Published in Haematologica on November 01, 2006
Methemoglobinemia in a young man. Tex Heart Inst J (2008) 1.19
Molecular basis of two novel mutations found in type I methemoglobinemia. Blood Cells Mol Dis (2011) 0.82
Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood (2006) 8.56
Essential role for Nix in autophagic maturation of erythroid cells. Nature (2008) 6.49
Genetic evidence for high-altitude adaptation in Tibet. Science (2010) 5.37
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia. Nat Genet (2002) 4.06
JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia. Blood (2005) 3.24
Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera. Exp Hematol (2002) 2.77
Polycythemia vera is not initiated by JAK2V617F mutation. Exp Hematol (2007) 2.75
Somatic HIF2A gain-of-function mutations in paraganglioma with polycythemia. N Engl J Med (2012) 2.74
Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development. J Biol Chem (2006) 2.39
Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells. J Immunol (2010) 2.35
Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors. Blood (2004) 2.27
Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload. Blood (2004) 2.12
X-linked clonality testing: interpretation and limitations. Blood (2007) 2.04
Endothelin-1, vascular endothelial growth factor and systolic pulmonary artery pressure in patients with Chuvash polycythemia. Haematologica (2006) 2.04
Congenital polycythemias/erythrocytoses. Haematologica (2005) 1.99
Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis. Exp Hematol (2007) 1.98
Hematopoiesis is not clonal in healthy elderly women. Blood (2008) 1.95
Mutations in the VHL gene in sporadic apparently congenital polycythemia. Blood (2002) 1.65
Genetic association analysis of chronic mountain sickness in an Andean high-altitude population. Haematologica (2005) 1.59
Quantification of fibrosis and osteosclerosis in myeloproliferative neoplasms: a computer-assisted image study. Leuk Res (2010) 1.54
Clonal hematopoiesis in familial polycythemia vera suggests the involvement of multiple mutational events in the early pathogenesis of the disease. Blood (2003) 1.52
Copper deficiency masquerading as myelodysplastic syndrome. Blood (2002) 1.51
Detection of JAK2 mutations in paraffin marrow biopsies by high resolution melting analysis: identification of L611S alone and in cis with V617F in polycythemia vera. Leuk Lymphoma (2012) 1.46
Disruption of the NAD(P)H:quinone oxidoreductase 1 (NQO1) gene in mice causes myelogenous hyperplasia. Cancer Res (2002) 1.45
Aberrant expression of microRNA in polycythemia vera. Haematologica (2008) 1.37
The evolution of cellular deficiency in GATA2 mutation. Blood (2013) 1.36
Constitutive mobilization of CD34+ cells into the peripheral blood in idiopathic myelofibrosis may be due to the action of a number of proteases. Blood (2005) 1.35
Concordance of assays designed for the quantification of JAK2V617F: a multicenter study. Haematologica (2008) 1.33
Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation. J Biol Chem (2007) 1.32
New syndrome of paraganglioma and somatostatinoma associated with polycythemia. J Clin Oncol (2013) 1.32
Vascular complications in Chuvash polycythemia. Semin Thromb Hemost (2006) 1.29
Endemic polycythemia in Russia: mutation in the VHL gene. Blood Cells Mol Dis (2002) 1.28
Structural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motif. J Biol Chem (2004) 1.28
In vitro expansion of erythroid progenitors from polycythemia vera patients leads to decrease in JAK2 V617F allele. Exp Hematol (2007) 1.26
Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res (2006) 1.24
Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice. Development (2004) 1.21
Genetic determinants of Tibetan high-altitude adaptation. Hum Genet (2011) 1.21
Lessons from familial myeloproliferative disorders. Semin Hematol (2005) 1.20
Targeting signal transducer and activator of transcription 3 with G-quartet oligonucleotides: a potential novel therapy for head and neck cancer. Mol Cancer Ther (2006) 1.16
Elevated tricuspid regurgitation velocity and decline in exercise capacity over 22 months of follow up in children and adolescents with sickle cell anemia. Haematologica (2010) 1.16
Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice. Development (2004) 1.14
The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation. Cancer Sci (2008) 1.14
Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis. Cancer Res (2005) 1.13
A novel EPAS1/HIF2A germline mutation in a congenital polycythemia with paraganglioma. J Mol Med (Berl) (2012) 1.13
Triterpenoid electrophiles (avicins) activate the innate stress response by redox regulation of a gene battery. J Clin Invest (2004) 1.12
Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity. J Biol Chem (2002) 1.11
Mutations of von Hippel-Lindau tumor-suppressor gene and congenital polycythemia. Am J Hum Genet (2003) 1.10
Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas. Blood (2013) 1.07
The worldwide distribution of the VHL 598C>T mutation indicates a single founding event. Blood (2003) 1.07
Divalent metal transporter 1. Hematology (2005) 1.07
Angiogenic and inflammatory markers of cardiopulmonary changes in children and adolescents with sickle cell disease. PLoS One (2009) 1.07
Hypoxia. 5. Hypoxia and hematopoiesis. Am J Physiol Cell Physiol (2011) 1.07
miR-451 enhances erythroid differentiation in K562 cells. Leuk Lymphoma (2010) 1.06
Interim analysis of safety and efficacy of ruxolitinib in patients with myelofibrosis and low platelet counts. J Hematol Oncol (2013) 1.05
Sickle cell disease resulting from uniparental disomy in a child who inherited sickle cell trait. Blood (2010) 1.04
Role of JAK/STAT pathway in IL-6-induced activation of vascular smooth muscle cells. Am J Nephrol (2004) 1.03
Inhibition of Stat3 activation and tumor growth suppression of non-small cell lung cancer by G-quartet oligonucleotides. Int J Oncol (2007) 1.02
Treatment target in polycythemia vera. N Engl J Med (2013) 1.02
The phenotype of polycythemia due to Croatian homozygous VHL (571C>G:H191D) mutation is different from that of Chuvash polycythemia (VHL 598C>T:R200W). Haematologica (2013) 0.97
New onset of myelofibrosis in association with pulmonary arterial hypertension. Ann Intern Med (2005) 0.97
Familial polycythemia caused by a novel mutation in the beta globin gene: essential role of P50 in evaluation of familial polycythemia. Int J Med Sci (2007) 0.96
Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression. Blood (2011) 0.94
Pulmonary artery pressure and iron deficiency in patients with upregulation of hypoxia sensing due to homozygous VHL(R200W) mutation (Chuvash polycythemia). Haematologica (2011) 0.94
Erythropoiesis in polycythemia vera is hyper-proliferative and has accelerated maturation. Blood Cells Mol Dis (2009) 0.93
Allogeneic haematopoietic cell transplantation for myelofibrosis in 30 patients 60-78 years of age. Br J Haematol (2011) 0.93
Metabolic insight into mechanisms of high-altitude adaptation in Tibetans. Mol Genet Metab (2012) 0.93
Methylation of AR locus does not always reflect X chromosome inactivation state. Blood (2012) 0.93
Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease. Circulation (2014) 0.92
Convergent mechanisms of somatic mutations in polycythemia vera. Discov Med (2011) 0.91
Severe hypochromic microcytic anemia caused by a congenital defect of the iron transport pathway in erythroid cells. Blood (2004) 0.91
Regulation of ferrochelatase gene expression by hypoxia. Life Sci (2004) 0.90
Computational study on mechanism of G-quartet oligonucleotide T40214 selectively targeting Stat3. J Comput Aided Mol Des (2007) 0.90
Philadelphia chromosome-negative myeloproliferative disorders: biology and treatment. Biol Blood Marrow Transplant (2007) 0.90
Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism. J Mol Med (Berl) (2012) 0.90
Novel homozygous VHL mutation in exon 2 is associated with congenital polycythemia but not with cancer. Blood (2013) 0.89
The heterozygote advantage of the Chuvash polycythemia VHLR200W mutation may be protection against anemia. Haematologica (2011) 0.89
Congenital polycythemia with homozygous and heterozygous mutations of von Hippel-Lindau gene: five new Caucasian patients. Haematologica (2005) 0.88
Imatinib effect on growth and signal transduction in polycythemia vera. Exp Hematol (2007) 0.87
Combined treatment targeting HIF-1α and Stat3 is a potent strategy for prostate cancer therapy. Prostate (2011) 0.87
The constitutive mobilization of bone marrow-repopulating cells into the peripheral blood in idiopathic myelofibrosis. Blood (2004) 0.86
JAK2 kinase inhibitors and myeloproliferative disorders. Curr Opin Hematol (2010) 0.86
The HIF2A gene in familial erythrocytosis. N Engl J Med (2008) 0.86
Association of G6PD with lower haemoglobin concentration but not increased haemolysis in patients with sickle cell anaemia. Br J Haematol (2010) 0.86
Heterogeneity of the molecular biology of methemoglobinemia: a study of eight consecutive patients. Haematologica (2005) 0.85
DMT1 mutation: response of anemia to darbepoetin administration and implications for iron homeostasis. Blood (2006) 0.85
A quantitative allele-specific PCR test for the BRAF V600E mutation using a single heterozygous control plasmid for quantitation: a model for qPCR testing without standard curves. J Mol Diagn (2013) 0.85
EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors. PLoS One (2010) 0.85
HIF-mediated increased ROS from reduced mitophagy and decreased catalase causes neocytolysis. J Mol Med (Berl) (2015) 0.84
Oxygen-dependent regulation of erythropoiesis. Methods Enzymol (2004) 0.84
Erythropoietin receptor signaling regulates both erythropoiesis and megakaryopoiesis in vivo. Blood Cells Mol Dis (2009) 0.84
Molecular heterogeneity of glucose-6-phosphate dehydrogenase deficiency in Gaza Strip Palestinians. Blood Cells Mol Dis (2012) 0.84
Genetic adaptation to extreme hypoxia: study of high-altitude pulmonary edema in a three-generation Han Chinese family. Blood Cells Mol Dis (2009) 0.84
Increased size of solid organs in patients with Chuvash polycythemia and in mice with altered expression of HIF-1alpha and HIF-2alpha. J Mol Med (Berl) (2010) 0.84
Elevated homocysteine, glutathione and cysteinylglycine concentrations in patients homozygous for the Chuvash polycythemia VHL mutation. Haematologica (2008) 0.84
T40214/PEI complex: a potent therapeutics for prostate cancer that targets STAT3 signaling. Prostate (2008) 0.84