Published in Neuropharmacology on November 02, 2006
The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia. Trends Pharmacol Sci (2009) 3.06
JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain. J Neurosci (2009) 2.64
Glia and pain: is chronic pain a gliopathy? Pain (2013) 2.21
TNF-alpha and neuropathic pain--a review. J Neuroinflammation (2010) 1.68
Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy. Mol Pain (2011) 1.66
"Listening" and "talking" to neurons: implications of immune activation for pain control and increasing the efficacy of opioids. Brain Res Rev (2007) 1.62
Emerging role of Toll-like receptors in the control of pain and itch. Neurosci Bull (2012) 1.60
Emerging targets in neuroinflammation-driven chronic pain. Nat Rev Drug Discov (2014) 1.57
Neuropathic pain and cytokines: current perspectives. J Pain Res (2013) 1.26
Activation of JNK pathway in persistent pain. Neurosci Lett (2008) 1.19
Microglia and spinal cord synaptic plasticity in persistent pain. Neural Plast (2013) 1.17
Does dexmedetomidine as a neuraxial adjuvant facilitate better anesthesia and analgesia? A systematic review and meta-analysis. PLoS One (2014) 1.06
Hyperalgesia by synaptic long-term potentiation (LTP): an update. Curr Opin Pharmacol (2011) 1.01
Chronic cannabinoid receptor 2 activation reverses paclitaxel neuropathy without tolerance or cannabinoid receptor 1-dependent withdrawal. Biol Psychiatry (2014) 0.98
Maladaptive spinal plasticity opposes spinal learning and recovery in spinal cord injury. Front Physiol (2012) 0.98
Maximum-entropy network analysis reveals a role for tumor necrosis factor in peripheral nerve development and function. Proc Natl Acad Sci U S A (2009) 0.92
Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti-inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia. Brain Behav (2012) 0.90
Central nervous system mast cells in peripheral inflammatory nociception. Mol Pain (2011) 0.86
Growth factors in synaptic function. Front Synaptic Neurosci (2013) 0.85
Peripheral nerve injury sensitizes neonatal dorsal horn neurons to tumor necrosis factor-alpha. Mol Pain (2009) 0.85
Spinal astrogliosis in pain models: cause and effects. Cell Mol Neurobiol (2009) 0.85
MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice. Neuroscience (2009) 0.85
Intra-neural administration of fractalkine attenuates neuropathic pain-related behaviour. J Neurochem (2008) 0.84
Tumor necrosis factor activation of vagal afferent terminal calcium is blocked by cannabinoids. J Neurosci (2012) 0.79
Activation of different signals identified with glia cells contribute to the progression of hyperalgesia. Cell Mol Neurobiol (2012) 0.79
TNF-α Differentially Regulates Synaptic Plasticity in the Hippocampus and Spinal Cord by Microglia-Dependent Mechanisms after Peripheral Nerve Injury. J Neurosci (2017) 0.78
Interleukin-1β overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents. Mol Pain (2016) 0.78
Involvement of CX3CL1/CX3CR1 signaling in spinal long term potentiation. PLoS One (2015) 0.78
Long-term potentiation can be induced in the CA1 region of hippocampus in the absence of αCaMKII T286-autophosphorylation. Learn Mem (2014) 0.77
Glial TLR4 signaling does not contribute to opioid-induced depression of respiration. J Appl Physiol (1985) (2014) 0.76
Altered neuronatin expression in the rat dorsal root ganglion after sciatic nerve transection. J Biomed Sci (2010) 0.76
Nonopioid (Dexmedetomidine, Dexamethasone, Magnesium) Adjuvant to Ropivacaine Caudal Anesthesia in Pediatric Patients Undergoing Infraumbilical Surgeries: A Comparative Study. Anesth Essays Res (2017) 0.75
Src-family kinases activation in spinal microglia contributes to central sensitization and chronic pain after lumbar disc herniation. Mol Pain (2017) 0.75
Erlotinib in lung cancer - molecular and clinical predictors of outcome. N Engl J Med (2005) 13.01
Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol (2002) 10.95
Poly(ADP-ribosyl)ation by PARP-1: 'PAR-laying' NAD+ into a nuclear signal. Genes Dev (2005) 4.61
Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol (2008) 3.97
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest (2006) 3.72
Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. J Clin Invest (2006) 3.33
Ca2+/Calmodulin-dependent protein kinase II phosphorylation of ryanodine receptor does affect calcium sparks in mouse ventricular myocytes. Circ Res (2006) 3.26
Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II. J Clin Invest (2003) 3.15
Transgenic CaMKIIdeltaC overexpression uniquely alters cardiac myocyte Ca2+ handling: reduced SR Ca2+ load and activated SR Ca2+ release. Circ Res (2003) 3.04
Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest (2009) 2.98
Increased sarcoplasmic reticulum calcium leak but unaltered contractility by acute CaMKII overexpression in isolated rabbit cardiac myocytes. Circ Res (2005) 2.50
Genomic analyses of transcription factor binding, histone acetylation, and gene expression reveal mechanistically distinct classes of estrogen-regulated promoters. Mol Cell Biol (2007) 2.33
Stat3 regulates microtubules by antagonizing the depolymerization activity of stathmin. J Cell Biol (2006) 2.21
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. J Clin Invest (2008) 2.19
Interface-induced superconductivity and strain-dependent spin density waves in FeSe/SrTiO3 thin films. Nat Mater (2013) 2.15
A computational framework for influenza antigenic cartography. PLoS Comput Biol (2010) 2.14
GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction. EMBO J (2003) 2.00
Widespread production of extracellular superoxide by heterotrophic bacteria. Science (2013) 1.84
The DNA binding and catalytic domains of poly(ADP-ribose) polymerase 1 cooperate in the regulation of chromatin structure and transcription. Mol Cell Biol (2007) 1.82
CD4+ CD25+ Treg cells inhibit human memory gammadelta T cells to produce IFN-gamma in response to M tuberculosis antigen ESAT-6. Blood (2008) 1.81
TNF-α contributes to up-regulation of Nav1.3 and Nav1.8 in DRG neurons following motor fiber injury. Pain (2010) 1.79
Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses. J Immunol (2005) 1.75
Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol (2007) 1.70
Cancer genomics: technology, discovery, and translation. J Clin Oncol (2012) 1.70
Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase. Curr Biol (2002) 1.69
Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy. Mol Pain (2011) 1.66
Antibiotic resistance genes in water environment. Appl Microbiol Biotechnol (2009) 1.63
Upregulation of GLUT1 expression is necessary for hypertrophy and survival of neonatal rat cardiomyocytes. J Mol Cell Cardiol (2003) 1.62
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. J Neurosci (2009) 1.62
Cardiac hypertrophy and heart failure development through Gq and CaM kinase II signaling. J Cardiovasc Pharmacol (2010) 1.61
Intrabiliary RF heat-enhanced local chemotherapy of a cholangiocarcinoma cell line: monitoring with dual-modality imaging--preclinical study. Radiology (2013) 1.56
Validation of KRAS testing for anti-EGFR therapeutic decisions for patients with metastatic colorectal carcinoma. Arch Pathol Lab Med (2012) 1.56
The role of tumor necrosis factor-alpha in the neuropathic pain induced by Lumbar 5 ventral root transection in rat. Pain (2006) 1.49
Feasibility of real time next generation sequencing of cancer genes linked to drug response: results from a clinical trial. Int J Cancer (2012) 1.49
The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methylation-dependent mechanism and acts as a translational repressor. Exp Cell Res (2007) 1.47
Interaction of radiolabeled antibodies with fungal cells and components of the immune system in vitro and during radioimmunotherapy for experimental fungal infection. J Infect Dis (2006) 1.47
Management options for reducing the release of antibiotics and antibiotic resistance genes to the environment. Environ Health Perspect (2013) 1.42
Peripheral nerve injury leads to working memory deficits and dysfunction of the hippocampus by upregulation of TNF-α in rodents. Neuropsychopharmacology (2011) 1.38
An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase. J Biol Chem (2002) 1.37
Acquisition of adult-like TLR4 and TLR9 responses during the first year of life. PLoS One (2010) 1.37
Landau quantization of topological surface states in Bi2Se3. Phys Rev Lett (2010) 1.36
Direct observation of nodes and twofold symmetry in FeSe superconductor. Science (2011) 1.35
A novel sequence in the coiled-coil domain of Stat3 essential for its nuclear translocation. J Biol Chem (2003) 1.32
Immunotherapy with chimeric NKG2D receptors leads to long-term tumor-free survival and development of host antitumor immunity in murine ovarian cancer. J Immunol (2008) 1.32
Global analysis of transcriptional regulation by poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in MCF-7 human breast cancer cells. J Biol Chem (2009) 1.32
CO(2)-driven ocean acidification alters and weakens integrity of the calcareous tubes produced by the serpulid tubeworm, Hydroides elegans. PLoS One (2012) 1.31
Self-assembly of large-scale and ultrathin silver nanoplate films with tunable plasmon resonance properties. ACS Nano (2011) 1.30
Bacterial communities in different sections of a municipal wastewater treatment plant revealed by 16S rDNA 454 pyrosequencing. Appl Microbiol Biotechnol (2012) 1.30
Biases during DNA extraction of activated sludge samples revealed by high throughput sequencing. Appl Microbiol Biotechnol (2012) 1.28
Plasma IP-10 is associated with rapid disease progression in early HIV-1 infection. Viral Immunol (2012) 1.28
Biased diversity metrics revealed by bacterial 16S pyrotags derived from different primer sets. PLoS One (2013) 1.27
Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury. Proteomics (2009) 1.27
Metagenomic and metatranscriptomic analysis of microbial community structure and gene expression of activated sludge. PLoS One (2012) 1.24
Dendritic cells are responsible for the capacity of CpG oligodeoxynucleotides to act as an adjuvant for protective vaccine immunity against Leishmania major in mice. J Exp Med (2003) 1.24
Role of spinal cord alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in complete Freund's adjuvant-induced inflammatory pain. Mol Pain (2008) 1.24
Mechanisms regulating mercury bioavailability for methylating microorganisms in the aquatic environment: a critical review. Environ Sci Technol (2013) 1.23
Bioproducts from Aureobasidium pullulans, a biotechnologically important yeast. Appl Microbiol Biotechnol (2009) 1.22
Activation of phosphatidylinositol 3-kinase and protein kinase B/Akt in dorsal root ganglia and spinal cord contributes to the neuropathic pain induced by spinal nerve ligation in rats. Exp Neurol (2007) 1.21
Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs. Nucleic Acids Res (2009) 1.21
Analysis of the bacterial community in a laboratory-scale nitrification reactor and a wastewater treatment plant by 454-pyrosequencing. Water Res (2011) 1.21
IL-2 receptor blockade inhibits late, but not early, IFN-gamma and CD40 ligand expression in human T cells: disruption of both IL-12-dependent and -independent pathways of IFN-gamma production. J Immunol (2002) 1.20
Concepts and applications for influenza antigenic cartography. Influenza Other Respir Viruses (2011) 1.19
DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression. BMC Mol Biol (2010) 1.19
Alzheimer's disease amyloid beta-protein and synaptic function. Neuromolecular Med (2009) 1.19
Ursolic acid-induced AMP-activated protein kinase (AMPK) activation contributes to growth inhibition and apoptosis in human bladder cancer T24 cells. Biochem Biophys Res Commun (2012) 1.17
Chimeric NKG2D receptor-bearing T cells as immunotherapy for ovarian cancer. Cancer Res (2007) 1.16
Evaluating total lymphocyte count as a surrogate marker for CD4 cell count in the management of HIV-infected patients in resource-limited settings: a study from China. PLoS One (2013) 1.15
Suppression of terpenoid synthesis in plants by a virus promotes its mutualism with vectors. Ecol Lett (2012) 1.14
Signaling by higher inositol polyphosphates. Synthesis of bisdiphosphoinositol tetrakisphosphate ("InsP8") is selectively activated by hyperosmotic stress. J Biol Chem (2004) 1.13
The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck. Head Neck Oncol (2011) 1.13
Integrative analysis of many weighted co-expression networks using tensor computation. PLoS Comput Biol (2011) 1.12
Gold nanoparticle thin films fabricated by electrophoretic deposition method for highly sensitive SERS application. Nanoscale Res Lett (2012) 1.12
Opioid receptor-triggered spinal mTORC1 activation contributes to morphine tolerance and hyperalgesia. J Clin Invest (2014) 1.11
Using sequence data to infer the antigenicity of influenza virus. MBio (2013) 1.10
Optimization of fixation methods for observation of bacterial cell morphology and surface ultrastructures by atomic force microscopy. Appl Microbiol Biotechnol (2011) 1.10
Effects of lovastatin on Rho isoform expression, activity, and association with guanine nucleotide dissociation inhibitors. Biochem Pharmacol (2007) 1.09
Molecular characterization of the effects of Y-27632. Cell Motil Cytoskeleton (2007) 1.09
IFN-gamma mediates the death of Th1 cells in a paracrine manner. J Immunol (2008) 1.09
p38 activation in uninjured primary afferent neurons and in spinal microglia contributes to the development of neuropathic pain induced by selective motor fiber injury. Exp Neurol (2006) 1.09
Roles of CaMKII, PKA, and PKC in the induction and maintenance of LTP of C-fiber-evoked field potentials in rat spinal dorsal horn. J Neurophysiol (2003) 1.08
Inulinase-expressing microorganisms and applications of inulinases. Appl Microbiol Biotechnol (2009) 1.07
Pathogenic bacteria in sewage treatment plants as revealed by 454 pyrosequencing. Environ Sci Technol (2011) 1.07
Protein kinase C delta associates with the interleukin-6 receptor subunit glycoprotein (gp) 130 via Stat3 and enhances Stat3-gp130 interaction. J Biol Chem (2002) 1.07
Probing superexchange interaction in molecular magnets by spin-flip spectroscopy and microscopy. Phys Rev Lett (2008) 1.07
Branch-like hierarchical heterostructure (α-Fe2O3/TiO2): a novel sensing material for trimethylamine gas sensor. ACS Appl Mater Interfaces (2013) 1.06
Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletion. J Biol Chem (2003) 1.05
Enormous goiter in posterior mediastinum: report of 2 cases and literature review. J Formos Med Assoc (2009) 1.05
Transcriptional silencing of the death gene BNIP3 by cooperative action of NF-kappaB and histone deacetylase 1 in ventricular myocytes. Circ Res (2006) 1.05
Precise determination of time to reach viral load set point after acute HIV-1 infection. J Acquir Immune Defic Syndr (2012) 1.05
Occurrence, abundance, and diversity of tetracycline resistance genes in 15 sewage treatment plants across China and other global locations. Environ Sci Technol (2011) 1.05