Published in Blood on April 01, 2007
A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat Immunol (2008) 6.78
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity. Nat Immunol (2009) 4.28
Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells. Nat Immunol (2009) 3.82
Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. Nat Immunol (2009) 3.79
Innate cells and T helper 2 cell immunity in airway inflammation. Immunity (2009) 1.94
Genetic analysis of basophil function in vivo. Nat Immunol (2011) 1.82
Newly discovered roles for basophils: a neglected minority gains new respect. Nat Rev Immunol (2009) 1.56
Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells. Blood (2014) 1.47
Matrix metalloproteinase-2 conditions human dendritic cells to prime inflammatory T(H)2 cells via an IL-12- and OX40L-dependent pathway. Cancer Cell (2011) 1.22
Fc receptor gamma-chain, a constitutive component of the IL-3 receptor, is required for IL-3-induced IL-4 production in basophils. Nat Immunol (2008) 1.16
Basophils and type 2 immunity. Curr Opin Hematol (2008) 1.16
Innate immune cells in liver inflammation. Mediators Inflamm (2012) 1.11
Role of basophils in the initiation of Th2 responses. Curr Opin Immunol (2010) 1.10
Endolysosomal proteases and their inhibitors in immunity. Nat Rev Immunol (2009) 1.10
New insights into basophil biology: initiators, regulators, and effectors of type 2 inflammation. Ann N Y Acad Sci (2011) 1.00
STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection. J Immunol (2009) 0.94
Reduced FcepsilonRI-mediated release of asthma-promoting cytokines and chemokines from human basophils during omalizumab therapy. Int Arch Allergy Immunol (2009) 0.92
Functional heterogeneity in the basophil cell lineage. Adv Immunol (2012) 0.92
Accumulation of eosinophils in intestine-draining mesenteric lymph nodes occurs after Trichuris muris infection. Parasite Immunol (2011) 0.91
Basophils control T-cell responses and limit disease activity in experimental murine colitis. Mucosal Immunol (2013) 0.91
Induction of type 2 responses by schistosome worms during prepatent infection. J Infect Dis (2010) 0.90
Basophils and autoreactive IgE in the pathogenesis of systemic lupus erythematosus. Curr Allergy Asthma Rep (2011) 0.89
Basophils, IgE, and autoantibody-mediated kidney disease. J Immunol (2011) 0.88
Key mediators in the immunopathogenesis of allergic asthma. Int Immunopharmacol (2014) 0.84
Ikaros limits basophil development by suppressing C/EBP-α expression. Blood (2013) 0.83
Basophil-derived IL-4 plays versatile roles in immunity. Semin Immunopathol (2016) 0.82
Host basophils are dispensable for induction of donor T helper 2 cell differentiation and severity of experimental graft-versus-host disease. Biol Blood Marrow Transplant (2011) 0.81
Basophils inhibit proliferation of CD4⁺ T cells in autologous and allogeneic mixed lymphocyte reactions and limit disease activity in a murine model of graft versus host disease. Immunology (2015) 0.80
Transcriptional regulation of mast cell and basophil lineage commitment. Semin Immunopathol (2016) 0.80
Basophils help establish protective immunity induced by irradiated larval vaccination for filariasis. Vaccine (2013) 0.78
Role of basophils in rheumatoid arthritis (Review). Exp Ther Med (2015) 0.78
Mutual Interaction of Basophils and T Cells in Chronic Inflammatory Diseases. Front Immunol (2015) 0.78
Neonatal Basophils Stifle the Function of Early-Life Dendritic Cells To Curtail Th1 Immunity in Newborn Mice. J Immunol (2015) 0.78
Trogocytosis of peptide-MHC class II complexes from dendritic cells confers antigen-presenting ability on basophils. Proc Natl Acad Sci U S A (2017) 0.77
Basophil count, a marker for disease activity in systemic lupus erythematosus. Clin Rheumatol (2014) 0.77
Neonatal Immunization with a Single IL-4/Antigen Dose Induces Increased Antibody Responses after Challenge Infection with Equine Herpesvirus Type 1 (EHV-1) at Weanling Age. PLoS One (2017) 0.75
The effect of stimuli on basophil-mediated atopic responses during asthmatic lying-in women and in newborns. Hybridoma (Larchmt) (2012) 0.75
Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses. Nat Immunol (2004) 4.41
Uncultivated bacteria as etiologic agents of intra-amniotic inflammation leading to preterm birth. J Clin Microbiol (2008) 2.45
Differential T cell function and fate in lymph node and nonlymphoid tissues. J Exp Med (2002) 2.14
A critical role for IRAK4 kinase activity in Toll-like receptor-mediated innate immunity. J Exp Med (2007) 2.03
Growth factor independent-1 induced by IL-4 regulates Th2 cell proliferation. Immunity (2002) 1.99
Cutaneous immunosurveillance and regulation of inflammation by group 2 innate lymphoid cells. Nat Immunol (2013) 1.91
Loss of enigma homolog protein results in dilated cardiomyopathy. Circ Res (2010) 1.85
HIV infection and sexually transmitted diseases in female commercial sex workers in China. J Acquir Immune Defic Syndr (2005) 1.72
Animal model of Nippostrongylus brasiliensis and Heligmosomoides polygyrus. Curr Protoc Immunol (2003) 1.70
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation. Immunity (2010) 1.64
In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation. Proc Natl Acad Sci U S A (2008) 1.60
Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells. J Immunol (2008) 1.54
Can bacterial endotoxin exposure reverse atopy and atopic disease? J Allergy Clin Immunol (2004) 1.54
Hydrogen peroxide inhibits mTOR signaling by activation of AMPKalpha leading to apoptosis of neuronal cells. Lab Invest (2010) 1.52
CD4 T cells play important roles in maintaining IL-17-producing γδ T-cell subsets in naive animals. Immunol Cell Biol (2011) 1.50
Simvastatin suppresses apoptosis in vulnerable atherosclerotic plaques through regulating the expression of p(53), Bcl-2 and Bcl-xL. Cardiovasc Drugs Ther (2012) 1.46
Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity. J Biol Chem (2010) 1.44
Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism. J Immunol (2010) 1.39
c-Jun NH(2)-terminal kinase (JNK)1 and JNK2 have distinct roles in CD8(+) T cell activation. J Exp Med (2002) 1.38
Epithelial cell-specific Act1 adaptor mediates interleukin-25-dependent helminth expulsion through expansion of Lin(-)c-Kit(+) innate cell population. Immunity (2012) 1.34
T cell-derived IL-3 plays key role in parasite infection-induced basophil production but is dispensable for in vivo basophil survival. Int Immunol (2008) 1.30
Concomitant regulation of T-cell activation and homeostasis. Nat Rev Immunol (2004) 1.29
Nonredundant roles for CD1d-restricted natural killer T cells and conventional CD4+ T cells in the induction of immunoglobulin E antibodies in response to interleukin 18 treatment of mice. J Exp Med (2003) 1.28
Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death. Free Radic Biol Med (2010) 1.28
Immune regulation of protease-activated receptor-1 expression in murine small intestine during Nippostrongylus brasiliensis infection. J Immunol (2005) 1.27
PPM1A and PPM1B act as IKKbeta phosphatases to terminate TNFalpha-induced IKKbeta-NF-kappaB activation. Cell Signal (2008) 1.23
Redox regulation of interleukin-4 signaling. Immunity (2008) 1.20
The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response. J Immunol (2009) 1.19
Seasonal variations in notification of active tuberculosis cases in China, 2005-2012. PLoS One (2013) 1.17
Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network. PLoS One (2011) 1.15
Basophils are the major producers of IL-4 during primary helminth infection. J Immunol (2011) 1.14
[Ruthenium(II)(bpy)(2)L](2+), where L are imidazo[f]-1,10-phenanthrolines: synthesis, photophysics and binding with DNA. Spectrochim Acta A Mol Biomol Spectrosc (2004) 1.13
Cutting edge: Generation of colitogenic Th17 CD4 T cells is enhanced by IL-17+ γδ T cells. J Immunol (2011) 1.13
Mutations of 60 known causative genes in 157 families with retinitis pigmentosa based on exome sequencing. Hum Genet (2014) 1.13
Antigen challenge leads to in vivo activation and elimination of highly polarized TH1 memory T cells. Proc Natl Acad Sci U S A (2002) 1.09
Clusters of sudden unexplained death associated with the mushroom, Trogia venenata, in rural Yunnan Province, China. PLoS One (2012) 1.09
Dual transcriptional activator and repressor roles of TBX20 regulate adult cardiac structure and function. Hum Mol Genet (2012) 1.08
The lung is an important site for priming CD4 T-cell-mediated protective immunity against gastrointestinal helminth parasites. Infect Immun (2010) 1.07
Nucleo-cytoplasmic shuttling of PAK4 modulates β-catenin intracellular translocation and signaling. Biochim Biophys Acta (2011) 1.05
Thymosin beta 4 is dispensable for murine cardiac development and function. Circ Res (2011) 1.05
CD4 T cells promote CD8 T cell immunity at the priming and effector site during viral encephalitis. J Virol (2011) 1.03
Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells. Carcinogenesis (2012) 1.03
Differential requirements for IL-4/STAT6 signalling in CD4 T-cell fate determination and Th2-immune effector responses. Immunol Cell Biol (2009) 1.02
Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway. PLoS One (2010) 1.02
The antitumor activity of the fungicide ciclopirox. Int J Cancer (2010) 1.02
Suppression of allergic airway disease using mycobacterial lipoglycans. J Allergy Clin Immunol (2004) 1.01
IL-3 is required for increases in blood basophils in nematode infection in mice and can enhance IgE-dependent IL-4 production by basophils in vitro. Lab Invest (2008) 1.01
Cryptotanshinone inhibits cancer cell proliferation by suppressing Mammalian target of rapamycin-mediated cyclin D1 expression and Rb phosphorylation. Cancer Prev Res (Phila) (2010) 1.01
Bystander suppression of allergic airway inflammation by lung resident memory CD8+ T cells. Proc Natl Acad Sci U S A (2004) 1.00
Cryptotanshinone activates p38/JNK and inhibits Erk1/2 leading to caspase-independent cell death in tumor cells. Cancer Prev Res (Phila) (2012) 0.99
Percutaneous mechanical thrombectomy combined with catheter-directed thrombolysis in the treatment of symptomatic lower extremity deep venous thrombosis. Eur J Radiol (2008) 0.99
Cathode performance as a factor in electricity generation in microbial fuel cells. Environ Sci Technol (2004) 0.98
Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression. Neoplasia (2012) 0.98
Differential requirements of MHC and of DCs for endogenous proliferation of different T-cell subsets in vivo. Proc Natl Acad Sci U S A (2009) 0.97
Biohydrogen production from xylose at extreme thermophilic temperatures (70 degrees C) by mixed culture fermentation. Water Res (2008) 0.96
Evaluation of procedures to acclimate a microbial fuel cell for electricity production. Appl Microbiol Biotechnol (2005) 0.96
Jak3 negatively regulates dendritic-cell cytokine production and survival. Blood (2005) 0.96
A key role for lung-resident memory lymphocytes in protective immune responses after BCG vaccination. Eur J Immunol (2010) 0.95
Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine. Vaccine (2010) 0.95
Electricity generation and microbial community response to substrate changes in microbial fuel cell. Bioresour Technol (2010) 0.94
Basophils can directly present or cross-present antigen to CD8 lymphocytes and alter CD8 T cell differentiation into IL-10-producing phenotypes. J Immunol (2009) 0.94
Basophils: a potential liaison between innate and adaptive immunity. Allergol Int (2006) 0.94
Allergen-specific CTL require perforin expression to suppress allergic airway inflammation. J Immunol (2012) 0.93
Panax notogingseng saponins suppress RAGE/MAPK signaling and NF-kappaB activation in apolipoprotein-E-deficient atherosclerosis-prone mice. Cell Physiol Biochem (2012) 0.93
Biohydrogen production from wheat straw hydrolysate by dark fermentation using extreme thermophilic mixed culture. Biotechnol Bioeng (2010) 0.93
Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy. Hum Mol Genet (2011) 0.92
Comprehensive mutation analysis by whole-exome sequencing in 41 Chinese families with Leber congenital amaurosis. Invest Ophthalmol Vis Sci (2013) 0.91
Astragalus polysaccharides suppress ICAM-1 and VCAM-1 expression in TNF-α-treated human vascular endothelial cells by blocking NF-κB activation. Acta Pharmacol Sin (2013) 0.91
Association of TNF-alpha genetic polymorphisms with hepatocellular carcinoma susceptibility: a case-control study in a Han Chinese population. Int J Biol Markers (2011) 0.91
Effector lymphoid tissue and its crucial role in protective immunity. Trends Immunol (2005) 0.91
Involvement of histone deacetylation in MORC2-mediated down-regulation of carbonic anhydrase IX. Nucleic Acids Res (2010) 0.91
Repertoire-dependent immunopathology. J Autoimmun (2007) 0.90
Antibodies and IL-3 support helminth-induced basophil expansion. Proc Natl Acad Sci U S A (2012) 0.90
Magnetic field sensor using the fiber loop ring-down technique and an etched fiber coated with magnetic fluid. Appl Opt (2016) 0.90
Determination of the metals by ICP-MS in wild mushrooms from Yunnan, China. J Food Sci (2012) 0.89
IL-15 produced and trans-presented by DCs underlies homeostatic competition between CD8 and {gamma}{delta} T cells in vivo. Blood (2009) 0.88
Basophils, IgE, and autoantibody-mediated kidney disease. J Immunol (2011) 0.88
Cutting edge: IFN-γR signaling in non-T cell targets regulates T cell-mediated intestinal inflammation through multiple mechanisms. J Immunol (2014) 0.88
Both exogenous commensal and endogenous self antigens stimulate T cell proliferation under lymphopenic conditions. Cell Immunol (2011) 0.87
Basophils: in the spotlight at last. Nat Immunol (2008) 0.87
miR-200s contribute to interleukin-6 (IL-6)-induced insulin resistance in hepatocytes. J Biol Chem (2013) 0.87
Drug resistance and HCV coinfection in former blood donors infected with HIV type 1 in China. AIDS Res Hum Retroviruses (2011) 0.86
Immature murine NKT cells pass through a stage of developmentally programmed innate IL-4 secretion. J Leukoc Biol (2012) 0.86
Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo. Proc Natl Acad Sci U S A (2012) 0.85
Characterization of breast precancerous lesions and myoepithelial hyperplasia in sclerosing adenosis with apocrine metaplasia. Mol Oncol (2007) 0.84
Hypoglycemia and death in mice following experimental exposure to an extract of Trogia venenata mushrooms. PLoS One (2012) 0.84
A combined proteome and ultrastructural localization analysis of 14-3-3 proteins in transformed human amnion (AMA) cells: definition of a framework to study isoform-specific differences. Mol Cell Proteomics (2008) 0.84
Ikaros limits basophil development by suppressing C/EBP-α expression. Blood (2013) 0.83
Development of CD4 T Cell Dependent Immunity Against N. brasiliensis Infection. Front Immunol (2013) 0.83
Secretory products from infective forms of Nippostrongylus brasiliensis induce a rapid allergic airway inflammatory response. Immunol Cell Biol (2005) 0.83
Mycology, cultivation, traditional uses, phytochemistry and pharmacology of Wolfiporia cocos (Schwein.) Ryvarden et Gilb.: a review. J Ethnopharmacol (2013) 0.83
Blimp-1 induced by IL-4 plays a critical role in suppressing IL-2 production in activated CD4 T cells. J Immunol (2008) 0.83
In situ microbial fuel cell-based biosensor for organic carbon. Bioelectrochemistry (2011) 0.83
Recombinant human bone morphogenetic protein-2 versus autogenous iliac crest bone graft for lumbar fusion: a meta-analysis of ten randomized controlled trials. Arch Orthop Trauma Surg (2012) 0.82