Published in J Cell Biol on December 04, 2006
SUMO: a multifaceted modifier of chromatin structure and function. Dev Cell (2013) 1.50
Human Wrnip1 is localized in replication factories in a ubiquitin-binding zinc finger-dependent manner. J Biol Chem (2008) 1.37
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair. Proc Natl Acad Sci U S A (2013) 1.21
Expression and function of a large non-coding RNA gene XIST in human cancer. World J Surg (2011) 1.15
Heterochromatin instability in cancer: from the Barr body to satellites and the nuclear periphery. Semin Cancer Biol (2012) 1.01
XIST RNA and architecture of the inactive X chromosome: implications for the repeat genome. Cold Spring Harb Symp Quant Biol (2011) 0.94
A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function. Nucleic Acids Res (2014) 0.91
Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions. J Biol Chem (2014) 0.85
Replication stress in Mammalian cells and its consequences for mitosis. Genes (Basel) (2015) 0.85
PI 3 kinase related kinases-independent proteolysis of BRCA1 regulates Rad51 recruitment during genotoxic stress in human cells. PLoS One (2010) 0.84
Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice. BMC Mol Biol (2010) 0.79
Bi-phasic expression of Heterochromatin Protein 1 (HP1) during breast cancer progression: Potential roles of HP1 and chromatin structure in tumorigenesis. J Nat Sci (2015) 0.77
Dysregulation of long non-coding RNA in breast cancer: an overview of mechanism and clinical implication. Oncotarget (2016) 0.75
Centromeres and kinetochores: from epigenetics to mitotic checkpoint signaling. Cell (2003) 9.90
Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell (1997) 8.28
X chromosomal abnormalities in basal-like human breast cancer. Cancer Cell (2006) 7.17
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell (1997) 5.92
XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure. J Cell Biol (1996) 5.51
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell (2001) 5.05
Genomic and genetic definition of a functional human centromere. Science (2001) 4.28
A shift from reversible to irreversible X inactivation is triggered during ES cell differentiation. Mol Cell (2000) 4.26
The dynamic kinetochore-microtubule interface. J Cell Sci (2004) 4.07
Mapping replicational sites in the eucaryotic cell nucleus. J Cell Biol (1989) 3.89
Mouse centric and pericentric satellite repeats form distinct functional heterochromatin. J Cell Biol (2004) 3.65
BRCA1 and BRCA2 and the genetics of breast and ovarian cancer. Hum Mol Genet (2001) 2.98
Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation. J Cell Biol (2001) 2.94
Senescence, aging, and malignant transformation mediated by p53 in mice lacking the Brca1 full-length isoform. Genes Dev (2003) 2.78
BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation. Curr Biol (2004) 2.67
BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number. Mol Cell Biol (2004) 2.46
Clustering of multiple specific genes and gene-rich R-bands around SC-35 domains: evidence for local euchromatic neighborhoods. J Cell Biol (2003) 2.38
BRCA1 supports XIST RNA concentration on the inactive X chromosome. Cell (2002) 2.24
Rad51 accumulation at sites of DNA damage and in postreplicative chromatin. J Cell Biol (2000) 2.22
An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells. Proc Natl Acad Sci U S A (2002) 2.03
Synthesis of the nuclear protein cyclin (PCNA) and its relationship with DNA replication. Exp Cell Res (1986) 1.92
A CAF-1 dependent pool of HP1 during heterochromatin duplication. EMBO J (2004) 1.88
The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair. Curr Opin Cell Biol (2003) 1.65
BRCA1 participates in DNA decatenation. Nat Struct Mol Biol (2005) 1.59
Roles of BRCA1 in DNA damage repair: a link between development and cancer. Hum Mol Genet (2003) 1.54
Human CENP-H multimers colocalize with CENP-A and CENP-C at active centromere--kinetochore complexes. Hum Mol Genet (2000) 1.50
The 4q subtelomere harboring the FSHD locus is specifically anchored with peripheral heterochromatin unlike most human telomeres. J Cell Biol (2004) 1.48
Integrated kinetics of X chromosome inactivation in differentiating embryonic stem cells. Cytogenet Genome Res (2002) 1.42
Loss of the inactive X chromosome and replication of the active X in BRCA1-defective and wild-type breast cancer cells. Cancer Res (2005) 1.25
Ubiquitinated proteins including uH2A on the human and mouse inactive X chromosome: enrichment in gene rich bands. Chromosoma (2004) 1.20
Human topoisomerase IIalpha: targeting to subchromosomal sites of activity during interphase and mitosis. Mol Biol Cell (2004) 1.02
BRCA1 does not paint the inactive X to localize XIST RNA but may contribute to broad changes in cancer that impact XIST and Xi heterochromatin. J Cell Biochem (2007) 0.97
BRCA1 associates with the inactive X chromosome in late S-phase, coupled with transient H2AX phosphorylation. Chromosoma (2005) 0.92
A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains. BMC Genomics (2007) 6.28
An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol Cell (2009) 6.08
The three-dimensional folding of the α-globin gene domain reveals formation of chromatin globules. Nat Struct Mol Biol (2010) 3.39
A long noncoding RNA mediates both activation and repression of immune response genes. Science (2013) 2.85
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells. J Cell Biol (2008) 2.39
Clustering of multiple specific genes and gene-rich R-bands around SC-35 domains: evidence for local euchromatic neighborhoods. J Cell Biol (2003) 2.38
Molecular anatomy of a speckle. Anat Rec A Discov Mol Cell Evol Biol (2006) 2.37
An ectopic human XIST gene can induce chromosome inactivation in postdifferentiation human HT-1080 cells. Proc Natl Acad Sci U S A (2002) 2.03
Translating dosage compensation to trisomy 21. Nature (2013) 1.75
Maternal Rnf12/RLIM is required for imprinted X-chromosome inactivation in mice. Nature (2010) 1.64
X-inactivation reveals epigenetic anomalies in most hESC but identifies sublines that initiate as expected. J Cell Physiol (2008) 1.59
The 4q subtelomere harboring the FSHD locus is specifically anchored with peripheral heterochromatin unlike most human telomeres. J Cell Biol (2004) 1.48
The disappearing Barr body in breast and ovarian cancers. Nat Rev Cancer (2007) 1.24
Word frequency analysis reveals enrichment of dinucleotide repeats on the human X chromosome and [GATA]n in the X escape region. Genome Res (2006) 1.20
Ubiquitinated proteins including uH2A on the human and mouse inactive X chromosome: enrichment in gene rich bands. Chromosoma (2004) 1.20
Defining early steps in mRNA transport: mutant mRNA in myotonic dystrophy type I is blocked at entry into SC-35 domains. J Cell Biol (2007) 1.16
Characterization of expression at the human XIST locus in somatic, embryonal carcinoma, and transgenic cell lines. Genomics (2003) 1.14
Higher-order unfolding of satellite heterochromatin is a consistent and early event in cell senescence. J Cell Biol (2013) 1.13
Aberrant silencing of cancer-related genes by CpG hypermethylation occurs independently of their spatial organization in the nucleus. Cancer Res (2010) 1.10
Inducible XIST-dependent X-chromosome inactivation in human somatic cells is reversible. Proc Natl Acad Sci U S A (2007) 1.09
Unbalanced X;autosome translocations provide evidence for sequence specificity in the association of XIST RNA with chromatin. Hum Mol Genet (2002) 1.08
Evidence that all SC-35 domains contain mRNAs and that transcripts can be structurally constrained within these domains. J Struct Biol (2002) 1.08
The cell biology of a novel chromosomal RNA: chromosome painting by XIST/Xist RNA initiates a remodeling cascade. Semin Cell Dev Biol (2003) 1.03
Heterochromatin instability in cancer: from the Barr body to satellites and the nuclear periphery. Semin Cancer Biol (2012) 1.01
Changing nuclear landscape and unique PML structures during early epigenetic transitions of human embryonic stem cells. J Cell Biochem (2009) 0.99
BRCA1 does not paint the inactive X to localize XIST RNA but may contribute to broad changes in cancer that impact XIST and Xi heterochromatin. J Cell Biochem (2007) 0.97
Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells. Cell (2012) 0.97
Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton. J Cell Sci (2003) 0.97
AURKB-mediated effects on chromatin regulate binding versus release of XIST RNA to the inactive chromosome. J Cell Biol (2009) 0.94
c-Myc localization within the nucleus: evidence for association with the PML nuclear body. J Cell Biochem (2004) 0.89
A multifaceted FISH approach to study endogenous RNAs and DNAs in native nuclear and cell structures. Curr Protoc Hum Genet (2013) 0.85
Unfolding the story of chromatin organization in senescent cells. Nucleus (2015) 0.75