Published in Glia on March 01, 2007
Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. PLoS One (2009) 1.70
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.57
Xeno-free defined conditions for culture of human embryonic stem cells, neural stem cells and dopaminergic neurons derived from them. PLoS One (2009) 1.38
Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions. PLoS One (2008) 1.36
Tissue- and cell-type-specific manifestations of heteroplasmic mtDNA 3243A>G mutation in human induced pluripotent stem cell-derived disease model. Proc Natl Acad Sci U S A (2013) 1.28
Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells. Hum Gene Ther (2011) 1.15
MEF2C enhances dopaminergic neuron differentiation of human embryonic stem cells in a parkinsonian rat model. PLoS One (2011) 1.09
Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease. PLoS One (2012) 1.02
Niche-dependent development of functional neuronal networks from embryonic stem cell-derived neural populations. BMC Neurosci (2009) 0.98
Generating regionalized neuronal cells from pluripotency, a step-by-step protocol. Front Cell Neurosci (2013) 0.95
Β-amyloid 1-42 oligomers impair function of human embryonic stem cell-derived forebrain cholinergic neurons. PLoS One (2010) 0.94
Regional differentiation of retinoic acid-induced human pluripotent embryonic carcinoma stem cell neurons. PLoS One (2011) 0.94
Nicotinamide rescues human embryonic stem cell-derived neuroectoderm from parthanatic cell death. Stem Cells (2009) 0.92
Neural stem cell specific fluorescent chemical probe binding to FABP7. Proc Natl Acad Sci U S A (2012) 0.92
Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells. J Cell Mol Med (2009) 0.89
Neurotrophic factors promote cholinergic differentiation in human embryonic stem cell-derived neurons. J Cell Mol Med (2009) 0.88
Facile engineering of xeno-free microcarriers for the scalable cultivation of human pluripotent stem cells in stirred suspension. Tissue Eng Part A (2013) 0.84
Culture conditions affect cardiac differentiation potential of human pluripotent stem cells. PLoS One (2012) 0.83
Manufacturing neurons from human embryonic stem cells: biological and regulatory aspects to develop a safe cellular product for stroke cell therapy. Regen Med (2009) 0.83
The cellular form of the prion protein guides the differentiation of human embryonic stem cells into neuron-, oligodendrocyte-, and astrocyte-committed lineages. Prion (2014) 0.80
Human pluripotent stem cell-derived radial glia recapitulate developmental events and provide real-time access to cortical neurons and astrocytes. Stem Cells Transl Med (2015) 0.79
Fibrillar β-amyloid 1-42 alters cytokine secretion, cholinergic signalling and neuronal differentiation. J Cell Mol Med (2014) 0.79
Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation. Stem Cells Int (2015) 0.79
Evaluation of neural gene expression in serum treated embryonic stem cells in Alzheimer's patients. J Res Med Sci (2013) 0.78
Analysis of human embryonic stem cells with regulatable expression of the cell adhesion molecule l1 in regeneration after spinal cord injury. J Neurotrauma (2014) 0.77
Neurogenic potential of hESC-derived human radial glia is amplified by human fetal cells. Stem Cell Res (2013) 0.77
LPA-primed astrocytes induce axonal outgrowth of cortical progenitors by activating PKA signaling pathways and modulating extracellular matrix proteins. Front Cell Neurosci (2014) 0.76
A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells. PLoS One (2015) 0.76
Generation of Functional Neuromuscular Junctions from Human Pluripotent Stem Cell Lines. Front Cell Neurosci (2015) 0.76
Concise review: animal substance-free human embryonic stem cells aiming at clinical applications. Stem Cells Transl Med (2014) 0.75
Techniques of Human Embryonic Stem Cell and Induced Pluripotent Stem Cell Derivation. Arch Immunol Ther Exp (Warsz) (2016) 0.75
Quantitative real-time imaging of glutathione. Nat Commun (2017) 0.75
Aggregate and Microcarrier Cultures of Human Pluripotent Stem Cells in Stirred-Suspension Systems. Methods Mol Biol (2016) 0.75
Engineering Xeno-Free Microcarriers with Recombinant Vitronectin, Albumin and UV Irradiation for Human Pluripotent Stem Cell Bioprocessing. ACS Biomater Sci Eng (2016) 0.75
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol (2004) 21.56
Mild cognitive impairment. Lancet (2006) 10.21
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA (2009) 7.29
An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurol (2004) 5.78
Two-year follow-up of amyloid deposition in patients with Alzheimer's disease. Brain (2006) 5.42
Alzheimer's disease: clinical trials and drug development. Lancet Neurol (2010) 4.65
Risk score for the prediction of dementia risk in 20 years among middle aged people: a longitudinal, population-based study. Lancet Neurol (2006) 4.54
The age-dependent relation of blood pressure to cognitive function and dementia. Lancet Neurol (2005) 4.54
Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch Neurol (2005) 4.49
PET imaging of amyloid deposition in patients with mild cognitive impairment. Neurobiol Aging (2007) 4.47
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
Leisure-time physical activity at midlife and the risk of dementia and Alzheimer's disease. Lancet Neurol (2005) 3.95
Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen project. Am J Epidemiol (2002) 3.70
Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511. Nat Biotechnol (2010) 3.70
A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas. Stem Cells (2007) 3.62
The worldwide economic impact of dementia 2010. Alzheimers Dement (2013) 3.23
The magnitude of dementia occurrence in the world. Alzheimer Dis Assoc Disord (2003) 3.23
Effect of rivastigmine on delay to diagnosis of Alzheimer's disease from mild cognitive impairment: the InDDEx study. Lancet Neurol (2007) 3.22
High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity. Nat Biotechnol (2010) 3.21
Twenty-year changes in dementia occurrence suggest decreasing incidence in central Stockholm, Sweden. Neurology (2013) 3.20
Heart failure and risk of dementia and Alzheimer disease: a population-based cohort study. Arch Intern Med (2006) 2.90
Prevalence of chronic diseases and multimorbidity among the elderly population in Sweden. Am J Public Health (2008) 2.86
The worldwide societal costs of dementia: Estimates for 2009. Alzheimers Dement (2010) 2.75
Pulse pressure and risk of Alzheimer disease in persons aged 75 years and older: a community-based, longitudinal study. Stroke (2003) 2.60
Patterns of chronic multimorbidity in the elderly population. J Am Geriatr Soc (2009) 2.54
Relation of education and occupation-based socioeconomic status to incident Alzheimer's disease. Am J Epidemiol (2004) 2.35
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae. Proc Natl Acad Sci U S A (2008) 2.30
Mental, physical and social components in leisure activities equally contribute to decrease dementia risk. Dement Geriatr Cogn Disord (2005) 2.19
The use of cholinesterase inhibitors and the risk of myocardial infarction and death: a nationwide cohort study in subjects with Alzheimer's disease. Eur Heart J (2013) 2.15
Low PiB PET retention in presence of pathologic CSF biomarkers in Arctic APP mutation carriers. Neurology (2012) 2.02
Association between mid-life marital status and cognitive function in later life: population based cohort study. BMJ (2009) 2.00
Gene expression signatures of seven individual human embryonic stem cell lines. Stem Cells (2005) 1.86
Person-centred care of people with severe Alzheimer's disease: current status and ways forward. Lancet Neurol (2008) 1.86
An estimate of the total worldwide societal costs of dementia in 2005. Alzheimers Dement (2007) 1.83
Derivation of human embryonic stem cell lines in serum replacement medium using postnatal human fibroblasts as feeder cells. Stem Cells (2005) 1.82
Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells. Hum Mol Genet (2010) 1.79
A longitudinal study integrating population, care and social services data. The Swedish National study on Aging and Care (SNAC). Aging Clin Exp Res (2004) 1.78
Mild cognitive impairment in the general population: occurrence and progression to Alzheimer disease. Am J Geriatr Psychiatry (2008) 1.77
Imaging markers for Alzheimer disease: which vs how. Neurology (2013) 1.76
Good manufacturing practice and clinical-grade human embryonic stem cell lines. Hum Mol Genet (2008) 1.76
Serum lipids and hippocampal volume: the link to Alzheimer's disease? Ann Neurol (2004) 1.72
Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells. In Vitro Cell Dev Biol Anim (2010) 1.70
The liver X receptor-{beta} is essential for maintaining cholesterol homeostasis in the testis. Endocrinology (2005) 1.69
Anaemia increases the risk of dementia in cognitively intact elderly. Neurobiol Aging (2006) 1.65
Detection of Alzheimer's disease and dementia in the preclinical phase: population based cohort study. BMJ (2003) 1.65
Late-life body mass index and dementia incidence: nine-year follow-up data from the Kungsholmen Project. J Am Geriatr Soc (2007) 1.65
Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease. Am J Pathol (2003) 1.64
The effect of borderline diabetes on the risk of dementia and Alzheimer's disease. Diabetes (2007) 1.62
A gene expression signature shared by human mature oocytes and embryonic stem cells. BMC Genomics (2009) 1.58
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.57
Differential evolution of cognitive impairment in nondemented older persons: results from the Kungsholmen Project. Am J Psychiatry (2002) 1.55
Vitrification versus controlled-rate freezing in cryopreservation of human ovarian tissue. Hum Reprod (2009) 1.55
Levels of mTOR and its downstream targets 4E-BP1, eEF2, and eEF2 kinase in relationships with tau in Alzheimer's disease brain. FEBS J (2005) 1.54
Partial purification and characterization of gamma-secretase from post-mortem human brain. J Biol Chem (2003) 1.54
Cryopreservation and autotransplantation of human ovarian tissue prior to cytotoxic therapy--a technique in its infancy but already successful in fertility preservation. Eur J Cancer (2009) 1.52
A nine-transmembrane domain topology for presenilin 1. J Biol Chem (2005) 1.52
Transcriptome profiling of human pre-implantation development. PLoS One (2009) 1.51
Prediction of dementia in MCI patients based on core diagnostic markers for Alzheimer disease. Neurology (2013) 1.51
Alcohol drinking in middle age and subsequent risk of mild cognitive impairment and dementia in old age: a prospective population based study. BMJ (2004) 1.51
Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease. J Lipid Res (2003) 1.50
Effect of phenserine treatment on brain functional activity and amyloid in Alzheimer's disease. Ann Neurol (2008) 1.50
Mechanical isolation of the inner cell mass is effective in derivation of new human embryonic stem cell lines. Hum Reprod (2007) 1.50
Transplantation of human embryonic stem cell-derived neural precursor cells and enriched environment after cortical stroke in rats: cell survival and functional recovery. Eur J Neurosci (2009) 1.49
Abeta43 is more frequent than Abeta40 in amyloid plaque cores from Alzheimer disease brains. J Neurochem (2009) 1.48
Determinants of costs of care for patients with Alzheimer's disease. Int J Geriatr Psychiatry (2006) 1.47
Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease. Acta Neuropathol (2010) 1.46
The zebrafish transcriptome during early development. BMC Dev Biol (2011) 1.39
A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells. PLoS One (2010) 1.39
Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria. J Biol Chem (2004) 1.39
Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment. Hum Reprod (2007) 1.38
CD marker expression profiles of human embryonic stem cells and their neural derivatives, determined using flow-cytometric analysis, reveal a novel CD marker for exclusion of pluripotent stem cells. Stem Cell Res (2008) 1.37
APOE genotype, family history of dementia, and Alzheimer disease risk: a 6-year follow-up study. Arch Neurol (2004) 1.36
Low blood pressure and risk of dementia in the Kungsholmen project: a 6-year follow-up study. Arch Neurol (2003) 1.36
Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice. J Neuroimmunol (2002) 1.36
The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity. Neurobiol Dis (2012) 1.35
Patient- and proxy-reported utility in Alzheimer disease using the EuroQoL. Alzheimer Dis Assoc Disord (2006) 1.35
Cingulate cortex hypoperfusion predicts Alzheimer's disease in mild cognitive impairment. BMC Neurol (2002) 1.34
A role for the androgen receptor in follicular atresia of estrogen receptor beta knockout mouse ovary. Biol Reprod (2002) 1.31
Review of Alzheimer's disease scales: is there a need for a new multi-domain scale for therapy evaluation in medical practice? Alzheimers Res Ther (2010) 1.30
The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimer's disease risk: a prospective cohort study. J Alzheimers Dis (2011) 1.30
Testing of nine different xeno-free culture media for human embryonic stem cell cultures. Hum Reprod (2007) 1.30
In vivo amyloid imaging with PET in frontotemporal dementia. Eur J Nucl Med Mol Imaging (2007) 1.29
A critical discussion of the role of neuroimaging in mild cognitive impairment. Acta Neurol Scand Suppl (2003) 1.29
Recommendations for fertility preservation in patients with lymphoma, leukemia, and breast cancer. J Assist Reprod Genet (2012) 1.28
Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease. Brain Res Mol Brain Res (2002) 1.27
Biomarkers for Alzheimer's disease therapeutic trials. Prog Neurobiol (2010) 1.26
Toward the defined and xeno-free differentiation of functional human pluripotent stem cell-derived retinal pigment epithelial cells. Mol Vis (2011) 1.25
Expression analysis of the NLRP gene family suggests a role in human preimplantation development. PLoS One (2008) 1.25
Dynamic changes in PET amyloid and FDG imaging at different stages of Alzheimer's disease. Neurobiol Aging (2010) 1.24
APOE-related mortality: effect of dementia, cardiovascular disease and gender. Neurobiol Aging (2008) 1.23
Growth differentiation factor-9 promotes the growth, development, and survival of human ovarian follicles in organ culture. J Clin Endocrinol Metab (2002) 1.23
Culture conditions for human embryonic stem cells. Reproduction (2006) 1.23
The impact of somatic and cognitive disorders on the functional status of the elderly. J Clin Epidemiol (2002) 1.20