Published in Neurochem Res on November 18, 2006
Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial. Nutr Metab (Lond) (2009) 1.79
Cerebral metabolic adaptation and ketone metabolism after brain injury. J Cereb Blood Flow Metab (2007) 1.70
Mitochondria, oxidative stress, and temporal lobe epilepsy. Epilepsy Res (2009) 1.37
Ketone bodies as a therapeutic for Alzheimer's disease. Neurotherapeutics (2008) 1.08
Ketogenic diet improves forelimb motor function after spinal cord injury in rodents. PLoS One (2013) 0.93
Neuroprotection by acetoacetate and β-hydroxybutyrate against NMDA-induced RGC damage in rat--possible involvement of kynurenic acid. Graefes Arch Clin Exp Ophthalmol (2010) 0.89
Clinical review: ketones and brain injury. Crit Care (2011) 0.87
Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic Treatments. Front Neurosci (2017) 0.86
Hydroxybutyrate prevents protein aggregation in the halotolerant bacterium Pseudomonas sp. CT13 under abiotic stress. Extremophiles (2012) 0.85
Protection of hypoglycemia-induced neuronal death by β-hydroxybutyrate involves the preservation of energy levels and decreased production of reactive oxygen species. J Cereb Blood Flow Metab (2015) 0.84
Effects of hypoglycaemia on neuronal metabolism in the adult brain: role of alternative substrates to glucose. J Inherit Metab Dis (2012) 0.84
Changes in ascorbate, glutathione and α-tocopherol concentrations in the brain regions during normal development and moderate hypoglycemia in rats. Neurosci Lett (2014) 0.79
Degeneration of spinal motor neurons by chronic AMPA-induced excitotoxicity in vivo and protection by energy substrates. Acta Neuropathol Commun (2015) 0.75
Excitotoxic neuronal death and the pathogenesis of Huntington's disease. Arch Med Res (2008) 1.29
Role of glutamate transporters in the clearance and release of glutamate during ischemia and its relation to neuronal death. Arch Med Res (2006) 1.11
Antioxidant capacity contributes to protection of ketone bodies against oxidative damage induced during hypoglycemic conditions. Exp Neurol (2008) 1.06
Calcium-dependent production of reactive oxygen species is involved in neuronal damage induced during glycolysis inhibition in cultured hippocampal neurons. J Neurosci Res (2008) 1.04
Glutamate toxicity in the striatum of the R6/2 Huntington's disease transgenic mice is age-dependent and correlates with decreased levels of glutamate transporters. Neurobiol Dis (2009) 0.99
Inhibition of Wnt and PI3K signaling modulates GSK-3beta activity and induces morphological changes in cortical neurons: role of tau phosphorylation. Neurochem Res (2008) 0.95
Disruption of endoplasmic reticulum calcium stores is involved in neuronal death induced by glycolysis inhibition in cultured hippocampal neurons. J Neurosci Res (2005) 0.89
Neuronal damage and cognitive impairment associated with hypoglycemia: An integrated view. Neurochem Int (2013) 0.88
Glucose deprivation induces reticulum stress by the PERK pathway and caspase-7- and calpain-mediated caspase-12 activation. Apoptosis (2014) 0.88
Role of oxidative stress on beta-amyloid neurotoxicity elicited during impairment of energy metabolism in the hippocampus: protection by antioxidants. Exp Neurol (2006) 0.87
Activation of NOX2 by the stimulation of ionotropic and metabotropic glutamate receptors contributes to glutamate neurotoxicity in vivo through the production of reactive oxygen species and calpain activation. J Neuropathol Exp Neurol (2011) 0.86
beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease. Exp Neurol (2002) 0.85
Brain amino acids during hyponatremia in vivo: clinical observations and experimental studies. Neurochem Res (2004) 0.84
Increased mitochondrial respiration maintains the mitochondrial membrane potential and promotes survival of cerebellar neurons in an endogenous model of glutamate receptor activation. J Neurochem (2005) 0.82
Heme oxygenase-1 induction prevents neuronal damage triggered during mitochondrial inhibition: role of CO and bilirubin. Int J Biochem Cell Biol (2008) 0.81
Glycolysis inhibition decreases the levels of glutamate transporters and enhances glutamate neurotoxicity in the R6/2 Huntington's disease mice. Neurochem Res (2010) 0.81
Neuroprotective role of heme-oxygenase 1 against iodoacetate-induced toxicity in rat cerebellar granule neurons: Role of bilirubin. Free Radic Res (2009) 0.79
Calpain activation induced by glucose deprivation is mediated by oxidative stress and contributes to neuronal damage. Int J Biochem Cell Biol (2013) 0.79
Okadaic acid induces epileptic seizures and hyperphosphorylation of the NR2B subunit of the NMDA receptor in rat hippocampus in vivo. Exp Neurol (2002) 0.78
Contribution of NMDA and non-NMDA receptors to in vivo glutamate-induced calpain activation in the rat striatum. Relation to neuronal damage. Neurochem Res (2008) 0.78
Calpain activation is involved in acute manganese neurotoxicity in the rat striatum in vivo. Exp Neurol (2011) 0.78
The effect of nordihydroguaiaretic acid on iodoacetate-induced toxicity in cultured neurons. J Biochem Mol Toxicol (2009) 0.78
Mild mitochondrial inhibition in vivo enhances glutamate-induced neuronal damage through calpain but not caspase activation: role of ionotropic glutamate receptors. Exp Neurol (2008) 0.77
Glutamate uptake inhibitor L-trans-pyrrolidine 2,4-dicarboxylate becomes neurotoxic in the presence of subthreshold concentrations of mitochondrial toxin 3-nitropropionate: involvement of mitochondrial reducing activity and ATP production. J Neurosci Res (2003) 0.76
Neuroprotective role of estradiol against neuronal death induced by glucose deprivation in cultured rat hippocampal neurons. Neuroendocrinology (2011) 0.76
Differential production of reactive oxygen species in distinct brain regions of hypoglycemic mice. Metab Brain Dis (2014) 0.76
Cerebellar granule neurons are more vulnerable to transient transport-mediated glutamate release than to glutamate uptake blockade. correlation with excitatory amino acids levels. Neurochem Res (2007) 0.75