Allan J Zajac

Author PubWeight™ 43.63‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A vital role for interleukin-21 in the control of a chronic viral infection. Science 2009 4.55
2 Ablation of CD8 and CD4 T cell responses by high viral loads. J Immunol 2003 2.63
3 Memory CD4 T cells emerge from effector T-cell progenitors. Nature 2008 2.62
4 Cutting edge: emergence of CD127high functionally competent memory T cells is compromised by high viral loads and inadequate T cell help. J Immunol 2005 2.61
5 Maintenance, loss, and resurgence of T cell responses during acute, protracted, and chronic viral infections. J Immunol 2004 2.28
6 T-cell exhaustion: characteristics, causes and conversion. Immunology 2010 2.24
7 CD4 T cell-dependent CD8 T cell maturation. J Immunol 2004 2.04
8 Bim mediates apoptosis of CD127(lo) effector T cells and limits T cell memory. Eur J Immunol 2006 1.95
9 Codon usage optimization of HIV type 1 subtype C gag, pol, env, and nef genes: in vitro expression and immune responses in DNA-vaccinated mice. AIDS Res Hum Retroviruses 2003 1.73
10 Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells. J Immunol 2002 1.44
11 IL-21 deficiency influences CD8 T cell quality and recall responses following an acute viral infection. J Immunol 2010 1.28
12 Interleukin-21: a multifunctional regulator of immunity to infections. Microbes Infect 2010 1.17
13 Interleukin-21-producing HIV-1-specific CD8 T cells are preferentially seen in elite controllers. J Virol 2010 1.15
14 T cell responses to viral infections: lessons from lymphocytic choriomeningitis virus. Immunol Res 2002 1.09
15 Cytokines and the inception of CD8 T cell responses. Trends Immunol 2011 1.07
16 Rapid recruitment of virus-specific CD8 T cells restructures immunodominance during protective secondary responses. J Virol 2005 1.06
17 IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells. J Immunol 2013 0.99
18 Exhausted CD8 T cells downregulate the IL-18 receptor and become unresponsive to inflammatory cytokines and bacterial co-infections. PLoS Pathog 2011 0.94
19 Functionally competent antigen-specific CD127(hi) memory CD8+ T cells are preserved only in HIV-infected individuals receiving early treatment. J Infect Dis 2006 0.94
20 IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response. Diabetes 2011 0.92
21 Pronounced virus-dependent activation drives exhaustion but sustains IFN-γ transcript levels. J Immunol 2010 0.91
22 Interleukin-21 promotes germinal center reaction by skewing the follicular regulatory T cell to follicular helper T cell balance in autoimmune BXD2 mice. Arthritis Rheumatol 2014 0.91
23 Anti-viral CD8 T cells and the cytokines that they love. Virology 2013 0.91
24 ICAM-1-dependent tuning of memory CD8 T-cell responses following acute infection. Proc Natl Acad Sci U S A 2013 0.90
25 Temporal requirements for B cells in the establishment of CD4 T cell memory. J Immunol 2013 0.89
26 Elevated generation of reactive oxygen/nitrogen species in hantavirus cardiopulmonary syndrome. J Virol 2002 0.88
27 Shaping successful and unsuccessful CD8 T cell responses following infection. J Biomed Biotechnol 2010 0.87
28 IL-21 optimizes T cell and humoral responses in the central nervous system during viral encephalitis. J Neuroimmunol 2013 0.81
29 HIV-1(89.6) Gag expressed from a replication competent HSV-1 vector elicits persistent cellular immune responses in mice. Vaccine 2007 0.79
30 In vivo analysis of adenovirus-specific cytotoxic T lymphocyte response in mice deficient in CD28, fas ligand, and perforin. Hum Gene Ther 2006 0.79