Messing with bacterial quorum sensing.

Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev (2008) 17.77

Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action. J Am Chem Soc (2007) 1.86

Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria. Chem Soc Rev (2008) 1.62

Genomic analysis reveals versatile organisms for quorum quenching enzymes: acyl-homoserine lactone-acylase and -lactonase. Open Microbiol J (2011) 1.49

Inhibitors of pathogen intercellular signals as selective anti-infective compounds. PLoS Pathog (2007) 1.38

Inhibition of quorum sensing-controlled virulence factor production in Pseudomonas aeruginosa PAO1 by Ayurveda spice clove (Syzygium aromaticum) bud extract. Sensors (Basel) (2012) 1.37

Identification of catechin as one of the flavonoids from Combretum albiflorum bark extract that reduces the production of quorum-sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1. Appl Environ Microbiol (2009) 1.33

Peptide pheromone signaling in Streptococcus and Enterococcus. FEMS Microbiol Rev (2013) 1.25

Unraveling microbial interactions in food fermentations: from classical to genomics approaches. Appl Environ Microbiol (2008) 1.25

Plant-derived natural products as sources of anti-quorum sensing compounds. Sensors (Basel) (2013) 1.13

Genomes and virulence factors of novel bacterial pathogens causing bleaching disease in the marine red alga Delisea pulchra. PLoS One (2011) 1.11

Impact of interspecific interactions on antimicrobial activity among soil bacteria. Front Microbiol (2014) 1.08

Biofouling of water treatment membranes: a review of the underlying causes, monitoring techniques and control measures. Membranes (Basel) (2012) 1.03

Two dissimilar N-acyl-homoserine lactone acylases of Pseudomonas syringae influence colony and biofilm morphology. Appl Environ Microbiol (2008) 1.01

The GtaR protein negatively regulates transcription of the gtaRI operon and modulates gene transfer agent (RcGTA) expression in Rhodobacter capsulatus. Mol Microbiol (2012) 0.96

Predator-prey chemical warfare determines the expression of biocontrol genes by rhizosphere-associated Pseudomonas fluorescens. Appl Environ Microbiol (2010) 0.95

Quorum sensing primes the oxidative stress response in the insect endosymbiont, Sodalis glossinidius. PLoS One (2008) 0.95

Chemorepulsion from the Quorum Signal Autoinducer-2 Promotes Helicobacter pylori Biofilm Dispersal. MBio (2015) 0.94

Non-antibiotic quorum sensing inhibitors acting against N-acyl homoserine lactone synthase as druggable target. Sci Rep (2014) 0.91

Assembling the components of the quorum sensing pathway in African trypanosomes. Mol Microbiol (2015) 0.91

Repression of tropolone production and induction of a Burkholderia plantarii pseudo-biofilm by carot-4-en-9,10-diol, a cell-to-cell signaling disrupter produced by Trichoderma virens. PLoS One (2013) 0.90

Rapid screening of quorum-sensing signal N-acyl homoserine lactones by an in vitro cell-free assay. Appl Environ Microbiol (2008) 0.87

New and unexpected insights into the modulation of LuxR-type quorum sensing by cyclic dipeptides. ACS Chem Biol (2009) 0.87

Future research trends in the major chemical language of bacteria. HFSP J (2009) 0.87

Plant and pathogen nutrient acquisition strategies. Front Plant Sci (2015) 0.86

Antimicrobial and anti-Quorum Sensing activities of selected medicinal plants of Ethiopia: Implication for development of potent antimicrobial agents. BMC Microbiol (2016) 0.86

The genus Thermotoga: recent developments. Environ Technol (2010) 0.86

A walk into the LuxR regulators of Actinobacteria: phylogenomic distribution and functional diversity. PLoS One (2012) 0.84

Biofilm formation, host-cell adherence, and virulence genes regulation of Streptococcus suis in response to autoinducer-2 signaling. Curr Microbiol (2013) 0.83

Quorum sensing signal production and microbial interactions in a polymicrobial disease of corals and the coral surface mucopolysaccharide layer. PLoS One (2014) 0.82

Quorum-sensing regulation of a capsular polysaccharide receptor for the Rhodobacter capsulatus gene transfer agent (RcGTA). Mol Microbiol (2013) 0.82

Quorum sensing dependent phenotypes and their molecular mechanisms in Campylobacterales. Eur J Microbiol Immunol (Bp) (2012) 0.81

Small molecule inhibitors of AI-2 signaling in bacteria: state-of-the-art and future perspectives for anti-quorum sensing agents. Int J Mol Sci (2013) 0.81

Kinetic model for signal binding to the Quorum sensing regulator LasR. Int J Mol Sci (2013) 0.79

Attenuation of Edwardsiella tarda virulence by small peptides that interfere with LuxS/autoinducer type 2 quorum sensing. Appl Environ Microbiol (2009) 0.79

Inhibiting N-acyl-homoserine lactone synthesis and quenching Pseudomonas quinolone quorum sensing to attenuate virulence. Front Microbiol (2015) 0.79

Cytotoxicity of cyclodipeptides from Pseudomonas aeruginosa PAO1 leads to apoptosis in human cancer cell lines. Biomed Res Int (2015) 0.79

Crystal Structure and Identification of Two Key Amino Acids Involved in AI-2 Production and Biofilm Formation in Streptococcus suis LuxS. PLoS One (2015) 0.78

Repression of the locus of the enterocyte effacement-encoded regulator of gene transcription of Escherichia coli O157:H7 by Lactobacillus reuteri culture supernatants is LuxS and strain dependent. Appl Environ Microbiol (2008) 0.78

Single cell time-resolved quorum responses reveal dependence on cell density and configuration. J Biol Chem (2011) 0.78

Overexpression of luxS cannot increase autoinducer-2 production, only affect the growth and biofilm formation in Streptococcus suis. ScientificWorldJournal (2013) 0.78

Molecular insights into quorum sensing in Acidithiobacillus ferrooxidans bacteria via molecular modelling of the transcriptional regulator AfeR and of the binding mode of long-chain acyl homoserine lactones. J Mol Model (2008) 0.77

Type 2 quorum sensing monitoring, inhibition and biofilm formation in marine microrganisms. Curr Microbiol (2013) 0.77

Cyclo(Phe-Pro) produced by the human pathogen Vibrio vulnificus inhibits host innate immune responses through the NF-κB pathway. Infect Immun (2015) 0.77

Microbial biofilm as a smart material. Sensors (Basel) (2015) 0.76

Pseudomonas aeruginosa Lifestyle: A Paradigm for Adaptation, Survival, and Persistence. Front Cell Infect Microbiol (2017) 0.76

Cranberry-derived proanthocyanidins impair virulence and inhibit quorum sensing of Pseudomonas aeruginosa. Sci Rep (2016) 0.76

Nonphotosynthetic pigments as potential biosignatures. Astrobiology (2015) 0.76

Marine Microorganisms: perspectives for getting involved in cellulosic ethanol. AMB Express (2012) 0.76

Efficacy of the Quorum Sensing Inhibitor FS10 Alone and in Combination with Tigecycline in an Animal Model of Staphylococcal Infected Wound. PLoS One (2016) 0.76

Selection of the N-Acylhomoserine Lactone-Degrading Bacterium Alteromonas stellipolaris PQQ-42 and of Its Potential for Biocontrol in Aquaculture. Front Microbiol (2016) 0.75

Correlation between group behavior and quorum sensing in Pseudomonas aeruginosa isolated from patients with hospital-acquired pneumonia. J Thorac Dis (2014) 0.75

Emergence or self-organization?: Look to the soil population. Commun Integr Biol (2011) 0.75

Genome sequence of Enterobacter sp. ST3, a quorum sensing bacterium associated with marine dinoflagellate. Genom Data (2016) 0.75

Analysis of the antibacterial effect of an Edwardsiella tarda LuxS inhibitor. Springerplus (2016) 0.75

Anti-Quorum Sensing Activity of Substances Isolated from Wild Berry Associated Bacteria. Avicenna J Med Biotechnol (2017) 0.75

Broad Spectrum Anti-Quorum Sensing Activity of Tannin-Rich Crude Extracts of Indian Medicinal Plants. Scientifica (Cairo) (2016) 0.75

Scaffold of Selenium Nanovectors and Honey Phytochemicals for Inhibition of Pseudomonas aeruginosa Quorum Sensing and Biofilm Formation. Front Cell Infect Microbiol (2017) 0.75

The Master Quorum-Sensing Regulator OpaR is Activated Indirectly by H-NS in Vibrio parahaemolyticus. Curr Microbiol (2016) 0.75

Metabolic Fingerprints from the Human Oral Microbiome Reveal a Vast Knowledge Gap of Secreted Small Peptidic Molecules. mSystems (2017) 0.75

A Single Regulator Mediates Strategic Switching between Attachment/Spread and Growth/Virulence in the Plant Pathogen Ralstonia solanacearum. MBio (2017) 0.75

Bacterial bioluminescence: isolation and genetic analysis of functions from Vibrio fischeri. Cell (1983) 12.68

Structural identification of autoinducer of Photobacterium fischeri luciferase. Biochemistry (1981) 11.48

Cellular control of the synthesis and activity of the bacterial luminescent system. J Bacteriol (1970) 10.35

Identification of genes and gene products necessary for bacterial bioluminescence. Proc Natl Acad Sci U S A (1984) 8.93

The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae. Cell (2004) 8.89

Structural identification of a bacterial quorum-sensing signal containing boron. Nature (2002) 8.11

Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones. Microbiology (1997) 7.83

Diffusion of autoinducer is involved in regulation of the Vibrio fischeri luminescence system. J Bacteriol (1985) 7.79

Regulation of gene expression by cell-to-cell communication: acyl-homoserine lactone quorum sensing. Annu Rev Genet (2001) 7.63

Intercellular signalling in Vibrio harveyi: sequence and function of genes regulating expression of luminescence. Mol Microbiol (1993) 7.03

Quorum sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi: a new family of genes responsible for autoinducer production. Proc Natl Acad Sci U S A (1999) 6.89

Bacterial bioluminescence: its control and ecological significance. Microbiol Rev (1979) 6.89

Multiple signalling systems controlling expression of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory pathway. Mol Microbiol (1994) 6.58

Bacterial quorum sensing in pathogenic relationships. Infect Immun (2000) 5.92

Detecting and characterizing N-acyl-homoserine lactone signal molecules by thin-layer chromatography. Proc Natl Acad Sci U S A (1997) 5.39

Parallel quorum sensing systems converge to regulate virulence in Vibrio cholerae. Cell (2002) 5.12

Enzymatic synthesis of a quorum-sensing autoinducer through use of defined substrates. Science (1996) 4.86

Quenching quorum-sensing-dependent bacterial infection by an N-acyl homoserine lactonase. Nature (2001) 4.73

How bacteria talk to each other: regulation of gene expression by quorum sensing. Curr Opin Microbiol (1999) 4.54

Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli. Proc Natl Acad Sci U S A (1999) 4.42

Active efflux and diffusion are involved in transport of Pseudomonas aeruginosa cell-to-cell signals. J Bacteriol (1999) 4.42

Bacteria-host communication: the language of hormones. Proc Natl Acad Sci U S A (2003) 4.38

Small talk. Cell-to-cell communication in bacteria. Cell (2002) 4.27

AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora. Proc Natl Acad Sci U S A (2000) 4.18

QscR, a modulator of quorum-sensing signal synthesis and virulence in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2001) 3.96

A novel regulatory system required for pathogenicity of Xanthomonas campestris is mediated by a small diffusible signal molecule. Mol Microbiol (1997) 3.73

A quorum-sensing signaling system essential for genetic competence in Streptococcus mutans is involved in biofilm formation. J Bacteriol (2002) 3.55

Identification of the operator of the lux regulon from the Vibrio fischeri strain ATCC7744. Proc Natl Acad Sci U S A (1989) 3.52

Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling. J Bacteriol (1996) 3.47

Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA. Nature (2002) 3.45

Quorum sensing is a global regulatory mechanism in enterohemorrhagic Escherichia coli O157:H7. J Bacteriol (2001) 3.43

Rhizobium symbiosis: nod factors in perspective. Plant Cell (1996) 3.42

Molecular basis of symbiotic promiscuity. Microbiol Mol Biol Rev (2000) 3.39

Salmonella typhimurium recognizes a chemically distinct form of the bacterial quorum-sensing signal AI-2. Mol Cell (2004) 3.36

Generation of cell-to-cell signals in quorum sensing: acyl homoserine lactone synthase activity of a purified Vibrio fischeri LuxI protein. Proc Natl Acad Sci U S A (1996) 3.35

Three parallel quorum-sensing systems regulate gene expression in Vibrio harveyi. J Bacteriol (2004) 3.30

Is quorum sensing a side effect of diffusion sensing? Trends Microbiol (2002) 3.18

The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA. EMBO J (2002) 3.11

A novel strategy for the isolation of luxI homologues: evidence for the widespread distribution of a LuxR:LuxI superfamily in enteric bacteria. Mol Microbiol (1993) 3.09

Synergistic binding of the Vibrio fischeri LuxR transcriptional activator domain and RNA polymerase to the lux promoter region. Proc Natl Acad Sci U S A (1994) 3.05

Analogs of the autoinducer 3-oxooctanoyl-homoserine lactone strongly inhibit activity of the TraR protein of Agrobacterium tumefaciens. J Bacteriol (1998) 2.91

The quorum-sensing transcriptional regulator TraR requires its cognate signaling ligand for protein folding, protease resistance, and dimerization. Proc Natl Acad Sci U S A (2001) 2.88

Autoinducer binding by the quorum-sensing regulator TraR increases affinity for target promoters in vitro and decreases TraR turnover rates in whole cells. Proc Natl Acad Sci U S A (1999) 2.87

Quorum sensing in Burkholderia cepacia: identification of the LuxRI homologs CepRI. J Bacteriol (1999) 2.81

The bases of crown gall tumorigenesis. J Bacteriol (2000) 2.81

Critical regions of the Vibrio fischeri luxR protein defined by mutational analysis. J Bacteriol (1990) 2.78

The global posttranscriptional regulator RsmA modulates production of virulence determinants and N-acylhomoserine lactones in Pseudomonas aeruginosa. J Bacteriol (2001) 2.76

Conserved cis-acting promoter elements are required for density-dependent transcription of Agrobacterium tumefaciens conjugal transfer genes. J Bacteriol (1996) 2.68

Use of regulated cell lysis in a lethal genetic selection in Escherichia coli: identification of the autoinducer-binding region of the LuxR protein from Vibrio fischeri ATCC 7744. J Bacteriol (1990) 2.64

A bacterial cell-cell communication signal with cross-kingdom structural analogues. Mol Microbiol (2004) 2.64

Quorum-sensing cross talk: isolation and chemical characterization of cyclic dipeptides from Pseudomonas aeruginosa and other gram-negative bacteria. Mol Microbiol (1999) 2.59

Genetic control of quorum-sensing signal turnover in Agrobacterium tumefaciens. Proc Natl Acad Sci U S A (2002) 2.59

Metabolism of acyl-homoserine lactone quorum-sensing signals by Variovorax paradoxus. J Bacteriol (2000) 2.50

AinS and a new family of autoinducer synthesis proteins. J Bacteriol (1995) 2.47

Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover. Microbiology (2002) 2.41

DNA microarray-based identification of genes controlled by autoinducer 2-stimulated quorum sensing in Escherichia coli. J Bacteriol (2001) 2.40

Activity of purified QscR, a Pseudomonas aeruginosa orphan quorum-sensing transcription factor. Mol Microbiol (2006) 2.38

Quorum sensing and swarming migration in bacteria. FEMS Microbiol Rev (2004) 2.38

Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein. Microbiology (1999) 2.37

The Vibrio fischeri quorum-sensing systems ain and lux sequentially induce luminescence gene expression and are important for persistence in the squid host. Mol Microbiol (2003) 2.35

N-Acyl-L-homoserine lactone autoinducers control production of an extracellular lipopeptide biosurfactant required for swarming motility of Serratia liquefaciens MG1. J Bacteriol (1998) 2.32

LuxS-based signaling in Streptococcus gordonii: autoinducer 2 controls carbohydrate metabolism and biofilm formation with Porphyromonas gingivalis. J Bacteriol (2003) 2.31

Bacterial social engagements. Trends Cell Biol (2004) 2.17

Quorum sensing: the power of cooperation in the world of Pseudomonas. Environ Microbiol (2005) 2.12

Screening for quorum-sensing inhibitors (QSI) by use of a novel genetic system, the QSI selector. J Bacteriol (2005) 2.09

Identification of a global repressor gene, rsmA, of Erwinia carotovora subsp. carotovora that controls extracellular enzymes, N-(3-oxohexanoyl)-L-homoserine lactone, and pathogenicity in soft-rotting Erwinia spp. J Bacteriol (1995) 2.06

Peptide signaling in Staphylococcus aureus and other Gram-positive bacteria. Peptides (2004) 2.05

Quorum sensing in Vibrio fischeri: elements of the luxl promoter. Mol Microbiol (1999) 2.03

Global regulation by CsrA in Salmonella typhimurium. Mol Microbiol (2003) 2.02

Root nodulation and infection factors produced by rhizobial bacteria. Annu Rev Microbiol (2000) 1.99

Vibrio harveyi quorum sensing: a coincidence detector for two autoinducers controls gene expression. EMBO J (2003) 1.99

Chemical communication among bacteria. Proc Natl Acad Sci U S A (2003) 1.98

Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice. J Antimicrob Chemother (2004) 1.96

Regulation of LuxPQ receptor activity by the quorum-sensing signal autoinducer-2. Mol Cell (2005) 1.94

Effect of the Squid Host on the Abundance and Distribution of Symbiotic Vibrio fischeri in Nature. Appl Environ Microbiol (1994) 1.93

Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing. Mol Cell (2002) 1.92

Plants secrete substances that mimic bacterial N-acyl homoserine lactone signal activities and affect population density-dependent behaviors in associated bacteria. Mol Plant Microbe Interact (2000) 1.87

Inhibition of biofilm formation and swarming of Escherichia coli by (5Z)-4-bromo-5-(bromomethylene)-3-butyl-2(5H)-furanone. Environ Microbiol (2001) 1.84

Characterization of the Sinorhizobium meliloti sinR/sinI locus and the production of novel N-acyl homoserine lactones. J Bacteriol (2002) 1.82

Bacteriocin small of Rhizobium leguminosarum belongs to the class of N-acyl-L-homoserine lactone molecules, known as autoinducers and as quorum sensing co-transcription factors. J Bacteriol (1996) 1.79

Quorum sensing in nitrogen-fixing rhizobia. Microbiol Mol Biol Rev (2003) 1.79

Biofilm formation and sloughing in Serratia marcescens are controlled by quorum sensing and nutrient cues. J Bacteriol (2005) 1.75

Acyl-homoserine lactone production is more common among plant-associated Pseudomonas spp. than among soilborne Pseudomonas spp. Appl Environ Microbiol (2001) 1.74

Sequential activation and environmental regulation of virulence genes in Bordetella pertussis. EMBO J (1991) 1.73

Partners-in-infection: host proteins involved in the transformation of plant cells by Agrobacterium. Trends Cell Biol (2002) 1.73

Utilization of acyl-homoserine lactone quorum signals for growth by a soil pseudomonad and Pseudomonas aeruginosa PAO1. Appl Environ Microbiol (2003) 1.71

Agrobacterium bioassay strain for ultrasensitive detection of N-acylhomoserine lactone-type quorum-sensing molecules: detection of autoinducers in Mesorhizobium huakuii. Appl Environ Microbiol (2003) 1.69

The Ti plasmid of Agrobacterium tumefaciens harbors an attM-paralogous gene, aiiB, also encoding N-Acyl homoserine lactonase activity. Appl Environ Microbiol (2003) 1.68

Identity and effects of quorum-sensing inhibitors produced by Penicillium species. Microbiology (2005) 1.67

Quorum sensing in Vibrio fischeri: evidence that S-adenosylmethionine is the amino acid substrate for autoinducer synthesis. J Bacteriol (1996) 1.67

Quorum sensing controls exopolysaccharide production in Sinorhizobium meliloti. J Bacteriol (2003) 1.66

The luxS gene is involved in cell-cell signalling for toxin production in Clostridium perfringens. Mol Microbiol (2002) 1.63

The biocontrol strain Pseudomonas fluorescens F113 produces the Rhizobium small bacteriocin, N-(3-hydroxy-7-cis-tetradecenoyl)homoserine lactone, via HdtS, a putative novel N-acylhomoserine lactone synthase. Microbiology (2000) 1.63

The mechanism of action of S-adenosylhomocysteinase. J Biol Chem (1979) 1.62

Quorum sensing-controlled biofilm development in Serratia liquefaciens MG1. J Bacteriol (2004) 1.62

Crystal structure of the quorum-sensing protein LuxS reveals a catalytic metal site. Proc Natl Acad Sci U S A (2001) 1.62

Characterization of a new efflux pump, MexGHI-OpmD, from Pseudomonas aeruginosa that confers resistance to vanadium. Microbiology (2002) 1.59

Quorum sensing regulates exopolysaccharide production, motility, and virulence in Pseudomonas syringae. Mol Plant Microbe Interact (2005) 1.55

Identification of two quorum-sensing systems in Sinorhizobium meliloti. J Bacteriol (2002) 1.55

Octopine-type Ti plasmids code for a mannopine-inducible dominant-negative allele of traR, the quorum-sensing activator that regulates Ti plasmid conjugal transfer. Mol Microbiol (1998) 1.48