Published in Arch Biochem Biophys on October 10, 2006
A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats. Am J Physiol Endocrinol Metab (2010) 1.10
Predictors of body composition and body energy changes in response to chronic overfeeding. Int J Obes (Lond) (2013) 0.84
HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression. J Inflamm (Lond) (2010) 0.80
Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss. Science (2002) 5.89
Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans. Cell Metab (2005) 3.47
Identification of transcribed sequences in Arabidopsis thaliana by using high-resolution genome tiling arrays. Proc Natl Acad Sci U S A (2005) 3.21
Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues. Proc Natl Acad Sci U S A (2002) 3.08
Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins. Nat Methods (2010) 2.77
Effects of diet and genetic background on sterol regulatory element-binding protein-1c, stearoyl-CoA desaturase 1, and the development of the metabolic syndrome. Diabetes (2005) 2.72
A combined approach to improving large-scale production of tobacco etch virus protease. Protein Expr Purif (2007) 2.62
Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver. Proc Natl Acad Sci U S A (2004) 2.48
Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells. Proc Natl Acad Sci U S A (2004) 2.41
Biochemical and physiological function of stearoyl-CoA desaturase. Am J Physiol Endocrinol Metab (2008) 2.28
Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia. J Lipid Res (2002) 2.28
Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. Cell Metab (2007) 2.25
Role of stearoyl-coenzyme A desaturase in regulating lipid metabolism. Curr Opin Lipidol (2008) 2.22
Stearoyl-CoA desaturase 1 gene expression is necessary for fructose-mediated induction of lipogenic gene expression by sterol regulatory element-binding protein-1c-dependent and -independent mechanisms. J Biol Chem (2004) 2.10
Polyunsaturated fatty acid regulation of genes of lipid metabolism. Annu Rev Nutr (2005) 2.07
Protocols for production of selenomethionine-labeled proteins in 2-L polyethylene terephthalate bottles using auto-induction medium. Protein Expr Purif (2005) 2.02
Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation. Mol Cell Biol (2006) 1.90
Genetic control of de novo lipogenesis: role in diet-induced obesity. Crit Rev Biochem Mol Biol (2010) 1.89
Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia. Arterioscler Thromb Vasc Biol (2008) 1.81
Stearoyl-CoA desaturase 1 deficiency elevates insulin-signaling components and down-regulates protein-tyrosine phosphatase 1B in muscle. Proc Natl Acad Sci U S A (2003) 1.71
Site and mechanism of leptin action in a rodent form of congenital lipodystrophy. J Clin Invest (2004) 1.71
Metabolomics reveals that hepatic stearoyl-CoA desaturase 1 downregulation exacerbates inflammation and acute colitis. Cell Metab (2008) 1.67
Targeting the stromal androgen receptor in primary prostate tumors at earlier stages. Proc Natl Acad Sci U S A (2008) 1.65
Auto-induction medium for the production of [U-15N]- and [U-13C, U-15N]-labeled proteins for NMR screening and structure determination. Protein Expr Purif (2005) 1.65
High-throughput purification and quality assurance of Arabidopsis thaliana proteins for eukaryotic structural genomics. J Struct Funct Genomics (2005) 1.65
Results from high-throughput DNA cloning of Arabidopsis thaliana target genes using site-specific recombination. J Struct Funct Genomics (2005) 1.64
Loss of stearoyl-CoA desaturase-1 improves insulin sensitivity in lean mice but worsens diabetes in leptin-deficient obese mice. Diabetes (2007) 1.59
Structure and mechanism of mouse cysteine dioxygenase. Proc Natl Acad Sci U S A (2006) 1.59
Effects of sterculic acid on stearoyl-CoA desaturase in differentiating 3T3-L1 adipocytes. Biochem Biophys Res Commun (2003) 1.59
Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat. J Biol Chem (2006) 1.52
Enhanced bacterial protein expression during auto-induction obtained by alteration of lac repressor dosage and medium composition. Biotechnol Prog (2007) 1.51
Structural consequences of effector protein complex formation in a diiron hydroxylase. Proc Natl Acad Sci U S A (2008) 1.47
Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle. Am J Physiol Endocrinol Metab (2004) 1.44
High efficiency single step production of expression plasmids from cDNA clones using the Flexi Vector cloning system. Protein Expr Purif (2005) 1.38
Role of stearoyl-coenzyme A desaturase in lipid metabolism. Prostaglandins Leukot Essent Fatty Acids (2003) 1.35
Characterization of the nitrosyl adduct of substrate-bound mouse cysteine dioxygenase by electron paramagnetic resonance: electronic structure of the active site and mechanistic implications. Biochemistry (2007) 1.34
Skin-specific deletion of stearoyl-CoA desaturase-1 alters skin lipid composition and protects mice from high fat diet-induced obesity. J Biol Chem (2009) 1.31
Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development. Proc Natl Acad Sci U S A (2005) 1.31
Polyunsaturated fatty acid regulation of gene expression. Nutr Rev (2004) 1.30
Lack of stearoyl-CoA desaturase 1 upregulates basal thermogenesis but causes hypothermia in a cold environment. J Lipid Res (2004) 1.30
Combined participation of hydroxylase active site residues and effector protein binding in a para to ortho modulation of toluene 4-monooxygenase regiospecificity. Biochemistry (2002) 1.29
Stearoyl-CoA desaturase-1 deficiency attenuates obesity and insulin resistance in leptin-resistant obese mice. Biochem Biophys Res Commun (2009) 1.27
Stearoyl-CoA desaturase and its relation to high-carbohydrate diets and obesity. Biochim Biophys Acta (2009) 1.27
Liver gene expression analysis reveals endoplasmic reticulum stress and metabolic dysfunction in SCD1-deficient mice fed a very low-fat diet. Physiol Genomics (2008) 1.26
Comparison of cell-based and cell-free protocols for producing target proteins from the Arabidopsis thaliana genome for structural studies. Proteins (2005) 1.26
Role of peroxisome proliferator-activated receptor {delta}/{beta} in hepatic metabolic regulation. J Biol Chem (2010) 1.26
Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c. Diabetes (2006) 1.25
Solution structures of spinach acyl carrier protein with decanoate and stearate. Biochemistry (2006) 1.23
Identification and characterization of murine SCD4, a novel heart-specific stearoyl-CoA desaturase isoform regulated by leptin and dietary factors. J Biol Chem (2003) 1.22
Reduced adiposity and liver steatosis by stearoyl-CoA desaturase deficiency are independent of peroxisome proliferator-activated receptor-alpha. J Biol Chem (2004) 1.22
Oligozoospermia with normal fertility in male mice lacking the androgen receptor in testis peritubular myoid cells. Proc Natl Acad Sci U S A (2006) 1.21
Identification of mouse palmitoyl-coenzyme A Delta9-desaturase. J Lipid Res (2006) 1.18
The role of stearoyl-CoA desaturase in the control of metabolism. Prostaglandins Leukot Essent Fatty Acids (2005) 1.18
Wheat germ cell-free translation, purification, and assembly of a functional human stearoyl-CoA desaturase complex. Protein Expr Purif (2008) 1.17
Stearoyl CoA desaturase 1: role in cellular inflammation and stress. Adv Nutr (2011) 1.16
Aerobic deconstruction of cellulosic biomass by an insect-associated Streptomyces. Sci Rep (2013) 1.16
The role of stearoyl-CoA desaturase in obesity, insulin resistance, and inflammation. Ann N Y Acad Sci (2011) 1.16
Stearoyl-CoA desaturase 1 deficiency increases insulin signaling and glycogen accumulation in brown adipose tissue. Am J Physiol Endocrinol Metab (2004) 1.15
Membrane topology of mouse stearoyl-CoA desaturase 1. J Biol Chem (2005) 1.14
Global gene expression patterns in Clostridium thermocellum as determined by microarray analysis of chemostat cultures on cellulose or cellobiose. Appl Environ Microbiol (2010) 1.14
Novel entries in a fungal biofilm matrix encyclopedia. MBio (2014) 1.13
Mitotic and neurogenic effects of dehydroepiandrosterone (DHEA) on human neural stem cell cultures derived from the fetal cortex. Proc Natl Acad Sci U S A (2004) 1.10
Cell-free translation of integral membrane proteins into unilamelar liposomes. Methods Enzymol (2009) 1.10
Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet. J Lipid Res (2006) 1.10
The role of stearoyl-CoA desaturase in body weight regulation. Trends Cardiovasc Med (2004) 1.08
Insight into the mechanism of aromatic hydroxylation by toluene 4-monooxygenase by use of specifically deuterated toluene and p-xylene. Proc Natl Acad Sci U S A (2003) 1.07
N-isotope effects on the Raman spectra of Fe(2)S(2) ferredoxin and Rieske ferredoxin: evidence for structural rigidity of metal sites. J Biol Inorg Chem (2002) 1.06
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome. Nat Struct Mol Biol (2013) 1.05
Loss of stearoyl-CoA desaturase 1 inhibits fatty acid oxidation and increases glucose utilization in the heart. Am J Physiol Endocrinol Metab (2007) 1.04
Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate. Arterioscler Thromb Vasc Biol (2009) 1.04
Stearoyl-CoA desaturase-1 and the metabolic syndrome. Curr Drug Targets Immune Endocr Metabol Disord (2003) 1.04
Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance. J Clin Invest (2006) 1.03
Parenteral nutrition impairs gut-associated lymphoid tissue and mucosal immunity by reducing lymphotoxin Beta receptor expression. Ann Surg (2006) 1.01
Inactivation of androgen receptor coregulator ARA55 inhibits androgen receptor activity and agonist effect of antiandrogens in prostate cancer cells. Proc Natl Acad Sci U S A (2003) 1.01
Lack of stearoyl-CoA desaturase-1 function induces a palmitoyl-CoA Delta6 desaturase and represses the stearoyl-CoA desaturase-3 gene in the preputial glands of the mouse. J Lipid Res (2002) 1.00
Spectroscopic and computational characterization of substrate-bound mouse cysteine dioxygenase: nature of the ferrous and ferric cysteine adducts and mechanistic implications. Biochemistry (2010) 0.99
Dietary cholesterol opposes PUFA-mediated repression of the stearoyl-CoA desaturase-1 gene by SREBP-1 independent mechanism. J Lipid Res (2002) 0.97
Stearoyl-CoA desaturase 1 deficiency increases CTP:choline cytidylyltransferase translocation into the membrane and enhances phosphatidylcholine synthesis in liver. J Biol Chem (2005) 0.97
Combined deletion of SCD1 from adipose tissue and liver does not protect mice from obesity. J Lipid Res (2012) 0.96
Small-scale, semi-automated purification of eukaryotic proteins for structure determination. J Struct Funct Genomics (2007) 0.96
Structures of proteins of biomedical interest from the Center for Eukaryotic Structural Genomics. J Struct Funct Genomics (2007) 0.96
Intestinal polymeric immunoglobulin receptor is affected by type and route of nutrition. JPEN J Parenter Enteral Nutr (2007) 0.95
Cellulolytic Streptomyces strains associated with herbivorous insects share a phylogenetically linked capacity to degrade lignocellulose. Appl Environ Microbiol (2014) 0.94
Stearoyl-coenzyme A desaturase 1, sterol regulatory element binding protein-1c and peroxisome proliferator-activated receptor-alpha: independent and interactive roles in the regulation of lipid metabolism. Curr Opin Clin Nutr Metab Care (2006) 0.94
Geometric and electronic structure studies of the binuclear nonheme ferrous active site of toluene-4-monooxygenase: parallels with methane monooxygenase and insight into the role of the effector proteins in O2 activation. J Am Chem Soc (2008) 0.94
Fluorescence anisotropy assay for proteolysis of specifically labeled fusion proteins. Anal Biochem (2005) 0.94
Structure of human J-type co-chaperone HscB reveals a tetracysteine metal-binding domain. J Biol Chem (2008) 0.94
Cell-free protein synthesis technology in NMR high-throughput structure determination. Methods Mol Biol (2010) 0.94
Structure of T4moC, the Rieske-type ferredoxin component of toluene 4-monooxygenase. Acta Crystallogr D Biol Crystallogr (2006) 0.93
The fate and intermediary metabolism of stearic acid. Lipids (2005) 0.93
Typing of Histoplasma capsulatum strains by fatty acid profile analysis. J Med Microbiol (2007) 0.93
X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv. Protein Sci (2005) 0.93
Role for threonine 201 in the catalytic cycle of the soluble diiron hydroxylase toluene 4-monooxygenase. Biochemistry (2009) 0.93
Polyunsaturated fatty acids do not activate AMP-activated protein kinase in mouse tissues. Biochem Biophys Res Commun (2005) 0.92
Injury stimulates an innate respiratory immunoglobulin a immune response in humans. J Trauma (2008) 0.92
Evidence that the anti-obesity effect of conjugated linoleic acid is independent of effects on stearoyl-CoA desaturase1 expression and enzyme activity. Biochem Biophys Res Commun (2004) 0.92
Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice. J Lipid Res (2010) 0.92
Role of stearoyl-CoA desaturase-1 in skin integrity and whole body energy balance. J Biol Chem (2013) 0.92
Crystallographic and catalytic studies of the peroxide-shunt reaction in a diiron hydroxylase. Biochemistry (2009) 0.92