Published in J Virol on November 08, 2006
Phosphatidylinositol 3-kinase-, actin-, and microtubule-dependent transport of Semliki Forest Virus replication complexes from the plasma membrane to modified lysosomes. J Virol (2010) 1.52
SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication. PLoS Pathog (2011) 1.32
Architecture and biogenesis of plus-strand RNA virus replication factories. World J Virol (2013) 1.30
An amphipathic alpha-helix controls multiple roles of brome mosaic virus protein 1a in RNA replication complex assembly and function. PLoS Pathog (2009) 1.13
Assembly of alphavirus replication complexes from RNA and protein components in a novel trans-replication system in mammalian cells. J Virol (2011) 1.03
Mutations at the palmitoylation site of non-structural protein nsP1 of Semliki Forest virus attenuate virus replication and cause accumulation of compensatory mutations. J Gen Virol (2007) 0.98
Alphavirus RNA synthesis and non-structural protein functions. J Gen Virol (2015) 0.96
Template RNA length determines the size of replication complex spherules for Semliki Forest virus. J Virol (2013) 0.93
Properties of non-structural protein 1 of Semliki Forest virus and its interference with virus replication. J Gen Virol (2008) 0.91
Mitochondrion-enriched anionic phospholipids facilitate flock house virus RNA polymerase membrane association. J Virol (2009) 0.90
In vitro evolution of high-titer, virus-like vesicles containing a single structural protein. Proc Natl Acad Sci U S A (2014) 0.86
Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization. J Virol (2015) 0.86
Molecular defects caused by temperature-sensitive mutations in Semliki Forest virus nsP1. J Virol (2008) 0.84
mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research. J Virol (2015) 0.84
Versatile Trans-Replication Systems for Chikungunya Virus Allow Functional Analysis and Tagging of Every Replicase Protein. PLoS One (2016) 0.83
Heterologous production, purification and characterization of enzymatically active Sindbis virus nonstructural protein nsP1. Protein Expr Purif (2011) 0.83
Hypervariable domain of nonstructural protein nsP3 of Venezuelan equine encephalitis virus determines cell-specific mode of virus replication. J Virol (2013) 0.82
Sequence analysis reveals a conserved extension in the capping enzyme of the alphavirus supergroup, and a homologous domain in nodaviruses. Biol Direct (2015) 0.82
Transfection of infectious RNA and DNA/RNA layered vectors of semliki forest virus by the cell-penetrating peptide based reagent PepFect6. PLoS One (2013) 0.81
RNA Replication and Membrane Modification Require the Same Functions of Alphavirus Nonstructural Proteins. J Virol (2015) 0.81
Recombinant production of the amino terminal cytoplasmic region of dengue virus non-structural protein 4A for structural studies. PLoS One (2014) 0.78
A Novel Mechanism Underlying the Innate Immune Response Induction upon Viral-Dependent Replication of Host Cell mRNA: A Mistake of +sRNA Viruses' Replicases. Front Cell Infect Microbiol (2017) 0.75
Mutational analysis of hepatitis E virus ORF1 "Y-domain": Effects on RNA replication and virion infectivity. World J Gastroenterol (2017) 0.75
Lipid Binding of the Amphipathic Helix Serving as Membrane Anchor of Pestivirus Glycoprotein Erns. PLoS One (2015) 0.75
Chikungunya virus overcomes polyamine depletion by mutation of nsP1 and the opal stop codon to confer enhanced replication and fitness. J Virol (2017) 0.75
Unique and conserved features of genome and proteome of SARS-coronavirus, an early split-off from the coronavirus group 2 lineage. J Mol Biol (2003) 9.09
In vitro mutagenesis of a full-length cDNA clone of Semliki Forest virus: the small 6,000-molecular-weight membrane protein modulates virus release. J Virol (1991) 6.02
Subversion of cellular autophagosomal machinery by RNA viruses. PLoS Biol (2005) 5.84
Global analysis of protein palmitoylation in yeast. Cell (2006) 4.43
Alphavirus RNA replicase is located on the cytoplasmic surface of endosomes and lysosomes. J Cell Biol (1988) 4.27
An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A. J Biol Chem (2001) 3.91
Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA. Cell (1992) 3.89
Viral RNA replication in association with cellular membranes. Curr Top Microbiol Immunol (2005) 3.18
Host range and cytopathogenicity of the highly attenuated MVA strain of vaccinia virus: propagation and generation of recombinant viruses in a nonhuman mammalian cell line. Virology (1997) 3.17
Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus- and plus-strand RNA synthesis. EMBO J (1994) 3.00
Reaction in alphavirus mRNA capping: formation of a covalent complex of nonstructural protein nsP1 with 7-methyl-GMP. Proc Natl Acad Sci U S A (1995) 2.86
Topology of the membrane-associated hepatitis C virus protein NS4B. J Virol (2003) 2.37
ORF1a-encoded replicase subunits are involved in the membrane association of the arterivirus replication complex. J Virol (1998) 2.26
Conservation of the putative methyltransferase domain: a hallmark of the 'Sindbis-like' supergroup of positive-strand RNA viruses. J Gen Virol (1992) 2.24
Biogenesis of the Semliki Forest virus RNA replication complex. J Virol (2001) 2.21
Determinants of membrane association for poliovirus protein 3AB. J Biol Chem (1996) 2.20
The role of the tethering proteins p115 and GM130 in transport through the Golgi apparatus in vivo. Mol Biol Cell (2000) 2.16
Poliovirus 2C protein determinants of membrane binding and rearrangements in mammalian cells. J Virol (1997) 2.13
Semliki Forest virus mRNA capping enzyme requires association with anionic membrane phospholipids for activity. EMBO J (1999) 2.07
Expression of Sindbis virus nsP1 and methyltransferase activity in Escherichia coli. Virology (1991) 1.98
Amino terminal regions of poliovirus 2C protein mediate membrane binding. Virology (1995) 1.79
Amphitropic proteins: regulation by reversible membrane interactions (review). Mol Membr Biol (1999) 1.76
Semliki Forest virus-specific non-structural protein nsP3 is a phosphoprotein. J Gen Virol (1988) 1.71
Interaction of hepatitis C virus proteins with host cell membranes and lipids. Trends Cell Biol (2002) 1.71
Functions of alphavirus nonstructural proteins in RNA replication. Prog Nucleic Acid Res Mol Biol (2002) 1.66
Expression of Semliki Forest virus nsP1-specific methyltransferase in insect cells and in Escherichia coli. J Virol (1994) 1.64
Flock house virus RNA polymerase is a transmembrane protein with amino-terminal sequences sufficient for mitochondrial localization and membrane insertion. J Virol (2002) 1.62
The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment. Structure (2006) 1.60
The alphavirus replicase protein nsP1 is membrane-associated and has affinity to endocytic organelles. Virology (1995) 1.58
The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment. J Virol (2002) 1.56
Properly folded nonstructural polyprotein directs the semliki forest virus replication complex to the endosomal compartment. J Virol (2003) 1.52
Alphavirus nsP3 functions to form replication complexes transcribing negative-strand RNA. J Virol (1994) 1.47
Regulation of Semliki Forest virus RNA replication: a model for the control of alphavirus pathogenesis in invertebrate hosts. Virology (2004) 1.45
The effects of palmitoylation on membrane association of Semliki forest virus RNA capping enzyme. J Biol Chem (1996) 1.44
Studies of a putative amphipathic helix in the N-terminus of poliovirus protein 2C. Virology (1994) 1.43
Isolation and basic characterization of temperature-sensitive mutants from Semliki Forest virus;. Acta Pathol Microbiol Scand B Microbiol Immunol (1974) 1.38
Regulation of the sequential processing of Semliki Forest virus replicase polyprotein. J Biol Chem (2003) 1.34
Determinants for membrane association and permeabilization of the coxsackievirus 2B protein and the identification of the Golgi complex as the target organelle. J Biol Chem (2002) 1.22
A predicted amphipathic helix mediates plasma membrane localization of GRK5. J Biol Chem (2004) 1.19
Effects of palmitoylation of replicase protein nsP1 on alphavirus infection. J Virol (2000) 1.19
Alphavirus replicase protein NSP1 induces filopodia and rearrangement of actin filaments. J Virol (1998) 1.15
Mapping the lipid distribution in the membranes of BHK cells (mini-review). Mol Membr Biol (1996) 1.13
Membrane binding mechanism of an RNA virus-capping enzyme. J Biol Chem (2000) 1.11
NMR structure and molecular dynamics of the in-plane membrane anchor of nonstructural protein 5A from bovine viral diarrhea virus. Biochemistry (2006) 1.11
Mechanisms governing subcellular localization and function of human RGS2. J Biol Chem (2001) 1.01
Testing the modularity of the N-terminal amphipathic helix conserved in picornavirus 2C proteins and hepatitis C NS5A protein. Virology (2005) 0.99
RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain. Traffic (2002) 0.99
Intensification of labelings of the immunogold silver staining method by gold toning. Brain Res Bull (1992) 0.87
A monotopic membrane protein goes solo. Structure (2006) 0.79
3D tomography reveals connections between the phagophore and endoplasmic reticulum. Autophagy (2009) 4.17
Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain-like mechanism. J Cell Biol (2007) 3.05
Composition and dynamics of human mitochondrial nucleoids. Mol Biol Cell (2003) 2.74
Endoplasmic reticulum remains continuous and undergoes sheet-to-tubule transformation during cell division in mammalian cells. J Cell Biol (2007) 2.24
VCIP135, a novel essential factor for p97/p47-mediated membrane fusion, is required for Golgi and ER assembly in vivo. J Cell Biol (2002) 2.06
p37 is a p97 adaptor required for Golgi and ER biogenesis in interphase and at the end of mitosis. Dev Cell (2006) 1.95
Intestinal microbiota in healthy adults: temporal analysis reveals individual and common core and relation to intestinal symptoms. PLoS One (2011) 1.88
Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains. J Virol (2006) 1.70
Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus. PLoS Pathog (2012) 1.69
Functions of alphavirus nonstructural proteins in RNA replication. Prog Nucleic Acid Res Mol Biol (2002) 1.66
Monitoring autophagy by electron microscopy in Mammalian cells. Methods Enzymol (2009) 1.66
Callose biosynthesis regulates symplastic trafficking during root development. Dev Cell (2011) 1.55
Properly folded nonstructural polyprotein directs the semliki forest virus replication complex to the endosomal compartment. J Virol (2003) 1.52
Phosphatidylinositol 3-kinase-, actin-, and microtubule-dependent transport of Semliki Forest Virus replication complexes from the plasma membrane to modified lysosomes. J Virol (2010) 1.52
Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase. Proc Natl Acad Sci U S A (2009) 1.51
Differential activities of cellular and viral macro domain proteins in binding of ADP-ribose metabolites. J Mol Biol (2008) 1.47
Polypurine (A)-rich sequences promote cross-kingdom conservation of internal ribosome entry. Proc Natl Acad Sci U S A (2002) 1.45
Inhibitors of alphavirus entry and replication identified with a stable Chikungunya replicon cell line and virus-based assays. PLoS One (2011) 1.37
Regulation of the sequential processing of Semliki Forest virus replicase polyprotein. J Biol Chem (2003) 1.34
The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket. J Virol (2009) 1.32
SH3 domain-mediated recruitment of host cell amphiphysins by alphavirus nsP3 promotes viral RNA replication. PLoS Pathog (2011) 1.32
Prostatic acid phosphatase is not a prostate specific target. Cancer Res (2007) 1.31
The localization and phosphorylation of p47 are important for Golgi disassembly-assembly during the cell cycle. J Cell Biol (2003) 1.29
Comparative metaproteomics and diversity analysis of human intestinal microbiota testifies for its temporal stability and expression of core functions. PLoS One (2012) 1.28
A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice. J Immunol (2012) 1.27
Progressive sheet-to-tubule transformation is a general mechanism for endoplasmic reticulum partitioning in dividing mammalian cells. Mol Biol Cell (2012) 1.25
A single amino acid change in the nuclear localization sequence of the nsP2 protein affects the neurovirulence of Semliki Forest virus. J Virol (2002) 1.23
Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection. Mol Biol Cell (2012) 1.22
Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice. J Virol (2013) 1.19
Viperin restricts chikungunya virus replication and pathology. J Clin Invest (2012) 1.16
Complex formation between hepatitis C virus NS2 and NS3 proteins. Virus Res (2005) 1.14
Pinkbar is an epithelial-specific BAR domain protein that generates planar membrane structures. Nat Struct Mol Biol (2011) 1.12
Complement activation associates with saccular cerebral artery aneurysm wall degeneration and rupture. Neurosurgery (2006) 1.11
Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus. J Gen Virol (2007) 1.09
Modulation of Aire regulates the expression of tissue-restricted antigens. Mol Immunol (2007) 1.07
Molecular determinants of substrate specificity for Semliki Forest virus nonstructural protease. J Virol (2006) 1.07
Semliki forest virus-induced endoplasmic reticulum stress accelerates apoptotic death of mammalian cells. J Virol (2010) 1.07
Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex. PLoS Pathog (2011) 1.05
Defective endocytic trafficking of NPC1 and NPC2 underlying infantile Niemann-Pick type C disease. Hum Mol Genet (2003) 1.05
Novel functions of the alphavirus nonstructural protein nsP3 C-terminal region. J Virol (2009) 1.05
Mutations in the nuclear localization signal of nsP2 influencing RNA synthesis, protein expression and cytotoxicity of Semliki Forest virus. J Gen Virol (2008) 1.05
Cell-to-cell spread of the RNA interference response suppresses Semliki Forest virus (SFV) infection of mosquito cell cultures and cannot be antagonized by SFV. J Virol (2009) 1.04
Inhibitors of virus replication: recent developments and prospects. Appl Microbiol Biotechnol (2004) 1.04
Assembly of alphavirus replication complexes from RNA and protein components in a novel trans-replication system in mammalian cells. J Virol (2011) 1.03
GDNF-deprived sympathetic neurons die via a novel nonmitochondrial pathway. J Cell Biol (2003) 1.03
MLN64 is involved in actin-mediated dynamics of late endocytic organelles. Mol Biol Cell (2005) 1.00
Therapeutics and vaccines against chikungunya virus. Vector Borne Zoonotic Dis (2015) 1.00
Mutations at the palmitoylation site of non-structural protein nsP1 of Semliki Forest virus attenuate virus replication and cause accumulation of compensatory mutations. J Gen Virol (2007) 0.98
Macromolecular assembly-driven processing of the 2/3 cleavage site in the alphavirus replicase polyprotein. J Virol (2011) 0.97
The structure of GFRalpha1 domain 3 reveals new insights into GDNF binding and RET activation. EMBO J (2004) 0.96
Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood. Sci Rep (2012) 0.96
How to bury the dead: elimination of apoptotic hair cells from the hearing organ of the mouse. J Assoc Res Otolaryngol (2014) 0.96
Obatoclax, saliphenylhalamide, and gemcitabine inhibit influenza a virus infection. J Biol Chem (2012) 0.94
Defective insulin receptor activation and altered lipid rafts in Niemann-Pick type C disease hepatocytes. Biochem J (2005) 0.94
Up-regulation of beta2 and alpha7 subunit containing nicotinic acetylcholine receptors in mouse striatum at cellular level. Eur J Neurosci (2005) 0.94
Template RNA length determines the size of replication complex spherules for Semliki Forest virus. J Virol (2013) 0.93
Secretion of sterols and the NPC2 protein from primary astrocytes. J Biol Chem (2004) 0.92
Construction, properties, and potential application of infectious plasmids containing Semliki Forest virus full-length cDNA with an inserted intron. J Virol Methods (2007) 0.92
Betulin-derived compounds as inhibitors of alphavirus replication. J Nat Prod (2009) 0.91
Characterization of the intracellular localization, processing, and secretion of two glial cell line-derived neurotrophic factor splice isoforms. J Neurosci (2010) 0.91
Properties of non-structural protein 1 of Semliki Forest virus and its interference with virus replication. J Gen Virol (2008) 0.91
Characterization of the cysteine protease domain of Semliki Forest virus replicase protein nsP2 by in vitro mutagenesis. FEBS Lett (2006) 0.90
Enzymatic defects of the nsP2 proteins of Semliki Forest virus temperature-sensitive mutants. J Virol (2007) 0.90
Functional cross-talk between distant domains of chikungunya virus non-structural protein 2 is decisive for its RNA-modulating activity. J Biol Chem (2014) 0.90
ER sheet persistence is coupled to myosin 1c-regulated dynamic actin filament arrays. Mol Biol Cell (2014) 0.89
Active and specific recruitment of a soluble cargo protein for endoplasmic reticulum exit in the absence of functional COPII component Sec24p. J Cell Sci (2004) 0.89
A luciferase-based screening method for inhibitors of alphavirus replication applied to nucleoside analogues. Antiviral Res (2008) 0.89
Structure-function analysis of severe acute respiratory syndrome coronavirus RNA cap guanine-N7-methyltransferase. J Virol (2013) 0.89
The C-terminal repeat domains of nsP3 from the Old World alphaviruses bind directly to G3BP. J Virol (2014) 0.89
Magnetic fractionation and proteomic dissection of cellular organelles occupied by the late replication complexes of Semliki Forest virus. J Virol (2013) 0.89
RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication. PLoS Pathog (2013) 0.88
Cholesterol substitution increases the structural heterogeneity of caveolae. J Biol Chem (2008) 0.88
Intracellular localization and effects of individually expressed human parechovirus 1 non-structural proteins. J Gen Virol (2007) 0.88
Ultrastructural relationship of the phagophore with surrounding organelles. Autophagy (2015) 0.87
Characterization and subcellular localization of human neutral class II alpha-mannosidase [corrected]. Glycobiology (2007) 0.86
Molecular defects caused by temperature-sensitive mutations in Semliki Forest virus nsP1. J Virol (2008) 0.84
Neurons and oligodendrocytes in the mouse brain differ in their ability to replicate Semliki Forest virus. J Neurovirol (2008) 0.84
Identification of mutations causing temperature-sensitive defects in Semliki Forest virus RNA synthesis. J Virol (2006) 0.84
Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout. Virol J (2013) 0.84
Golgi apparatus partitioning during cell division. Mol Membr Biol (2003) 0.83
Characterization of YIPF3 and YIPF4, cis-Golgi Localizing Yip domain family proteins. Cell Struct Funct (2011) 0.83
Early secretory pathway localization and lack of processing for hepatitis E virus replication protein pORF1. J Gen Virol (2012) 0.83
Presentation overrides specificity: probing the plasticity of alphaviral proteolytic activity through mutational analysis. J Virol (2013) 0.82