Published in J Membr Biol on November 07, 2006
Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway. J Cell Biol (2008) 2.08
Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens. J Cell Biol (2009) 1.30
Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line. J Biol Chem (2008) 1.25
Localization and structure of the ankyrin-binding site on beta2-spectrin. J Biol Chem (2008) 1.21
The assembly and maintenance of epithelial junctions in C. elegans. Front Biosci (Landmark Ed) (2009) 1.01
The yeast Wsc1 cell surface sensor behaves like a nanospring in vivo. Nat Chem Biol (2009) 1.01
Cell organization, growth, and neural and cardiac development require αII-spectrin. J Cell Sci (2011) 0.99
Compartmentation of membrane processes and nucleotide dynamics in diffusion-restricted cardiac cell microenvironment. J Mol Cell Cardiol (2011) 0.93
Unexpected complexity in the mechanisms that target assembly of the spectrin cytoskeleton. J Biol Chem (2008) 0.87
Tropomodulin 1 constrains fiber cell geometry during elongation and maturation in the lens cortex. J Histochem Cytochem (2012) 0.83
Characterization and expression of a heart-selective alternatively spliced variant of alpha II-spectrin, cardi+, during development in the rat. J Mol Cell Cardiol (2010) 0.81
Transgene rescue identifies an essential function for Drosophila beta spectrin in the nervous system and a selective requirement for ankyrin-2-binding activity. Mol Biol Cell (2010) 0.79
Erythrocyte stiffness during morphological remodeling induced by carbon ion radiation. PLoS One (2014) 0.78
Genetic studies of spectrin in the larval fat body of Drosophila melanogaster: evidence for a novel lipid uptake apparatus. Genetics (2013) 0.77
The Drosophila Anion Exchanger (DAE) lacks a detectable interaction with the spectrin cytoskeleton. J Negat Results Biomed (2010) 0.77
ERM proteins and merlin: integrators at the cell cortex. Nat Rev Mol Cell Biol (2002) 8.41
Origins of cell polarity. Cell (1996) 7.99
Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues. Physiol Rev (2001) 6.31
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death. Nature (2003) 5.94
AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing. J Cell Biol (1998) 4.41
A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon. J Neurosci (2006) 4.10
AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier. J Biol Chem (1995) 4.03
Novel function of the cell adhesion molecule uvomorulin as an inducer of cell surface polarity. Cell (1990) 3.75
Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions. Annu Rev Biochem (2005) 3.74
Fodrin: axonally transported polypeptides associated with the internal periphery of many cells. J Cell Biol (1981) 3.65
Lateral mobility of band 3 in the human erythrocyte membrane studied by fluorescence photobleaching recovery: evidence for control by cytoskeletal interactions. Proc Natl Acad Sci U S A (1980) 3.62
Ankyrin binding to (Na+ + K+)ATPase and implications for the organization of membrane domains in polarized cells. Nature (1987) 3.46
Visualization of the protein associations in the erythrocyte membrane skeleton. Proc Natl Acad Sci U S A (1985) 3.26
Dynamics of membrane-skeleton (fodrin) organization during development of polarity in Madin-Darby canine kidney epithelial cells. J Cell Biol (1986) 3.24
A targeting motif involved in sodium channel clustering at the axonal initial segment. Science (2003) 3.02
An F-actin- and calmodulin-binding protein from isolated intestinal brush borders has a morphology related to spectrin. Cell (1982) 2.89
Nav1.5 E1053K mutation causing Brugada syndrome blocks binding to ankyrin-G and expression of Nav1.5 on the surface of cardiomyocytes. Proc Natl Acad Sci U S A (2004) 2.88
Erythrocyte spectrin is comprised of many homologous triple helical segments. Nature (1984) 2.78
Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin. Nature (1982) 2.74
Crystal structure of the repetitive segments of spectrin. Science (1993) 2.61
Ankyrin and spectrin associate with voltage-dependent sodium channels in brain. Nature (1988) 2.60
The spectrin-actin junction of erythrocyte membrane skeletons. Biochim Biophys Acta (1989) 2.50
Spectrin mutations cause spinocerebellar ataxia type 5. Nat Genet (2006) 2.34
A membrane-cytoskeletal complex containing Na+,K+-ATPase, ankyrin, and fodrin in Madin-Darby canine kidney (MDCK) cells: implications for the biogenesis of epithelial cell polarity. J Cell Biol (1989) 2.28
Identification of a conserved ankyrin-binding motif in the family of sodium channel alpha subunits. J Biol Chem (2003) 2.22
Spectrin tethers and mesh in the biosynthetic pathway. J Cell Sci (2000) 2.21
Modulation of fodrin (membrane skeleton) stability by cell-cell contact in Madin-Darby canine kidney epithelial cells. J Cell Biol (1987) 2.20
Lateral mobility of human erythrocyte integral membrane proteins. Nature (1977) 2.19
Tyrosine phosphorylation at a site highly conserved in the L1 family of cell adhesion molecules abolishes ankyrin binding and increases lateral mobility of neurofascin. J Cell Biol (1997) 2.19
[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier. J Cell Biol (2002) 2.15
betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system. J Cell Biol (2000) 2.15
An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane. EMBO J (1994) 2.10
Primary structure of the brain alpha-spectrin. J Cell Biol (1989) 2.08
Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain. PLoS Biol (2005) 2.06
Red blood cell membrane disorders. Br J Haematol (1999) 1.97
Ankyrin-binding proteins related to nervous system cell adhesion molecules: candidates to provide transmembrane and intercellular connections in adult brain. J Cell Biol (1993) 1.96
Brain ankyrin. A membrane-associated protein with binding sites for spectrin, tubulin, and the cytoplasmic domain of the erythrocyte anion channel. J Biol Chem (1984) 1.95
Mouse T lymphoma cells contain a transmembrane glycoprotein (GP85) that binds ankyrin. J Cell Biol (1988) 1.89
Colocalization of band 3 with ankyrin and spectrin at the basal membrane of intercalated cells in the rat kidney. Science (1985) 1.87
Ankyrin binds to the 15th repetitive unit of erythroid and nonerythroid beta-spectrin. J Cell Biol (1991) 1.85
Polarized axonal surface expression of neuronal KCNQ channels is mediated by multiple signals in the KCNQ2 and KCNQ3 C-terminal domains. Proc Natl Acad Sci U S A (2006) 1.84
Gamma actin, spectrin, and intermediate filament proteins colocalize with vinculin at costameres, myofibril-to-sarcolemma attachment sites. Cell Motil (1983) 1.71
BetaIV spectrins are essential for membrane stability and the molecular organization of nodes of Ranvier. J Neurosci (2004) 1.69
Anchorage of a band 3 population at the erythrocyte cytoplasmic membrane surface: protein rotational diffusion measurements. Proc Natl Acad Sci U S A (1980) 1.62
Mutant beta-spectrin 4 causes auditory and motor neuropathies in quivering mice. Nat Genet (2001) 1.60
Cell shape and interaction defects in alpha-spectrin mutants of Drosophila melanogaster. J Cell Biol (1993) 1.58
Molecular characterization and expression of the (Na+ + K+)-ATPase alpha-subunit in Drosophila melanogaster. EMBO J (1989) 1.54
A widely expressed betaIII spectrin associated with Golgi and cytoplasmic vesicles. Proc Natl Acad Sci U S A (1998) 1.53
Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins. Nature (2001) 1.53
Ankyrins and cellular targeting of diverse membrane proteins to physiological sites. Curr Opin Cell Biol (2001) 1.53
Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes. J Biol Chem (2004) 1.52
Lateral membrane biogenesis in human bronchial epithelial cells requires 190-kDa ankyrin-G. J Biol Chem (2004) 1.44
Ankyrin-B is required for intracellular sorting of structurally diverse Ca2+ homeostasis proteins. J Cell Biol (1999) 1.44
Nervous system defects of AnkyrinB (-/-) mice suggest functional overlap between the cell adhesion molecule L1 and 440-kD AnkyrinB in premyelinated axons. J Cell Biol (1998) 1.43
Point mutation in the beta-spectrin gene associated with alpha I/74 hereditary elliptocytosis. Implications for the mechanism of spectrin dimer self-association. J Clin Invest (1990) 1.41
sma-1 encodes a betaH-spectrin homolog required for Caenorhabditis elegans morphogenesis. Development (1998) 1.41
Neuroglian-mediated cell adhesion induces assembly of the membrane skeleton at cell contact sites. J Cell Biol (1996) 1.38
Ank3 (epithelial ankyrin), a widely distributed new member of the ankyrin gene family and the major ankyrin in kidney, is expressed in alternatively spliced forms, including forms that lack the repeat domain. J Cell Biol (1995) 1.37
BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments. J Cell Biol (2004) 1.36
The cardiac Na+-Ca2+ exchanger binds to the cytoskeletal protein ankyrin. J Biol Chem (1993) 1.34
Ankyrin binds to two distinct cytoplasmic domains of Na,K-ATPase alpha subunit. Proc Natl Acad Sci U S A (1994) 1.33
Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice. J Cell Biol (1991) 1.32
Brain spectrin binding to the NMDA receptor is regulated by phosphorylation, calcium and calmodulin. EMBO J (1998) 1.31
The involvement of ankyrin in the regulation of inositol 1,4,5-trisphosphate receptor-mediated internal Ca2+ release from Ca2+ storage vesicles in mouse T-lymphoma cells. J Biol Chem (1993) 1.30
Structural comparisons of calponin homology domains: implications for actin binding. Structure (1998) 1.30
Drosophila beta spectrin functions independently of alpha spectrin to polarize the Na,K ATPase in epithelial cells. J Cell Biol (2000) 1.28
Brush border spectrin is required for early endosome recycling in Drosophila. J Cell Sci (2006) 1.28
The cGMP-gated cation channel of bovine rod photoreceptor cells is associated with a 240-kDa protein exhibiting immunochemical cross-reactivity with spectrin. J Biol Chem (1990) 1.27
Trafficking and cell surface stability of the epithelial Na+ channel expressed in epithelial Madin-Darby canine kidney cells. J Biol Chem (2001) 1.26
Rh-RhAG/ankyrin-R, a new interaction site between the membrane bilayer and the red cell skeleton, is impaired by Rh(null)-associated mutation. J Biol Chem (2003) 1.24
Structure of the ankyrin-binding domain of alpha-Na,K-ATPase. J Biol Chem (1998) 1.15
Erythrocyte and brain forms of spectrin in cerebellum: distinct membrane-cytoskeletal domains in neurons. Science (1983) 1.15
A beta-spectrin isoform from Drosophila (beta H) is similar in size to vertebrate dystrophin. J Cell Biol (1990) 1.10
The spectrin-ankyrin skeleton controls CD45 surface display and interleukin-2 production. Immunity (2002) 1.08
Membrane-cytoskeleton dynamics in rat parietal cells: mobilization of actin and spectrin upon stimulation of gastric acid secretion. J Cell Biol (1989) 1.08
Mammalian alpha I-spectrin is a neofunctionalized polypeptide adapted to small highly deformable erythrocytes. Proc Natl Acad Sci U S A (2006) 1.06
A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix. J Biol Chem (2001) 1.06
Ankyrin and beta-spectrin accumulate independently of alpha-spectrin in Drosophila. Proc Natl Acad Sci U S A (1994) 1.05
Ankyrin-based cardiac arrhythmias: a new class of channelopathies due to loss of cellular targeting. Curr Opin Cardiol (2005) 1.04
Role of terminal nonhomologous domains in initiation of human red cell spectrin dimerization. Biochemistry (2001) 0.98
Identification and characterization of beta V spectrin, a mammalian ortholog of Drosophila beta H spectrin. J Biol Chem (2000) 0.95
Spectrin functions upstream of ankyrin in a spectrin cytoskeleton assembly pathway. J Cell Biol (2006) 0.93
Fragmentation of the Golgi apparatus. A role for beta III spectrin and synthesis of phosphatidylinositol 4,5-bisphosphate. J Biol Chem (2002) 0.93
The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells. J Biol Chem (2004) 0.90
A conserved role for L1 as a transmembrane link between neuronal adhesion and membrane cytoskeleton assembly. Cell Adhes Commun (1998) 0.89
Antibodies to betaISigma2 spectrin identify in-homogeneities in the erythrocyte membrane skeleton. Blood Cells Mol Dis (2004) 0.77