PubRank

Bogdan I Florea

Author PubWeight™ 43.87‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4. Proc Natl Acad Sci U S A 2006 2.71
2 Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division. Immunity 2011 2.34
3 A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. Chem Biol 2006 1.54
4 Ultrasensitive in situ visualization of active glucocerebrosidase molecules. Nat Chem Biol 2010 1.26
5 Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib. Chem Biol 2011 1.13
6 Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors. Org Biomol Chem 2007 1.07
7 The Ku80 carboxy terminus stimulates joining and artemis-mediated processing of DNA ends. Mol Cell Biol 2008 1.03
8 Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain. Angew Chem Int Ed Engl 2013 1.01
9 Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment. Proc Natl Acad Sci U S A 2009 0.98
10 Syringolin A selectively labels the 20 S proteasome in murine EL4 and wild-type and bortezomib-adapted leukaemic cell lines. Chembiochem 2009 0.97
11 Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS. Nat Protoc 2013 0.96
12 Nature of pharmacophore influences active site specificity of proteasome inhibitors. J Biol Chem 2010 0.94
13 Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes. Bioorg Med Chem Lett 2007 0.94
14 Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites. J Med Chem 2013 0.92
15 Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo. Angew Chem Int Ed Engl 2012 0.92
16 Activity-based protein profiling: an enabling technology in chemical biology research. Curr Opin Chem Biol 2012 0.91
17 Bioorthogonal chemistry: applications in activity-based protein profiling. Acc Chem Res 2011 0.91
18 Assessing subunit dependency of the Plasmodium proteasome using small molecule inhibitors and active site probes. ACS Chem Biol 2014 0.90
19 Azido-BODIPY acid reveals quantitative Staudinger-Bertozzi ligation in two-step activity-based proteasome profiling. Chembiochem 2008 0.90
20 A panel of subunit-selective activity-based proteasome probes. Org Biomol Chem 2010 0.89
21 The natural product hybrid of Syringolin A and Glidobactin A synergizes proteasome inhibition potency with subsite selectivity. Chem Commun (Camb) 2010 0.88
22 Triple bioorthogonal ligation strategy for simultaneous labeling of multiple enzymatic activities. Angew Chem Int Ed Engl 2012 0.88
23 Potent and selective activity-based probes for GH27 human retaining α-galactosidases. J Am Chem Soc 2014 0.86
24 Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites. J Med Chem 2010 0.85
25 Transport and local metabolism of budesonide and fluticasone propionate in a human bronchial epithelial cell line (Calu-3). J Pharm Sci 2002 0.84
26 Identification of glucose kinase-dependent and -independent pathways for carbon control of primary metabolism, development and antibiotic production in Streptomyces coelicolor by quantitative proteomics. Mol Microbiol 2012 0.83
27 Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: a comparative study. Bioorg Med Chem 2011 0.83
28 Apoptosis induced by extracellular ATP in the mouse neuroblastoma cell line N1E-115: studies on involvement of P2 receptors and adenosine. Biochem Pharmacol 2002 0.83
29 The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains. Chem Biol 2012 0.83
30 A cleavable linker based on the levulinoyl ester for activity-based protein profiling. Angew Chem Int Ed Engl 2010 0.83
31 Proteomic identification of in vivo interactors reveals novel function of skin cornification proteins. J Proteome Res 2012 0.82
32 Two-step labeling of endogenous enzymatic activities by Diels-Alder ligation. Chembiochem 2010 0.81
33 Discovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones. Org Biomol Chem 2011 0.81
34 Peptido sulfonyl fluorides as new powerful proteasome inhibitors. J Med Chem 2012 0.81
35 Receptor-mediated targeting of cathepsins in professional antigen presenting cells. Angew Chem Int Ed Engl 2009 0.80
36 O-GlcNAc peptide epoxyketones are recognized by mammalian proteasomes. J Am Chem Soc 2009 0.79
37 Toward understanding induction of oxidative stress and apoptosis by proteasome inhibitors. Antioxid Redox Signal 2014 0.78
38 Chemical proteomics profiling of proteasome activity. Methods Mol Biol 2006 0.78
39 Identification and isolation of lantibiotics from culture: a bioorthogonal chemistry approach. Org Biomol Chem 2012 0.77
40 Proteasome selectivity towards Michael acceptor containing oligopeptide-based inhibitors. Org Biomol Chem 2010 0.77
41 Targeted pH-dependent fluorescent activity-based cathepsin probes. Chem Commun (Camb) 2011 0.77
42 Probing the proteasome cavity in three steps: bio-orthogonal photo-reactive suicide substrates. Chem Commun (Camb) 2010 0.77
43 Development of an acid ceramidase activity-based probe. Chem Commun (Camb) 2015 0.77
44 Bodipy-VAD-Fmk, a useful tool to study yeast peptide N-glycanase activity. Org Biomol Chem 2007 0.76
45 Development and application of an in vitro apoptin kinase assay. Anal Biochem 2011 0.76
46 Activity-based profiling of 2-oxoglutarate oxygenases. Chem Biol 2011 0.75
47 Correction to "Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes". ACS Cent Sci 2017 0.75
48 Identification of glucose kinase-dependent and -independent pathways for carbon control of primary metabolism, development and antibiotic production in Streptomyces coelicolor by quantitative proteomics. Mol Microbiol 2017 0.75
49 Stabilization of glucocerebrosidase by active-site occupancy. ACS Chem Biol 2017 0.75
50 Phosphate promotes the recovery of Mycobacterium tuberculosis β-lactamase from clavulanic acid inhibition. Biochemistry 2017 0.75
51 Sugar amino acid based peptide epoxyketones as potential proteasome inhibitors. Bioorg Chem 2010 0.75
52 Use of proteasome inhibitors. Curr Protoc Immunol 2015 0.75