Published in Bioinformatics on December 08, 2006
'Glocal' robustness analysis and model discrimination for circadian oscillators. PLoS Comput Biol (2009) 1.05
Systems interface biology. J R Soc Interface (2006) 1.01
Sensitivity Measures for Oscillating Systems: Application to Mammalian Circadian Gene Network. IEEE Trans Automat Contr (2008) 0.98
Robustness from flexibility in the fungal circadian clock. BMC Syst Biol (2010) 0.91
Circadian phase resetting via single and multiple control targets. PLoS Comput Biol (2008) 0.87
Identifying fragilities in biochemical networks: robust performance analysis of Fas signaling-induced apoptosis. Biophys J (2008) 0.86
Mathematical identification of critical reactions in the interlocked feedback model. PLoS One (2007) 0.85
Consistent robustness analysis (CRA) identifies biologically relevant properties of regulatory network models. PLoS One (2010) 0.83
Modeling the Drosophila melanogaster circadian oscillator via phase optimization. J Biol Rhythms (2008) 0.81
What can we learn from global sensitivity analysis of biochemical systems? PLoS One (2013) 0.79
Robustness portraits of diverse biological networks conserved despite order-of-magnitude parameter uncertainty. Bioinformatics (2011) 0.78
Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk. BMC Syst Biol (2010) 0.78
Architecture-dependent robustness and bistability in a class of genetic circuits. Biophys J (2010) 0.78
Amplitude distribution of stochastic oscillations in biochemical networks due to intrinsic noise. PMC Biophys (2009) 0.77
Feedback, Mass Conservation and Reaction Kinetics Impact the Robustness of Cellular Oscillations. PLoS Comput Biol (2016) 0.75
Robustness of cellular functions. Cell (2004) 6.65
Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell (2007) 4.87
A tunable synthetic mammalian oscillator. Nature (2009) 4.33
Fully integrated artificial pancreas in type 1 diabetes: modular closed-loop glucose control maintains near normoglycemia. Diabetes (2012) 3.40
Dynamic flux balance analysis of diauxic growth in Escherichia coli. Biophys J (2002) 3.10
Two approaches for metabolic pathway analysis? Trends Biotechnol (2003) 2.87
FluxAnalyzer: exploring structure, pathways, and flux distributions in metabolic networks on interactive flux maps. Bioinformatics (2003) 2.49
A novel computational model of the circadian clock in Arabidopsis that incorporates PRR7 and PRR9. Mol Syst Biol (2006) 2.48
Global network reorganization during dynamic adaptations of Bacillus subtilis metabolism. Science (2012) 2.38
Robustness properties of circadian clock architectures. Proc Natl Acad Sci U S A (2004) 2.31
Detection of a meal using continuous glucose monitoring: implications for an artificial beta-cell. Diabetes Care (2007) 2.30
Feasibility of outpatient fully integrated closed-loop control: first studies of wearable artificial pancreas. Diabetes Care (2013) 2.26
Prevention of nocturnal hypoglycemia using predictive alarm algorithms and insulin pump suspension. Diabetes Care (2010) 2.18
Importance of input perturbations and stochastic gene expression in the reverse engineering of genetic regulatory networks: insights from an identifiability analysis of an in silico network. Genome Res (2003) 2.09
A benchmark for methods in reverse engineering and model discrimination: problem formulation and solutions. Genome Res (2004) 2.06
Safety constraints in an artificial pancreatic beta cell: an implementation of model predictive control with insulin on board. J Diabetes Sci Technol (2009) 2.06
Bolus calculator: a review of four "smart" insulin pumps. Diabetes Technol Ther (2008) 1.96
Identification of small molecule activators of cryptochrome. Science (2012) 1.95
Large-scale computation of elementary flux modes with bit pattern trees. Bioinformatics (2008) 1.95
Combinatorial complexity of pathway analysis in metabolic networks. Mol Biol Rep (2002) 1.92
Ensemble modeling for analysis of cell signaling dynamics. Nat Biotechnol (2007) 1.84
Iterative approach to model identification of biological networks. BMC Bioinformatics (2005) 1.80
Synthetic two-way communication between mammalian cells. Nat Biotechnol (2012) 1.78
Sensitivity analysis of discrete stochastic systems. Biophys J (2005) 1.70
Clinical evaluation of a personalized artificial pancreas. Diabetes Care (2012) 1.69
Real-Time hypoglycemia prediction suite using continuous glucose monitoring: a safety net for the artificial pancreas. Diabetes Care (2010) 1.66
Self-sufficient control of urate homeostasis in mice by a synthetic circuit. Nat Biotechnol (2010) 1.64
Model-based blood glucose control for Type 1 diabetes via parametric programming. IEEE Trans Biomed Eng (2006) 1.63
Zone model predictive control: a strategy to minimize hyper- and hypoglycemic events. J Diabetes Sci Technol (2010) 1.62
A synthetic time-delay circuit in mammalian cells and mice. Proc Natl Acad Sci U S A (2007) 1.59
Pilot studies of wearable outpatient artificial pancreas in type 1 diabetes. Diabetes Care (2012) 1.57
Control to range for diabetes: functionality and modular architecture. J Diabetes Sci Technol (2009) 1.55
A molecular model for intercellular synchronization in the mammalian circadian clock. Biophys J (2007) 1.54
A model of the cell-autonomous mammalian circadian clock. Proc Natl Acad Sci U S A (2009) 1.46
Run-to-run control of blood glucose concentrations for people with Type 1 diabetes mellitus. IEEE Trans Biomed Eng (2006) 1.39
Prandial insulin dosing using run-to-run control: application of clinical data and medical expertise to define a suitable performance metric. Diabetes Care (2007) 1.36
A Run-to-Run Control Strategy to Adjust Basal Insulin Infusion Rates in Type 1 Diabetes. J Process Control (2008) 1.31
Computational design tools for synthetic biology. Curr Opin Biotechnol (2009) 1.26
In silico evaluation platform for artificial pancreatic beta-cell development--a dynamic simulator for closed-loop control with hardware-in-the-loop. Diabetes Technol Ther (2009) 1.24
Control-relevant models for glucose control using a priori patient characteristics. IEEE Trans Biomed Eng (2011) 1.23
Counter-intuitive stochastic behavior of simple gene circuits with negative feedback. Biophys J (2010) 1.22
Subnetwork analysis reveals dynamic features of complex (bio)chemical networks. Proc Natl Acad Sci U S A (2007) 1.21
Enhanced 911/global position system wizard: a telemedicine application for the prevention of severe hypoglycemia--monitor, alert, and locate. J Diabetes Sci Technol (2009) 1.20
In silico preclinical trials: methodology and engineering guide to closed-loop control in type 1 diabetes mellitus. J Diabetes Sci Technol (2009) 1.19
A neuropeptide speeds circadian entrainment by reducing intercellular synchrony. Proc Natl Acad Sci U S A (2013) 1.19
Design of the health monitoring system for the artificial pancreas: low glucose prediction module. J Diabetes Sci Technol (2012) 1.14
Genome-scale metabolic networks. Wiley Interdiscip Rev Syst Biol Med (2010) 1.11
Transcriptional regulation is insufficient to explain substrate-induced flux changes in Bacillus subtilis. Mol Syst Biol (2013) 1.11
Systems analysis of cellular networks under uncertainty. FEBS Lett (2009) 1.09
Quest for the artificial pancreas: combining technology with treatment. IEEE Eng Med Biol Mag (2010) 1.09
Closed-loop control and advisory mode evaluation of an artificial pancreatic Beta cell: use of proportional-integral-derivative equivalent model-based controllers. J Diabetes Sci Technol (2008) 1.09
Glucose estimation and prediction through meal responses using ambulatory subject data for advisory mode model predictive control. J Diabetes Sci Technol (2007) 1.07
Automatic design of digital synthetic gene circuits. PLoS Comput Biol (2011) 1.06
Energy-efficient pulse-coupled synchronization strategy design for wireless sensor networks through reduced idle listening. IEEE Trans Signal Process (2012) 1.06
Isochron-based phase response analysis of circadian rhythms. Biophys J (2006) 1.06
Use of continuous glucose monitoring to estimate insulin requirements in patients with type 1 diabetes mellitus during a short course of prednisone. J Diabetes Sci Technol (2008) 1.05
Wavelet measurement suggests cause of period instability in mammalian circadian neurons. J Biol Rhythms (2011) 1.04
Closed-loop control of artificial pancreatic Beta -cell in type 1 diabetes mellitus using model predictive iterative learning control. IEEE Trans Biomed Eng (2009) 1.03
Modeling cortisol dynamics in the neuro-endocrine axis distinguishes normal, depression, and post-traumatic stress disorder (PTSD) in humans. PLoS Comput Biol (2012) 1.03
Calculating the insulin to carbohydrate ratio using the hyperinsulinaemic-euglycaemic clamp-a novel use for a proven technique. Diabetes Metab Res Rev (2007) 1.02
Coordinated basal-bolus infusion for tighter postprandial glucose control in insulin pump therapy. J Diabetes Sci Technol (2009) 1.02
Experimental evaluation of a recursive model identification technique for type 1 diabetes. J Diabetes Sci Technol (2009) 1.02
Systems interface biology. J R Soc Interface (2006) 1.01
Decreased protein expression and intermittent recoveries in BiP levels result from cellular stress during heterologous protein expression in Saccharomyces cerevisiae. Biotechnol Prog (2002) 1.01
Proposed clinical application for tuning fuzzy logic controller of artificial pancreas utilizing a personalization factor. J Diabetes Sci Technol (2010) 1.00
Optimal phase response functions for fast pulse-coupled synchronization in wireless sensor networks. IEEE Trans Signal Process (2012) 0.99
Multicenter closed-loop insulin delivery study points to challenges for keeping blood glucose in a safe range by a control algorithm in adults and adolescents with type 1 diabetes from various sites. Diabetes Technol Ther (2014) 0.99
Synchrony and entrainment properties of robust circadian oscillators. J R Soc Interface (2008) 0.99
Sensitivity Measures for Oscillating Systems: Application to Mammalian Circadian Gene Network. IEEE Trans Automat Contr (2008) 0.98
Clinical evaluation of an automated artificial pancreas using zone-model predictive control and health monitoring system. Diabetes Technol Ther (2014) 0.98
Dynamic energy budgets in syntrophic symbiotic relationships between heterotrophic hosts and photoautotrophic symbionts. J Theor Biol (2009) 0.97
System-level insights into yeast metabolism by thermodynamic analysis of elementary flux modes. PLoS Comput Biol (2012) 0.97
Weakly circadian cells improve resynchrony. PLoS Comput Biol (2012) 0.97
Collagen cross-linking using rose bengal and green light to increase corneal stiffness. Invest Ophthalmol Vis Sci (2013) 0.96
Modeling the effects of subcutaneous insulin administration and carbohydrate consumption on blood glucose. J Diabetes Sci Technol (2010) 0.95
A novel adaptive basal therapy based on the value and rate of change of blood glucose. J Diabetes Sci Technol (2009) 0.95
Analysis of unfolded protein response during single-chain antibody expression in Saccaromyces cerevisiae reveals different roles for BiP and PDI in folding. Metab Eng (2005) 0.94
Multicenter closed-loop/hybrid meal bolus insulin delivery with type 1 diabetes. Diabetes Technol Ther (2014) 0.93
Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock. Proc Natl Acad Sci U S A (2014) 0.91
On influences of global and local cues on the rate of synchronization of oscillator networks. Automatica (Oxf) (2011) 0.90
Core modular blood and brain biomarkers in social defeat mouse model for post traumatic stress disorder. BMC Syst Biol (2013) 0.90
Near-optimal experimental design for model selection in systems biology. Bioinformatics (2013) 0.90
Bridging the gaps in systems biology. Mol Genet Genomics (2014) 0.90
Clinical update on optimal prandial insulin dosing using a refined run-to-run control algorithm. J Diabetes Sci Technol (2009) 0.90
Periodic-zone model predictive control for diurnal closed-loop operation of an artificial pancreas. J Diabetes Sci Technol (2013) 0.90
Predicting subcutaneous glucose concentration using a latent-variable-based statistical method for type 1 diabetes mellitus. J Diabetes Sci Technol (2012) 0.89
Precise regulation of gene expression dynamics favors complex promoter architectures. PLoS Comput Biol (2009) 0.88
Velocity response curves support the role of continuous entrainment in circadian clocks. J Biol Rhythms (2010) 0.88
The galactose switch in Kluyveromyces lactis depends on nuclear competition between Gal4 and Gal1 for Gal80 binding. J Biol Chem (2006) 0.87
Multi-objective blood glucose control for type 1 diabetes. Med Biol Eng Comput (2009) 0.87
Modular, rule-based modeling for the design of eukaryotic synthetic gene circuits. BMC Syst Biol (2013) 0.87
Circadian phase resetting via single and multiple control targets. PLoS Comput Biol (2008) 0.87
Identifying fragilities in biochemical networks: robust performance analysis of Fas signaling-induced apoptosis. Biophys J (2008) 0.86
Artificial pancreas (AP) clinical trial participants' acceptance of future AP technology. Diabetes Technol Ther (2014) 0.85
Continuous-time identification of gene expression models. OMICS (2003) 0.85
Phase sensitivity analysis of circadian rhythm entrainment. J Biol Rhythms (2007) 0.85
Oscillator model reduction preserving the phase response: application to the circadian clock. Biophys J (2008) 0.84
Core module biomarker identification with network exploration for breast cancer metastasis. BMC Bioinformatics (2012) 0.84
Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology. PLoS Comput Biol (2010) 0.82