Published in Cell Mol Neurobiol on December 07, 2006
Orally administered prion protein is incorporated by m cells and spreads into lymphoid tissues with macrophages in prion protein knockout mice. Am J Pathol (2011) 0.90
Gene expression alterations in Rocky Mountain elk infected with chronic wasting disease. Prion (2012) 0.81
Prion propagation and toxicity occur in vitro with two-phase kinetics specific to strain and neuronal type. J Virol (2012) 0.80
Anti-LRP/LR antibody W3 hampers peripheral PrPSc propagation in scrapie infected mice. Prion (2007) 0.80
Interactions of prion protein with intracellular proteins: so many partners and no consequences? Cell Mol Neurobiol (2009) 0.79
Toxic effects of intracerebral PrP antibody administration during the course of BSE infection in mice. Prion (2007) 0.78
The 37/67kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67kDa LR cell surface localization and interaction with the cellular prion protein. Sci Rep (2016) 0.77
Susceptibility of cell substrates to PrPSc infection and safety control measures related to biological and biotherapeutical products. Prion (2008) 0.75
Region-specific protein misfolding cyclic amplification reproduces brain tropism of prion strains. J Biol Chem (2017) 0.75
Novel proteinaceous infectious particles cause scrapie. Science (1982) 24.09
A new variant of Creutzfeldt-Jakob disease in the UK. Lancet (1996) 20.15
SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins. Science (1991) 12.93
Mice devoid of PrP are resistant to scrapie. Cell (1993) 11.46
Molecular biology of prion diseases. Science (1991) 10.83
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc Natl Acad Sci U S A (1993) 10.36
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature (1992) 9.01
Synthetic mammalian prions. Science (2004) 7.35
Identification of a protein that purifies with the scrapie prion. Science (1982) 7.00
In vitro generation of infectious scrapie prions. Cell (2005) 6.86
NMR structure of the mouse prion protein domain PrP(121-231). Nature (1996) 6.37
Self-replication and scrapie. Nature (1967) 6.01
Anchorless prion protein results in infectious amyloid disease without clinical scrapie. Science (2005) 5.52
Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell (1987) 5.12
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell (1986) 4.82
A novel progressive spongiform encephalopathy in cattle. Vet Rec (1987) 4.39
Does the agent of scrapie replicate without nucleic acid? Nature (1967) 4.14
Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible. Proc Natl Acad Sci U S A (1997) 4.10
The cellular prion protein binds copper in vivo. Nature (1998) 3.92
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing. Biochemistry (1993) 3.54
Chronic wasting disease of captive mule deer: a spongiform encephalopathy. J Wildl Dis (1980) 3.53
Structural clues to prion replication. Science (1994) 3.43
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease. Proc Natl Acad Sci U S A (2001) 3.39
Signal transduction through prion protein. Science (2000) 3.09
Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells. J Virol (1993) 3.07
Degenerative disease of the central nervous system in New Guinea; the endemic occurrence of kuru in the native population. N Engl J Med (1957) 3.07
Isolation of a tumor cell laminin receptor. Biochem Biophys Res Commun (1983) 3.05
Letter: Possible person-to-person transmission of Creutzfeldt-Jakob disease. N Engl J Med (1974) 3.03
The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9. J Virol (2006) 2.94
Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS. Nat Med (2005) 2.80
Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model. Nat Med (2005) 2.80
Prion protein is necessary for normal synaptic function. Nature (1994) 2.69
Porphyrin and phthalocyanine antiscrapie compounds. Science (2000) 2.54
Scrapie prion proteins are synthesized in neurons. Am J Pathol (1986) 2.54
Scrapie prion protein accumulation by scrapie-infected neuroblastoma cells abrogated by exposure to a prion protein antibody. Proc Natl Acad Sci U S A (2001) 2.53
Pathologic conformations of prion proteins. Annu Rev Biochem (1998) 2.50
High-affinity laminin receptor is a receptor for Sindbis virus in mammalian cells. J Virol (1992) 2.44
Prion protein gene variation among primates. J Mol Biol (1995) 2.43
The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells. Nat Med (1997) 2.33
Monoclonal antibodies inhibit prion replication and delay the development of prion disease. Nature (2003) 2.31
Altered circadian activity rhythms and sleep in mice devoid of prion protein. Nature (1996) 2.24
The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein. EMBO J (2001) 2.16
Scrapie prion rod formation in vitro requires both detergent extraction and limited proteolysis. J Virol (1991) 2.11
Identification of interaction domains of the prion protein with its 37-kDa/67-kDa laminin receptor. EMBO J (2001) 2.10
Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell (1990) 2.06
Prion protein conformation in a patient with sporadic fatal insomnia. N Engl J Med (1999) 2.04
Potent inhibition of scrapie-associated PrP accumulation by congo red. J Neurochem (1992) 2.00
Cross-linking cellular prion protein triggers neuronal apoptosis in vivo. Science (2004) 2.00
Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein. J Mol Biol (1999) 1.90
Normal prion protein has an activity like that of superoxide dismutase. Biochem J (1999) 1.87
Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines. Proc Natl Acad Sci U S A (1998) 1.80
Prophylactic potential of pentosan polysulphate in transmissible spongiform encephalopathies. Lancet (1999) 1.77
Prion protein protects human neurons against Bax-mediated apoptosis. J Biol Chem (2001) 1.77
The chemistry of scrapie infection: implications of the 'ice 9' metaphor. Chem Biol (1995) 1.76
A glycolipid-anchored prion protein is endocytosed via clathrin-coated pits. J Cell Biol (1994) 1.74
Fatal familial insomnia and dysautonomia with selective degeneration of thalamic nuclei. N Engl J Med (1986) 1.73
Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein. Biochem Biophys Res Commun (1995) 1.72
Effectiveness of anthracycline against experimental prion disease in Syrian hamsters. Science (1997) 1.70
Aggregates of scrapie-associated prion protein induce the cell-free conversion of protease-sensitive prion protein to the protease-resistant state. Chem Biol (1995) 1.68
Prolongation of scrapie incubation period by an injection of dextran sulphate 500 within the month before or after infection. J Gen Virol (1986) 1.66
A prion protein cycles between the cell surface and an endocytic compartment in cultured neuroblastoma cells. J Biol Chem (1993) 1.64
Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein. J Mol Biol (2001) 1.63
Stress-inducible protein 1 is a cell surface ligand for cellular prion that triggers neuroprotection. EMBO J (2002) 1.58
Nucleotide sequence for a major messenger RNA for a 40 kilodalton polypeptide that is under translational control in mouse tumor cells. Nucleic Acids Res (1988) 1.57
Copper binding to octarepeat peptides of the prion protein monitored by mass spectrometry. Protein Sci (2000) 1.57
Spongiform encephalopathy in an arabian oryx (Oryx leucoryx) and a greater kudu (Tragelaphus strepsiceros) Vet Rec (1990) 1.56
A putative receptor for Venezuelan equine encephalitis virus from mosquito cells. J Virol (1996) 1.56
Encephalopathy of mink. II. Experimental and natural transmission. J Infect Dis (1965) 1.53
Attempts to restore scrapie prion infectivity after exposure to protein denaturants. Proc Natl Acad Sci U S A (1993) 1.52
Prions in skeletal muscle. Proc Natl Acad Sci U S A (2002) 1.48
Chemoprophylaxis of scrapie in mice. J Gen Virol (1991) 1.45
Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study. Neurology (2004) 1.45
Complementary hydropathy identifies a cellular prion protein receptor. Nat Med (1997) 1.43
RNA aptamers specifically interact with the prion protein PrP. J Virol (1997) 1.43
Congo red prolongs the incubation period in scrapie-infected hamsters. J Virol (1995) 1.42
The abnormal isoform of the prion protein accumulates in late-endosome-like organelles in scrapie-infected mouse brain. J Pathol (1995) 1.40
Amphotericin B delays the incubation period of scrapie in intracerebrally inoculated hamsters. J Gen Virol (1987) 1.39
Imbalance of antioxidant defense in mice lacking cellular prion protein. Free Radic Biol Med (2001) 1.37
Functional domains of the 67-kDa laminin receptor precursor. J Biol Chem (1991) 1.35
Prion-protein-specific aptamer reduces PrPSc formation. Chembiochem (2002) 1.35
Cellular prion protein binds laminin and mediates neuritogenesis. Brain Res Mol Brain Res (2000) 1.34
Formation of the 67-kDa laminin receptor by acylation of the precursor. J Cell Biochem (1998) 1.34
The 67-kDa laminin receptor originated from a ribosomal protein that acquired a dual function during evolution. Mol Biol Evol (1998) 1.33
Assignment of the human and mouse prion protein genes to homologous chromosomes. Proc Natl Acad Sci U S A (1986) 1.33
Heparan sulfate is a cellular receptor for purified infectious prions. J Biol Chem (2005) 1.32
Branched polyamines cure prion-infected neuroblastoma cells. J Virol (2001) 1.32
A 33-kDa polypeptide with homology to the laminin receptor: component of translation machinery. Proc Natl Acad Sci U S A (1992) 1.31
Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease. EMBO J (2001) 1.29
AAV2-mediated gene delivery to monkey putamen: evaluation of an infusion device and delivery parameters. Exp Neurol (2005) 1.29
Cellular prion protein function in copper homeostasis and redox signalling at the synapse. J Neurochem (2003) 1.28
Prion protein PrPc interacts with molecular chaperones of the Hsp60 family. J Virol (1996) 1.28
Cell-surface prion protein interacts with glycosaminoglycans. Biochem J (2002) 1.27
Heparin-like molecules bind differentially to prion-proteins and change their intracellular metabolic fate. J Cell Physiol (1993) 1.26
PrP knock-out and PrP transgenic mice in prion research. Br Med Bull (2003) 1.26
Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP. Mol Biol Cell (2006) 1.25
Prions and prion proteins. FASEB J (1991) 1.23
Identification of candidate proteins binding to prion protein. Neurobiol Dis (1997) 1.23
The 37 kDa/67 kDa laminin receptor is required for PrP(Sc) propagation in scrapie-infected neuronal cells. EMBO Rep (2003) 1.23
Clearance and prevention of prion infection in cell culture by anti-PrP antibodies. Eur J Neurosci (2006) 1.22
Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor. EMBO J (2002) 2.22
The psychosocial burden of psoriasis. Am J Clin Dermatol (2005) 1.81
What kinesin does at roadblocks: the coordination mechanism for molecular walking. EMBO J (2003) 1.41
Identification of the heparan sulfate binding sites in the cellular prion protein. J Biol Chem (2002) 1.41
The 37 kDa/67 kDa laminin receptor is required for PrP(Sc) propagation in scrapie-infected neuronal cells. EMBO Rep (2003) 1.23
The 37-kDa/67-kDa laminin receptor acts as a receptor for infectious prions and is inhibited by polysulfated glycanes. J Infect Dis (2006) 1.20
Ectopic bone formation associated with mesenchymal stem cells in a resorbable calcium deficient hydroxyapatite carrier. Biomaterials (2005) 1.17
Invasion of tumorigenic HT1080 cells is impeded by blocking or downregulating the 37-kDa/67-kDa laminin receptor. J Mol Biol (2008) 1.14
Pan-European survey on the occurrence of selected polar organic persistent pollutants in ground water. Water Res (2010) 1.12
Bovine prion is endocytosed by human enterocytes via the 37 kDa/67 kDa laminin receptor. Am J Pathol (2005) 1.07
Matrix metalloproteinases and failed fracture healing. Bone (2005) 1.04
Clinical and radiological long-term results after operative treatment of chondroblastoma. Arch Orthop Trauma Surg (2010) 1.02
The amount of calcium-deficient hexagonal hydroxyapatite in aortic valves is influenced by gender and associated with genetic polymorphisms in patients with severe calcific aortic stenosis. Eur Heart J (2004) 1.01
Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor. Water Res (2005) 1.00
Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy. J Gen Virol (2008) 1.00
Influence of platelet-rich plasma on osteogenic differentiation of mesenchymal stem cells and ectopic bone formation in calcium phosphate ceramics. Cells Tissues Organs (2006) 0.95
LRP/LR as an alternative promising target in therapy of prion diseases, Alzheimer's disease and cancer. Infect Disord Drug Targets (2009) 0.94
Loosening after acetabular revision: comparison of trabecular metal and reinforcement rings. A systematic review. J Arthroplasty (2013) 0.92
Effect of platelet-rich plasma on the in vitro proliferation and osteogenic differentiation of human mesenchymal stem cells on distinct calcium phosphate scaffolds: the specific surface area makes a difference. J Biomater Appl (2008) 0.92
Therapeutic approaches for prion disorders. Expert Rev Anti Infect Ther (2007) 0.90
Progress in the palladium-catalyzed cyanation of aryl chlorides. Chemistry (2003) 0.88
Prion interaction with the 37-kDa/67-kDa laminin receptor on enterocytes as a cellular model for intestinal uptake of prions. J Mol Biol (2010) 0.88
Minimum ten-year results of a 28-mm metal-on-metal bearing in cementless total hip arthroplasty in patients fifty years of age and younger. Int Orthop (2013) 0.87
Polar pollutants entry into the water cycle by municipal wastewater: a European perspective. Environ Sci Technol (2006) 0.87
Microinjection of lentiviral vectors expressing small interfering RNAs directed against laminin receptor precursor mRNA prolongs the pre-clinical phase in scrapie-infected mice. J Gen Virol (2009) 0.86
10-year results of the uncemented Allofit press-fit cup in young patients. Acta Orthop (2014) 0.86
Functional and biophysical analyses of the class XIV Toxoplasma gondii myosin D. J Muscle Res Cell Motil (2006) 0.85
A trans-dominant negative 37kDa/67kDa laminin receptor mutant impairs PrP(Sc) propagation in scrapie-infected neuronal cells. J Mol Biol (2006) 0.85
Single chain Fv antibodies directed against the 37 kDa/67 kDa laminin receptor as therapeutic tools in prion diseases. Mol Immunol (2007) 0.84
Subcellular localization of prion proteins and the 37 kDa/67 kDa laminin receptor fused to fluorescent proteins. Biochim Biophys Acta (2008) 0.84
Scrapie-infected transgenic mice expressing a laminin receptor decoy mutant reveal a prolonged incubation time associated with low levels of PrPres. J Mol Biol (2009) 0.83
Data visualization in environmental proteomics. Proteomics (2013) 0.82
Comparison of sulfonated and other micropollutants removal in membrane bioreactor and conventional wastewater treatment. Water Res (2007) 0.82
Failed surgical reconstruction of patellar tendon aplasia. A report of two cases. J Bone Joint Surg Am (2005) 0.81
Different isoforms of the non-integrin laminin receptor are present in mouse brain and bind PrP. Biol Chem (2003) 0.80
Cellular prion protein/laminin receptor: distribution in adult central nervous system and characterization of an isoform associated with a subtype of cortical neurons. Eur J Neurosci (2004) 0.80
Anti-LRP/LR antibody W3 hampers peripheral PrPSc propagation in scrapie infected mice. Prion (2007) 0.80
Telephone counseling and attendance in a national mammography-screening program a randomized controlled trial. Am J Prev Med (2011) 0.79
The influence of cementing technique in hip resurfacing arthroplasty on the initial stability of the femoral component. Int Orthop (2011) 0.79
Knock-down of the 37-kDa/67-kDa laminin receptor in mouse brain by transgenic expression of specific antisense LRP RNA. Transgenic Res (2004) 0.79
Lower serum calcium levels are associated with greater calcium hydroxyapatite deposition in native aortic valves of male patients with severe calcific aortic stenosis. J Heart Valve Dis (2006) 0.79
Therapeutic approaches targeting the prion receptor LRP/LR. Vet Microbiol (2007) 0.79
The prion-like protein Doppel fails to interact with itself, the prion protein and the 37 kDa/67 kDa laminin receptor in the yeast two-hybrid system. Biochim Biophys Acta (2004) 0.78
Pollution gets personal! A first population-based human biomonitoring study in Austria. Int J Hyg Environ Health (2011) 0.78
High-level expression and characterization of a glycosylated covalently linked dimer of the prion protein. Protein Eng (2002) 0.77
Upregulation in rat spinal cord microglia of the nonintegrin laminin receptor 37 kDa-LRP following activation by a traumatic lesion or peripheral injury. J Neurotrauma (2009) 0.77
Prion protein-specific antibodies for therapeutic intervention of transmissible spongiform encephalopathies. Expert Opin Biol Ther (2006) 0.77
Quantitative determination of free intracellular alpha-keto acids in neutrophils. J Chromatogr B Analyt Technol Biomed Life Sci (2003) 0.77
Intra- and interspecies interactions between prion proteins and effects of mutations and polymorphisms. Biol Chem (2003) 0.77
Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis. Circ Cardiovasc Genet (2016) 0.75
Woodsmoke marker levoglucosan: kinetics in a self-experiment. Int J Occup Med Environ Health (2012) 0.75
Effects of propofol and taurine on intracellular free amino acid profiles and immune function markers in neutrophils in vitro. Clin Chem Lab Med (2002) 0.75
Electrochemical treatment of pharmaceutical wastewater by combining anodic oxidation with ozonation. J Environ Sci Health A Tox Hazard Subst Environ Eng (2008) 0.75
Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet (2017) 0.75
New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circ Cardiovasc Genet (2017) 0.75
Modular chemosensors from self-assembled vesicle membranes with amphiphilic binding sites and reporter dyes. Angew Chem Int Ed Engl (2010) 0.75
Correction to Nitrate Reverses Severe Nitrite Inhibition of Anaerobic Ammonium Oxidation (Anammox) Activity in Continuously-Fed Bioreactors. Environ Sci Technol (2016) 0.75
[Therapeutic approaches for treatment of Creutzfeldt-Jakob disease]. Med Monatsschr Pharm (2008) 0.75
Recombinant human prion protein mutants huPrP D178N/M129 (FFI) and huPrP+9OR (fCJD) reveal proteinase K resistance. J Cell Sci (2002) 0.75
Visualizing different uranium oxidation states during the surface alteration of uraninite and uranium tetrachloride. Naturwissenschaften (2009) 0.75
Recurrent episodes of stroke in a young adult: question. J Clin Neurosci (2016) 0.75