Michael V Norgard

Author PubWeight™ 66.98‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete. Proc Natl Acad Sci U S A 2002 3.82
2 OspC facilitates Borrelia burgdorferi invasion of Ixodes scapularis salivary glands. J Clin Invest 2004 3.38
3 Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J Exp Med 2004 3.02
4 The Lyme disease agent exploits a tick protein to infect the mammalian host. Nature 2005 2.82
5 The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi. Proc Natl Acad Sci U S A 2003 2.31
6 Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. Nat Med 2003 2.08
7 bptA (bbe16) is essential for the persistence of the Lyme disease spirochete, Borrelia burgdorferi, in its natural tick vector. Proc Natl Acad Sci U S A 2005 1.66
8 Characterization of Francisella tularensis outer membrane proteins. J Bacteriol 2006 1.59
9 Assessment of decorin-binding protein A to the infectivity of Borrelia burgdorferi in the murine models of needle and tick infection. BMC Microbiol 2008 1.51
10 Transcriptional interplay among the regulators Rrp2, RpoN and RpoS in Borrelia burgdorferi. Microbiology 2008 1.46
11 Analysis of the ospC regulatory element controlled by the RpoN-RpoS regulatory pathway in Borrelia burgdorferi. J Bacteriol 2005 1.44
12 BosR (BB0647) governs virulence expression in Borrelia burgdorferi. Mol Microbiol 2009 1.42
13 Determination of protein complex stoichiometry through multisignal sedimentation velocity experiments. Anal Biochem 2010 1.36
14 Central nervous system infection in congenital syphilis. N Engl J Med 2002 1.35
15 Evidence that RpoS (sigmaS) in Borrelia burgdorferi is controlled directly by RpoN (sigma54/sigmaN). J Bacteriol 2006 1.34
16 Expression of a luxS gene is not required for Borrelia burgdorferi infection of mice via needle inoculation. Infect Immun 2003 1.32
17 Native outer membrane proteins protect mice against pulmonary challenge with virulent type A Francisella tularensis. Infect Immun 2008 1.31
18 The effect of progesterone levels and pregnancy on HIV-1 coreceptor expression. Reprod Sci 2009 1.28
19 BosR (BB0647) controls the RpoN-RpoS regulatory pathway and virulence expression in Borrelia burgdorferi by a novel DNA-binding mechanism. PLoS Pathog 2011 1.22
20 Regulation of expression of the paralogous Mlp family in Borrelia burgdorferi. Infect Immun 2003 1.21
21 Characterization of fig operon mutants of Francisella novicida U112. FEMS Microbiol Lett 2008 1.21
22 The crystal structure of Zn(II)-free Treponema pallidum TroA, a periplasmic metal-binding protein, reveals a closed conformation. J Bacteriol 2002 1.21
23 Adaptation of a luciferase gene reporter and lac expression system to Borrelia burgdorferi. Appl Environ Microbiol 2007 1.16
24 A manganese transporter, BB0219 (BmtA), is required for virulence by the Lyme disease spirochete, Borrelia burgdorferi. Proc Natl Acad Sci U S A 2009 1.11
25 Crystal structure of the Tp34 (TP0971) lipoprotein of treponema pallidum: implications of its metal-bound state and affinity for human lactoferrin. J Biol Chem 2006 1.10
26 The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum. J Biol Chem 2006 1.09
27 Cyclic di-GMP is essential for the survival of the lyme disease spirochete in ticks. PLoS Pathog 2011 1.08
28 Effect of genital ulcer disease on HIV-1 coreceptor expression in the female genital tract. J Infect Dis 2007 1.06
29 Rrp2, a sigma54-dependent transcriptional activator of Borrelia burgdorferi, activates rpoS in an enhancer-independent manner. J Bacteriol 2009 1.06
30 Crystal structure of the 47-kDa lipoprotein of Treponema pallidum reveals a novel penicillin-binding protein. J Biol Chem 2002 0.98
31 The luxS gene is not required for Borrelia burgdorferi tick colonization, transmission to a mammalian host, or induction of disease. Infect Immun 2004 0.97
32 Activation of the RpoN-RpoS regulatory pathway during the enzootic life cycle of Borrelia burgdorferi. BMC Microbiol 2012 0.97
33 IglE is an outer membrane-associated lipoprotein essential for intracellular survival and murine virulence of type A Francisella tularensis. Infect Immun 2013 0.96
34 Structural and biochemical basis for polyamine binding to the Tp0655 lipoprotein of Treponema pallidum: putative role for Tp0655 (TpPotD) as a polyamine receptor. J Mol Biol 2007 0.95
35 Structural, bioinformatic, and in vivo analyses of two Treponema pallidum lipoproteins reveal a unique TRAP transporter. J Mol Biol 2012 0.94
36 Differential expression of a putative CarD-like transcriptional regulator, LtpA, in Borrelia burgdorferi. Infect Immun 2008 0.93
37 Abrogation of ospAB constitutively activates the Rrp2-RpoN-RpoS pathway (sigmaN-sigmaS cascade) in Borrelia burgdorferi. Mol Microbiol 2008 0.93
38 Evidence for an ABC-type riboflavin transporter system in pathogenic spirochetes. MBio 2013 0.92
39 Structural evidence that the 32-kilodalton lipoprotein (Tp32) of Treponema pallidum is an L-methionine-binding protein. J Biol Chem 2004 0.90
40 Structural and thermodynamic characterization of the interaction between two periplasmic Treponema pallidum lipoproteins that are components of a TPR-protein-associated TRAP transporter (TPAT). J Mol Biol 2012 0.87
41 Invariant NKT cell development requires a full complement of functional CD3 zeta immunoreceptor tyrosine-based activation motifs. J Immunol 2010 0.86
42 The TP0796 lipoprotein of Treponema pallidum is a bimetal-dependent FAD pyrophosphatase with a potential role in flavin homeostasis. J Biol Chem 2013 0.84
43 The Tp38 (TpMglB-2) lipoprotein binds glucose in a manner consistent with receptor function in Treponema pallidum. J Bacteriol 2004 0.84
44 Biophysical and bioinformatic analyses implicate the Treponema pallidum Tp34 lipoprotein (Tp0971) in transition metal homeostasis. J Bacteriol 2012 0.83
45 Analysis of the dbpBA upstream regulatory region controlled by RpoS in Borrelia burgdorferi. J Bacteriol 2010 0.83
46 Sequence, biophysical, and structural analyses of the PstS lipoprotein (BB0215) from Borrelia burgdorferi reveal a likely binding component of an ABC-type phosphate transporter. Protein Sci 2013 0.82
47 CsrA (BB0184) is not involved in activation of the RpoN-RpoS regulatory pathway in Borrelia burgdorferi. Infect Immun 2014 0.81
48 Method for the isolation of Francisella tularensis outer membranes. J Vis Exp 2010 0.81
49 Assessment of cell-surface exposure and vaccinogenic potentials of Treponema pallidum candidate outer membrane proteins. Microbes Infect 2007 0.80
50 Insights into the potential function and membrane organization of the TP0435 (Tp17) lipoprotein from Treponema pallidum derived from structural and biophysical analyses. Protein Sci 2014 0.78
51 Purification, crystallization and preliminary X-ray analysis of TP0435 (Tp17) from the syphilis spirochete Treponema pallidum. Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 0.78
52 Identification of a core sequence for the binding of BosR to the rpoS promoter region in Borrelia burgdorferi. Microbiology 2015 0.77
53 Identification of a core sequence for the binding of BosR to the rpoS promoter region in Borrelia burgdorferi. Microbiology 2014 0.77