Published in J Biol Chem on October 31, 2006
Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci (2010) 1.95
Structure and mechanism of protein stability sensors: chaperone activity of small heat shock proteins. Biochemistry (2009) 1.71
Detection and architecture of small heat shock protein monomers. PLoS One (2010) 0.99
Mechanism of insolubilization by a single-point mutation in alphaA-crystallin linked with hereditary human cataracts. Biochemistry (2008) 0.98
Sequence, structure, and dynamic determinants of Hsp27 (HspB1) equilibrium dissociation are encoded by the N-terminal domain. Biochemistry (2012) 0.95
Alpha crystallin: the quest for a homogeneous quaternary structure. Exp Eye Res (2008) 0.93
Structure and orientation of T4 lysozyme bound to the small heat shock protein alpha-crystallin. J Mol Biol (2007) 0.91
Free-solution label-free detection of alpha-crystallin chaperone interactions by back-scattering interferometry. Anal Chem (2009) 0.90
Crystal structure of an activated variant of small heat shock protein Hsp16.5. Biochemistry (2012) 0.89
Deletion of (54)FLRAPSWF(61) residues decreases the oligomeric size and enhances the chaperone function of alphaB-crystallin. Biochemistry (2009) 0.86
Cryoelectron microscopy analysis of small heat shock protein 16.5 (Hsp16.5) complexes with T4 lysozyme reveals the structural basis of multimode binding. J Biol Chem (2012) 0.86
Role of alphaBI5 and alphaBT162 residues in subunit interaction during oligomerization of alphaB-crystallin. Mol Vis (2008) 0.81
Characterization of Mutants of Human Small Heat Shock Protein HspB1 Carrying Replacements in the N-Terminal Domain and Associated with Hereditary Motor Neuron Diseases. PLoS One (2015) 0.80
Changes in the quaternary structure and function of MjHSP16.5 attributable to deletion of the IXI motif and introduction of the substitution, R107G, in the α-crystallin domain. Philos Trans R Soc Lond B Biol Sci (2013) 0.78
Species-Specific Structural and Functional Divergence of α-Crystallins: Zebrafish αBa- and Rodent αA(ins)-Crystallin Encode Activated Chaperones. Biochemistry (2015) 0.78
Designing and defining dynamic protein cage nanoassemblies in solution. Sci Adv (2016) 0.75
Tilt-pair analysis of images from a range of different specimens in single-particle electron cryomicroscopy. J Mol Biol (2011) 3.16
Protein structure determination using long-distance constraints from double-quantum coherence ESR: study of T4 lysozyme. J Am Chem Soc (2002) 2.48
Structural basis of energy transduction in the transport cycle of MsbA. Science (2005) 2.26
Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters. Nat Struct Mol Biol (2010) 2.20
Elucidating the ticking of an in vitro circadian clockwork. PLoS Biol (2007) 2.19
Cryo-EM structure of the DNA-dependent protein kinase catalytic subunit at subnanometer resolution reveals alpha helices and insight into DNA binding. Structure (2008) 2.17
Crystal structure of human adenovirus at 3.5 A resolution. Science (2010) 2.17
Coagulation factor X activates innate immunity to human species C adenovirus. Science (2012) 2.09
Visualization of alpha-helices in a 6-angstrom resolution cryoelectron microscopy structure of adenovirus allows refinement of capsid protein assignments. J Virol (2006) 1.96
Structure and mechanism of protein stability sensors: chaperone activity of small heat shock proteins. Biochemistry (2009) 1.71
Analysis of KaiA-KaiC protein interactions in the cyano-bacterial circadian clock using hybrid structural methods. EMBO J (2006) 1.59
Conformational cycle of the ABC transporter MsbA in liposomes: detailed analysis using double electron-electron resonance spectroscopy. J Mol Biol (2009) 1.56
RosettaEPR: an integrated tool for protein structure determination from sparse EPR data. J Struct Biol (2010) 1.50
Flexibility of the adenovirus fiber is required for efficient receptor interaction. J Virol (2003) 1.49
Increased sensitivity and extended range of distance measurements in spin-labeled membrane proteins: Q-band double electron-electron resonance and nanoscale bilayers. Biophys J (2010) 1.49
Mapping proximity within proteins using fluorescence spectroscopy. A study of T4 lysozyme showing that tryptophan residues quench bimane fluorescence. Biochemistry (2002) 1.40
Postentry neutralization of adenovirus type 5 by an antihexon antibody. J Virol (2004) 1.40
The cyanobacterial circadian system: from biophysics to bioevolution. Annu Rev Biophys (2011) 1.39
Cryoelectron microscopy imaging of recombinant and tissue derived vaults: localization of the MVP N termini and VPARP. J Mol Biol (2004) 1.39
Alternating access of the putative substrate-binding chamber in the ABC transporter MsbA. J Mol Biol (2009) 1.36
Engineering of vault nanocapsules with enzymatic and fluorescent properties. Proc Natl Acad Sci U S A (2005) 1.35
CryoEM structure at 9A resolution of an adenovirus vector targeted to hematopoietic cells. J Mol Biol (2005) 1.35
Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization. PLoS Pathog (2010) 1.34
Mechanism of chaperone function in small heat shock proteins: dissociation of the HSP27 oligomer is required for recognition and binding of destabilized T4 lysozyme. J Biol Chem (2004) 1.33
EM-fold: De novo folding of alpha-helical proteins guided by intermediate-resolution electron microscopy density maps. Structure (2009) 1.32
Structural insights into a circadian oscillator. Science (2008) 1.30
Adenovirus. Curr Top Microbiol Immunol (2010) 1.27
Cryo-electron microscopy structure of adenovirus type 2 temperature-sensitive mutant 1 reveals insight into the cell entry defect. J Virol (2009) 1.27
Mechanism of chaperone function in small heat-shock proteins. Phosphorylation-induced activation of two-mode binding in alphaB-crystallin. J Biol Chem (2003) 1.20
Structural model of the circadian clock KaiB-KaiC complex and mechanism for modulation of KaiC phosphorylation. EMBO J (2008) 1.19
EM-fold: de novo atomic-detail protein structure determination from medium-resolution density maps. Structure (2012) 1.15
Binding of destabilized betaB2-crystallin mutants to alpha-crystallin: the role of a folding intermediate. J Biol Chem (2004) 1.13
Targeting vault nanoparticles to specific cell surface receptors. ACS Nano (2009) 1.13
Hybrid approaches: applying computational methods in cryo-electron microscopy. Curr Opin Struct Biol (2009) 1.11
Mechanism of chaperone function in small heat shock proteins. Two-mode binding of the excited states of T4 lysozyme mutants by alphaA-crystallin. J Biol Chem (2002) 1.10
Cryo-electron microscopy structure of an adenovirus-integrin complex indicates conformational changes in both penton base and integrin. J Virol (2009) 1.08
Structure, dynamics, and substrate-induced conformational changes of the multidrug transporter EmrE in liposomes. J Biol Chem (2010) 1.08
Structure of the substrate binding pocket of the multidrug transporter EmrE: site-directed spin labeling of transmembrane segment 1. Biochemistry (2003) 1.07
HIV antigen incorporation within adenovirus hexon hypervariable 2 for a novel HIV vaccine approach. PLoS One (2010) 1.07
Combined SAXS/EM based models of the S. elongatus post-translational circadian oscillator and its interactions with the output His-kinase SasA. PLoS One (2011) 1.05
Structural refinement from restrained-ensemble simulations based on EPR/DEER data: application to T4 lysozyme. J Phys Chem B (2013) 1.04
Algorithm for selection of optimized EPR distance restraints for de novo protein structure determination. J Struct Biol (2010) 1.02
CryoEM and molecular dynamics of the circadian KaiB-KaiC complex indicates that KaiB monomers interact with KaiC and block ATP binding clefts. J Mol Biol (2013) 1.00
Role of sequence bias in the topology of the multidrug transporter EmrE. Biochemistry (2008) 1.00
Mapping daunorubicin-binding Sites in the ATP-binding cassette transporter MsbA using site-specific quenching by spin labels. J Biol Chem (2009) 0.99
Human rotavirus VP6-specific antibodies mediate intracellular neutralization by binding to a quaternary structure in the transcriptional pore. PLoS One (2013) 0.98
A Script-Assisted Microscopy (SAM) package to improve data acquisition rates on FEI Tecnai electron microscopes equipped with Gatan CCD cameras. J Struct Biol (2008) 0.96
Sequence, structure, and dynamic determinants of Hsp27 (HspB1) equilibrium dissociation are encoded by the N-terminal domain. Biochemistry (2012) 0.95
BCL::EM-Fit: rigid body fitting of atomic structures into density maps using geometric hashing and real space refinement. J Struct Biol (2011) 0.95
Structure of flexible filamentous plant viruses. J Virol (2008) 0.95
Specificity of alphaA-crystallin binding to destabilized mutants of betaB1-crystallin. FEBS Lett (2007) 0.94
Structure of human adenovirus. Curr Opin Virol (2012) 0.91
Ab initio protein modeling into CryoEM density maps using EM-Fold. Biopolymers (2012) 0.88
Atomic models by cryo-EM and site-directed spin labeling: application to the N-terminal region of Hsp16.5. Structure (2005) 0.88
Direct observation of T4 lysozyme hinge-bending motion by fluorescence correlation spectroscopy. Biophys J (2012) 0.87
An intrinsically disordered region of the adenovirus capsid is implicated in neutralization by human alpha defensin 5. PLoS One (2013) 0.87
RosettaEPR: rotamer library for spin label structure and dynamics. PLoS One (2013) 0.87
Analysis of betaB1-crystallin unfolding equilibrium by spin and fluorescence labeling: evidence of a dimeric intermediate. FEBS Lett (2007) 0.86
Cryoelectron microscopy analysis of small heat shock protein 16.5 (Hsp16.5) complexes with T4 lysozyme reveals the structural basis of multimode binding. J Biol Chem (2012) 0.86
A common structure for the potexviruses. Virology (2012) 0.85
Cataract-linked γD-crystallin mutants have weak affinity to lens chaperones α-crystallins. FEBS Lett (2012) 0.84
Advanced generation adenoviral virotherapy agents embody enhanced potency based upon CAR-independent tropism. Clin Cancer Res (2006) 0.84
Studies of the mechanistic details of the pH-dependent association of botulinum neurotoxin with membranes. J Biol Chem (2011) 0.83
Na⁺-substrate coupling in the multidrug antiporter norm probed with a spin-labeled substrate. Biochemistry (2013) 0.83
Disulfide cross-links in the interaction of a cataract-linked alphaA-crystallin mutant with betaB1-crystallin. FEBS Lett (2008) 0.82
Coagulation factor binding orientation and dimerization may influence infectivity of adenovirus-coagulation factor complexes. J Virol (2013) 0.79
Differential accessibility of a rotavirus VP6 epitope in trimers comprising type I, II, or III channels as revealed by binding of a human rotavirus VP6-specific antibody. J Virol (2013) 0.78
CryoEM visualization of an adenovirus capsid-incorporated HIV antigen. PLoS One (2012) 0.77
Barley stripe mosaic virus: structure and relationship to the tobamoviruses. Virology (2013) 0.77
Environmentally responsive self-assembly of mixed poly(tert-butyl acrylate)-polystyrene brush-grafted silica nanoparticles in selective polymer matrices. Soft Matter (2015) 0.77
Computational determination of the orientation of a heat repeat-like domain of DNA-PKcs. Comput Biol Chem (2012) 0.75
Polymer Structure and Conformation Alter the Antigenicity of Virus-like Particle-Polymer Conjugates. J Am Chem Soc (2017) 0.75