Published in J Immunol on November 15, 2006
Phenotypical and functional specialization of FOXP3+ regulatory T cells. Nat Rev Immunol (2011) 4.29
The H19 non-coding RNA is essential for human tumor growth. PLoS One (2007) 3.75
Role of chemokines in tumor growth. Cancer Lett (2007) 3.36
CXCR4/CXCL12 axis in non small cell lung cancer (NSCLC) pathologic roles and therapeutic potential. Theranostics (2013) 1.35
Once a Treg, always a Treg? Immunol Rev (2014) 1.27
Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers. Breast Cancer Res (2011) 1.18
Targeting CXCL12/CXCR4 signaling with oncolytic virotherapy disrupts tumor vasculature and inhibits breast cancer metastases. Proc Natl Acad Sci U S A (2013) 1.17
Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors. Neuro Oncol (2008) 1.15
The intricate role of CXCR4 in cancer. Adv Cancer Res (2014) 1.04
Involvement of CCR6/CCL20/IL-17 axis in NSCLC disease progression. PLoS One (2011) 1.03
Home sweet home: the tumor microenvironment as a haven for regulatory T cells. Front Immunol (2013) 0.99
Nuclear localization of CXCR4 determines prognosis for colorectal cancer patients. Cancer Microenviron (2008) 0.92
The "Trojan Horse" approach to tumor immunotherapy: targeting the tumor microenvironment. J Immunol Res (2014) 0.88
Clinicopathological and therapeutic significance of CXCL12 expression in lung cancer. Int J Immunopathol Pharmacol (2010) 0.86
Examination of structure-activity relationship of viologen-based dendrimers as CXCR4 antagonists and gene carriers. Bioconjug Chem (2014) 0.83
Tumors as organs: biologically augmenting radiation therapy by inhibiting transforming growth factor β activity in carcinomas. Semin Radiat Oncol (2013) 0.83
Optimal population of FoxP3+ T cells in tumors requires an antigen priming-dependent trafficking receptor switch. PLoS One (2012) 0.80
Polymeric Plerixafor: effect of PEGylation on CXCR4 antagonism, cancer cell invasion, and DNA transfection. Pharm Res (2014) 0.79
Role of macrophages in malignancy. Ann Maxillofac Surg (2011) 0.77
The role of chemoattractant receptors in shaping the tumor microenvironment. Biomed Res Int (2014) 0.77
Harnessing immunosurveillance: current developments and future directions in cancer immunotherapy. Immunotargets Ther (2014) 0.75
Expression of the CXCR4 ligand SDF-1/CXCL12 is prognostically important for adenocarcinoma and large cell carcinoma of the lung. Virchows Arch (2016) 0.75
NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature (2004) 15.14
G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4. Nat Immunol (2002) 6.22
The sirtuin SIRT6 regulates lifespan in male mice. Nature (2012) 4.07
Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood (2004) 4.04
The H19 non-coding RNA is essential for human tumor growth. PLoS One (2007) 3.75
Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. FASEB J (2004) 2.94
CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow. Blood (2004) 2.84
Monoclonal antibody HCV-AbXTL68 in patients undergoing liver transplantation for HCV: results of a phase 2 randomized study. Liver Transpl (2006) 2.12
Phase I/II trial of intravenous NDV-HUJ oncolytic virus in recurrent glioblastoma multiforme. Mol Ther (2005) 1.85
Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis. Eur J Gastroenterol Hepatol (2009) 1.85
Small interfering RNA inhibits hepatitis B virus replication in mice. Mol Ther (2003) 1.76
A streptococcal protease that degrades CXC chemokines and impairs bacterial clearance from infected tissues. EMBO J (2006) 1.69
Stable genetic modification of human embryonic stem cells by lentiviral vectors. Mol Ther (2003) 1.68
CXCL12 expression by invasive trophoblasts induces the specific migration of CD16- human natural killer cells. Blood (2003) 1.62
Pulmonary epithelioid hemangioendothelioma. Isr Med Assoc J (2011) 1.61
MicroRNA expression patterns and function in endodermal differentiation of human embryonic stem cells. PLoS One (2008) 1.56
Paediatric and adolescent elevated conjunctival lesions in the plical area: lymphoma or reactive lymphoid hyperplasia? Br J Ophthalmol (2013) 1.49
In vitro and in vivo therapeutic efficacy of CXCR4 antagonist BKT140 against human non-small cell lung cancer. J Thorac Cardiovasc Surg (2012) 1.48
IL-6/IL-6R axis plays a critical role in acute kidney injury. J Am Soc Nephrol (2008) 1.48
Unique SDF-1-induced activation of human precursor-B ALL cells as a result of altered CXCR4 expression and signaling. Blood (2003) 1.48
In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli. Clin Exp Pharmacol Physiol (2013) 1.41
The oncofetal H19 RNA connection: hypoxia, p53 and cancer. Biochim Biophys Acta (2010) 1.41
Gene transfer to chicks using lentiviral vectors administered via the embryonic chorioallantoic membrane. PLoS One (2012) 1.40
Comprehensive gene and microRNA expression profiling reveals a role for microRNAs in human liver development. PLoS One (2009) 1.37
Atypical PKC-zeta regulates SDF-1-mediated migration and development of human CD34+ progenitor cells. J Clin Invest (2005) 1.36
CXCR4/CXCL12 axis in non small cell lung cancer (NSCLC) pathologic roles and therapeutic potential. Theranostics (2013) 1.35
The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers. PLoS One (2009) 1.29
A pivotal role of cyclic AMP-responsive element binding protein in tumor progression. Cancer Res (2004) 1.29
Mutant KRAS is a druggable target for pancreatic cancer. Proc Natl Acad Sci U S A (2013) 1.26
Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks. Proc Natl Acad Sci U S A (2010) 1.26
Diagnosis and management of Rosai-Dorfman disease involving the central nervous system. Neurol Res (2010) 1.23
Human CD34(+)CXCR4(-) sorted cells harbor intracellular CXCR4, which can be functionally expressed and provide NOD/SCID repopulation. Blood (2002) 1.23
Involvement of the CXCL12/CXCR4 pathway in the advanced liver disease that is associated with hepatitis C virus or hepatitis B virus. Eur J Immunol (2004) 1.20
IFN-gamma acts on T cells to induce NK cell mobilization and accumulation in target organs. J Immunol (2006) 1.19
A plant-derived recombinant human glucocerebrosidase enzyme--a preclinical and phase I investigation. PLoS One (2009) 1.19
Increased microRNA activity in human cancers. PLoS One (2009) 1.18
Involvement of the CXCL12/CXCR4 pathway in the recovery of skin following burns. J Invest Dermatol (2006) 1.17
Gene therapy platform for bone regeneration using an exogenously regulated, AAV-2-based gene expression system. Mol Ther (2004) 1.17
Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout mice. Cancer Res (2006) 1.16
Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression. Cancer Res (2010) 1.16
64Cu-AMD3100--a novel imaging agent for targeting chemokine receptor CXCR4. Bioorg Med Chem (2009) 1.16
Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment. J Clin Invest (2014) 1.16
Role of caspase-8 in hepatocyte response to infection and injury in mice. Hepatology (2007) 1.15
Chemokines in hepatitis C virus infection: pathogenesis, prognosis and therapeutics. Cytokine (2007) 1.14
Involvement of CXCR4 and IL-2 in the homing and retention of human NK and NK T cells to the bone marrow and spleen of NOD/SCID mice. Blood (2003) 1.13
PET of tumor CXCR4 expression with 4-18F-T140. J Nucl Med (2010) 1.13
Minimally invasive procedures for diagnosis of traumatic right diaphragmatic tears: a method for correct diagnosis in selected patients. Am Surg (2007) 1.11
Lentiviral vectors harboring a dual-gene system allow high and homogeneous transgene expression in selected polyclonal human embryonic stem cells. Mol Ther (2006) 1.10
Femtosecond infrared laser-an efficient and safe in vivo gene delivery system for prolonged expression. Mol Ther (2003) 1.08
MicroPET imaging of integrin αvβ3 expressing tumors using 89Zr-RGD peptides. Mol Imaging Biol (2011) 1.08
Interaction between neoplastic cells and cancer-associated fibroblasts through the CXCL12/CXCR4 axis: role in non-small cell lung cancer tumor proliferation. J Thorac Cardiovasc Surg (2011) 1.08
CXCR4 antagonist 4F-benzoyl-TN14003 inhibits leukemia and multiple myeloma tumor growth. Exp Hematol (2010) 1.07
Interaction between CXCR4 and CCL20 pathways regulates tumor growth. PLoS One (2009) 1.07
IFN-gamma treatment at early stages of influenza virus infection protects mice from death in a NK cell-dependent manner. J Interferon Cytokine Res (2010) 1.07
Toll-like receptor 3 signaling attenuates liver regeneration. Hepatology (2009) 1.06
The haematopoietic specific signal transducer Vav1 is expressed in a subset of human neuroblastomas. J Pathol (2003) 1.06
Rapid and simple one-step F-18 labeling of peptides. Bioconjug Chem (2011) 1.06
PET imaging of CXCR4 using copper-64 labeled peptide antagonist. Theranostics (2011) 1.05
Chemokines and chemokine receptors in stem cell circulation. Front Biosci (2008) 1.04
Involvement of CCR6/CCL20/IL-17 axis in NSCLC disease progression. PLoS One (2011) 1.03
Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment. Exp Hematol (2011) 1.03
Potential of CXCR4 antagonists for the treatment of metastatic lung cancer. Expert Rev Anticancer Ther (2011) 1.03
A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion. Crit Care (2006) 1.03
Epithelial cell apoptosis by fas ligand-positive myofibroblasts in lung fibrosis. Am J Respir Cell Mol Biol (2006) 1.01
Molecular mechanisms of liver carcinogenesis in the mdr2-knockout mice. Mol Cancer Res (2007) 0.99
The hepatitis C virus (HCV)-Trimera mouse: a model for evaluation of agents against HCV. J Infect Dis (2002) 0.99
Temporary regression of Merkel cell carcinoma metastases after cessation of cyclosporine. Transplantation (2002) 0.99
Recruited macrophages control dissemination of group A Streptococcus from infected soft tissues. J Immunol (2011) 0.98
TLR3 signaling in a hepatoma cell line is skewed towards apoptosis. J Cell Biochem (2007) 0.98