Published in Proc Natl Acad Sci U S A on June 19, 2009
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Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis. J Biol Rhythms (2007) 1.35
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FKF1 and GIGANTEA complex formation is required for day-length measurement in Arabidopsis. Science (2007) 4.64
Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression. Curr Biol (2004) 4.49
A functional genomics approach reveals CHE as a component of the Arabidopsis circadian clock. Science (2009) 4.49
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Melanopsin (Opn4) requirement for normal light-induced circadian phase shifting. Science (2002) 4.24
Molecular basis of seasonal time measurement in Arabidopsis. Nature (2002) 4.24
Melanopsin is required for non-image-forming photic responses in blind mice. Science (2003) 4.22
Genome-wide single-nucleotide polymorphism analysis defines haplotype patterns in mouse. Proc Natl Acad Sci U S A (2003) 3.93
Targeted degradation of TOC1 by ZTL modulates circadian function in Arabidopsis thaliana. Nature (2003) 3.56
FKF1 F-box protein mediates cyclic degradation of a repressor of CONSTANS in Arabidopsis. Science (2005) 3.56
Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia. Nature (2011) 3.51
FKF1 is essential for photoperiodic-specific light signalling in Arabidopsis. Nature (2003) 3.47
Fully integrated artificial pancreas in type 1 diabetes: modular closed-loop glucose control maintains near normoglycemia. Diabetes (2012) 3.40
Overlapping and distinct roles of PRR7 and PRR9 in the Arabidopsis circadian clock. Curr Biol (2005) 3.36
Network discovery pipeline elucidates conserved time-of-day-specific cis-regulatory modules. PLoS Genet (2008) 3.35
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A genome-wide RNAi screen for modifiers of the circadian clock in human cells. Cell (2009) 3.27
Dynamic flux balance analysis of diauxic growth in Escherichia coli. Biophys J (2002) 3.10
The ELF4-ELF3-LUX complex links the circadian clock to diurnal control of hypocotyl growth. Nature (2011) 3.09
Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms. PLoS Genet (2008) 3.07
LUX ARRHYTHMO encodes a Myb domain protein essential for circadian rhythms. Proc Natl Acad Sci U S A (2005) 3.04
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Dual role of TOC1 in the control of circadian and photomorphogenic responses in Arabidopsis. Plant Cell (2003) 2.86
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Delay in feedback repression by cryptochrome 1 is required for circadian clock function. Cell (2011) 2.71
Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nat Med (2010) 2.65
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A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta. Proc Natl Acad Sci U S A (2008) 2.39
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Detection of a meal using continuous glucose monitoring: implications for an artificial beta-cell. Diabetes Care (2007) 2.30
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Living by the calendar: how plants know when to flower. Nat Rev Mol Cell Biol (2003) 2.21
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A morning-specific phytohormone gene expression program underlying rhythmic plant growth. PLoS Biol (2008) 2.12
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Rapid array mapping of circadian clock and developmental mutations in Arabidopsis. Plant Physiol (2005) 2.07
A benchmark for methods in reverse engineering and model discrimination: problem formulation and solutions. Genome Res (2004) 2.06
Safety constraints in an artificial pancreatic beta cell: an implementation of model predictive control with insulin on board. J Diabetes Sci Technol (2009) 2.06
Universality and flexibility in gene expression from bacteria to human. Proc Natl Acad Sci U S A (2004) 2.03
PRR3 Is a vascular regulator of TOC1 stability in the Arabidopsis circadian clock. Plant Cell (2007) 1.97
Bolus calculator: a review of four "smart" insulin pumps. Diabetes Technol Ther (2008) 1.96
Identification of small molecule activators of cryptochrome. Science (2012) 1.95
Emergence of noise-induced oscillations in the central circadian pacemaker. PLoS Biol (2010) 1.94
A genomic analysis of the shade avoidance response in Arabidopsis. Plant Physiol (2003) 1.91
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Linking photoreceptor excitation to changes in plant architecture. Genes Dev (2012) 1.80
LUX ARRHYTHMO encodes a nighttime repressor of circadian gene expression in the Arabidopsis core clock. Curr Biol (2011) 1.78
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A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration. Proc Natl Acad Sci U S A (2009) 1.74
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Real-Time hypoglycemia prediction suite using continuous glucose monitoring: a safety net for the artificial pancreas. Diabetes Care (2010) 1.66
GIGANTEA directly activates Flowering Locus T in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2011) 1.66
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Model-based blood glucose control for Type 1 diabetes via parametric programming. IEEE Trans Biomed Eng (2006) 1.63
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F-box proteins FKF1 and LKP2 act in concert with ZEITLUPE to control Arabidopsis clock progression. Plant Cell (2010) 1.48
CIRCADIAN CLOCK-ASSOCIATED 1 regulates ROS homeostasis and oxidative stress responses. Proc Natl Acad Sci U S A (2012) 1.44
Circadian regulation of ATP release in astrocytes. J Neurosci (2011) 1.41
Reciprocity between phase shifts and amplitude changes in the mammalian circadian clock. Proc Natl Acad Sci U S A (2007) 1.41
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Expression of the circadian clock gene Period2 in the hippocampus: possible implications for synaptic plasticity and learned behaviour. ASN Neuro (2009) 1.26
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