PubRank

Kazutoshi Mori

Author PubWeight™ 106.84‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol 2006 6.45
2 IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 2002 6.37
3 Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. Dev Cell 2007 5.45
4 A time-dependent phase shift in the mammalian unfolded protein response. Dev Cell 2003 4.99
5 XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum. J Cell Biol 2004 4.03
6 Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response. Biochem J 2002 3.36
7 XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. Cancer Res 2004 3.24
8 Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. J Cell Biol 2006 2.76
9 Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha. J Biol Chem 2005 2.71
10 pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response. J Cell Biol 2006 2.62
11 Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II. J Biochem 2004 2.62
12 ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum. Cell Struct Funct 2008 2.42
13 Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway. J Virol 2002 2.39
14 Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response. J Biol Chem 2004 2.29
15 Activation of the ATF6, XBP1 and grp78 genes in human hepatocellular carcinoma: a possible involvement of the ER stress pathway in hepatocarcinogenesis. J Hepatol 2003 2.28
16 Sustained activation of XBP1 splicing leads to endothelial apoptosis and atherosclerosis development in response to disturbed flow. Proc Natl Acad Sci U S A 2009 1.74
17 Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress. Mol Biol Cell 2010 1.70
18 The anti-apoptotic role of the unfolded protein response in Bcr-Abl-positive leukemia cells. Leuk Res 2009 1.69
19 Nitric oxide-induced apoptosis in RAW 264.7 macrophages is mediated by endoplasmic reticulum stress pathway involving ATF6 and CHOP. J Biol Chem 2002 1.68
20 Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress. Mol Cell Biol 2006 1.60
21 Vascular endothelial cell growth-activated XBP1 splicing in endothelial cells is crucial for angiogenesis. Circulation 2013 1.60
22 A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6. J Biol Chem 2003 1.57
23 Deletion of Atf6α impairs astroglial activation and enhances neuronal death following brain ischemia in mice. J Neurochem 2015 1.48
24 Galpha(12) and Galpha(13) interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity. Curr Biol 2002 1.47
25 Reduction of disulfide bridges in the lumenal domain of ATF6 in response to glucose starvation. Cell Struct Funct 2006 1.47
26 A thrombospondin-dependent pathway for a protective ER stress response. Cell 2012 1.45
27 Unconventional splicing of XBP1 mRNA occurs in the cytoplasm during the mammalian unfolded protein response. J Cell Sci 2009 1.39
28 ATF6 modulates SREBP2-mediated lipogenesis. EMBO J 2004 1.36
29 The endoplasmic reticulum stress response is stimulated through the continuous activation of transcription factors ATF6 and XBP1 in Ins2+/Akita pancreatic beta cells. Genes Cells 2004 1.32
30 Activation of mammalian unfolded protein response is compatible with the quality control system operating in the endoplasmic reticulum. Mol Biol Cell 2004 1.29
31 Dysfunction of the unfolded protein response during global brain ischemia and reperfusion. J Cereb Blood Flow Metab 2003 1.21
32 Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers. Mol Cell Biol 2002 1.17
33 A role for the unfolded protein response in optimizing antibody secretion. Mol Immunol 2004 1.10
34 The fusion oncoprotein PML-RARalpha induces endoplasmic reticulum (ER)-associated degradation of N-CoR and ER stress. J Biol Chem 2003 1.10
35 The endoplasmic reticulum stress sensor, ATF6α, protects against neurotoxin-induced dopaminergic neuronal death. J Biol Chem 2010 1.09
36 pXBP1(U), a negative regulator of the unfolded protein response activator pXBP1(S), targets ATF6 but not ATF4 in proteasome-mediated degradation. Cell Struct Funct 2009 1.08
37 Rapostlin is a novel effector of Rnd2 GTPase inducing neurite branching. J Biol Chem 2002 1.06
38 Human HRD1 promoter carries a functional unfolded protein response element to which XBP1 but not ATF6 directly binds. J Biochem 2008 1.04
39 Atf6α-null mice are glucose intolerant due to pancreatic β-cell failure on a high-fat diet but partially resistant to diet-induced insulin resistance. Metabolism 2012 1.03
40 The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavage. J Biol Chem 2009 0.99
41 Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation. J Biol Chem 2007 0.98
42 p31 deficiency influences endoplasmic reticulum tubular morphology and cell survival. Mol Cell Biol 2009 0.98
43 An IFN-γ-stimulated ATF6-C/EBP-β-signaling pathway critical for the expression of Death Associated Protein Kinase 1 and induction of autophagy. Proc Natl Acad Sci U S A 2012 0.97
44 Deficiency of ATP2C1, a Golgi ion pump, induces secretory pathway defects in endoplasmic reticulum (ER)-associated degradation and sensitivity to ER stress. J Biol Chem 2004 0.96
45 Luminal domain of ATF6 alone is sufficient for sensing endoplasmic reticulum stress and subsequent transport to the Golgi apparatus. Cell Struct Funct 2010 0.95
46 Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress. Mol Cell Biol 2005 0.93
47 Autoregulation of the HAC1 gene is required for sustained activation of the yeast unfolded protein response. Genes Cells 2004 0.92
48 Endoplasmic reticulum stress increases the expression and function of toll-like receptor-2 in epithelial cells. Biochem Biophys Res Commun 2010 0.91
49 Transformation-associated gene regulation by ATF6alpha during hepatocarcinogenesis. FEBS Lett 2005 0.90
50 The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein. J Biol Chem 2013 0.89
51 XBP1 is critical to protect cells from endoplasmic reticulum stress: evidence from Site-2 protease-deficient Chinese hamster ovary cells. Cell Struct Funct 2006 0.89
52 ATF6alpha promotes astroglial activation and neuronal survival in a chronic mouse model of Parkinson's disease. PLoS One 2012 0.87
53 ATF6α/β-mediated adjustment of ER chaperone levels is essential for development of the notochord in medaka fish. Mol Biol Cell 2013 0.87
54 The specialized unfolded protein response of B lymphocytes: ATF6α-independent development of antibody-secreting B cells. Mol Immunol 2012 0.87
55 SEL1L is required for endoplasmic reticulum-associated degradation of misfolded luminal proteins but not transmembrane proteins in chicken DT40 cell line. Cell Struct Funct 2011 0.86
56 The cargo receptor ERGIC-53 is a target of the unfolded protein response. Biochem Biophys Res Commun 2003 0.84
57 Vps4-A (vacuolar protein sorting 4-A) is a binding partner for a novel Rho family GTPase, Rnd2. Biochem J 2002 0.84
58 A cellular UDP-glucose deficiency causes overexpression of glucose/oxygen-regulated proteins independent of the endoplasmic reticulum stress elements. J Biol Chem 2004 0.83
59 The antipsychotic olanzapine induces apoptosis in insulin-secreting pancreatic β cells by blocking PERK-mediated translational attenuation. Cell Struct Funct 2013 0.83
60 Vertebrate unfolded protein response: mammalian signaling pathways are conserved in Medaka fish. Cell Struct Funct 2011 0.81
61 Developmental changes in expression of small GTPase RhoG mRNA in the rat brain. Brain Res Mol Brain Res 2002 0.78
62 Activating transcription factor 6α is required for the vasopressin neuron system to maintain water balance under dehydration in male mice. Endocrinology 2014 0.77
63 Analysis of ATF6 activation in Site-2 protease-deficient Chinese hamster ovary cells. Cell Struct Funct 2006 0.77
64 Activation of the Unfolded Protein Response in Sporadic Inclusion-Body Myositis but Not in Hereditary GNE Inclusion-Body Myopathy. J Neuropathol Exp Neurol 2015 0.76
65 Correction: A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models. PLoS One 2016 0.75
66 Lasker Award winner Kazutoshi Mori. Nat Med 2014 0.75
67 [Mannose trimming mechanism in endoplasmic reticulum-associated degradation of glycoproteins]. Seikagaku 2016 0.75