The type I interferon system protects mice from Semliki Forest virus by preventing widespread virus dissemination in extraneural tissues, but does not mediate the restricted replication of avirulent virus in central nervous system neurons.

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Published in J Gen Virol on December 01, 2007

Authors

Rennos Fragkoudis1, Lucy Breakwell, Clive McKimmie, Amanda Boyd, Gerald Barry, Alain Kohl, Andres Merits, John K Fazakerley

Author Affiliations

1: Virology, Centre for Infectious Diseases, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh EH19 1QH, UK.

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