Published in Biol Blood Marrow Transplant on January 01, 2007
Reversible Secondary Myelofibrosis or Clonal Myeloproliferative Disorder | NCT00722254
In vitro megakaryocyte differentiation and proplatelet formation in Ph-negative classical myeloproliferative neoplasms: distinct patterns in the different clinical phenotypes. PLoS One (2011) 1.15
Characterization of a highly effective protein substrate for analysis of JAK2(V617F) Activity. Exp Hematol (2007) 0.94
MPD-RC 101 prospective study of reduced-intensity allogeneic hematopoietic stem cell transplantation in patients with myelofibrosis. Blood (2014) 0.90
Primary thrombocytosis in children. Haematologica (2014) 0.89
Allogeneic stem cell transplantation for myelofibrosis with leukemic transformation. Biol Blood Marrow Transplant (2010) 0.87
An update on allogeneic hematopoietic progenitor cell transplantation for myeloproliferative neoplasms in the era of tyrosine kinase inhibitors. Bone Marrow Transplant (2014) 0.81
Optimizing reduced-intensity conditioning regimens for myeloproliferative neoplasms. Expert Rev Hematol (2010) 0.78
Homoharringtonine is an effective therapy for patients with polycythemia vera or essential thrombocythemia who have failed or were intolerant to hydroxycarbamide or interferon-α therapy. Int J Clin Oncol (2012) 0.75
Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals. Blood (2006) 8.56
Essential role for Nix in autophagic maturation of erythroid cells. Nature (2008) 6.49
Genetic evidence for high-altitude adaptation in Tibet. Science (2010) 5.37
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia. Nat Genet (2002) 4.06
JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia. Blood (2005) 3.24
Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera. Exp Hematol (2002) 2.77
Polycythemia vera is not initiated by JAK2V617F mutation. Exp Hematol (2007) 2.75
Somatic HIF2A gain-of-function mutations in paraganglioma with polycythemia. N Engl J Med (2012) 2.74
Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development. J Biol Chem (2006) 2.39
Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors. Blood (2004) 2.27
Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload. Blood (2004) 2.12
X-linked clonality testing: interpretation and limitations. Blood (2007) 2.04
Endothelin-1, vascular endothelial growth factor and systolic pulmonary artery pressure in patients with Chuvash polycythemia. Haematologica (2006) 2.04
Multipotent mesenchymal stem cells with immunosuppressive activity can be easily isolated from dental pulp. Transplantation (2005) 2.02
Congenital polycythemias/erythrocytoses. Haematologica (2005) 1.99
Regulated expression of microRNAs in normal and polycythemia vera erythropoiesis. Exp Hematol (2007) 1.98
Hematopoiesis is not clonal in healthy elderly women. Blood (2008) 1.95
Mutations in the VHL gene in sporadic apparently congenital polycythemia. Blood (2002) 1.65
Genetic association analysis of chronic mountain sickness in an Andean high-altitude population. Haematologica (2005) 1.59
Quantification of fibrosis and osteosclerosis in myeloproliferative neoplasms: a computer-assisted image study. Leuk Res (2010) 1.54
Clonal hematopoiesis in familial polycythemia vera suggests the involvement of multiple mutational events in the early pathogenesis of the disease. Blood (2003) 1.52
Copper deficiency masquerading as myelodysplastic syndrome. Blood (2002) 1.51
Detection of JAK2 mutations in paraffin marrow biopsies by high resolution melting analysis: identification of L611S alone and in cis with V617F in polycythemia vera. Leuk Lymphoma (2012) 1.46
Aberrant expression of microRNA in polycythemia vera. Haematologica (2008) 1.37
The evolution of cellular deficiency in GATA2 mutation. Blood (2013) 1.36
Constitutive mobilization of CD34+ cells into the peripheral blood in idiopathic myelofibrosis may be due to the action of a number of proteases. Blood (2005) 1.35
Concordance of assays designed for the quantification of JAK2V617F: a multicenter study. Haematologica (2008) 1.33
Endogenous erythropoietin signaling is required for normal neural progenitor cell proliferation. J Biol Chem (2007) 1.32
New syndrome of paraganglioma and somatostatinoma associated with polycythemia. J Clin Oncol (2013) 1.32
Vascular complications in Chuvash polycythemia. Semin Thromb Hemost (2006) 1.29
Endemic polycythemia in Russia: mutation in the VHL gene. Blood Cells Mol Dis (2002) 1.28
In vitro expansion of erythroid progenitors from polycythemia vera patients leads to decrease in JAK2 V617F allele. Exp Hematol (2007) 1.26
Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res (2006) 1.24
Disruption of ferroportin 1 regulation causes dynamic alterations in iron homeostasis and erythropoiesis in polycythaemia mice. Development (2004) 1.21
Genetic determinants of Tibetan high-altitude adaptation. Hum Genet (2011) 1.21
Lessons from familial myeloproliferative disorders. Semin Hematol (2005) 1.20
Elevated tricuspid regurgitation velocity and decline in exercise capacity over 22 months of follow up in children and adolescents with sickle cell anemia. Haematologica (2010) 1.16
Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice. Development (2004) 1.14
A novel EPAS1/HIF2A germline mutation in a congenital polycythemia with paraganglioma. J Mol Med (Berl) (2012) 1.13
Mutations of von Hippel-Lindau tumor-suppressor gene and congenital polycythemia. Am J Hum Genet (2003) 1.10
Effects of extensive splenomegaly in patients with myelofibrosis undergoing a reduced intensity allogeneic stem cell transplantation. Br J Haematol (2008) 1.10
Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas. Blood (2013) 1.07
The worldwide distribution of the VHL 598C>T mutation indicates a single founding event. Blood (2003) 1.07
Divalent metal transporter 1. Hematology (2005) 1.07
Angiogenic and inflammatory markers of cardiopulmonary changes in children and adolescents with sickle cell disease. PLoS One (2009) 1.07
Fifty years of melphalan use in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant (2012) 1.07
Hypoxia. 5. Hypoxia and hematopoiesis. Am J Physiol Cell Physiol (2011) 1.07
miR-451 enhances erythroid differentiation in K562 cells. Leuk Lymphoma (2010) 1.06
Interim analysis of safety and efficacy of ruxolitinib in patients with myelofibrosis and low platelet counts. J Hematol Oncol (2013) 1.05
Sickle cell disease resulting from uniparental disomy in a child who inherited sickle cell trait. Blood (2010) 1.04
Treatment target in polycythemia vera. N Engl J Med (2013) 1.02
Role of plasmacytoid dendritic cells in immunity and tolerance after allogeneic hematopoietic stem cell transplantation. Transpl Immunol (2003) 1.01
Biology and treatment of primary myelofibrosis. Hematology Am Soc Hematol Educ Program (2007) 1.00
The phenotype of polycythemia due to Croatian homozygous VHL (571C>G:H191D) mutation is different from that of Chuvash polycythemia (VHL 598C>T:R200W). Haematologica (2013) 0.97
New onset of myelofibrosis in association with pulmonary arterial hypertension. Ann Intern Med (2005) 0.97
Familial polycythemia caused by a novel mutation in the beta globin gene: essential role of P50 in evaluation of familial polycythemia. Int J Med Sci (2007) 0.96
A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia. Haematologica (2006) 0.95
Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression. Blood (2011) 0.94
Pulmonary artery pressure and iron deficiency in patients with upregulation of hypoxia sensing due to homozygous VHL(R200W) mutation (Chuvash polycythemia). Haematologica (2011) 0.94
Erythropoiesis in polycythemia vera is hyper-proliferative and has accelerated maturation. Blood Cells Mol Dis (2009) 0.93
Allogeneic haematopoietic cell transplantation for myelofibrosis in 30 patients 60-78 years of age. Br J Haematol (2011) 0.93
Metabolic insight into mechanisms of high-altitude adaptation in Tibetans. Mol Genet Metab (2012) 0.93
Methylation of AR locus does not always reflect X chromosome inactivation state. Blood (2012) 0.93
Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease. Circulation (2014) 0.92
The dominant negative β isoform of the glucocorticoid receptor is uniquely expressed in erythroid cells expanded from polycythemia vera patients. Blood (2011) 0.92
Progress in haploidentical stem cell transplantation. Biol Blood Marrow Transplant (2011) 0.92
Convergent mechanisms of somatic mutations in polycythemia vera. Discov Med (2011) 0.91
Severe hypochromic microcytic anemia caused by a congenital defect of the iron transport pathway in erythroid cells. Blood (2004) 0.91
Regulation of ferrochelatase gene expression by hypoxia. Life Sci (2004) 0.90
CD11b+GR1+ myeloid cells secrete NGF and promote trigeminal ganglion neurite growth: implications for corneal nerve regeneration. Invest Ophthalmol Vis Sci (2013) 0.90
Plasmacytoid dendritic cells: do they have a role in immune responses after hematopoietic cell transplantation? Hum Immunol (2002) 0.90
Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism. J Mol Med (Berl) (2012) 0.90
Strength training following hematopoietic stem cell transplantation. Cancer Nurs (2011) 0.89
Familial childhood monosomy 7 and associated myelodysplasia. J Pediatr Hematol Oncol (2010) 0.89
Novel homozygous VHL mutation in exon 2 is associated with congenital polycythemia but not with cancer. Blood (2013) 0.89
The heterozygote advantage of the Chuvash polycythemia VHLR200W mutation may be protection against anemia. Haematologica (2011) 0.89
Congenital polycythemia with homozygous and heterozygous mutations of von Hippel-Lindau gene: five new Caucasian patients. Haematologica (2005) 0.88
Hematopoietic cell transplantation-specific comorbidity index predicts inpatient mortality and survival in patients who received allogeneic transplantation admitted to the intensive care unit. J Clin Oncol (2013) 0.88
Imatinib effect on growth and signal transduction in polycythemia vera. Exp Hematol (2007) 0.87
The constitutive mobilization of bone marrow-repopulating cells into the peripheral blood in idiopathic myelofibrosis. Blood (2004) 0.86
JAK2 kinase inhibitors and myeloproliferative disorders. Curr Opin Hematol (2010) 0.86
The HIF2A gene in familial erythrocytosis. N Engl J Med (2008) 0.86
Association of G6PD with lower haemoglobin concentration but not increased haemolysis in patients with sickle cell anaemia. Br J Haematol (2010) 0.86
EPO receptor gain-of-function causes hereditary polycythemia, alters CD34 cell differentiation and increases circulating endothelial precursors. PLoS One (2010) 0.85
Heterogeneity of the molecular biology of methemoglobinemia: a study of eight consecutive patients. Haematologica (2005) 0.85
DMT1 mutation: response of anemia to darbepoetin administration and implications for iron homeostasis. Blood (2006) 0.85
A quantitative allele-specific PCR test for the BRAF V600E mutation using a single heterozygous control plasmid for quantitation: a model for qPCR testing without standard curves. J Mol Diagn (2013) 0.85
HIF-mediated increased ROS from reduced mitophagy and decreased catalase causes neocytolysis. J Mol Med (Berl) (2015) 0.84
Molecular heterogeneity of glucose-6-phosphate dehydrogenase deficiency in Gaza Strip Palestinians. Blood Cells Mol Dis (2012) 0.84
Genetic adaptation to extreme hypoxia: study of high-altitude pulmonary edema in a three-generation Han Chinese family. Blood Cells Mol Dis (2009) 0.84
Oxygen-dependent regulation of erythropoiesis. Methods Enzymol (2004) 0.84
Erythropoietin receptor signaling regulates both erythropoiesis and megakaryopoiesis in vivo. Blood Cells Mol Dis (2009) 0.84
Increased size of solid organs in patients with Chuvash polycythemia and in mice with altered expression of HIF-1alpha and HIF-2alpha. J Mol Med (Berl) (2010) 0.84
Elevated homocysteine, glutathione and cysteinylglycine concentrations in patients homozygous for the Chuvash polycythemia VHL mutation. Haematologica (2008) 0.84
Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient-specific induced pluripotent stem cells. Stem Cells (2014) 0.83
Infectious complications in cord blood and T-cell depleted haploidentical stem cell transplantation. Am J Blood Res (2011) 0.83