PubRank

Motomi Osato

Author PubWeight™ 46.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell 2002 5.07
2 Heterozygous PU.1 mutations are associated with acute myeloid leukemia. Blood 2002 3.97
3 In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis. Blood 2002 2.50
4 Integrative analysis of RUNX1 downstream pathways and target genes. BMC Genomics 2008 2.14
5 Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations. Am J Hum Genet 2002 1.64
6 RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis. Cancer Cell 2008 1.54
7 Heterozygous PU.1 mutations are associated with acute myeloid leukemia. Blood 2003 1.26
8 Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis. Blood 2009 1.23
9 PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo. Cancer Res 2006 1.22
10 Characterization of GATA-1(+) hemangioblastic cells in the mouse embryo. EMBO J 2006 1.20
11 Runx1 is involved in primitive erythropoiesis in the mouse. Blood 2008 1.11
12 Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult. Stem Cells 2007 1.09
13 Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. Blood 2004 1.09
14 Requirement for Runx proteins in IgA class switching acting downstream of TGF-beta 1 and retinoic acid signaling. J Immunol 2010 1.08
15 A Runx1 intronic enhancer marks hemogenic endothelial cells and hematopoietic stem cells. Stem Cells 2010 1.07
16 Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters. Blood 2011 1.04
17 The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations. Blood 2011 1.02
18 Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML. Blood 2009 0.97
19 Increased dosage of Runx1/AML1 acts as a positive modulator of myeloid leukemogenesis in BXH2 mice. Oncogene 2005 0.94
20 The zebrafish udu gene encodes a novel nuclear factor and is essential for primitive erythroid cell development. Blood 2007 0.94
21 Runx family genes, niche, and stem cell quiescence. Blood Cells Mol Dis 2010 0.92
22 The transcription factor Runx3 represses the neurotrophin receptor TrkB during lineage commitment of dorsal root ganglion neurons. J Biol Chem 2007 0.91
23 Runx3 deficiency results in myeloproliferative disorder in aged mice. Blood 2013 0.90
24 Haploinsufficiency of Runx1/AML1 promotes myeloid features and leukaemogenesis in BXH2 mice. Br J Haematol 2005 0.88
25 Glutamine repeat variants in human RUNX2 associated with decreased femoral neck BMD, broadband ultrasound attenuation and target gene transactivation. PLoS One 2012 0.87
26 Smap1 deficiency perturbs receptor trafficking and predisposes mice to myelodysplasia. J Clin Invest 2013 0.87
27 Functional analysis of RUNX2 mutations in cleidocranial dysplasia: novel insights into genotype-phenotype correlations. Blood Cells Mol Dis 2003 0.86
28 Runx1: no longer just for leukemia. EMBO J 2012 0.85
29 Runx3 is required for full activation of regulatory T cells to prevent colitis-associated tumor formation. J Immunol 2011 0.83
30 Molecular basis for a dominant inactivation of RUNX1/AML1 by the leukemogenic inversion 16 chimera. Blood 2003 0.83
31 In situ differentiation of CD8αα Τ cells from CD4 T cells in peripheral lymphoid tissues. Sci Rep 2012 0.82
32 Stem cell exhaustion and leukemogenesis. J Cell Biochem 2009 0.82
33 cDNA cloning of Runx family genes from the pufferfish (Fugu rubripes). Gene 2007 0.81
34 Polyalanine repeat polymorphism in RUNX2 is associated with site-specific fracture in post-menopausal females. PLoS One 2013 0.80
35 Genetic evidence of PEBP2beta-independent activation of Runx1 in the murine embryo. Int J Hematol 2008 0.79
36 Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia. Blood 2007 0.78
37 Rumba and Haus3 are essential factors for the maintenance of hematopoietic stem/progenitor cells during zebrafish hematopoiesis. Development 2011 0.77
38 Isolation of undifferentiated female germline cells from adult Drosophila ovaries. Curr Protoc Stem Cell Biol 2012 0.76
39 [RUNX family genes and hematopoiesis]. Rinsho Ketsueki 2013 0.75
40 The myeloid features of BXH2 leukemias may result from the lack of one copy of the repetitive sequence in the long terminal repeat viral enhancer. Int J Hematol 2007 0.75
41 Retroviral integration sites (RIS) mark cis-regulatory elements. Crit Rev Oncol Hematol 2008 0.75