Published in Cell Microbiol on December 12, 2006
Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue. PLoS Pathog (2011) 1.02
Impaired CD4 T cell memory response to Streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults. PLoS One (2011) 1.00
Defective pneumococcal-specific Th1 responses in HIV-infected adults precedes a loss of control of pneumococcal colonization. Clin Infect Dis (2012) 1.00
Do multiple concurrent infections in African children cause irreversible immunological damage? Immunology (2012) 0.96
Opa+ and Opa- isolates of Neisseria meningitidis and Neisseria gonorrhoeae induce sustained proliferative responses in human CD4+ T cells. Infect Immun (2009) 0.94
Vibrio cholerae O1 infection induces proinflammatory CD4+ T-cell responses in blood and intestinal mucosa of infected humans. Clin Vaccine Immunol (2011) 0.94
Biofilm formation by the human pathogen Neisseria meningitidis. Med Microbiol Immunol (2010) 0.85
Cerebrospinal-fluid cytokine and chemokine profile in patients with pneumococcal and meningococcal meningitis. BMC Infect Dis (2013) 0.79
Regulation of naturally acquired mucosal immunity to Streptococcus pneumoniae in healthy Malawian adults and children. PLoS One (2012) 0.78
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Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa. Lancet (2012) 4.02
Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype. Genome Res (2009) 3.99
Epidemics of invasive Salmonella enterica serovar enteritidis and S. enterica Serovar typhimurium infection associated with multidrug resistance among adults and children in Malawi. Clin Infect Dis (2008) 3.89
Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa. Nat Genet (2012) 2.86
Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children. Blood (2013) 2.35
Diagnosis of childhood tuberculosis and host RNA expression in Africa. N Engl J Med (2014) 2.12
Clinical management of urinary tract infection in women: a prospective cohort study. Fam Pract (2003) 2.05
Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study. PLoS Med (2013) 1.91
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Invasive non-typhoid salmonellae establish systemic intracellular infection in HIV-infected adults: an emerging disease pathogenesis. Clin Infect Dis (2010) 1.63
The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children. Crit Care (2010) 1.62
Lack of decline in childhood malaria, Malawi, 2001-2010. Emerg Infect Dis (2012) 1.49
Implementing early infant diagnosis of HIV infection at the primary care level: experiences and challenges in Malawi. Bull World Health Organ (2012) 1.48
Typhoid fever and invasive nontyphoid salmonellosis, Malawi and South Africa. Emerg Infect Dis (2010) 1.45
The macrophage marches on its phagosome: dynamic assays of phagosome function. Nat Rev Immunol (2009) 1.43
Ten years of surveillance for invasive Streptococcus pneumoniae during the era of antiretroviral scale-up and cotrimoxazole prophylaxis in Malawi. PLoS One (2011) 1.39
Variation in reported neonatal group B streptococcal disease incidence in developing countries. Clin Infect Dis (2012) 1.38
Brain swelling and death in children with cerebral malaria. N Engl J Med (2015) 1.37
Identification of a common immune signature in murine and human systemic Salmonellosis. Proc Natl Acad Sci U S A (2012) 1.25
The diagnostic and prognostic accuracy of five markers of serious bacterial infection in Malawian children with signs of severe infection. PLoS One (2009) 1.24
Stavudine toxicity in adult longer-term ART patients in Blantyre, Malawi. PLoS One (2012) 1.23
Capture-recapture analysis and pneumococcal meningitis estimates in England. Emerg Infect Dis (2004) 1.21
Surveillance Programme of IN-patients and Epidemiology (SPINE): implementation of an electronic data collection tool within a large hospital in Malawi. PLoS Med (2013) 1.19
Loss of CTL function among high-avidity tumor-specific CD8+ T cells following tumor infiltration. Cancer Res (2008) 1.19
Bronchoalveolar CD4+ T cell responses to respiratory antigens are impaired in HIV-infected adults. Thorax (2011) 1.17
Evaluation of Xpert MTB/RIF for detection of tuberculosis from blood samples of HIV-infected adults confirms Mycobacterium tuberculosis bacteremia as an indicator of poor prognosis. J Clin Microbiol (2013) 1.14
T cell memory response to pneumococcal protein antigens in an area of high pneumococcal carriage and disease. J Infect Dis (2009) 1.08
Epstein-barr virus coinfection in cerebrospinal fluid is associated with increased mortality in Malawian adults with bacterial meningitis. J Infect Dis (2011) 1.04
Genetic characterisation of Malawian pneumococci prior to the roll-out of the PCV13 vaccine using a high-throughput whole genome sequencing approach. PLoS One (2012) 1.03
Bacterial meningitis in Malawian adults, adolescents, and children during the era of antiretroviral scale-up and Haemophilus influenzae type b vaccination, 2000-2012. Clin Infect Dis (2014) 1.02
Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue. PLoS Pathog (2011) 1.02
Deteriorating pneumococcal-specific B-cell memory in minimally symptomatic African children with HIV infection. J Infect Dis (2011) 1.01
Central nervous system compartmentalization of HIV-1 subtype C variants early and late in infection in young children. PLoS Pathog (2012) 1.01
Defective pneumococcal-specific Th1 responses in HIV-infected adults precedes a loss of control of pneumococcal colonization. Clin Infect Dis (2012) 1.00
Impaired CD4 T cell memory response to Streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults. PLoS One (2011) 1.00
Parenteral influenza vaccination influences mucosal and systemic T cell-mediated immunity in healthy adults. J Infect Dis (2004) 1.00
Human immunodeficiency virus (HIV) infection during pregnancy induces CD4 T-cell differentiation and modulates responses to Bacille Calmette-Guérin (BCG) vaccine in HIV-uninfected infants. Immunology (2009) 0.99
High mortality amongst adolescents and adults with bacterial meningitis in sub-Saharan Africa: an analysis of 715 cases from Malawi. PLoS One (2013) 0.99
Mucosal immunity in resource-limited setting: is the battle ground different? Trends Microbiol (2010) 0.98
Rapid emergence of resistance to penicillin and trimethoprim-sulphamethoxazole in invasive Streptococcus pneumoniae in Zimbabwe. Int J Antimicrob Agents (2003) 0.98
Association of human leukocyte antigen alleles and nevirapine hypersensitivity in a Malawian HIV-infected population. Clin Infect Dis (2013) 0.97
Immunoglobulin G subclass response to a meningococcal quadrivalent polysaccharide-diphtheria toxoid conjugate vaccine. Clin Vaccine Immunol (2006) 0.97
Early deaths during tuberculosis treatment are associated with depressed innate responses, bacterial infection, and tuberculosis progression. J Infect Dis (2011) 0.96
Escherichia coli heat-labile enterotoxin B subunit prevents autoimmune arthritis through induction of regulatory CD4+ T cells. Arthritis Rheum (2002) 0.96
Do multiple concurrent infections in African children cause irreversible immunological damage? Immunology (2012) 0.96
Evidence for naturally acquired T cell-mediated mucosal immunity to Neisseria meningitidis. J Immunol (2003) 0.96
A prospective longitudinal study of the clinical outcomes from cryptococcal meningitis following treatment induction with 800 mg oral fluconazole in Blantyre, Malawi. PLoS One (2013) 0.96
British HIV Association guidelines for immunization of HIV-infected adults 2008. HIV Med (2008) 0.95
High prevalence of tuberculosis and serious bloodstream infections in ambulatory individuals presenting for antiretroviral therapy in Malawi. PLoS One (2012) 0.95
Sequential acquisition of T cells and antibodies to nontyphoidal Salmonella in Malawian children. J Infect Dis (2014) 0.94
Potential role for mucosally active vaccines against pneumococcal pneumonia. Trends Microbiol (2009) 0.93
IFN-gamma amplifies NFkappaB-dependent Neisseria meningitidis invasion of epithelial cells via specific upregulation of CEA-related cell adhesion molecule 1. Cell Microbiol (2007) 0.93
Six-month mortality among HIV-infected adults presenting for antiretroviral therapy with unexplained weight loss, chronic fever or chronic diarrhea in Malawi. PLoS One (2012) 0.93
Bacterial meningitis in Malawian infants <2 months of age: etiology and susceptibility to World Health Organization first-line antibiotics. Pediatr Infect Dis J (2014) 0.92
Immune modulation by the cholera-like enterotoxins. Expert Rev Mol Med (2002) 0.92
Critical determinants of the interactions of capsule-expressing Neisseria meningitidis with host cells: the role of receptor density in increased cellular targeting via the outer membrane Opa proteins. Cell Microbiol (2005) 0.92
Modulation of human monocytes by Escherichia coli heat-labile enterotoxin B-subunit; altered cytokine production and its functional consequences. Immunology (2002) 0.92
Persistent endothelial activation and inflammation after Plasmodium falciparum Infection in Malawian children. J Infect Dis (2013) 0.91
Mutant Escherichia coli heat-labile toxin B subunit that separates toxoid-mediated signaling and immunomodulatory action from trafficking and delivery functions. Infect Immun (2003) 0.89
Modulation of the immune response by the cholera-like enterotoxins. Curr Top Med Chem (2004) 0.88
The human transcriptome during nontyphoid Salmonella and HIV coinfection reveals attenuated NFkappaB-mediated inflammation and persistent cell cycle disruption. J Infect Dis (2011) 0.87
Drug resistance in Salmonella enterica ser. Typhimurium bloodstream infection, Malawi. Emerg Infect Dis (2014) 0.87
CD8+ T cell apoptosis induced by Escherichia coli heat-labile enterotoxin B subunit occurs via a novel pathway involving NF-kappaB-dependent caspase activation. Eur J Immunol (2002) 0.87
The role of intercellular adhesion molecule-1/LFA-1 interactions in the generation of tumor-specific CD8+ T cell responses. J Immunol (2005) 0.87
Genotypic homogeneity of multidrug resistant S. Typhimurium infecting distinct adult and childhood susceptibility groups in Blantyre, Malawi. PLoS One (2012) 0.86
Mucosal immunity in healthy adults after parenteral vaccination with outer-membrane vesicles from Neisseria meningitidis serogroup B. J Infect Dis (2008) 0.86
Recognising and treatment seeking for acute bacterial meningitis in adults and children in resource-poor settings: a qualitative study. PLoS One (2013) 0.85
The B subunit of Escherichia coli heat-labile enterotoxin inhibits Th1 but not Th17 cell responses in established experimental autoimmune uveoretinitis. Invest Ophthalmol Vis Sci (2008) 0.85
Intranasal immunisation of mice with liposomes containing recombinant meningococcal OpaB and OpaJ proteins. Vaccine (2004) 0.84
The B subunit of Escherichia coli heat labile enterotoxin abrogates oral tolerance, promoting predominantly Th2-type immune responses. Eur J Immunol (2003) 0.84
Population pharmacokinetic and pharmacogenetic analysis of nevirapine in hypersensitive and tolerant HIV-infected patients from Malawi. Antimicrob Agents Chemother (2013) 0.83
The B subunit of Escherichia coli heat-labile enterotoxin induces both caspase-dependent and -independent cell death pathways in CD8+ T cells. Infect Immun (2004) 0.83
Regulation of intestinal immunity: effects of the oral adjuvant Escherichia coli heat-labile enterotoxin on migrating dendritic cells. Eur J Immunol (2007) 0.82
Nasal delivery of antigen with the B subunit of Escherichia coli heat-labile enterotoxin augments antigen-specific T-cell clonal expansion and differentiation. Infect Immun (2004) 0.82
Impaired maintenance of naturally acquired T-cell memory to the meningococcus in patients with B-cell immunodeficiency. Blood (2009) 0.82
Household air pollution causes dose-dependent inflammation and altered phagocytosis in human macrophages. Am J Respir Cell Mol Biol (2015) 0.82
Modulation of B lymphocyte signalling by the B subunit of Escherichia coli heat-labile enterotoxin. Int Immunol (2002) 0.82
Phage-display derived single-chain fragment variable (scFv) antibodies recognizing conformational epitopes of Escherichia coli heat-labile enterotoxin B-subunit. J Immunol Methods (2008) 0.82
Lumbar puncture in the management of adults with suspected bacterial meningitis--a survey of practice. J Infect (2005) 0.82
Genomic identification of a novel co-trimoxazole resistance genotype and its prevalence amongst Streptococcus pneumoniae in Malawi. J Antimicrob Chemother (2013) 0.81
Human tonsil-derived dendritic cells are poor inducers of T cell immunity to mucosally encountered pathogens. J Infect Dis (2013) 0.81
Protection of non-obese diabetic mice from autoimmune diabetes by Escherichia coli heat-labile enterotoxin B subunit. Immunology (2006) 0.80