Published in Hum Mol Genet on December 03, 2010
The ontogeny of cKIT+ human primordial germ cells proves to be a resource for human germ line reprogramming, imprint erasure and in vitro differentiation. Nat Cell Biol (2012) 2.41
Generation of haploid spermatids with fertilization and development capacity from human spermatogonial stem cells of cryptorchid patients. Stem Cell Reports (2014) 1.50
Direct differentiation of human pluripotent stem cells into haploid spermatogenic cells. Cell Rep (2012) 1.40
Induced pluripotent stem cells from highly endangered species. Nat Methods (2011) 1.24
Divergent RNA-binding proteins, DAZL and VASA, induce meiotic progression in human germ cells derived in vitro. Stem Cells (2012) 1.23
Very small embryonic-like stem cells: implications in reproductive biology. Biomed Res Int (2013) 1.07
Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile. EMBO J (2015) 1.01
Fate of iPSCs derived from azoospermic and fertile men following xenotransplantation to murine seminiferous tubules. Cell Rep (2014) 0.99
In vitro spermatogenesis: A long journey to get tails. Spermatogenesis (2012) 0.97
Germline stem cells: toward the regeneration of spermatogenesis. Fertil Steril (2013) 0.96
Multiplex parenting: IVG and the generations to come. J Med Ethics (2014) 0.95
Meiotic competent human germ cell-like cells derived from human embryonic stem cells induced by BMP4/WNT3A signaling and OCT4/EpCAM (epithelial cell adhesion molecule) selection. J Biol Chem (2012) 0.94
Experimental methods to preserve male fertility and treat male factor infertility. Fertil Steril (2015) 0.91
Fate of induced pluripotent stem cells following transplantation to murine seminiferous tubules. Hum Mol Genet (2014) 0.91
Chemoablated mouse seminiferous tubular cells enriched for very small embryonic-like stem cells undergo spontaneous spermatogenesis in vitro. Reprod Biol Endocrinol (2015) 0.90
Fruitful progress to fertility: male fertility in the test tube. Nat Med (2011) 0.89
Stem cell therapeutic possibilities: future therapeutic options for male-factor and female-factor infertility? Reprod Biomed Online (2013) 0.88
Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies. Sci Rep (2014) 0.85
Biotechnological approaches to the treatment of aspermatogenic men. Clinics (Sao Paulo) (2013) 0.85
Aberrant gene expression profiles in pluripotent stem cells induced from fibroblasts of a Klinefelter syndrome patient. J Biol Chem (2012) 0.85
Differentiation of induced pluripotent stem cells into male germ cells in vitro through embryoid body formation and retinoic acid or testosterone induction. Biomed Res Int (2012) 0.83
Retinoic Acid Is Sufficient for the In Vitro Induction of Mouse Spermatocytes. Stem Cell Reports (2016) 0.83
Generation and characterization of human cryptorchid-specific induced pluripotent stem cells from urine. Stem Cells Dev (2013) 0.83
Effect of Rat Medicated Serum Containing Zuo Gui Wan and/or You Gui Wan on the Differentiation of Stem Cells Derived from Human First Trimester Umbilical Cord into Oocyte-Like Cells In Vitro. Evid Based Complement Alternat Med (2015) 0.81
Germ cell differentiation from pluripotent cells. Semin Reprod Med (2013) 0.81
Recreating the female reproductive tract in vitro using iPSC technology in a linked microfluidics environment. Stem Cell Res Ther (2013) 0.81
A dose-dependent function of follicular fluid on the proliferation and differentiation of umbilical cord mesenchymal stem cells (MSCs) of goat. Histochem Cell Biol (2012) 0.81
Artificial gametes from stem cells. Clin Exp Reprod Med (2015) 0.81
In vitro differentiation of germ cells from stem cells: a comparison between primordial germ cells and in vitro derived primordial germ cell-like cells. Cell Death Dis (2015) 0.81
hiPSC-derived iMSCs: NextGen MSCs as an advanced therapeutically active cell resource for regenerative medicine. J Cell Mol Med (2016) 0.80
Creating human germ cells for unmet reproductive needs. Nat Biotechnol (2016) 0.80
Induced pluripotent stem cells: Mechanisms, achievements and perspectives in farm animals. World J Stem Cells (2015) 0.80
Characterization of embryonic stem-like cells derived from HEK293T cells through miR302/367 expression and their potentiality to differentiate into germ-like cells. Cytotechnology (2013) 0.78
Amniotic fluid stem cell-based models to study the effects of gene mutations and toxicants on male germ cell formation. Asian J Androl (2012) 0.78
Human somatic cells subjected to genetic induction with six germ line-related factors display meiotic germ cell-like features. Sci Rep (2016) 0.77
Stem cells derived from human first-trimester umbilical cord have the potential to differentiate into oocyte-like cells in vitro. Int J Mol Med (2015) 0.77
Downregulation of Col1a1 induces differentiation in mouse spermatogonia. Asian J Androl (2012) 0.77
Differentiation of early germ cells from human skin-derived stem cells without exogenous gene integration. Sci Rep (2015) 0.77
Adult somatic cells to the rescue: nuclear reprogramming and the dispensability of gonadal germ cells. Fertil Steril (2014) 0.77
Gamete derivation from embryonic stem cells, induced pluripotent stem cells or somatic cell nuclear transfer-derived embryonic stem cells: state of the art. Reprod Fertil Dev (2014) 0.76
Derivation of integration-free iPSCs from a Klinefelter syndrome patient. Reprod Med Biol (2015) 0.76
Differentiation of stem cells upon deprivation of exogenous FGF2: a general approach to study spontaneous differentiation of hESCs in vitro. Syst Biol Reprod Med (2012) 0.76
A Combination of Culture Conditions and Gene Expression Analysis Can Be Used to Investigate and Predict hES Cell Differentiation Potential towards Male Gonadal Cells. PLoS One (2015) 0.76
Induced pluripotent stem cell generation from a man carrying a complex chromosomal rearrangement as a genetic model for infertility studies. Sci Rep (2017) 0.75
Retracted In vitro derivation of mammalian germ cells from stem cells and their potential therapeutic application. Cell Mol Life Sci (2015) 0.75
Induction of Germ Cell-like Cells from Porcine Induced Pluripotent Stem Cells. Sci Rep (2016) 0.75
Induced pluripotent stem cell potential in medicine, specifically focused on reproductive medicine. Front Surg (2014) 0.75
Gametogenesis in a dish. Cell Res (2012) 0.75
Insights into female germ cell biology: from in vivo development to in vitro derivations. Asian J Androl (2015) 0.75
Retinoic acid combined with spermatogonial stem cell conditions facilitate the generation of mouse germ-like cells. Biosci Rep (2017) 0.75
Skin-derived stem cells as a source of primordial germ cell- and oocyte-like cells. Cell Death Dis (2016) 0.75
Assessing reproductive toxicity of two environmental toxicants with a novel in vitro human spermatogenic model. Stem Cell Res (2015) 0.75
Reconstituting mammalian spermatogenesis using stem cells. Asian J Androl (2011) 0.75
Human iPS Cell-Derived Germ Cells: Current Status and Clinical Potential. J Clin Med (2014) 0.75
Male germ-like cell differentiation potential of human umbilical cord Wharton's jelly-derived mesenchymal stem cells in co-culture with human placenta cells in presence of BMP4 and retinoic acid. Iran J Basic Med Sci (2015) 0.75
Over Expression of NANOS3 and DAZL in Human Embryonic Stem Cells. PLoS One (2016) 0.75
Progress and future prospect of in vitro spermatogenesis. Oncotarget (2017) 0.75
Epigenetic regulation during the differentiation of stem cells to germ cells. Oncotarget (2017) 0.75
Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell (2007) 101.42
Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50
Generation of germline-competent induced pluripotent stem cells. Nature (2007) 32.77
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol (2007) 21.93
The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Nature (2003) 12.44
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature (2009) 11.27
To err (meiotically) is human: the genesis of human aneuploidy. Nat Rev Genet (2001) 9.08
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell (2009) 8.97
Induction of pluripotent stem cells from fibroblast cultures. Nat Protoc (2007) 7.01
The rapid evolution of reproductive proteins. Nat Rev Genet (2002) 6.88
Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell (2007) 6.62
A molecular programme for the specification of germ cell fate in mice. Nature (2002) 5.67
Population study of causes, treatment, and outcome of infertility. Br Med J (Clin Res Ed) (1985) 5.48
Diverse spermatogenic defects in humans caused by Y chromosome deletions encompassing a novel RNA-binding protein gene. Nat Genet (1995) 5.02
Rapid evolution of reproductive isolation in the wild: evidence from introduced salmon. Science (2000) 5.00
Severe oligozoospermia resulting from deletions of azoospermia factor gene on Y chromosome. Lancet (1996) 4.28
Human Y chromosome azoospermia factors (AZF) mapped to different subregions in Yq11. Hum Mol Genet (1996) 3.78
Generation of induced pluripotent stem cells from adult rhesus monkey fibroblasts. Cell Stem Cell (2008) 3.15
Sex matters in meiosis. Science (2002) 2.98
Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation. Nature (2009) 2.79
The human VASA gene is specifically expressed in the germ cell lineage. Proc Natl Acad Sci U S A (2000) 2.56
Spontaneous differentiation of germ cells from human embryonic stem cells in vitro. Hum Mol Genet (2004) 2.35
Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. Stem Cells (2009) 1.94
Pluripotency and nuclear reprogramming. Philos Trans R Soc Lond B Biol Sci (2008) 1.82
Bone morphogenetic proteins induce germ cell differentiation from human embryonic stem cells. Stem Cells Dev (2006) 1.73
Vasa homolog genes in mammalian germ cell development. Cell Struct Funct (2001) 1.69
Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma. Stem Cells (2004) 1.56
Isolation of primordial germ cells from differentiating human embryonic stem cells. Stem Cells (2008) 1.43
A novel approach for the derivation of putative primordial germ cells and sertoli cells from human embryonic stem cells. Stem Cells (2009) 1.39
Turner syndrome: the case of the missing sex chromosome. Trends Genet (1993) 1.27
Derivation, characterization and differentiation of human embryonic stem cells: comparing serum-containing versus serum-free media and evidence of germ cell differentiation. Hum Reprod (2006) 1.23
Defective recombination in infertile men. Hum Mol Genet (2004) 1.22
Enrichment and differentiation of human germ-like cells mediated by feeder cells and basic fibroblast growth factor signaling. Stem Cells (2008) 1.17
Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes. Chromosoma (2004) 1.14
Instructing an embryonic stem cell-derived oocyte fate: lessons from endogenous oogenesis. Endocr Rev (2009) 1.06
The X chromosome and ovarian failure. Clin Endocrinol (Oxf) (1999) 0.85
Recombination in men with Klinefelter syndrome. Reproduction (2005) 0.84
Mapping of the POF1 locus and identification of putative genes for premature ovarian failure. Mol Hum Reprod (2000) 0.84
Estimating the incidence and prevalence and analyzing the correlates of infertility and sterility. Ann N Y Acad Sci (1994) 0.83
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nat Biotechnol (2007) 9.36
In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation (2006) 4.48
A nonviral minicircle vector for deriving human iPS cells. Nat Methods (2010) 4.42
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol (2011) 3.97
LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell (2011) 3.78
Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511. Nat Biotechnol (2010) 3.70
Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell (2012) 3.66
A meta-analysis of human embryonic stem cells transcriptome integrated into a web-based expression atlas. Stem Cells (2007) 3.62
Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. Proc Natl Acad Sci U S A (2009) 3.57
Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Sci Transl Med (2012) 3.53
Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage. Nat Biotechnol (2010) 3.22
High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity. Nat Biotechnol (2010) 3.21
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat Biotechnol (2011) 3.05
Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells. PLoS One (2010) 2.86
Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS One (2008) 2.85
Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation. Nature (2009) 2.79
Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells. J Clin Invest (2011) 2.69
Imaging survival and function of transplanted cardiac resident stem cells. J Am Coll Cardiol (2009) 2.58
Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. Circulation (2013) 2.57
Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein. Mol Cell Biol (2004) 2.53
MicroRNA profiling of human-induced pluripotent stem cells. Stem Cells Dev (2009) 2.44
Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells. Cell Stem Cell (2011) 2.35
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. Cell Stem Cell (2013) 2.33
MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. Circulation (2010) 2.32
Effects of cell number on teratoma formation by human embryonic stem cells. Cell Cycle (2009) 2.30
Network analysis of human in-stent restenosis. Circulation (2006) 2.27
Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts. Proc Natl Acad Sci U S A (2008) 2.25
Dynamic microRNA expression programs during cardiac differentiation of human embryonic stem cells: role for miR-499. Circ Cardiovasc Genet (2010) 2.24
Comparison of different adult stem cell types for treatment of myocardial ischemia. Circulation (2008) 2.22
Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation (2007) 2.21
Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair. J Am Coll Cardiol (2012) 2.18
CTCF interacts with and recruits the largest subunit of RNA polymerase II to CTCF target sites genome-wide. Mol Cell Biol (2007) 2.07
Patient-specific stem cells and cardiovascular drug discovery. JAMA (2013) 2.06
Dissecting the molecular relationship among various cardiogenic progenitor cells. Circ Res (2013) 2.06
Isolation and characterization of pluripotent human spermatogonial stem cell-derived cells. Stem Cells (2009) 2.05
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature (2011) 2.03
Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up. Circ Res (2012) 2.02
Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arterioscler Thromb Vasc Biol (2011) 1.93
Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. Stem Cells (2007) 1.93
Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects. Stem Cells (2008) 1.90
Gene expression signatures of seven individual human embryonic stem cell lines. Stem Cells (2005) 1.86
Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging. Circ Res (2012) 1.84
Multimodality cardiovascular molecular imaging, Part II. Circ Cardiovasc Imaging (2009) 1.82
Derivation of human embryonic stem cell lines in serum replacement medium using postnatal human fibroblasts as feeder cells. Stem Cells (2005) 1.82
In vivo functional and transcriptional profiling of bone marrow stem cells after transplantation into ischemic myocardium. Arterioscler Thromb Vasc Biol (2011) 1.80
Cyclin-dependent kinase directly regulates initiation of meiotic recombination. Cell (2006) 1.79
Quantum dot imaging for embryonic stem cells. BMC Biotechnol (2007) 1.78
Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell (2004) 1.76
Good manufacturing practice and clinical-grade human embryonic stem cell lines. Hum Mol Genet (2008) 1.76
Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation. Circ Res (2012) 1.74
Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart. Transplantation (2009) 1.73
Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells. In Vitro Cell Dev Biol Anim (2010) 1.70
The liver X receptor-{beta} is essential for maintaining cholesterol homeostasis in the testis. Endocrinology (2005) 1.69
Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation. Stem Cells Dev (2007) 1.65
Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction. PLoS One (2009) 1.64
DNA methylation presents distinct binding sites for human transcription factors. Elife (2013) 1.63
Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage. Nat Commun (2012) 1.62
Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation. Cloning Stem Cells (2007) 1.62
A gene expression signature shared by human mature oocytes and embryonic stem cells. BMC Genomics (2009) 1.58
Early removal of chest drainage after videothoracoscopic lung biopsy. Interact Cardiovasc Thorac Surg (2006) 1.58
Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging. Stem Cells (2009) 1.58
Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells. Proc Natl Acad Sci U S A (2009) 1.57
Positron emission tomography imaging of conditional gene activation in the heart. J Mol Cell Cardiol (2007) 1.56
Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma. Stem Cells (2004) 1.56
Vitrification versus controlled-rate freezing in cryopreservation of human ovarian tissue. Hum Reprod (2009) 1.55
Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays. Circulation (2013) 1.54
Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction. Circulation (2009) 1.54
Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns. Nat Protoc (2012) 1.53
Cryopreservation and autotransplantation of human ovarian tissue prior to cytotoxic therapy--a technique in its infancy but already successful in fertility preservation. Eur J Cancer (2009) 1.52
Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. FASEB J (2005) 1.52
Neurogenic neuroepithelial and radial glial cells generated from six human embryonic stem cell lines in serum-free suspension and adherent cultures. Glia (2007) 1.51
Transcriptome profiling of human pre-implantation development. PLoS One (2009) 1.51
Mechanical isolation of the inner cell mass is effective in derivation of new human embryonic stem cell lines. Hum Reprod (2007) 1.50
Molecular imaging of bone marrow mononuclear cell survival and homing in murine peripheral artery disease. JACC Cardiovasc Imaging (2012) 1.49
Transplantation of human embryonic stem cell-derived neural precursor cells and enriched environment after cortical stroke in rats: cell survival and functional recovery. Eur J Neurosci (2009) 1.49
Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation. Circulation (2011) 1.48
Enhanced generation of induced pluripotent stem cells from a subpopulation of human fibroblasts. PLoS One (2009) 1.47
In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation. Stem Cells Dev (2008) 1.46
Novel minicircle vector for gene therapy in murine myocardial infarction. Circulation (2009) 1.45
Human pre-implantation embryo development. Development (2012) 1.44
Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury. Stroke (2010) 1.44
Chronotherapeutics (light and wake therapy) in affective disorders. Psychol Med (2005) 1.42
Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion. Arterioscler Thromb Vasc Biol (2010) 1.42
MicroRNA-302 increases reprogramming efficiency via repression of NR2F2. Stem Cells (2013) 1.41
The zebrafish transcriptome during early development. BMC Dev Biol (2011) 1.39
A defined and xeno-free culture method enabling the establishment of clinical-grade human embryonic, induced pluripotent and adipose stem cells. PLoS One (2010) 1.39
Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind. Genomics (2005) 1.39
Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment. Hum Reprod (2007) 1.38