Published in Nat Immunol on May 24, 2009
How are T(H)2-type immune responses initiated and amplified? Nat Rev Immunol (2010) 4.34
Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med (2010) 3.24
Effector T cell plasticity: flexibility in the face of changing circumstances. Nat Immunol (2010) 3.12
IgE, mast cells, basophils, and eosinophils. J Allergy Clin Immunol (2010) 3.04
Inflammatory dendritic cells--not basophils--are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen. J Exp Med (2010) 2.91
Intestinal bacteria and the regulation of immune cell homeostasis. Annu Rev Immunol (2010) 2.85
Dendritic cell subsets in primary and secondary T cell responses at body surfaces. Nat Immunol (2009) 2.76
The many paths to asthma: phenotype shaped by innate and adaptive immunity. Nat Immunol (2010) 2.74
Sensing the outside world: TSLP regulates barrier immunity. Nat Immunol (2010) 2.72
MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion. Immunity (2014) 2.55
Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation. Nat Med (2012) 2.49
Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. J Immunol (2009) 2.47
TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation. Nature (2011) 2.42
CD301b⁺ dermal dendritic cells drive T helper 2 cell-mediated immunity. Immunity (2013) 2.31
Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks. J Clin Invest (2010) 2.29
Programming dendritic cells to induce T(H)2 and tolerogenic responses. Nat Immunol (2010) 2.29
New paradigms in type 2 immunity. Science (2012) 2.27
CD11c depletion severely disrupts Th2 induction and development in vivo. J Exp Med (2010) 2.26
Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses. J Exp Med (2009) 2.24
Asthma and allergic inflammation. Cell (2010) 2.21
The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling. Nat Immunol (2010) 2.20
Innate cells and T helper 2 cell immunity in airway inflammation. Immunity (2009) 1.94
Mast cells and inflammation. Biochim Biophys Acta (2010) 1.91
Orchestrating house dust mite-associated allergy in the lung. Trends Immunol (2011) 1.86
The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses. Immunity (2012) 1.84
Genetic analysis of basophil function in vivo. Nat Immunol (2011) 1.82
Immunoglobulin responses at the mucosal interface. Annu Rev Immunol (2011) 1.82
Mechanical injury polarizes skin dendritic cells to elicit a T(H)2 response by inducing cutaneous thymic stromal lymphopoietin expression. J Allergy Clin Immunol (2010) 1.78
Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk. Nat Immunol (2011) 1.67
Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function. Proc Natl Acad Sci U S A (2009) 1.63
Indigenous enteric eosinophils control DCs to initiate a primary Th2 immune response in vivo. J Exp Med (2014) 1.59
Mouse neutrophils are professional antigen-presenting cells programmed to instruct Th1 and Th17 T-cell differentiation. Int Immunol (2011) 1.58
Type 2 cytokines: mechanisms and therapeutic strategies. Nat Rev Immunol (2015) 1.57
Basophils are not the key antigen-presenting cells in allergic patients. Allergy (2012) 1.57
CD4⁺T cells: differentiation and functions. Clin Dev Immunol (2012) 1.56
Protective and pathological roles of mast cells and basophils. Nat Rev Immunol (2013) 1.54
Pulmonary CD103(+) dendritic cells prime Th2 responses to inhaled allergens. Mucosal Immunol (2011) 1.32
Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses. J Immunol (2010) 1.32
Treatment of allergic asthma: modulation of Th2 cells and their responses. Respir Res (2011) 1.31
Basophils and allergic inflammation. J Allergy Clin Immunol (2013) 1.29
Insights into the initiation of type 2 immune responses. Immunology (2011) 1.25
Type 2 innate immune responses and the natural helper cell. Immunology (2011) 1.24
New insights into innate immune mechanisms underlying allergenicity. Mucosal Immunol (2009) 1.23
Chronic inflammation and asthma. Mutat Res (2009) 1.22
Eosinophils and Th2 immunity: contemporary insights. Immunol Cell Biol (2010) 1.22
Matrix metalloproteinase-2 conditions human dendritic cells to prime inflammatory T(H)2 cells via an IL-12- and OX40L-dependent pathway. Cancer Cell (2011) 1.22
Aging and immune function: molecular mechanisms to interventions. Antioxid Redox Signal (2011) 1.18
Similarity and diversity in macrophage activation by nematodes, trematodes, and cestodes. J Biomed Biotechnol (2010) 1.16
Healthy human T-Cell Responses to Aspergillus fumigatus antigens. PLoS One (2010) 1.14
Dynamic role of epithelium-derived cytokines in asthma. Clin Immunol (2012) 1.14
Basophils are the major producers of IL-4 during primary helminth infection. J Immunol (2011) 1.14
Mechanism of immunopotentiation and safety of aluminum adjuvants. Front Immunol (2013) 1.13
The biology of thymic stromal lymphopoietin (TSLP). Adv Pharmacol (2013) 1.12
Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A. Eur J Immunol (2010) 1.12
Cytokines of the γ(c) family control CD4+ T cell differentiation and function. Nat Immunol (2012) 1.12
The skin is an important bulwark of acquired immunity against intestinal helminths. J Exp Med (2013) 1.11
Innate immune cells in liver inflammation. Mediators Inflamm (2012) 1.11
Innate B cell helpers reveal novel types of antibody responses. Nat Immunol (2013) 1.11
Development, regulation and functional capacities of Th17 cells. Semin Immunopathol (2010) 1.10
Role of basophils in the initiation of Th2 responses. Curr Opin Immunol (2010) 1.10
Endolysosomal proteases and their inhibitors in immunity. Nat Rev Immunol (2009) 1.10
GM-CSF: An immune modulatory cytokine that can suppress autoimmunity. Cytokine (2015) 1.09
Formation of a mast cell synapse: Fc epsilon RI membrane dynamics upon binding mobile or immobilized ligands on surfaces. J Immunol (2009) 1.09
Evidence of pathway-specific basophil anergy induced by peanut oral immunotherapy in peanut-allergic children. Clin Exp Allergy (2012) 1.08
Selective and site-specific mobilization of dermal dendritic cells and Langerhans cells by Th1- and Th2-polarizing adjuvants. Proc Natl Acad Sci U S A (2010) 1.06
Basophils are required for the induction of Th2 immunity to haptens and peptide antigens. Nat Commun (2013) 1.05
Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines. Proc Natl Acad Sci U S A (2012) 1.05
Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation. Proc Natl Acad Sci U S A (2011) 1.05
Natural killer (NK)-dendritic cell interactions generate MHC class II-dressed NK cells that regulate CD4+ T cells. Proc Natl Acad Sci U S A (2011) 1.04
Directing dendritic cell immunotherapy towards successful cancer treatment. Immunotherapy (2010) 1.04
Trichuris muris: a model of gastrointestinal parasite infection. Semin Immunopathol (2012) 1.04
Lung dendritic cells at the innate-adaptive immune interface. J Leukoc Biol (2011) 1.03
Exposure to food allergens through inflamed skin promotes intestinal food allergy through the thymic stromal lymphopoietin-basophil axis. J Allergy Clin Immunol (2014) 1.03
Transcription factor networks in dendritic cell development. Semin Immunol (2011) 1.03
Cellular networks controlling Th2 polarization in allergy and immunity. F1000 Biol Rep (2012) 1.02
Functions of thymic stromal lymphopoietin in immunity and disease. Immunol Res (2012) 1.00
New insights into basophil biology: initiators, regulators, and effectors of type 2 inflammation. Ann N Y Acad Sci (2011) 1.00
Guilt by intimate association: what makes an allergen an allergen? J Allergy Clin Immunol (2010) 1.00
Thymic stromal lymphopoietin-dependent basophils promote Th2 cytokine responses following intestinal helminth infection. J Immunol (2012) 1.00
Dendritic cell-associated lectin 2 (DCAL2) defines a distinct CD8α- dendritic cell subset. J Leukoc Biol (2011) 0.99
The TNF-family cytokine TL1A promotes allergic immunopathology through group 2 innate lymphoid cells. Mucosal Immunol (2013) 0.99
Allergic sensitization: host-immune factors. Clin Transl Allergy (2014) 0.97
The role of toll-like receptors in acute and chronic lung inflammation. J Inflamm (Lond) (2010) 0.97
Type 2 innate immunity in helminth infection is induced redundantly and acts autonomously following CD11c(+) cell depletion. Infect Immun (2012) 0.97
Immunoglobulin E signal inhibition during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cells. Immunity (2014) 0.97
Thymic stromal lymphopoietin-mediated epicutaneous inflammation promotes acute diarrhea and anaphylaxis. J Clin Invest (2014) 0.96
Basophils trump dendritic cells as APCs for T(H)2 responses. Nat Immunol (2009) 0.96
Cellular immune response parameters that influence IgE sensitization. J Immunol Methods (2012) 0.94
Eosinophils and allergic airway disease: there is more to the story. Trends Immunol (2009) 0.94
Murine B cells regulate serum IgE levels in a CD23-dependent manner. J Immunol (2010) 0.93
Eosinophils contribute to IL-4 production and shape the T-helper cytokine profile and inflammatory response in pulmonary cryptococcosis. Am J Pathol (2011) 0.93
Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity. J Exp Med (2010) 0.92
Innate immune responses in house dust mite allergy. ISRN Allergy (2013) 0.92
Functional heterogeneity in the basophil cell lineage. Adv Immunol (2012) 0.92
Human basophils express amphiregulin in response to T cell-derived IL-3. J Allergy Clin Immunol (2010) 0.92
T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production. Cytokine (2015) 0.92
Circulating human basophils lack the features of professional antigen presenting cells. Sci Rep (2013) 0.92
Regulation of human mast cell and basophil function by anaphylatoxins C3a and C5a. Immunol Lett (2009) 0.91
Chronic schistosome infection leads to modulation of granuloma formation and systemic immune suppression. Front Immunol (2013) 0.91
Innate immune recognition. Annu Rev Immunol (2001) 26.65
Toll-like receptor control of the adaptive immune responses. Nat Immunol (2004) 19.15
The immunological synapse: a molecular machine controlling T cell activation. Science (1999) 17.41
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol (2008) 16.65
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens. Immunity (2002) 14.57
Three-dimensional segregation of supramolecular activation clusters in T cells. Nature (1998) 14.14
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat Immunol (2007) 12.72
Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants. Nature (2008) 9.16
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat Immunol (2007) 8.92
Toll-like receptors control activation of adaptive immune responses. Nat Immunol (2001) 7.54
CD4 T cells: fates, functions, and faults. Blood (2008) 7.03
A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat Immunol (2008) 6.78
Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med (2002) 6.48
Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature (2007) 5.82
Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity. Immunity (2003) 5.52
Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter. Immunity (2001) 5.46
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature (2008) 4.85
Dectin-1: a signalling non-TLR pattern-recognition receptor. Nat Rev Immunol (2006) 4.84
Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production. Immunity (2004) 4.81
Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell (1993) 4.80
The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity. Eur J Immunol (2008) 4.72
The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph node. Immunity (2005) 4.72
Cutting edge: inflammasome activation by alum and alum's adjuvant effect are mediated by NLRP3. J Immunol (2008) 4.60
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J Exp Med (2004) 4.45
Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function. Nat Immunol (2005) 4.22
Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system. J Exp Med (2006) 4.11
Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation. Blood (1998) 3.98
Basophils enhance immunological memory responses. Nat Immunol (2008) 3.35
Dendritic cells maximize the memory CD8 T cell response to infection. Immunity (2005) 3.21
Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release. J Immunol (2007) 3.17
Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis. Immunity (2008) 3.11
Induction of human IgE synthesis in B cells by mast cells and basophils. Nature (1993) 2.97
Inflammatory signals in dendritic cell activation and the induction of adaptive immunity. Immunol Rev (2009) 2.89
Regulation of MHC class II gene expression by the class II transactivator. Nat Rev Immunol (2005) 2.44
CD8- dendritic cell activation status plays an integral role in influencing Th2 response development. J Immunol (2001) 2.42
Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes. J Exp Med (1994) 2.42
Proteases in parasitic diseases. Annu Rev Pathol (2006) 2.26
MyD88-dependent induction of allergic Th2 responses to intranasal antigen. J Clin Invest (2005) 2.20
Class II transactivator regulates the expression of multiple genes involved in antigen presentation. J Exp Med (1995) 1.77
Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils. Blood (2007) 1.61
Newly discovered roles for basophils: a neglected minority gains new respect. Nat Rev Immunol (2009) 1.56
MHC class II expression restricted to CD8alpha+ and CD11b+ dendritic cells is sufficient for control of Leishmania major. J Exp Med (2004) 1.40
Basophils: a nonredundant contributor to host immunity. Immunity (2009) 1.38
CD8alpha+ and CD11b+ dendritic cell-restricted MHC class II controls Th1 CD4+ T cell immunity. J Immunol (2003) 1.37
Basophils: what they 'can do' versus what they 'actually do'. Nat Immunol (2008) 1.33
The cysteine protease activity of the major dust mite allergen Der p 1 selectively enhances the immunoglobulin E antibody response. J Exp Med (1999) 1.29
Identification of antigen-capturing cells as basophils. J Immunol (2005) 1.21
Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance. Blood (2005) 1.18
Cultured basophils but not cultured mast cells induce human IgE synthesis in B cells after immunologic stimulation. Clin Exp Immunol (1998) 1.09
Enzymatically active papain preferentially induces an allergic response in mice. Biochem Biophys Res Commun (1998) 1.01
Indirect involvement of allergen-captured mast cells in antigen presentation. Blood (2007) 1.00
Pattern recognition molecules and innate immunity to parasites. Trends Parasitol (2003) 0.98
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell (2004) 29.32
Innate immune recognition. Annu Rev Immunol (2001) 26.65
Toll-like receptor control of the adaptive immune responses. Nat Immunol (2004) 19.15
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science (2003) 14.04
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response. Immunity (2006) 10.61
Trex1 prevents cell-intrinsic initiation of autoimmunity. Cell (2008) 9.59
Regulation of lung injury and repair by Toll-like receptors and hyaluronan. Nat Med (2005) 8.49
Regulation of adaptive immunity by the innate immune system. Science (2010) 8.00
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat Immunol (2008) 7.87
Gene-specific control of inflammation by TLR-induced chromatin modifications. Nature (2007) 7.34
Type I interferons in host defense. Immunity (2006) 7.32
Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. J Exp Med (2003) 7.26
IRAK-M is a negative regulator of Toll-like receptor signaling. Cell (2002) 6.79
Regulation of phagosome maturation by signals from toll-like receptors. Science (2004) 6.79
A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat Immunol (2008) 6.78
Control of inducible gene expression by signal-dependent transcriptional elongation. Cell (2009) 6.57
Control of B-cell responses by Toll-like receptors. Nature (2005) 6.44
Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell (2006) 6.01
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature (2002) 5.95
Toll-like receptor signaling pathways. Science (2003) 5.86
Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science (2007) 5.54
Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature (2006) 5.54
Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol (2005) 4.30
Toll-like receptors and cancer. Nat Rev Cancer (2008) 4.29
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity. Nat Immunol (2009) 4.28
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature (2002) 4.15
Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity (2006) 3.98
Pattern recognition receptors and control of adaptive immunity. Immunol Rev (2009) 3.91
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. Cell Metab (2009) 3.64
Recognition of microbial infection by Toll-like receptors. Curr Opin Immunol (2003) 3.18
Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. J Immunol (2002) 3.12
On regulation of phagosome maturation and antigen presentation. Nat Immunol (2006) 3.11
Interactions between the host innate immune system and microbes in inflammatory bowel disease. Gastroenterology (2011) 2.90
Toll-dependent control mechanisms of CD4 T cell activation. Immunity (2004) 2.88
Toll-like receptors: linking innate and adaptive immunity. Adv Exp Med Biol (2005) 2.85
A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system. Cell Host Microbe (2010) 2.84
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. Nat Med (2002) 2.77
p53-mediated hematopoietic stem and progenitor cell competition. Cell Stem Cell (2010) 2.65
Retroviral delivery of small interfering RNA into primary cells. Proc Natl Acad Sci U S A (2002) 2.43
Toll-like receptors: linking innate and adaptive immunity. Microbes Infect (2004) 2.38
Cutting edge: TLR4 deficiency confers susceptibility to lethal oxidant lung injury. J Immunol (2005) 2.30
Role of tissue protection in lethal respiratory viral-bacterial coinfection. Science (2013) 2.22
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition. Proc Natl Acad Sci U S A (2014) 2.22
Age-associated defect in human TLR-1/2 function. J Immunol (2007) 2.20
Th22 and related cytokines in inflammatory and autoimmune diseases. Expert Opin Ther Targets (2012) 2.14
NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway. Nat Immunol (2007) 2.11
Regulation of pulmonary fibrosis by chemokine receptor CXCR3. J Clin Invest (2004) 2.10
Triggering TLR signaling in vaccination. Trends Immunol (2005) 2.09
Allergic host defences. Nature (2012) 1.99
Migratory and lymphoid-resident dendritic cells cooperate to efficiently prime naive CD4 T cells. Immunity (2008) 1.95
Control of adaptive immune responses by Toll-like receptors. Curr Opin Immunol (2002) 1.92
The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cells. Immunity (2002) 1.89
Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. Immunity (2013) 1.88
Bee venom phospholipase A2 induces a primary type 2 response that is dependent on the receptor ST2 and confers protective immunity. Immunity (2013) 1.88
Dendritic cells and B cells maximize mucosal Th1 memory response to herpes simplex virus. J Exp Med (2008) 1.86
Cutting edge: dendritic cell-restricted antigen presentation initiates the follicular helper T cell program but cannot complete ultimate effector differentiation. J Immunol (2011) 1.84
Behavior of parasite-specific effector CD8+ T cells in the brain and visualization of a kinesis-associated system of reticular fibers. Immunity (2009) 1.84
Gene-specific control of the TLR-induced inflammatory response. Clin Immunol (2008) 1.80
Toll-like receptors and acquired immunity. Semin Immunol (2004) 1.79
Human brucellosis in the People's Republic of China during 2005-2010. Int J Infect Dis (2013) 1.71
Innate control of adaptive immunity via remodeling of lymph node feed arteriole. Proc Natl Acad Sci U S A (2005) 1.62
Innate immunity--cross-talk with adaptive immunity through pattern recognition receptors and cytokines. Curr Opin Immunol (2006) 1.62
Adaptor protein-3 in dendritic cells facilitates phagosomal toll-like receptor signaling and antigen presentation to CD4(+) T cells. Immunity (2012) 1.59
Host defense pathways: role of redundancy and compensation in infectious disease phenotypes. Immunity (2011) 1.57
Prevaccine determination of the expression of costimulatory B7 molecules in activated monocytes predicts influenza vaccine responses in young and older adults. J Infect Dis (2007) 1.56
Targeting of immune signalling networks by bacterial pathogens. Nat Cell Biol (2009) 1.52
The control of adaptive immune responses by the innate immune system. Adv Immunol (2011) 1.48
Influenza virus-induced glucocorticoids compromise innate host defense against a secondary bacterial infection. Cell Host Microbe (2010) 1.47
Plasmacytoid dendritic cells are activated by Toxoplasma gondii to present antigen and produce cytokines. J Immunol (2008) 1.45
TLR4 up-regulation at protein or gene level is pathogenic for lupus-like autoimmune disease. J Immunol (2006) 1.44
MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice. Nat Commun (2012) 1.44
ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein. FASEB J (2006) 1.43
CD4+ CD25+ regulatory T cells inhibit the maturation but not the initiation of an autoantibody response. J Immunol (2005) 1.42
MHC class II expression restricted to CD8alpha+ and CD11b+ dendritic cells is sufficient for control of Leishmania major. J Exp Med (2004) 1.40
Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus. Immunity (2013) 1.40
Antiviral defense: interferons and beyond. J Exp Med (2006) 1.38
Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4. J Clin Invest (2010) 1.38
Elevated Th22 cells correlated with Th17 cells in patients with rheumatoid arthritis. J Clin Immunol (2011) 1.38
CD8alpha+ and CD11b+ dendritic cell-restricted MHC class II controls Th1 CD4+ T cell immunity. J Immunol (2003) 1.37
Integration of cytokine and heterologous receptor signaling pathways. Nat Immunol (2009) 1.36
Control of infection by pyroptosis and autophagy: role of TLR and NLR. Cell Mol Life Sci (2010) 1.35
Toll-like receptors: balancing host resistance with immune tolerance. Curr Opin Immunol (2003) 1.34
Semaphorin 7A is a negative regulator of T cell responses. Immunity (2006) 1.33
Adjuvants of immunity: harnessing innate immunity to promote adaptive immunity. J Exp Med (2002) 1.33
CD44 is a negative regulator of acute pulmonary inflammation and lipopolysaccharide-TLR signaling in mouse macrophages. J Immunol (2007) 1.32
Abnormal trafficking and degradation of TLR4 underlie the elevated inflammatory response in cystic fibrosis. J Immunol (2011) 1.31
ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein. J Biol Chem (2006) 1.27
Reduced secretion of YopJ by Yersinia limits in vivo cell death but enhances bacterial virulence. PLoS Pathog (2008) 1.27
Evolution of inflammatory diseases. Curr Biol (2012) 1.27
Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis. J Biol Chem (2004) 1.24
Impact of CD1d deficiency on metabolism. PLoS One (2011) 1.21
Learning tolerance while fighting ignorance. Cell (2009) 1.20
Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance. Proc Natl Acad Sci U S A (2008) 1.20
A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages. PLoS Pathog (2011) 1.14