Published in Mol Cell Neurosci on December 05, 2006
Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function. Dev Cell (2011) 1.77
Evidence for retrogene origins of the prion gene family. PLoS One (2011) 0.92
Neurturin overexpression in skin enhances expression of TRPM8 in cutaneous sensory neurons and leads to behavioral sensitivity to cool and menthol. J Neurosci (2013) 0.88
GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates. Nat Med (2017) 0.86
Characterization of Drosophila GDNF receptor-like and evidence for its evolutionarily conserved interaction with neural cell adhesion molecule (NCAM)/FasII. PLoS One (2012) 0.81
GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway. Cell Rep (2016) 0.78
Solution structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1. BMC Biochem (2015) 0.76
Growth arrest specific 1 (GAS1) is abundantly expressed in the adult mouse central nervous system. J Histochem Cytochem (2013) 0.76
The Pfam protein families database. Nucleic Acids Res (2009) 37.98
The Pfam protein families database. Nucleic Acids Res (2011) 33.46
Pfam: the protein families database. Nucleic Acids Res (2013) 22.48
Exhaustive enumeration of protein domain families. J Mol Biol (2003) 4.95
A large-scale evaluation of computational protein function prediction. Nat Methods (2013) 4.61
Advances and pitfalls of protein structural alignment. Curr Opin Struct Biol (2009) 4.17
Cation-chloride cotransporters and neuronal function. Neuron (2009) 3.95
An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers. Neuron (2009) 3.34
ADDA: a domain database with global coverage of the protein universe. Nucleic Acids Res (2005) 2.65
The global trace graph, a novel paradigm for searching protein sequence databases. Bioinformatics (2007) 2.52
PairsDB atlas of protein sequence space. Nucleic Acids Res (2007) 2.42
BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion. J Cell Biol (2002) 2.40
KCC2 interacts with the dendritic cytoskeleton to promote spine development. Neuron (2007) 2.37
Sensitive pattern discovery with 'fuzzy' alignments of distantly related proteins. Bioinformatics (2003) 1.99
Unraveling protein interaction networks with near-optimal efficiency. Nat Biotechnol (2003) 1.93
A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system. Genomics (2003) 1.67
Bayesian search of functionally divergent protein subgroups and their function specific residues. Bioinformatics (2006) 1.51
PSIbase: a database of Protein Structural Interactome map (PSIMAP). Bioinformatics (2005) 1.42
A novel N-terminal isoform of the neuron-specific K-Cl cotransporter KCC2. J Biol Chem (2007) 1.26
Patterns of cation-chloride cotransporter expression during embryonic rodent CNS development. Eur J Neurosci (2002) 1.26
POBO, transcription factor binding site verification with bootstrapping. Nucleic Acids Res (2004) 1.25
Two novel mammalian Nogo receptor homologs differentially expressed in the central and peripheral nervous systems. Mol Cell Neurosci (2003) 1.21
Early growth response 4 mediates BDNF induction of potassium chloride cotransporter 2 transcription. J Neurosci (2011) 1.18
Behavioural phenotypes of hypomorphic KCC2-deficient mice. Eur J Neurosci (2005) 1.16
Deficient nonpeptidergic epidermis innervation and reduced inflammatory pain in glial cell line-derived neurotrophic factor family receptor alpha2 knock-out mice. J Neurosci (2006) 1.13
GFR alpha2/neurturin signalling regulates noxious heat transduction in isolectin B4-binding mouse sensory neurons. J Physiol (2002) 1.13
Evolution of the GDNF family ligands and receptors. Brain Behav Evol (2006) 1.09
Characterization of myelin ligand complexes with neuronal Nogo-66 receptor family members. J Biol Chem (2006) 1.07
Defense-related transcription factors WRKY70 and WRKY54 modulate osmotic stress tolerance by regulating stomatal aperture in Arabidopsis. New Phytol (2013) 1.07
Automated detection of remote homology. Curr Opin Struct Biol (2002) 1.02
Coexpression and heteromerization of two neuronal K-Cl cotransporter isoforms in neonatal brain. J Biol Chem (2009) 1.00
Oligomerization of hantavirus nucleocapsid protein: analysis of the N-terminal coiled-coil domain. J Virol (2006) 0.99
Revised phylogeny and novel horizontally acquired virulence determinants of the model soft rot phytopathogen Pectobacterium wasabiae SCC3193. PLoS Pathog (2012) 0.98
Robust extraction of functional signals from gene set analysis using a generalized threshold free scoring function. BMC Bioinformatics (2009) 0.98
MPEA--metabolite pathway enrichment analysis. Bioinformatics (2011) 0.96
Alimentary tract innervation deficits and dysfunction in mice lacking GDNF family receptor alpha2. J Clin Invest (2003) 0.96
Generation of Gene Ontology benchmark datasets with various types of positive signal. BMC Bioinformatics (2009) 0.96
Towards structured output prediction of enzyme function. BMC Proc (2008) 0.95
BLANNOTATOR: enhanced homology-based function prediction of bacterial proteins. BMC Bioinformatics (2012) 0.94
Parasympathetic innervation and function of endocrine pancreas requires the glial cell line-derived factor family receptor alpha2 (GFRalpha2). Diabetes (2005) 0.93
POXO: a web-enabled tool series to discover transcription factor binding sites. Nucleic Acids Res (2006) 0.92
Accurate detection of very sparse sequence motifs. J Comput Biol (2004) 0.91
Genome sequence of Lactobacillus crispatus ST1. J Bacteriol (2010) 0.91
Identifying functional gene sets from hierarchically clustered expression data: map of abiotic stress regulated genes in Arabidopsis thaliana. Nucleic Acids Res (2006) 0.91
Upregulation of the neuron-specific K+/Cl- cotransporter expression by transcription factor early growth response 4. J Neurosci (2006) 0.91
SANS: high-throughput retrieval of protein sequences allowing 50% mismatches. Bioinformatics (2012) 0.89
Evaluation of different domain-based methods in protein interaction prediction. Biochem Biophys Res Commun (2009) 0.88
POCO: discovery of regulatory patterns from promoters of oppositely expressed gene sets. Nucleic Acids Res (2005) 0.87
Impaired behavioural flexibility and memory in mice lacking GDNF family receptor alpha2. Eur J Neurosci (2004) 0.87
Oligomerization of Uukuniemi virus nucleocapsid protein. Virol J (2010) 0.87
GOParGenPy: a high throughput method to generate gene ontology data matrices. BMC Bioinformatics (2013) 0.87
A theoretical model for the regulation of Sex-lethal, a gene that controls sex determination and dosage compensation in Drosophila melanogaster. Genetics (2003) 0.87
Comparative genomics of Lactobacillus crispatus suggests novel mechanisms for the competitive exclusion of Gardnerella vaginalis. BMC Genomics (2014) 0.86
Hyperpolarizing GABAergic transmission requires the KCC2 C-terminal ISO domain. J Neurosci (2012) 0.85
Distribution of neuronal KCC2a and KCC2b isoforms in mouse CNS. J Comp Neurol (2014) 0.85
GDNF family ligands activate multiple events during axonal growth in mature sensory neurons. Mol Cell Neurosci (2004) 0.84
GDNF family signalling in exocrine tissues: distinct roles for GDNF and neurturin in parasympathetic neuron development. Adv Exp Med Biol (2002) 0.84
Ablation of persephin receptor glial cell line-derived neurotrophic factor family receptor alpha4 impairs thyroid calcitonin production in young mice. Endocrinology (2006) 0.83
Sympathetic cholinergic target innervation requires GDNF family receptor GFR alpha 2. Mol Cell Neurosci (2004) 0.83
Role of upstream stimulating factors in the transcriptional regulation of the neuron-specific K-Cl cotransporter KCC2. Brain Res (2008) 0.82
Altered synaptic dynamics and hippocampal excitability but normal long-term plasticity in mice lacking hyperpolarizing GABA A receptor-mediated inhibition in CA1 pyramidal neurons. J Neurophysiol (2008) 0.82
Neurturin evokes MAPK-dependent upregulation of Egr4 and KCC2 in developing neurons. Neural Plast (2011) 0.82
LOCP--locating pilus operons in gram-positive bacteria. Bioinformatics (2009) 0.82
A novel method for assigning functional linkages to proteins using enhanced phylogenetic trees. Bioinformatics (2010) 0.80
Neuronal K+/Cl- co-transporter (KCC2) transgenes lacking neurone restrictive silencer element recapitulate CNS neurone-specific expression and developmental up-regulation of endogenous KCC2 gene. J Neurochem (2005) 0.80
KCC2-deficient mice show reduced sensitivity to diazepam, but normal alcohol-induced motor impairment, gaboxadol-induced sedation, and neurosteroid-induced hypnosis. Neuropsychopharmacology (2006) 0.79
LRRTM3 is dispensable for amyloid-β production in mice. J Alzheimers Dis (2012) 0.79
Mutational analysis of positively charged amino acid residues of Uukuniemi phlebovirus nucleocapsid protein. Virus Res (2012) 0.78
Genome sequence of Pectobacterium sp. strain SCC3193. J Bacteriol (2012) 0.78
Comprehensive comparison of graph based multiple protein sequence alignment strategies. BMC Bioinformatics (2012) 0.77
Adhesive polypeptides of Staphylococcus aureus identified using a novel secretion library technique in Escherichia coli. BMC Microbiol (2011) 0.77
Increased apoptosis of parasympathetic but not enteric neurons in mice lacking GFRalpha2. Dev Biol (2007) 0.77
Genomics and Proteomics Provide New Insight into the Commensal and Pathogenic Lifestyles of Bovine- and Human-Associated Staphylococcus epidermidis Strains. J Proteome Res (2014) 0.76
Mismatch repair analysis of inherited MSH2 and/or MSH6 variation pairs found in cancer patients. Hum Mutat (2012) 0.76
Lack of cholinergic innervation in gastric mucosa does not affect gastrin secretion or basal acid output in neurturin receptor GFRα2 deficient mice. J Physiol (2013) 0.75
Inferring the physical connectivity of complex networks from their functional dynamics. BMC Syst Biol (2010) 0.75
From sequences to a functional unit. Physiol Genomics (2006) 0.75