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Decreased fragile X mental retardation protein expression underlies amygdala dysfunction in carriers of the fragile X premutation. Biol Psychiatry (2011) 1.59

Fragile X-associated tremor/ataxia syndrome (FXTAS): pathology and mechanisms. Acta Neuropathol (2013) 1.41

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Fragile X: a family of disorders. Adv Pediatr (2009) 1.30

A mouse model of the fragile X premutation: effects on behavior, dendrite morphology, and regional rates of cerebral protein synthesis. Neurobiol Dis (2011) 1.18

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Reduced Hippocampal Activation During Recall is Associated with Elevated FMR1 mRNA and Psychiatric Symptoms in Men with the Fragile X Premutation. Brain Imaging Behav (2008) 1.14

Psychological symptoms correlate with reduced hippocampal volume in fragile X premutation carriers. Am J Med Genet B Neuropsychiatr Genet (2010) 1.14

Fragile X-associated disorders: a clinical overview. J Neurol (2011) 1.13

Fibroblast phenotype in male carriers of FMR1 premutation alleles. Hum Mol Genet (2009) 1.11

A voxel-based morphometry study of grey matter loss in fragile X-associated tremor/ataxia syndrome. Brain (2011) 1.09

Somatic expansion in mouse and human carriers of fragile X premutation alleles. Hum Mutat (2012) 1.09

Abnormal structure or function of the amygdala is a common component of neurodevelopmental disorders. Neuropsychologia (2010) 1.06

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Defining genetically meaningful language and personality traits in relatives of individuals with fragile X syndrome and relatives of individuals with autism. Am J Med Genet B Neuropsychiatr Genet (2012) 0.96

Impaired activity-dependent FMRP translation and enhanced mGluR-dependent LTD in Fragile X premutation mice. Hum Mol Genet (2012) 0.95

Broad clinical involvement in a family affected by the fragile X premutation. J Dev Behav Pediatr (2009) 0.94

Aripiprazole in autism spectrum disorders and fragile X syndrome. Neurotherapeutics (2010) 0.92

Wired for behaviors: from development to function of innate limbic system circuitry. Front Mol Neurosci (2012) 0.92

Fragile X spectrum disorders. Intractable Rare Dis Res (2014) 0.91

Prefrontal social cognition network dysfunction underlying face encoding and social anxiety in fragile X syndrome. Neuroimage (2008) 0.89

Spatiotemporal processing deficits in female CGG KI mice modeling the fragile X premutation. Behav Brain Res (2012) 0.87

Autism spectrum disorder: does neuroimaging support the DSM-5 proposal for a symptom dyad? A systematic review of functional magnetic resonance imaging and diffusion tensor imaging studies. J Autism Dev Disord (2012) 0.87

Fragile x-associated tremor ataxia syndrome: the expanding clinical picture, pathophysiology, epidemiology, and update on treatment. Tremor Other Hyperkinet Mov (N Y) (2012) 0.86

Comprehensive neurocognitive endophenotyping strategies for mouse models of genetic disorders. Prog Neurobiol (2012) 0.86

Unstable mutations in the FMR1 gene and the phenotypes. Adv Exp Med Biol (2012) 0.84

Dementia in Down's syndrome: an MRI comparison with Alzheimer's disease in the general population. J Neurodev Disord (2013) 0.83

Biomarkers in the Study of Families of Individuals with Developmental Disabilities. Int Rev Res Ment Retard (2009) 0.82

Repeat-mediated genetic and epigenetic changes at the FMR1 locus in the Fragile X-related disorders. Front Genet (2014) 0.82

Conversion disorder in women with the FMR1 premutation. Am J Med Genet A (2009) 0.81

Neural phenotypes of common and rare genetic variants. Biol Psychol (2008) 0.81

Fear-specific amygdala function in children and adolescents on the fragile x spectrum: a dosage response of the FMR1 gene. Cereb Cortex (2012) 0.80

Male carriers of the FMR1 premutation show altered hippocampal-prefrontal function during memory encoding. Front Hum Neurosci (2012) 0.80

COGNITIVE DYSFUNCTION IN FMR1 PREMUTATION CARRIERS. Curr Psychiatry Rev (2013) 0.79

The genetics of anxiety-related negative valence system traits. Am J Med Genet B Neuropsychiatr Genet (2016) 0.79

Emotion recognition and visual-scan paths in Fragile X syndrome. J Autism Dev Disord (2013) 0.78

Towards an Understanding of Neuropsychiatric Manifestations in Fragile X Premutation Carriers. Future Neurol (2014) 0.78

Anxiety disorders in fragile X premutation carriers: Preliminary characterization of probands and non-probands. Intractable Rare Dis Res (2015) 0.78

Face scanning and spontaneous emotion preference in Cornelia de Lange syndrome and Rubinstein-Taybi syndrome. J Neurodev Disord (2015) 0.77

Investigation of amygdala volume in men with the fragile X premutation. Brain Imaging Behav (2011) 0.77

Broad autism spectrum and obsessive-compulsive symptoms in adults with the fragile X premutation. Clin Neuropsychol (2016) 0.77

Overexpression of Homer1a in the basal and lateral amygdala impairs fear conditioning and induces an autism-like social impairment. Mol Autism (2016) 0.77

Immune mediated disorders in women with a fragile X expansion and FXTAS. Am J Med Genet A (2014) 0.76

Emotion potentiated startle in fragile X syndrome. J Autism Dev Disord (2014) 0.76

Pragmatic Language in autism and fragile X syndrome: Genetic and clinical applications. Perspect Lang Learn Educ (2012) 0.76

Altered structural brain connectome in young adult fragile X premutation carriers. Hum Brain Mapp (2014) 0.76

Reduced vagal tone in women with the FMR1 premutation is associated with FMR1 mRNA but not depression or anxiety. J Neurodev Disord (2017) 0.75

The fragile X mental retardation 1 gene (FMR1): historical perspective, phenotypes, mechanism, pathology, and epidemiology. Clin Neuropsychol (2016) 0.75

Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS) Motor Dysfunction Modeled in Mice. Cerebellum (2016) 0.75

Moving Toward Integrative, Multidimensional Research in Modern Psychiatry: Lessons Learned From Fragile X Syndrome. Biol Psychiatry (2015) 0.75

The quality of health care delivered to adults in the United States. N Engl J Med (2003) 50.33

Comparison of quality of care for patients in the Veterans Health Administration and patients in a national sample. Ann Intern Med (2004) 6.86

Fragile X premutation tremor/ataxia syndrome: molecular, clinical, and neuroimaging correlates. Am J Hum Genet (2003) 5.51

Results of the National Initiative for Cancer Care Quality: how can we improve the quality of cancer care in the United States? J Clin Oncol (2006) 5.40

The quality of medical care provided to vulnerable community-dwelling older patients. Ann Intern Med (2003) 5.28

Penetrance of the fragile X-associated tremor/ataxia syndrome in a premutation carrier population. JAMA (2004) 4.88

The fragile-X premutation: a maturing perspective. Am J Hum Genet (2004) 3.89

The FMR1 premutation and reproduction. Fertil Steril (2006) 3.85

A rapid polymerase chain reaction-based screening method for identification of all expanded alleles of the fragile X (FMR1) gene in newborn and high-risk populations. J Mol Diagn (2007) 3.80

Epigenetic modification of the FMR1 gene in fragile X syndrome is associated with differential response to the mGluR5 antagonist AFQ056. Sci Transl Med (2011) 3.46

The quality of pharmacologic care for vulnerable older patients. Ann Intern Med (2004) 3.34

Prenatal vitamins, one-carbon metabolism gene variants, and risk for autism. Epidemiology (2011) 3.15

Validity of cancer registry data for measuring the quality of breast cancer care. J Natl Cancer Inst (2002) 3.00

Expanded clinical phenotype of women with the FMR1 premutation. Am J Med Genet A (2008) 2.91

FMR1 RNA within the intranuclear inclusions of fragile X-associated tremor/ataxia syndrome (FXTAS). RNA Biol (2004) 2.90

Phoneme awareness is a better predictor of early reading skill than onset-rime awareness. J Exp Child Psychol (2002) 2.89

Autism spectrum disorders and attention-deficit/hyperactivity disorder in boys with the fragile X premutation. J Dev Behav Pediatr (2006) 2.73

The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome. Hum Mol Genet (2003) 2.73

Patients' global ratings of their health care are not associated with the technical quality of their care. Ann Intern Med (2006) 2.68

Fragile X-associated tremor/ataxia syndrome: clinical features, genetics, and testing guidelines. Mov Disord (2007) 2.68

Fragile X premutation carriers: characteristic MR imaging findings of adult male patients with progressive cerebellar and cognitive dysfunction. AJNR Am J Neuroradiol (2002) 2.58

Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial. Sci Transl Med (2012) 2.51

Specificity and sensitivity of claims-based algorithms for identifying members of Medicare+Choice health plans that have chronic medical conditions. Health Serv Res (2004) 2.50

Quality-of-care indicators for early-stage prostate cancer. J Clin Oncol (2003) 2.44

Sam68 sequestration and partial loss of function are associated with splicing alterations in FXTAS patients. EMBO J (2010) 2.43

A practice-based intervention to improve primary care for falls, urinary incontinence, and dementia. J Am Geriatr Soc (2009) 2.36

Abnormal elevation of FMR1 mRNA is associated with psychological symptoms in individuals with the fragile X premutation. Am J Med Genet B Neuropsychiatr Genet (2005) 2.35

Autism profiles of males with fragile X syndrome. Am J Ment Retard (2008) 2.35

An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals. Hum Mol Genet (2007) 2.25

Use of ambulance dispatch data as an early warning system for communitywide influenzalike illness, New York City. J Urban Health (2003) 2.18

Induction of inclusion formation and disruption of lamin A/C structure by premutation CGG-repeat RNA in human cultured neural cells. Hum Mol Genet (2005) 2.17

The fragile X premutation: into the phenotypic fold. Curr Opin Genet Dev (2002) 2.15

Maternal periconceptional folic acid intake and risk of autism spectrum disorders and developmental delay in the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study. Am J Clin Nutr (2012) 2.14

Age-dependent cognitive changes in carriers of the fragile X syndrome. Cortex (2007) 2.10

Phenotypic variation and FMRP levels in fragile X. Ment Retard Dev Disabil Res Rev (2004) 2.07

Combining multiple indicators of clinical quality: an evaluation of different analytic approaches. Med Care (2007) 2.07

Reduced FMR1 mRNA translation efficiency in fragile X patients with premutations. RNA (2002) 2.06

Sequencing the unsequenceable: expanded CGG-repeat alleles of the fragile X gene. Genome Res (2012) 2.04

Mitochondrial dysfunction in autism. JAMA (2010) 2.04

The Prader-Willi phenotype of fragile X syndrome. J Dev Behav Pediatr (2007) 2.02

Fragile-X syndrome and fragile X-associated tremor/ataxia syndrome: two faces of FMR1. Lancet Neurol (2007) 2.00

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Murine hippocampal neurons expressing Fmr1 gene premutations show early developmental deficits and late degeneration. Hum Mol Genet (2010) 1.95

Plasmodium vivax invasion of human erythrocytes inhibited by antibodies directed against the Duffy binding protein. PLoS Med (2007) 1.95

Screening for expanded alleles of the FMR1 gene in blood spots from newborn males in a Spanish population. J Mol Diagn (2009) 1.94

Newborn screening in North America. J Inherit Metab Dis (2007) 1.93

An enhanced polymerase chain reaction assay to detect pre- and full mutation alleles of the fragile X mental retardation 1 gene. J Mol Diagn (2005) 1.91

Elevated FMR1 mRNA in premutation carriers is due to increased transcription. RNA (2007) 1.87

A novel FMR1 PCR method for the routine detection of low abundance expanded alleles and full mutations in fragile X syndrome. Clin Chem (2010) 1.86

The quality of pharmacologic care for adults in the United States. Med Care (2006) 1.85

Advances in understanding the molecular basis of FXTAS. Hum Mol Genet (2010) 1.83

The (CGG)n repeat element within the 5' untranslated region of the FMR1 message provides both positive and negative cis effects on in vivo translation of a downstream reporter. Hum Mol Genet (2003) 1.82

Psychiatric phenotype of the fragile X-associated tremor/ataxia syndrome (FXTAS) in males: newly described fronto-subcortical dementia. J Clin Psychiatry (2006) 1.80

Lifetime prevalence of mood and anxiety disorders in fragile X premutation carriers. J Clin Psychiatry (2010) 1.79

Progression of tremor and ataxia in male carriers of the FMR1 premutation. Mov Disord (2007) 1.77

Cognitive profile of fragile X premutation carriers with and without fragile X-associated tremor/ataxia syndrome. Neuropsychology (2008) 1.75

Impairment in the cognitive functioning of men with fragile X-associated tremor/ataxia syndrome (FXTAS). J Neurol Sci (2006) 1.75

Practice redesign to improve care for falls and urinary incontinence: primary care intervention for older patients. Arch Intern Med (2010) 1.74

Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D. J Clin Endocrinol Metab (2010) 1.72

Fragile X-associated tremor/ataxia syndrome (FXTAS). Ment Retard Dev Disabil Res Rev (2004) 1.68

The malaria secretome: from algorithms to essential function in blood stage infection. PLoS Pathog (2008) 1.67

Quality of health care for women: a demonstration of the quality assessment tools system. Med Care (2003) 1.66

CGG repeat length correlates with age of onset of motor signs of the fragile X-associated tremor/ataxia syndrome (FXTAS). Am J Med Genet B Neuropsychiatr Genet (2007) 1.66