The bacterial two-hybrid system based on adenylate cyclase reconstitution in Escherichia coli. Methods (2012) 1.50
Bacteria possessing two RelA/SpoT-like proteins have evolved a specific stringent response involving the acyl carrier protein-SpoT interaction. J Bacteriol (2008) 1.07
The hotdog thioesterase EntH (YbdB) plays a role in vivo in optimal enterobactin biosynthesis by interacting with the ArCP domain of EntB. J Bacteriol (2007) 1.02
A protein network for phospholipid synthesis uncovered by a variant of the tandem affinity purification method in Escherichia coli. Proteomics (2006) 1.01
Tat HIV-1 primary and tertiary structures critical to immune response against non-homologous variants. J Biol Chem (2002) 1.00
Antagonistic regulation of dgkA and plsB genes of phospholipid synthesis by multiple stress responses in Escherichia coli. Mol Microbiol (2011) 0.92
Transcription of the Escherichia coli fatty acid synthesis operon fabHDG is directly activated by FadR and inhibited by ppGpp. J Bacteriol (2013) 0.88
Improvement of bacterial two-hybrid vectors for detection of fusion proteins and transfer to pBAD-tandem affinity purification, calmodulin binding peptide, or 6-histidine tag vectors. Proteomics (2008) 0.86
Disrupting the Acyl Carrier Protein/SpoT interaction in vivo: identification of ACP residues involved in the interaction and consequence on growth. PLoS One (2012) 0.80
Posttranslational maturation of the invasion acyl carrier protein of Salmonella enterica serovar Typhimurium requires an essential phosphopantetheinyl transferase of the fatty acid biosynthesis pathway. J Bacteriol (2013) 0.78
Tagging of Escherichia coli proteins with new cassettes allowing in vivo systematic fluorescent and luminescent detection, and purification from physiological expression levels. Proteomics (2009) 0.78