Published in Mol Microbiol on April 22, 2008
Active starvation responses mediate antibiotic tolerance in biofilms and nutrient-limited bacteria. Science (2011) 3.66
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Genomic analysis of oceanic cyanobacterial myoviruses compared with T4-like myoviruses from diverse hosts and environments. Environ Microbiol (2010) 2.23
Discretely calibrated regulatory loops controlled by ppGpp partition gene induction across the 'feast to famine' gradient in Escherichia coli. Mol Microbiol (2010) 1.82
The magic spot: a ppGpp binding site on E. coli RNA polymerase responsible for regulation of transcription initiation. Mol Cell (2013) 1.80
Three new RelE-homologous mRNA interferases of Escherichia coli differentially induced by environmental stresses. Mol Microbiol (2009) 1.76
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Direct regulation of Escherichia coli ribosomal protein promoters by the transcription factors ppGpp and DksA. Proc Natl Acad Sci U S A (2011) 1.56
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DksA and ppGpp directly regulate transcription of the Escherichia coli flagellar cascade. Mol Microbiol (2009) 1.29
RNA polymerase mutants found through adaptive evolution reprogram Escherichia coli for optimal growth in minimal media. Proc Natl Acad Sci U S A (2010) 1.27
Bacterial lifestyle shapes stringent response activation. Trends Microbiol (2013) 1.26
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The stringent response is essential for Pseudomonas aeruginosa virulence in the rat lung agar bead and Drosophila melanogaster feeding models of infection. Infect Immun (2011) 1.06
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Whole-genome microarray and gene deletion studies reveal regulation of the polyhydroxyalkanoate production cycle by the stringent response in Ralstonia eutropha H16. Appl Environ Microbiol (2012) 1.00
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GTP dysregulation in Bacillus subtilis cells lacking (p)ppGpp results in phenotypic amino acid auxotrophy and failure to adapt to nutrient downshift and regulate biosynthesis genes. J Bacteriol (2013) 0.95
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Functional characterization of exopolyphosphatase/guanosine pentaphosphate phosphohydrolase (PPX/GPPA) of Campylobacter jejuni. Virulence (2014) 0.92
Basal levels of (p)ppGpp in Enterococcus faecalis: the magic beyond the stringent response. MBio (2013) 0.92
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Global transcriptional analysis of the stringent response in Enterococcus faecalis. Microbiology (2012) 0.91
The dksA promoter is negatively feedback regulated by DksA and ppGpp. Mol Microbiol (2011) 0.91
ppGpp Binding to a Site at the RNAP-DksA Interface Accounts for Its Dramatic Effects on Transcription Initiation during the Stringent Response. Mol Cell (2016) 0.91
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Genome-wide screening of genes whose enhanced expression affects glycogen accumulation in Escherichia coli. DNA Res (2010) 0.90
The ObgE/CgtA GTPase influences the stringent response to amino acid starvation in Escherichia coli. Mol Microbiol (2009) 0.90
Diversity in (p)ppGpp metabolism and effectors. Curr Opin Microbiol (2015) 0.90
Persistence Increases in the Absence of the Alarmone Guanosine Tetraphosphate by Reducing Cell Growth. Sci Rep (2016) 0.90
Accumulation of inorganic polyphosphate enables stress endurance and catalytic vigour in Pseudomonas putida KT2440. Microb Cell Fact (2013) 0.89
Identification of novel factors involved in modulating motility of Salmonella enterica serotype typhimurium. PLoS One (2014) 0.88
SpoT-triggered stringent response controls usp gene expression in Pseudomonas aeruginosa. J Bacteriol (2008) 0.88
Transcription of the Escherichia coli fatty acid synthesis operon fabHDG is directly activated by FadR and inhibited by ppGpp. J Bacteriol (2013) 0.88
Manipulation of the carbon storage regulator system for metabolite remodeling and biofuel production in Escherichia coli. Microb Cell Fact (2012) 0.86
High coverage metabolomics analysis reveals phage-specific alterations to Pseudomonas aeruginosa physiology during infection. ISME J (2016) 0.86
Expanded role for the nitrogen assimilation control protein in the response of Klebsiella pneumoniae to nitrogen stress. J Bacteriol (2010) 0.84
The bacterial alarmone (p)ppGpp activates the type III secretion system in Erwinia amylovora. J Bacteriol (2015) 0.84
Stochastic switching induced adaptation in a starved Escherichia coli population. PLoS One (2011) 0.83
Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress. BMC Microbiol (2010) 0.83
Global Rsh-dependent transcription profile of Brucella suis during stringent response unravels adaptation to nutrient starvation and cross-talk with other stress responses. BMC Genomics (2013) 0.83
Effects of amino acid starvation on RelA diffusive behavior in live Escherichia coli. Mol Microbiol (2015) 0.83
Pleiotropic effects of a rel mutation on stress survival of Rhizobium etli CNPAF512. BMC Microbiol (2008) 0.82
DksA and (p)ppGpp have unique and overlapping contributions to Haemophilus ducreyi pathogenesis in humans. Infect Immun (2015) 0.81
SpdR, a response regulator required for stationary-phase induction of Caulobacter crescentus cspD. J Bacteriol (2010) 0.81
Ribosome•RelA structures reveal the mechanism of stringent response activation. Elife (2016) 0.81
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Involvement of cyclic AMP receptor protein in regulation of the rmf gene encoding the ribosome modulation factor in Escherichia coli. J Bacteriol (2013) 0.81
FtsH-mediated coordination of lipopolysaccharide biosynthesis in Escherichia coli correlates with the growth rate and the alarmone (p)ppGpp. J Bacteriol (2013) 0.81
A transcriptional "Scream" early response of E. coli prey to predatory invasion by Bdellovibrio. Curr Microbiol (2009) 0.81
Transcriptional regulator PerA influences biofilm-associated, platelet binding, and metabolic gene expression in Enterococcus faecalis. PLoS One (2012) 0.81
Transcriptome analysis of Enterococcus faecalis during mammalian infection shows cells undergo adaptation and exist in a stringent response state. PLoS One (2014) 0.80
Co-ordinated regulation of the extracytoplasmic stress factor, sigmaE, with other Escherichia coli sigma factors by (p)ppGpp and DksA may be achieved by specific regulation of individual holoenzymes. Mol Microbiol (2014) 0.80
Conditional Proteolysis of the Membrane Protein YfgM by the FtsH Protease Depends on a Novel N-terminal Degron. J Biol Chem (2015) 0.80
Global genome response of Escherichia coli O157∶H7 Sakai during dynamic changes in growth kinetics induced by an abrupt downshift in water activity. PLoS One (2014) 0.80
Phenotypic convergence in bacterial adaptive evolution to ethanol stress. BMC Evol Biol (2015) 0.80
Comparative proteomic analysis of Salmonella enterica serovar Typhimurium ppGpp-deficient mutant to identify a novel virulence protein required for intracellular survival in macrophages. BMC Microbiol (2010) 0.79
(p)ppGpp modulates cell size and the initiation of DNA replication in Caulobacter crescentus in response to a block in lipid biosynthesis. Microbiology (2015) 0.79
RelA inhibits Bacillus subtilis motility and chaining. J Bacteriol (2014) 0.79
A regulatory feedback loop between RpoS and SpoT supports the survival of Legionella pneumophila in water. Appl Environ Microbiol (2014) 0.79
Increased mutation frequency in redox-impaired Escherichia coli due to RelA- and RpoS-mediated repression of DNA repair. Appl Environ Microbiol (2010) 0.78
Genetics of Coxiella burnetii: on the path of specialization. Future Microbiol (2011) 0.78
Source and regulation of flux variability in Escherichia coli. BMC Syst Biol (2014) 0.78
Composition of the outgrowth medium modulates wake-up kinetics and ampicillin sensitivity of stringent and relaxed Escherichia coli. Sci Rep (2016) 0.78
Bacterial persistence is an active σS stress response to metabolic flux limitation. Mol Syst Biol (2016) 0.78
A protein constructed de novo enables cell growth by altering gene regulation. Proc Natl Acad Sci U S A (2016) 0.78
ppGpp metabolism is involved in heterocyst development in the cyanobacterium Anabaena sp. strain PCC 7120. J Bacteriol (2013) 0.77
A (p)ppGpp-null mutant of Haemophilus ducreyi is partially attenuated in humans due to multiple conflicting phenotypes. Infect Immun (2014) 0.77
Inactivation of Cell Division Protein FtsZ by SulA Makes Lon Indispensable for the Viability of a ppGpp0 Strain of Escherichia coli. J Bacteriol (2015) 0.77
The bacterial alarmone (p)ppGpp is required for virulence and controls cell size and survival of Pseudomonas syringae on plants. Environ Microbiol (2015) 0.77
Regulation of Growth, Cell Shape, Cell Division, and Gene Expression by Second Messengers (p)ppGpp and Cyclic Di-GMP in Mycobacterium smegmatis. J Bacteriol (2016) 0.77
Coxiella burnetii transcriptional analysis reveals serendipity clusters of regulation in intracellular bacteria. PLoS One (2010) 0.77
Dynamical Allocation of Cellular Resources as an Optimal Control Problem: Novel Insights into Microbial Growth Strategies. PLoS Comput Biol (2016) 0.76
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