Published in Nature on November 16, 2006
Toxicity and cellular uptake of gold nanoparticles: what we have learned so far? J Nanopart Res (2010) 2.70
The toxicity data landscape for environmental chemicals. Environ Health Perspect (2008) 2.68
The nanosilica hazard: another variable entity. Part Fibre Toxicol (2010) 2.38
Environmental behavior and ecotoxicity of engineered nanoparticles to algae, plants, and fungi. Ecotoxicology (2008) 2.30
Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping. ACS Nano (2010) 2.29
Carbon nanotubes degraded by neutrophil myeloperoxidase induce less pulmonary inflammation. Nat Nanotechnol (2010) 2.26
Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci U S A (2008) 2.04
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Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION). Nano Rev (2010) 1.88
Optimized dispersion of nanoparticles for biological in vitro and in vivo studies. Part Fibre Toxicol (2008) 1.79
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Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ Health Perspect (2013) 1.68
Length-dependent retention of carbon nanotubes in the pleural space of mice initiates sustained inflammation and progressive fibrosis on the parietal pleura. Am J Pathol (2011) 1.65
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Nanotechnology, nanotoxicology, and neuroscience. Prog Neurobiol (2008) 1.59
Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing. Environ Health Perspect (2010) 1.57
Potential for inhalation exposure to engineered nanoparticles from nanotechnology-based cosmetic powders. Environ Health Perspect (2012) 1.52
Nanotechnology in the real world: Redeveloping the nanomaterial consumer products inventory. Beilstein J Nanotechnol (2015) 1.51
Nanoparticle analysis and characterization methodologies in environmental risk assessment of engineered nanoparticles. Ecotoxicology (2008) 1.50
Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction. Part Fibre Toxicol (2008) 1.49
Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation. Environ Health Perspect (2008) 1.45
Nanotoxicology: characterizing the scientific literature, 2000-2007. J Nanopart Res (2008) 1.44
Surface modification-mediated biodistribution of (13)C-fullerene C60 in vivo. Part Fibre Toxicol (2016) 1.42
Airborne monitoring to distinguish engineered nanomaterials from incidental particles for environmental health and safety. J Occup Environ Hyg (2009) 1.33
Acute toxicity and prothrombotic effects of quantum dots: impact of surface charge. Environ Health Perspect (2008) 1.32
Identification of the mechanisms that drive the toxicity of TiO(2 )particulates: the contribution of physicochemical characteristics. Part Fibre Toxicol (2009) 1.23
Toxicity and environmental risks of nanomaterials: challenges and future needs. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2009) 1.22
Potential for exposure to engineered nanoparticles from nanotechnology-based consumer spray products. J Expo Sci Environ Epidemiol (2011) 1.21
Nanoparticles, human health hazard and regulation. J R Soc Interface (2009) 1.17
Surface properties dictate uptake, distribution, excretion, and toxicity of nanoparticles in fish. Small (2010) 1.16
Nanoparticles in the lung. Nat Biotechnol (2010) 1.14
Nanoparticle inhalation alters systemic arteriolar vasoreactivity through sympathetic and cyclooxygenase-mediated pathways. Nanotoxicology (2011) 1.12
Single nanoparticle detectors for biological applications. Nanoscale (2012) 1.10
New views on cellular uptake and trafficking of manufactured nanoparticles. J R Soc Interface (2013) 1.09
Manufactured aluminum oxide nanoparticles decrease expression of tight junction proteins in brain vasculature. J Neuroimmune Pharmacol (2008) 1.07
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Evaluation of iron oxide nanoparticle biocompatibility. Int J Nanomedicine (2011) 1.06
Delivery of antiinflammatory nutraceuticals by nanoparticles for the prevention and treatment of cancer. Biochem Pharmacol (2010) 1.05
Silver nanowire exposure results in internalization and toxicity to Daphnia magna. ACS Nano (2013) 1.05
IL-1R signalling is critical for regulation of multi-walled carbon nanotubes-induced acute lung inflammation in C57Bl/6 mice. Nanotoxicology (2012) 1.04
Intranasal exposure to amorphous nanosilica particles could activate intrinsic coagulation cascade and platelets in mice. Part Fibre Toxicol (2013) 1.03
Preparation of cells for assessing ultrastructural localization of nanoparticles with transmission electron microscopy. Nat Protoc (2010) 1.02
Nanoparticles as catalysts for protein fibrillation. Proc Natl Acad Sci U S A (2007) 1.00
Nanobiotechnology can boost crop production and quality: first evidence from increased plant biomass, fruit yield and phytomedicine content in bitter melon (Momordica charantia). BMC Biotechnol (2013) 0.99
Exposure to inhaled nickel nanoparticles causes a reduction in number and function of bone marrow endothelial progenitor cells. Inhal Toxicol (2010) 0.99
A general mechanism for intracellular toxicity of metal-containing nanoparticles. Nanoscale (2014) 0.98
Integrating zebrafish toxicology and nanoscience for safer product development. Green Chem (2013) 0.98
Nanotherapeutics in the EU: an overview on current state and future directions. Int J Nanomedicine (2014) 0.97
Zebrafish: an in vivo model for nano EHS studies. Small (2012) 0.96
'Safe handling of nanotechnology' ten years on. Nat Nanotechnol (2016) 0.96
Multidisciplinary Engagement with Nanoethics Through Education-The Nanobio-RAISE Advanced Courses as a Case Study and Model. Nanoethics (2009) 0.95
The new deficit model. Nat Nanotechnol (2009) 0.95
Cellular entry of nanoparticles via serum sensitive clathrin-mediated endocytosis, and plasma membrane permeabilization. Int J Nanomedicine (2012) 0.95
Phytosynthesis of nanoparticles: concept, controversy and application. Nanoscale Res Lett (2014) 0.95
Biomechanical effects of environmental and engineered particles on human airway smooth muscle cells. J R Soc Interface (2010) 0.94
Preparation and Characterization Challenges to Understanding Environmental and Biological Impacts of Nanoparticles. Surf Interface Anal (2012) 0.94
Nanotechnology research: applications in nutritional sciences. J Nutr (2009) 0.92
Physicochemical properties of nanomaterials: implication in associated toxic manifestations. Biomed Res Int (2014) 0.92
A 21st century paradigm for evaluating the health hazards of nanoscale materials? Toxicol Sci (2009) 0.91
Molecular imaging in cardiovascular disease: targets and opportunities. Nat Rev Cardiol (2009) 0.91
Stoichiometry and Structure of Poly(amidoamine) Dendrimer-Lipid Complexes. ACS Nano (2009) 0.90
In vitro interaction of colloidal nanoparticles with mammalian cells: What have we learned thus far? Beilstein J Nanotechnol (2014) 0.90
Direct observation of a single nanoparticle-ubiquitin corona formation. Nanoscale (2013) 0.90
The Nanomaterial Registry: facilitating the sharing and analysis of data in the diverse nanomaterial community. Int J Nanomedicine (2013) 0.90
Particle-induced artifacts in the MTT and LDH viability assays. Chem Res Toxicol (2012) 0.89
Murine pulmonary responses after sub-chronic exposure to aluminum oxide-based nanowhiskers. Part Fibre Toxicol (2012) 0.89
Nanotechnology and exposure science: what is needed to fill the research and data gaps for consumer products. Int J Occup Environ Health (2011) 0.89
New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformatics. J Toxicol Environ Health B Crit Rev (2012) 0.88
Pulmonary surfactant is indispensable in order to simulate the in vivo situation. Part Fibre Toxicol (2013) 0.88
Effects of titanium dioxide nanoparticle exposure on neuroimmune responses in rat airways. J Toxicol Environ Health A (2010) 0.88
The eNanoMapper database for nanomaterial safety information. Beilstein J Nanotechnol (2015) 0.87
Ethics in nanomedicine. Nanomedicine (Lond) (2007) 0.87
Bottom-up risk regulation? How nanotechnology risk knowledge gaps challenge federal and state environmental agencies. Environ Manage (2008) 0.87
Toxicological effect of engineered nanomaterials on the liver. Br J Pharmacol (2014) 0.87
Fluorescent nanocrystals reveal regulated portals of entry into and between the cells of Hydra. PLoS One (2009) 0.86
Quantitative characterization of agglomerates and aggregates of pyrogenic and precipitated amorphous silica nanomaterials by transmission electron microscopy. J Nanobiotechnology (2012) 0.85
Engineering nanomedicines for improved melanoma therapy: progress and promises. Nanomedicine (Lond) (2010) 0.85
CdSe quantum dot (QD)-induced morphological and functional impairments to liver in mice. PLoS One (2011) 0.85
Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy. Sci Rep (2012) 0.85
Considerations on occupational medical surveillance in employees handling nanoparticles. Int Arch Occup Environ Health (2007) 0.85
Cytotoxicity of subtoxic AgNP in human hepatoma cell line (HepG2) after long-term exposure. Iran Biomed J (2010) 0.85
Real-time single airborne nanoparticle detection with nanomechanical resonant filter-fiber. Sci Rep (2013) 0.84
Mechanisms of Toxicity of Ag Nanoparticles in Comparison to Bulk and Ionic Ag on Mussel Hemocytes and Gill Cells. PLoS One (2015) 0.84
Hepatic toxicology following single and multiple exposure of engineered nanomaterials utilising a novel primary human 3D liver microtissue model. Part Fibre Toxicol (2014) 0.83
Biocompatibility of polymer grafted core/shell iron/carbon nanoparticles. Biomaterials (2010) 0.83
Extracellular polymeric substances (EPS) of freshwater biofilms stabilize and modify CeO2 and Ag nanoparticles. PLoS One (2014) 0.83
Effect of nanoparticles exposure on fractional exhaled nitric oxide (FENO) in workers exposed to nanomaterials. Int J Mol Sci (2014) 0.83
Effects of engineered nanoparticles on the assembly of exopolymeric substances from phytoplankton. PLoS One (2011) 0.83
Regulation of plasminogen activator inhibitor-1 expression in endothelial cells with exposure to metal nanoparticles. Toxicol Lett (2010) 0.83
TOXICITY PROFILING OF ENGINEERED NANOMATERIALS VIA MULTIVARIATE DOSE-RESPONSE SURFACE MODELING. Ann Appl Stat (2012) 0.83
Application of vitamin E to antagonize SWCNTs-induced exacerbation of allergic asthma. Sci Rep (2014) 0.82
Protein corona - from molecular adsorption to physiological complexity. Beilstein J Nanotechnol (2015) 0.82
Proteomic analysis of early response lymph node proteins in mice treated with titanium dioxide nanoparticles. J Proteomics (2011) 0.82
The acute exposure effects of inhaled nickel nanoparticles on murine endothelial progenitor cells. Inhal Toxicol (2014) 0.82
Redefining risk research priorities for nanomaterials. J Nanopart Res (2009) 0.81
ONE Nano: NIEHS's strategic initiative on the health and safety effects of engineered nanomaterials. Environ Health Perspect (2013) 0.81
Molecular toxicity of cerium oxide nanoparticles to the freshwater alga Chlamydomonas reinhardtii is associated with supra-environmental exposure concentrations. Nanotoxicology (2015) 0.80
Airborne manufactured nano-objects released from commercially available spray products: temporal and spatial influences. J Expo Sci Environ Epidemiol (2013) 0.80
Nanomaterial-Enabled Neural Stimulation. Front Neurosci (2016) 0.80
Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol (2008) 10.77
From anchovies to sardines and back: multidecadal change in the Pacific Ocean. Science (2003) 7.24
Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Part Fibre Toxicol (2005) 6.04
Cytotoxicity of nanoparticles. Small (2008) 5.63
Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease. N Engl J Med (2007) 4.98
Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis. Circulation (2005) 4.71
Sample design and cohort selection in the Hispanic Community Health Study/Study of Latinos. Ann Epidemiol (2010) 4.10
Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol Sci (2006) 4.02
Global association of air pollution and heart failure: a systematic review and meta-analysis. Lancet (2013) 3.57
The potential risks of nanomaterials: a review carried out for ECETOC. Part Fibre Toxicol (2006) 3.56
Maternal vitamin D intake during pregnancy and early childhood wheezing. Am J Clin Nutr (2007) 3.40
Public health benefits of strategies to reduce greenhouse-gas emissions: health implications of short-lived greenhouse pollutants. Lancet (2009) 3.22
Translocation of inhaled ultrafine manganese oxide particles to the central nervous system. Environ Health Perspect (2006) 3.16
Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure. Part Fibre Toxicol (2005) 3.12
Adverse cardiovascular effects of air pollution. Nat Clin Pract Cardiovasc Med (2008) 3.00
Persistent endothelial dysfunction in humans after diesel exhaust inhalation. Am J Respir Crit Care Med (2007) 2.65
Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles. Toxicol Sci (2007) 2.65
Evaluating the toxicity of airborne particulate matter and nanoparticles by measuring oxidative stress potential--a workshop report and consensus statement. Inhal Toxicol (2008) 2.53
Diet as a risk factor for atopy and asthma. J Allergy Clin Immunol (2005) 2.47
Vascular targeted nanoparticles for imaging and treatment of brain tumors. Clin Cancer Res (2006) 2.46
A review of the in vivo and in vitro toxicity of silver and gold particulates: particle attributes and biological mechanisms responsible for the observed toxicity. Crit Rev Toxicol (2010) 2.38
Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol Appl Pharmacol (2007) 2.37
The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area. Occup Environ Med (2007) 2.29
Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10). Free Radic Biol Med (2003) 2.28
Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles. Toxicol Sci (2003) 2.26
Correlating nanoscale titania structure with toxicity: a cytotoxicity and inflammatory response study with human dermal fibroblasts and human lung epithelial cells. Toxicol Sci (2006) 2.23
Prevalence and sociodemographic correlates of antinuclear antibodies in the United States. Arthritis Rheum (2012) 2.09
Ultrafine particle deposition in humans during rest and exercise. Inhal Toxicol (2003) 2.06
Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity. Inhal Toxicol (2007) 2.06
Reducing personal exposure to particulate air pollution improves cardiovascular health in patients with coronary heart disease. Environ Health Perspect (2012) 2.05
The pulmonary toxicology of ultrafine particles. J Aerosol Med (2002) 2.02
Real-time measurements of dissolved oxygen inside live cells by organically modified silicate fluorescent nanosensors. Anal Chem (2004) 1.97
Interactions between ultrafine particles and transition metals in vivo and in vitro. Toxicol Appl Pharmacol (2002) 1.88
Diesel exhaust inhalation does not affect heart rhythm or heart rate variability. Heart (2010) 1.84
The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types. Inhal Toxicol (2003) 1.83
Combustion-derived nanoparticulate induces the adverse vascular effects of diesel exhaust inhalation. Eur Heart J (2011) 1.79
Development of a real-time RT-PCR for the detection of swine-lineage influenza A (H1N1) virus infections. J Clin Virol (2009) 1.78
Size dependence of the translocation of inhaled iridium and carbon nanoparticle aggregates from the lung of rats to the blood and secondary target organs. Inhal Toxicol (2009) 1.78
The field of tissue injury in the lung and airway. Cancer Prev Res (Phila) (2008) 1.77
Ultrafine particles in the urban air: to the respiratory tract--and beyond? Environ Health Perspect (2002) 1.76
Do inhaled carbon nanoparticles translocate directly into the circulation in humans? Am J Respir Crit Care Med (2005) 1.72
The new toxicology of sophisticated materials: nanotoxicology and beyond. Toxicol Sci (2010) 1.71
Inflammatory effects of coarse and fine particulate matter in relation to chemical and biological constituents. Toxicol Appl Pharmacol (2004) 1.70
The influence of protein adsorption on nanoparticle association with cultured endothelial cells. Biomaterials (2008) 1.68
Brain cancer diagnosis and therapy with nanoplatforms. Adv Drug Deliv Rev (2006) 1.66
Efficient elimination of inhaled nanoparticles from the alveolar region: evidence for interstitial uptake and subsequent reentrainment onto airways epithelium. Environ Health Perspect (2007) 1.65
Radon, smoking, and lung cancer: the need to refocus radon control policy. Am J Public Health (2013) 1.65
Length-dependent retention of carbon nanotubes in the pleural space of mice initiates sustained inflammation and progressive fibrosis on the parietal pleura. Am J Pathol (2011) 1.65
Meeting report: hazard assessment for nanoparticles--report from an interdisciplinary workshop. Environ Health Perspect (2007) 1.64
Does Nanoparticle Activity Depend upon Size and Crystal Phase? Nanotoxicology (2008) 1.62
Concept of assessing nanoparticle hazards considering nanoparticle dosemetric and chemical/biological response metrics. J Toxicol Environ Health A (2010) 1.61
Hazard and risk assessment of a nanoparticulate cerium oxide-based diesel fuel additive - a case study. Inhal Toxicol (2008) 1.60
Current hypotheses on the mechanisms of toxicity of ultrafine particles. Ann Ist Super Sanita (2003) 1.58
Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing. Environ Health Perspect (2010) 1.57
A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: The contribution of physico-chemical characteristics. Nanotoxicology (2010) 1.56
Photodynamic characterization and in vitro application of methylene blue-containing nanoparticle platforms. Photochem Photobiol (2005) 1.56
Delayed neuropsychologic dysfunction after liver transplantation for acute liver failure: a matched, case-controlled study. Liver Transpl (2002) 1.52
Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environ Health Perspect (2013) 1.52
Low maternal vitamin E intake during pregnancy is associated with asthma in 5-year-old children. Am J Respir Crit Care Med (2006) 1.51
The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line. Toxicol Appl Pharmacol (2008) 1.50
Correlating physico-chemical with toxicological properties of nanoparticles: the present and the future. ACS Nano (2010) 1.49
Migration of intradermally injected quantum dots to sentinel organs in mice. Toxicol Sci (2007) 1.48
Soluble transition metals cause the pro-inflammatory effects of welding fumes in vitro. Toxicol Appl Pharmacol (2004) 1.47
Graphene-based nanoplatelets: a new risk to the respiratory system as a consequence of their unusual aerodynamic properties. ACS Nano (2012) 1.46
Pulmonary function, diffusing capacity, and inflammation in healthy and asthmatic subjects exposed to ultrafine particles. Inhal Toxicol (2004) 1.45
Exposure to concentrated ambient particles does not affect vascular function in patients with coronary heart disease. Environ Health Perspect (2008) 1.45
Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation. Environ Health Perspect (2008) 1.45
Beneficial cardiovascular effects of reducing exposure to particulate air pollution with a simple facemask. Part Fibre Toxicol (2009) 1.45
Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humans. Environ Health Perspect (2006) 1.44
Research strategies for safety evaluation of nanomaterials, part IV: risk assessment of nanoparticles. Toxicol Sci (2005) 1.42
Skin exposure to micro- and nano-particles can cause haemostasis in zebrafish larvae. Thromb Haemost (2010) 1.41
Area under the curve as a dose metric for promotional responses following 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. Toxicol Appl Pharmacol (2003) 1.41
Ultrafine particle deposition in subjects with asthma. Environ Health Perspect (2004) 1.40
Absolute estimation of initial concentrations of amplicon in a real-time RT-PCR process. BMC Bioinformatics (2007) 1.40
Risks of smallpox vaccination: 200 years after Jenner. J Allergy Clin Immunol (2003) 1.39
Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes. Part Fibre Toxicol (2011) 1.38
Minimal analytical characterization of engineered nanomaterials needed for hazard assessment in biological matrices. Nanotoxicology (2010) 1.38
"Nanosized voltmeter" enables cellular-wide electric field mapping. Biophys J (2007) 1.37
Nanoparticles for two-photon photodynamic therapy in living cells. Nano Lett (2006) 1.37
The mechanism of pleural inflammation by long carbon nanotubes: interaction of long fibres with macrophages stimulates them to amplify pro-inflammatory responses in mesothelial cells. Part Fibre Toxicol (2012) 1.31
Air pollution and atherothrombosis. Inhal Toxicol (2007) 1.30
Effects of subchronically inhaled carbon black in three species. I. Retention kinetics, lung inflammation, and histopathology. Toxicol Sci (2005) 1.30
The rat ear vein model for investigating in vivo thrombogenicity of ultrafine particles (UFP). Toxicol Sci (2005) 1.29
Evaluation of toxic equivalency factors for induction of cytochromes P450 CYP1A1 and CYP1A2 enzyme activity by dioxin-like compounds. Toxicol Appl Pharmacol (2004) 1.29