| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
PEGylated nanoparticles for biological and pharmaceutical applications.
|
Adv Drug Deliv Rev
|
2003
|
3.19
|
|
2
|
Lactosylated poly(ethylene glycol)-siRNA conjugate through acid-labile beta-thiopropionate linkage to construct pH-sensitive polyion complex micelles achieving enhanced gene silencing in hepatoma cells.
|
J Am Chem Soc
|
2005
|
1.66
|
|
3
|
pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector.
|
Bioconjug Chem
|
2006
|
1.24
|
|
4
|
Two-dimensional multiarray formation of hepatocyte spheroids on a microfabricated PEG-brush surface.
|
Chembiochem
|
2004
|
1.12
|
|
5
|
Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid.
|
Biomaterials
|
2011
|
1.09
|
|
6
|
A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo.
|
J Control Release
|
2009
|
1.06
|
|
7
|
A core-shell-type fluorescent nanosphere possessing reactive poly(ethylene glycol) tethered chains on the surface for zeptomole detection of protein in time-resolved fluorometric immunoassay.
|
Anal Chem
|
2003
|
1.04
|
|
8
|
Smart siRNA delivery systems based on polymeric nanoassemblies and nanoparticles.
|
Nanomedicine (Lond)
|
2010
|
1.01
|
|
9
|
A reactive poly(ethylene glycol) layer to achieve specific surface plasmon resonance sensing with a high S/N ratio: the substantial role of a short underbrushed PEG layer in minimizing nonspecific adsorption.
|
Anal Chem
|
2005
|
1.00
|
|
10
|
Preparation of a novel PEG-clay hybrid as a DDS material: dispersion stability and sustained release profiles.
|
J Control Release
|
2005
|
0.99
|
|
11
|
Design of poly(ethylene glycol)/streptavidin coimmobilized upconversion nanophosphors and their application to fluorescence biolabeling.
|
Langmuir
|
2008
|
0.97
|
|
12
|
An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice.
|
Gastroenterology
|
2012
|
0.95
|
|
13
|
Nanospheres for DNA separation chips.
|
Nat Biotechnol
|
2004
|
0.95
|
|
14
|
Enhanced growth inhibition of hepatic multicellular tumor spheroids by lactosylated poly(ethylene glycol)-siRNA conjugate formulated in PEGylated polyplexes.
|
ChemMedChem
|
2007
|
0.94
|
|
15
|
Lactose-installed poly(ethylene glycol)-poly(d,l-lactide) block copolymer micelles exhibit fast-rate binding and high affinity toward a protein bed simulating a cell surface. A surface plasmon resonance study.
|
Bioconjug Chem
|
2003
|
0.93
|
|
16
|
Direct observation of adsorption-induced inactivation of antibody fragments surrounded by mixed-PEG layer on a gold surface.
|
J Am Chem Soc
|
2010
|
0.93
|
|
17
|
Ligand density effect on biorecognition by PEGylated gold nanoparticles: regulated interaction of RCA120 lectin with lactose installed to the distal end of tethered PEG strands on gold surface.
|
Biomacromolecules
|
2005
|
0.93
|
|
18
|
Intracellular inducible alkylation system that exhibits antisense effects with greater potency and selectivity than the natural oligonucleotide.
|
Angew Chem Int Ed Engl
|
2006
|
0.93
|
|
19
|
Temperature-related change in the properties relevant to drug delivery of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles in aqueous milieu.
|
J Control Release
|
2002
|
0.92
|
|
20
|
Density control of poly(ethylene glycol) layer to regulate cellular attachment.
|
Langmuir
|
2007
|
0.91
|
|
21
|
pH-sensitive radical-containing-nanoparticle (RNP) for the L-band-EPR imaging of low pH circumstances.
|
Bioconjug Chem
|
2009
|
0.91
|
|
22
|
On-off regulation of 19F magnetic resonance signals based on pH-sensitive PEGylated nanogels for potential tumor-specific smart 19F MRI probes.
|
Bioconjug Chem
|
2007
|
0.89
|
|
23
|
pH-responsive oligodeoxynucleotide (ODN)-poly(ethylene glycol) conjugate through acid-labile beta-thiopropionate linkage: preparation and polyion complex micelle formation.
|
Biomacromolecules
|
2003
|
0.89
|
|
24
|
Enhanced cytoplasmic delivery of siRNA using a stabilized polyion complex based on PEGylated nanogels with a cross-linked polyamine structure.
|
Biomacromolecules
|
2009
|
0.89
|
|
25
|
Redox nanoparticle treatment protects against neurological deficit in focused ultrasound-induced intracerebral hemorrhage.
|
Nanomedicine (Lond)
|
2012
|
0.88
|
|
26
|
Newly synthesized radical-containing nanoparticles enhance neuroprotection after cerebral ischemia-reperfusion injury.
|
Neurosurgery
|
2011
|
0.88
|
|
27
|
Inverted pattern formation of cell microarrays on poly(ethylene glycol) (PEG) gel patterned surface and construction of hepatocyte spheroids on unmodified PEG gel microdomains.
|
Lab Chip
|
2009
|
0.87
|
|
28
|
Smart polymeric micelles as nanocarriers for oligonucleotides and siRNA delivery.
|
Nucleic Acids Symp Ser (Oxf)
|
2005
|
0.87
|
|
29
|
Supramolecular assemblies for the cytoplasmic delivery of antisense oligodeoxynucleotide: polyion complex (PIC) micelles based on poly(ethylene glycol)-SS-oligodeoxynucleotide conjugate.
|
Biomacromolecules
|
2005
|
0.87
|
|
30
|
Polyion complex micelles of pDNA with acetal-poly(ethylene glycol)-poly(2-(dimethylamino)ethyl methacrylate) block copolymer as the gene carrier system: physicochemical properties of micelles relevant to gene transfection efficacy.
|
Biomacromolecules
|
2004
|
0.85
|
|
31
|
The ROS scavenging and renal protective effects of pH-responsive nitroxide radical-containing nanoparticles.
|
Biomaterials
|
2011
|
0.85
|
|
32
|
Smart polyion complex micelles for targeted intracellular delivery of PEGylated antisense oligonucleotides containing acid-labile linkages.
|
Chembiochem
|
2005
|
0.84
|
|
33
|
Design of core--shell-type nanoparticles carrying stable radicals in the core.
|
Biomacromolecules
|
2009
|
0.84
|
|
34
|
Efficient short interference RNA delivery to tumor cells using a combination of octaarginine, GALA and tumor-specific, cleavable polyethylene glycol system.
|
Biol Pharm Bull
|
2009
|
0.84
|
|
35
|
Block ionomer complexes of PEG-block-poly(4-vinylbenzylphosphonate) and cationic surfactants as highly stable, pH responsive drug delivery system.
|
J Control Release
|
2012
|
0.84
|
|
36
|
Thermal characterization of poly(ethylene glycol)-poly(D,L-lactide) block copolymer micelles based on pyrene excimer formation.
|
J Control Release
|
2004
|
0.83
|
|
37
|
Suppression of NSAID-induced small intestinal inflammation by orally administered redox nanoparticles.
|
Biomaterials
|
2013
|
0.83
|
|
38
|
A high-performance waveguide-mode biosensor for detection of factor IX using PEG-based blocking agents to suppress non-specific binding and improve sensitivity.
|
Analyst
|
2013
|
0.83
|
|
39
|
Near-infrared (1550 nm) in vivo bioimaging based on rare-earth doped ceramic nanophosphors modified with PEG-b-poly(4-vinylbenzylphosphonate).
|
Nanoscale
|
2011
|
0.82
|
|
40
|
In vitro and in vivo characteristics of core-shell type nanogel particles: optimization of core cross-linking density and surface poly(ethylene glycol) density in PEGylated nanogels.
|
Acta Biomater
|
2011
|
0.82
|
|
41
|
Completely dispersible PEGylated gold nanoparticles under physiological conditions: modification of gold nanoparticles with precisely controlled PEG-b-polyamine.
|
Langmuir
|
2008
|
0.81
|
|
42
|
Creation of a mixed poly(ethylene glycol) tethered-chain surface for preventing the nonspecific adsorption of proteins and peptides.
|
Biointerphases
|
2007
|
0.81
|
|
43
|
Nitroxyl radical-containing nanoparticles for novel nanomedicine against oxidative stress injury.
|
Nanomedicine (Lond)
|
2011
|
0.81
|
|
44
|
Preparation of functionally Pegylated gold nanoparticles with narrow distribution through autoreduction of auric cation by alpha-biotinyl-PEG-block-[poly(2- (N,N-dimethylamino)ethyl methacrylate)].
|
Langmuir
|
2004
|
0.81
|
|
45
|
Glycolytic enzymes PGK1 and PKM2 as novel transcriptional targets of PPARγ in breast cancer pathophysiology.
|
J Drug Target
|
2012
|
0.81
|
|
46
|
Spheroid array of fetal mouse liver cells constructed on a PEG-gel micropatterned surface: upregulation of hepatic functions by co-culture with nonparenchymal liver cells.
|
Lab Chip
|
2009
|
0.81
|
|
47
|
Lactose-conjugated polyion complex micelles incorporating plasmid DNA as a targetable gene vector system: their preparation and gene transfecting efficiency against cultured HepG2 cells.
|
J Control Release
|
2004
|
0.81
|
|
48
|
Characterization of aldehyde-PEG tethered surfaces: influence of PEG chain length on the specific biorecognition.
|
Langmuir
|
2004
|
0.80
|
|
49
|
Studies on the adsorption property and structure of polyamine-ended poly(ethylene glycol) derivatives on a gold surface by surface plasmon resonance and angle-resolved X-ray photoelectron spectroscopy.
|
Langmuir
|
2009
|
0.80
|
|
50
|
Chemical nanotherapy: nitroxyl radical-containing nanoparticle protects neuroblastoma SH-SY5Y cells from Abeta-induced oxidative stress.
|
Ther Deliv
|
2011
|
0.80
|
|
51
|
Co-immobilized poly(ethylene glycol)-block-polyamines promote sensitivity and restrict biofouling on gold sensor surface for detecting factor IX in human plasma.
|
Analyst
|
2014
|
0.80
|
|
52
|
Different mechanisms of action of poly(ethylene glycol) and arginine on thermal inactivation of lysozyme and ribonuclease A.
|
Biotechnol Bioeng
|
2012
|
0.80
|
|
53
|
Efficient siRNA delivery based on PEGylated and partially quaternized polyamine nanogels: enhanced gene silencing activity by the cooperative effect of tertiary and quaternary amino groups in the core.
|
J Control Release
|
2010
|
0.80
|
|
54
|
The use of nitroxide radical-containing nanoparticles coupled with piperine to protect neuroblastoma SH-SY5Y cells from Aβ-induced oxidative stress.
|
Biomaterials
|
2011
|
0.80
|
|
55
|
Creation of a blood-compatible surface: a novel strategy for suppressing blood activation and coagulation using a nitroxide radical-containing polymer with reactive oxygen species scavenging activity.
|
Acta Biomater
|
2011
|
0.79
|
|
56
|
Non-Fouling Character of Poly[2-(methacryloyloxy)ethyl Phosphorylcholine]-Modified Gold Surfaces Fabricated by the 'Grafting to' Method: Comparison of its Protein Resistance with Poly(ethylene glycol)-Modified Gold Surfaces.
|
Macromol Rapid Commun
|
2009
|
0.79
|
|
57
|
Preparation of highly dispersible and tumor-accumulative, iron oxide nanoparticles Multi-point anchoring of PEG-b-poly(4-vinylbenzylphosphonate) improves performance significantly.
|
Colloids Surf B Biointerfaces
|
2011
|
0.79
|
|
58
|
Structure and activity assay of nanozymes prepared by the coimmobilization of practically useful enzymes and hydrophilic block copolymers on gold nanoparticles.
|
Langmuir
|
2008
|
0.79
|
|
59
|
Reactive oxygen species-scavenging nanomedicines for the treatment of oxidative stress injuries.
|
Adv Healthc Mater
|
2014
|
0.79
|
|
60
|
Development of silica-containing redox nanoparticles for medical applications.
|
Biomater Sci
|
2015
|
0.79
|
|
61
|
Synthesis of heterotelechelic poly(ethylene glycol) derivatives having alpha-benzaldehyde and omega-pyridyl disulfide groups by ring opening polymerization of ethylene oxide using 4-(diethoxymethyl)benzyl alkoxide as a novel initiator.
|
Bioconjug Chem
|
2004
|
0.78
|
|
62
|
Facile construction of sulfanyl-terminated poly(ethylene glycol)-brushed layer on a gold surface for protein immobilization by the combined use of sulfanyl-ended telechelic and semitelechelic poly(ethylene glycol)s.
|
Langmuir
|
2008
|
0.78
|
|
63
|
High-performance immunolatex possessing a mixed-PEG/antibody coimmobilized surface: highly sensitive ferritin immunodiagnostics.
|
Anal Chem
|
2009
|
0.78
|
|
64
|
Large payloads of gold nanoparticles into the polyamine network core of stimuli-responsive PEGylated nanogels for selective and noninvasive cancer photothermal therapy.
|
Nanoscale
|
2010
|
0.78
|
|
65
|
Electric stimulus opens intercellular spaces in skin.
|
J Biol Chem
|
2013
|
0.78
|
|
66
|
Tumor growth suppression by gadolinium-neutron capture therapy using gadolinium-entrapped liposome as gadolinium delivery agent.
|
Biomed Pharmacother
|
2012
|
0.77
|
|
67
|
Long-term survival and functional maintenance of hepatocytes by using a microfabricated cell array.
|
Colloids Surf B Biointerfaces
|
2012
|
0.77
|
|
68
|
Pharmacokinetics of core-polymerized, boron-conjugated micelles designed for boron neutron capture therapy for cancer.
|
Biomaterials
|
2012
|
0.77
|
|
69
|
Redox nanoparticle therapeutics to cancer--increase in therapeutic effect of doxorubicin, suppressing its adverse effect.
|
J Control Release
|
2013
|
0.77
|
|
70
|
High-performance surface acoustic wave immunosensing system on a PEG/aptamer hybridized surface.
|
Langmuir
|
2013
|
0.77
|
|
71
|
Coffee component hydroxyl hydroquinone (HHQ) as a putative ligand for PPAR gamma and implications in breast cancer.
|
BMC Genomics
|
2013
|
0.77
|
|
72
|
Redox-active injectable gel using thermo-responsive nanoscale polyion complex flower micelle for noninvasive treatment of local inflammation.
|
J Control Release
|
2013
|
0.77
|
|
73
|
Regulation of lysozyme activity based on thermotolerant protein/smart polymer complex formation.
|
J Am Chem Soc
|
2009
|
0.76
|
|
74
|
High PEGylation efficiency of pentaethylenehexamine-end poly(ethylene glycol) (mPEG-N6) for active-ester surface.
|
Colloids Surf B Biointerfaces
|
2011
|
0.76
|
|
75
|
Improved complementary polymer pair system: switching for enzyme activity by PEGylated polymers.
|
Langmuir
|
2012
|
0.76
|
|
76
|
Stimuli-responsive smart nanogels for cancer diagnostics and therapy.
|
Nanomedicine (Lond)
|
2010
|
0.76
|
|
77
|
A design of nanosized PEGylated-latex mixed polymer solution for microchip electrophoresis.
|
Lab Chip
|
2004
|
0.76
|
|
78
|
Fluorescence-based affinity labeling of nucleobase by hydrogen-bond forming metal complex.
|
Nucleic Acids Symp Ser (Oxf)
|
2007
|
0.75
|
|
79
|
Oral nanotherapeutics: effect of redox nanoparticle on microflora in mice with dextran sodium sulfate-induced colitis.
|
J Gastroenterol
|
2013
|
0.75
|
|
80
|
Development of a high-performance immunolatex based on "soft landing" antibody immobilization mechanism.
|
Colloids Surf B Biointerfaces
|
2011
|
0.75
|
|
81
|
Design and preparation of a nanoprobe for imaging inflammation sites.
|
Biointerphases
|
2012
|
0.75
|
|
82
|
Binding enhancement of antigen-functionalized PEGylated gold nanoparticles onto antibody-immobilized surface by increasing the functionalized antigen using alpha-sulfanyl-omega-amino-PEG.
|
Chem Commun (Camb)
|
2008
|
0.75
|
|
83
|
Efficient inhibition of interfacial nonspecific interaction to create practically utilizable high ferritin-response immunolatex.
|
Anal Chem
|
2009
|
0.75
|
|
84
|
Silica-installed redox nanoparticles for novel oral nanotherapeutics - improvement in intestinal delivery with anti-inflammatory effects.
|
J Drug Target
|
2014
|
0.75
|
|
85
|
TEMPOL protects human neuroblastoma SH-SY5Y cells against β-amyloid-induced cell toxicity.
|
Eur J Pharmacol
|
2010
|
0.75
|
|
86
|
Indomethacin-loaded redox nanoparticles improve oral bioavailability of indomethacin and suppress its small intestinal inflammation.
|
Ther Deliv
|
2014
|
0.75
|
|
87
|
Colloidal Au replacement assay for highly sensitive quantification of low molecular weight analytes by surface plasmon resonance.
|
Bioconjug Chem
|
2007
|
0.75
|
|
88
|
Physicochemical characterization of densely packed poly(ethylene glycol) layer for minimizing nonspecific protein adsorption.
|
J Nanosci Nanotechnol
|
2007
|
0.75
|
|
89
|
Novel protein PEGylation chemistry via glutalaldehyde-functionalized PEG.
|
Bioconjug Chem
|
2013
|
0.75
|
|
90
|
Simple solid-phase synthesis and biological properties of carbohydrate-oligonucleotide conjugates modified at the 3'-terminus.
|
Bioconjug Chem
|
2010
|
0.75
|
|
91
|
Improving the heat resistance of ribonuclease A by the addition of poly(N,N-diethylaminoethyl methacrylate)-graft-poly(ethylene glycol) (PEAMA-g-PEG).
|
Macromol Biosci
|
2010
|
0.75
|
|
92
|
Novel oligonucleotide carrier as scavenger for reactive oxygen species.
|
Macromol Biosci
|
2010
|
0.75
|
|
93
|
Synthesis and evaluation of the functional oligonucleotides-PEG conjugates.
|
Nucleic Acids Symp Ser (Oxf)
|
2004
|
0.75
|
|
94
|
Novel biocompatible nanoreactor for silica/gold hybrid nanoparticles preparation.
|
Colloids Surf B Biointerfaces
|
2012
|
0.75
|