Published in Annu Rev Biochem on January 01, 2005
Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim Biophys Acta (2007) 4.74
Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. Nature (2007) 4.59
Scaffold proteins: hubs for controlling the flow of cellular information. Science (2011) 4.00
Oncogenic activation of NF-kappaB. Cold Spring Harb Perspect Biol (2010) 3.30
A specificity map for the PDZ domain family. PLoS Biol (2008) 3.16
The ß subunit of voltage-gated Ca2+ channels. Physiol Rev (2010) 2.30
Scaffolds: interaction platforms for cellular signalling circuits. Trends Cell Biol (2009) 2.15
ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton. Mol Biol Cell (2009) 2.10
Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1. Cold Spring Harb Perspect Biol (2010) 1.95
Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95. J Cell Biol (2009) 1.91
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds. Science (2008) 1.86
E-cadherin homophilic ligation inhibits cell growth and epidermal growth factor receptor signaling independently of other cell interactions. Mol Biol Cell (2007) 1.84
Compartmentalization of the exocyst complex in lipid rafts controls Glut4 vesicle tethering. Mol Biol Cell (2006) 1.75
Deletion of CASK in mice is lethal and impairs synaptic function. Proc Natl Acad Sci U S A (2007) 1.74
Differential trafficking of AMPA and NMDA receptors by SAP102 and PSD-95 underlies synapse development. Proc Natl Acad Sci U S A (2008) 1.68
Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cells. Mol Biol Cell (2006) 1.59
PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nat Neurosci (2012) 1.58
The postsynaptic organization of synapses. Cold Spring Harb Perspect Biol (2011) 1.53
Cytoskeleton out of the cupboard: colon cancer and cytoskeletal changes induced by loss of APC. Nat Rev Cancer (2006) 1.53
Discs large 5 is required for polarization of citron kinase in mitotic neural precursors. Cell Cycle (2010) 1.51
MAGUKs, synaptic development, and synaptic plasticity. Neuroscientist (2011) 1.50
PSD-95 promotes synaptogenesis and multiinnervated spine formation through nitric oxide signaling. J Cell Biol (2008) 1.43
The unique-5 and -6 motifs of ZO-1 regulate tight junction strand localization and scaffolding properties. Mol Biol Cell (2006) 1.40
Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter. Proc Natl Acad Sci U S A (2006) 1.36
Organization of multiprotein complexes at cell-cell junctions. Histochem Cell Biol (2008) 1.33
PSD-95 is required to sustain the molecular organization of the postsynaptic density. J Neurosci (2011) 1.33
Drosophila Varicose, a member of a new subgroup of basolateral MAGUKs, is required for septate junctions and tracheal morphogenesis. Development (2007) 1.33
PAR-1 kinase phosphorylates Dlg and regulates its postsynaptic targeting at the Drosophila neuromuscular junction. Neuron (2007) 1.31
The role of SAP97 in synaptic glutamate receptor dynamics. Proc Natl Acad Sci U S A (2010) 1.30
Local palmitoylation cycles define activity-regulated postsynaptic subdomains. J Cell Biol (2013) 1.26
SAP102 is a highly mobile MAGUK in spines. J Neurosci (2010) 1.22
Basolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cells. Genetics (2008) 1.21
Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules. EMBO J (2011) 1.19
GKAP orchestrates activity-dependent postsynaptic protein remodeling and homeostatic scaling. Nat Neurosci (2012) 1.19
The dual role of zonula occludens (ZO) proteins. J Biomed Biotechnol (2010) 1.19
Organization of beta-adrenoceptor signaling compartments by sympathetic innervation of cardiac myocytes. J Cell Biol (2007) 1.19
JunD represses transcription and translation of the tight junction protein zona occludens-1 modulating intestinal epithelial barrier function. Mol Biol Cell (2008) 1.14
A CaVbeta SH3/guanylate kinase domain interaction regulates multiple properties of voltage-gated Ca2+ channels. J Gen Physiol (2005) 1.14
Molecular evolution of the MAGUK family in metazoan genomes. BMC Evol Biol (2007) 1.14
The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation. Mol Biol Cell (2007) 1.12
Intact retinal pigment epithelium maintained by Nok is essential for retinal epithelial polarity and cellular patterning in zebrafish. J Neurosci (2008) 1.10
Progress in the structural understanding of voltage-gated calcium channel (CaV) function and modulation. Channels (Austin) (2010) 1.10
Synaptic localization and function of Sidekick recognition molecules require MAGI scaffolding proteins. J Neurosci (2010) 1.10
Evolution of the MAGUK protein gene family in premetazoan lineages. BMC Evol Biol (2010) 1.07
Axospinous synaptic subtype-specific differences in structure, size, ionotropic receptor expression, and connectivity in apical dendritic regions of rat hippocampal CA1 pyramidal neurons. J Comp Neurol (2009) 1.06
Regulated RalBP1 binding to RalA and PSD-95 controls AMPA receptor endocytosis and LTD. PLoS Biol (2009) 1.05
DLGH1 is a negative regulator of T-lymphocyte proliferation. Mol Cell Biol (2007) 1.04
Phosphorylation of threonine-19 of PSD-95 by GSK-3β is required for PSD-95 mobilization and long-term depression. J Neurosci (2013) 1.04
MAGI-1 interacts with Slo1 channel proteins and suppresses Slo1 expression on the cell surface. Am J Physiol Cell Physiol (2009) 1.04
The Src homology 3 domain is required for junctional adhesion molecule binding to the third PDZ domain of the scaffolding protein ZO-1. J Biol Chem (2011) 1.03
Ionotropic glutamate receptors IR64a and IR8a form a functional odorant receptor complex in vivo in Drosophila. J Neurosci (2013) 1.03
Epithelial polarity and spindle orientation: intersecting pathways. Philos Trans R Soc Lond B Biol Sci (2013) 1.03
Palmitoylation-dependent CDKL5-PSD-95 interaction regulates synaptic targeting of CDKL5 and dendritic spine development. Proc Natl Acad Sci U S A (2013) 1.03
Mechanism of auxiliary β-subunit-mediated membrane targeting of L-type (Ca(V)1.2) channels. J Physiol (2011) 1.02
Domain swapping within PDZ2 is responsible for dimerization of ZO proteins. J Biol Chem (2007) 1.02
Postsynaptic membrane addition depends on the Discs-Large-interacting t-SNARE Gtaxin. J Neurosci (2007) 1.02
Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function. Nucleic Acids Res (2011) 1.02
The assembly and maintenance of epithelial junctions in C. elegans. Front Biosci (Landmark Ed) (2009) 1.01
The C. elegans zonula occludens ortholog cooperates with the cadherin complex to recruit actin during morphogenesis. Curr Biol (2008) 1.01
Functional links between membrane transport and the spectrin cytoskeleton. J Membr Biol (2006) 1.00
The structural biology of voltage-gated calcium channel function and regulation. Biochem Soc Trans (2006) 0.99
SynCAM1 recruits NMDA receptors via protein 4.1B. Mol Cell Neurosci (2009) 0.99
Viagra for your synapses: Enhancement of hippocampal long-term potentiation by activation of beta-adrenergic receptors. Cell Signal (2009) 0.99
The actin cytoskeleton as a barrier to virus infection of polarized epithelial cells. Viruses (2011) 0.99
Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance. EMBO J (2009) 0.98
Polychaetoid controls patterning by modulating adhesion in the Drosophila pupal retina. Dev Biol (2008) 0.98
In vivo induction of postsynaptic molecular assembly by the cell adhesion molecule Fasciclin2. J Cell Biol (2007) 0.98
Phosphorylation of a PDZ domain extension modulates binding affinity and interdomain interactions in postsynaptic density-95 (PSD-95) protein, a membrane-associated guanylate kinase (MAGUK). J Biol Chem (2011) 0.98
Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway. J Neurosci (2013) 0.97
DLGS97/SAP97 is developmentally upregulated and is required for complex adult behaviors and synapse morphology and function. J Neurosci (2008) 0.97
Structure of Crumbs tail in complex with the PALS1 PDZ-SH3-GK tandem reveals a highly specific assembly mechanism for the apical Crumbs complex. Proc Natl Acad Sci U S A (2014) 0.95
Scaffold protein Disc large homolog 1 is required for T-cell receptor-induced activation of regulatory T-cell function. Proc Natl Acad Sci U S A (2012) 0.95
Protein kinase Cα promotes cell migration through a PDZ-dependent interaction with its novel substrate discs large homolog 1 (DLG1). J Biol Chem (2011) 0.95
Insights into regulated ligand binding sites from the structure of ZO-1 Src homology 3-guanylate kinase module. J Biol Chem (2010) 0.95
CASK interacts with PMCA4b and JAM-A on the mouse sperm flagellum to regulate Ca2+ homeostasis and motility. J Cell Physiol (2012) 0.94
Proteomic and bioinformatic analysis of epithelial tight junction reveals an unexpected cluster of synaptic molecules. Biol Direct (2006) 0.94
EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability. Infect Immun (2008) 0.94
Cyclin-dependent kinase 5 regulates PSD-95 ubiquitination in neurons. J Neurosci (2011) 0.94
New aspects of the molecular constituents of tissue barriers. J Neural Transm (Vienna) (2010) 0.93
Inactivation of tumor suppressor Dlg1 augments transformation of a T-cell line induced by human T-cell leukemia virus type 1 Tax protein. Retrovirology (2006) 0.93
Tight junctions in salivary epithelium. J Biomed Biotechnol (2010) 0.93
Cell adhesion molecule 1: a novel risk factor for venous thrombosis. Blood (2009) 0.92
"You Shall Not Pass"-tight junctions of the blood brain barrier. Front Neurosci (2014) 0.92
How old is my gene? Trends Genet (2013) 0.91
Intramolecular interactions between the SRC homology 3 and guanylate kinase domains of discs large regulate its function in asymmetric cell division. J Biol Chem (2009) 0.91
Molecular interactions of the plasma membrane calcium ATPase 2 at pre- and post-synaptic sites in rat cerebellum. Neuroscience (2009) 0.91
Structure of an enzyme-derived phosphoprotein recognition domain. PLoS One (2012) 0.91
AMPAR trafficking in synapse maturation and plasticity. Cell Mol Life Sci (2013) 0.91
Central regulation of locomotor behavior of Drosophila melanogaster depends on a CASK isoform containing CaMK-like and L27 domains. Genetics (2010) 0.91
Conversion of the enzyme guanylate kinase into a mitotic-spindle orienting protein by a single mutation that inhibits GMP-induced closing. Proc Natl Acad Sci U S A (2011) 0.90
Supertertiary structure of the synaptic MAGuK scaffold proteins is conserved. Proc Natl Acad Sci U S A (2012) 0.90
Receptor-associated proteins and synaptic plasticity. FASEB J (2008) 0.90
Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves. Mol Cell Biol (2011) 0.90
Varicose: a MAGUK required for the maturation and function of Drosophila septate junctions. BMC Dev Biol (2008) 0.89
Organization of central synapses by adhesion molecules. Eur J Neurosci (2010) 0.89
Dlg5 maintains apical aPKC and regulates progenitor differentiation during lung morphogenesis. Dev Biol (2013) 0.88
Polyamines regulate E-cadherin transcription through c-Myc modulating intestinal epithelial barrier function. Am J Physiol Cell Physiol (2009) 0.88
Acute inactivation of PSD-95 destabilizes AMPA receptors at hippocampal synapses. PLoS One (2013) 0.87
Plasma membrane Ca2+-ATPase 4 in murine epididymis: secretion of splice variants in the luminal fluid and a role in sperm maturation. Biol Reprod (2013) 0.87
Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number. Proc Natl Acad Sci U S A (2002) 4.77
Identification of PSD-95 palmitoylating enzymes. Neuron (2004) 4.37
Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins. Neuron (2006) 4.21
Synaptic strength regulated by palmitate cycling on PSD-95. Cell (2002) 4.15
Stargazin modulates AMPA receptor gating and trafficking by distinct domains. Nature (2005) 3.88
Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission. Science (2006) 3.52
Functional studies and distribution define a family of transmembrane AMPA receptor regulatory proteins. J Cell Biol (2003) 3.14
Auxiliary subunits assist AMPA-type glutamate receptors. Science (2006) 3.10
Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression. J Neurosci (2003) 2.53
Protein palmitoylation: a regulator of neuronal development and function. Nat Rev Neurosci (2002) 2.32
Bidirectional synaptic plasticity regulated by phosphorylation of stargazin-like TARPs. Neuron (2005) 2.13
TARP subtypes differentially and dose-dependently control synaptic AMPA receptor gating. Neuron (2007) 2.07
TARP gamma-8 controls hippocampal AMPA receptor number, distribution and synaptic plasticity. Nat Neurosci (2005) 2.04
Dynamic interaction of stargazin-like TARPs with cycling AMPA receptors at synapses. Science (2004) 1.97
Mobile DHHC palmitoylating enzyme mediates activity-sensitive synaptic targeting of PSD-95. J Cell Biol (2009) 1.91
Identification of Golgi-localized acyl transferases that palmitoylate and regulate endothelial nitric oxide synthase. J Cell Biol (2006) 1.79
New transmembrane AMPA receptor regulatory protein isoform, gamma-7, differentially regulates AMPA receptors. J Neurosci (2007) 1.62
Identification and characterization of a major liver lysophosphatidylcholine acyltransferase. J Biol Chem (2008) 1.60
Stargazin is an AMPA receptor auxiliary subunit. Proc Natl Acad Sci U S A (2005) 1.52
Fetal iron deficiency alters the proteome of adult rat hippocampal synaptosomes. Am J Physiol Regul Integr Comp Physiol (2013) 1.50
AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase. J Biol Chem (2008) 1.50
Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins. Neuron (2010) 1.45
Activity-dependent NMDA receptor degradation mediated by retrotranslocation and ubiquitination. Proc Natl Acad Sci U S A (2005) 1.42
Phosphorylation of the postsynaptic density-95 (PSD-95)/discs large/zona occludens-1 binding site of stargazin regulates binding to PSD-95 and synaptic targeting of AMPA receptors. J Neurosci (2002) 1.42
Postsynaptic density-93 clusters Kv1 channels at axon initial segments independently of Caspr2. J Neurosci (2008) 1.41
TARPs differentially decorate AMPA receptors to specify neuropharmacology. Trends Neurosci (2010) 1.39
Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein. J Neurosci (2003) 1.37
AMPA receptor subunit-specific regulation by a distinct family of type II TARPs. Neuron (2008) 1.37
Interaction with the unfolded protein response reveals a role for stargazin in biosynthetic AMPA receptor transport. J Neurosci (2005) 1.35
Molecular constituents of neuronal AMPA receptors. J Cell Biol (2005) 1.31
Effect of knock down of spinal cord PSD-93/chapsin-110 on persistent pain induced by complete Freund's adjuvant and peripheral nerve injury. Pain (2003) 1.29
PSD93 regulates synaptic stability at neuronal cholinergic synapses. J Neurosci (2004) 1.26
Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs. Mol Biol Cell (2004) 1.23
Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms. J Neurosci (2002) 1.22
Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex. J Cell Biol (2005) 1.21
Calcium channel function regulated by the SH3-GK module in beta subunits. Neuron (2004) 1.20
Isolated hypoglossal schwannoma in a 9-year-old child. J Neurosurg Pediatr (2012) 1.20
TARP redundancy is critical for maintaining AMPA receptor function. J Neurosci (2008) 1.18
Interaction of transmembrane AMPA receptor regulatory proteins with multiple membrane associated guanylate kinases. Neuropharmacology (2003) 1.17
nNOS at a glance: implications for brain and brawn. J Cell Sci (2004) 1.17
Stargazin controls the pharmacology of AMPA receptor potentiators. Proc Natl Acad Sci U S A (2006) 1.17
Stargazin interacts functionally with the AMPA receptor glutamate-binding module. Neuropharmacology (2006) 1.13
AMPA receptors and stargazin-like transmembrane AMPA receptor-regulatory proteins mediate hippocampal kainate neurotoxicity. Proc Natl Acad Sci U S A (2007) 1.11
Stargazin differentially controls the trafficking of alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate and kainate receptors. Mol Pharmacol (2003) 1.10
A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65. J Cell Biol (2002) 1.10
Lipid- and protein-mediated multimerization of PSD-95: implications for receptor clustering and assembly of synaptic protein networks. J Cell Sci (2003) 1.09
Cornichon-2 modulates AMPA receptor-transmembrane AMPA receptor regulatory protein assembly to dictate gating and pharmacology. J Neurosci (2011) 1.08
AMPA receptor synaptic targeting regulated by stargazin interactions with the Golgi-resident PDZ protein nPIST. J Neurosci (2004) 1.05
The guanylate kinase domain of the MAGUK PSD-95 binds dynamically to a conserved motif in MAP1a. Nat Struct Mol Biol (2007) 1.01
PDZ binding of TARPγ-8 controls synaptic transmission but not synaptic plasticity. Nat Neurosci (2011) 1.00
Palmitoylation controls trafficking of GAD65 from Golgi membranes to axon-specific endosomes and a Rab5a-dependent pathway to presynaptic clusters. J Cell Sci (2004) 0.99
MALS-3 regulates polarity and early neurogenesis in the developing cerebral cortex. Development (2008) 0.99
Assembly and plasticity of the glutamatergic postsynaptic specialization. Curr Opin Neurobiol (2003) 0.97
Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice. J Cell Biol (2007) 0.97
Organization of postsynaptic density proteins and glutamate receptors in axodendritic and dendrodendritic synapses of the rat olfactory bulb. J Comp Neurol (2003) 0.95
Synaptic transmission regulated by a presynaptic MALS/Liprin-alpha protein complex. Curr Opin Cell Biol (2006) 0.94
Fibroblast growth factor-regulated palmitoylation of the neural cell adhesion molecule determines neuronal morphogenesis. J Neurosci (2008) 0.94
Synaptic glutamate receptor clustering in mice lacking the SH3 and GK domains of SAP97. Eur J Neurosci (2002) 0.93
Functional analysis of the nucleotide binding domain of membrane-associated guanylate kinases. J Biol Chem (2002) 0.92
AMPA receptor modulation by cornichon-2 dictated by transmembrane AMPA receptor regulatory protein isoform. Eur J Neurosci (2011) 0.88
Differential localization of mammalian Lin-7 (MALS/Veli) PDZ proteins in the kidney. Am J Physiol Renal Physiol (2004) 0.87
Acute inactivation of PSD-95 destabilizes AMPA receptors at hippocampal synapses. PLoS One (2013) 0.87
Identification of a monogenic locus (jams1) causing juvenile audiogenic seizures in mice. J Neurosci (2002) 0.87
Early events in glutamate receptor trafficking. Curr Opin Cell Biol (2004) 0.86
Targeted disruption of PSD-93 gene reduces platelet-activating factor-induced neurotoxicity in cultured cortical neurons. Exp Neurol (2004) 0.84
Pharmacological regulation of ion channels by auxiliary subunits. Curr Opin Drug Discov Devel (2007) 0.81
A revised mechanism for the inactivation of bovine liver enoyl-CoA hydratase by (methylenecyclopropyl)formyl-CoA based on unexpected results with the C114A mutant. Biochemistry (2002) 0.80
Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators. J Biol Chem (2011) 0.78
An emerging role for TARPs in neuropsychiatric disorders. Neuropsychopharmacology (2011) 0.76