Published in EMBO Rep on December 15, 2006
The Mcm complex: unwinding the mechanism of a replicative helicase. Microbiol Mol Biol Rev (2009) 2.29
Reduced expression of GINS complex members induces hallmarks of pre-malignancy in primary untransformed human cells. Cell Cycle (2009) 1.49
Crystal structure of the GINS complex and functional insights into its role in DNA replication. Proc Natl Acad Sci U S A (2007) 1.36
The human GINS complex associates with Cdc45 and MCM and is essential for DNA replication. Nucleic Acids Res (2009) 1.35
Crystal structure of the human GINS complex. Genes Dev (2007) 1.25
Studies on human DNA polymerase epsilon and GINS complex and their role in DNA replication. J Biol Chem (2011) 1.21
Molecular architecture of the human GINS complex. EMBO Rep (2007) 1.07
Architectures of archaeal GINS complexes, essential DNA replication initiation factors. BMC Biol (2011) 0.96
Regulation of the cell division cycle in Trypanosoma brucei. Eukaryot Cell (2012) 0.94
DNA replication and homologous recombination factors: acting together to maintain genome stability. Chromosoma (2013) 0.92
Transcriptional responses to loss of RNase H2 in Saccharomyces cerevisiae. DNA Repair (Amst) (2012) 0.88
Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2. Neoplasia (2010) 0.88
Drosophila Sld5 is essential for normal cell cycle progression and maintenance of genomic integrity. Biochem Biophys Res Commun (2010) 0.87
GINS inactivation phenotypes reveal two pathways for chromatin association of replicative alpha and epsilon DNA polymerases in fission yeast. Mol Biol Cell (2008) 0.84
DNA replication and the GINS complex: localization on extended chromatin fibers. Epigenetics Chromatin (2009) 0.84
The mini-chromosome maintenance (Mcm) complexes interact with DNA polymerase α-primase and stimulate its ability to synthesize RNA primers. PLoS One (2013) 0.79
The Sulfolobus solfataricus GINS Complex Stimulates DNA Binding and Processive DNA Unwinding by Minichromosome Maintenance Helicase. J Bacteriol (2015) 0.77
New insights into the GINS complex explain the controversy between existing structural models. Sci Rep (2017) 0.76
GINS maintains association of Cdc45 with MCM in replisome progression complexes at eukaryotic DNA replication forks. Nat Cell Biol (2006) 6.36
Isolation of the Cdc45/Mcm2-7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase. Proc Natl Acad Sci U S A (2006) 5.66
Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. Mol Cell (2006) 3.77
GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Genes Dev (2003) 3.53
Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo. Nature (2003) 3.08
Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork. Genes Dev (2005) 3.07
A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication. Genes Dev (2003) 2.75
Xenopus Cdc45-dependent loading of DNA polymerase alpha onto chromatin under the control of S-phase Cdk. EMBO J (1998) 2.66
Pumps, paradoxes and ploughshares: mechanism of the MCM2-7 DNA helicase. Trends Biochem Sci (2005) 2.53
Mcm10 regulates the stability and chromatin association of DNA polymerase-alpha. Mol Cell (2004) 2.52
Dpb11 controls the association between DNA polymerases alpha and epsilon and the autonomously replicating sequence region of budding yeast. Mol Cell Biol (2000) 2.35
Biochemical and functional comparison of DNA polymerases alpha, delta, and epsilon from calf thymus. J Biol Chem (1991) 2.08
GINS, a central nexus in the archaeal DNA replication fork. EMBO Rep (2006) 1.91
The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair. Nucleic Acids Res (2004) 1.63
PSF1 is essential for early embryogenesis in mice. Mol Cell Biol (2005) 1.40
Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p. J Biol Chem (2004) 1.37
Human DNA polymerase lambda possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions. J Mol Biol (2003) 1.21
Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation. Mol Cell Biol (2005) 1.20
Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma. Oncol Rep (2005) 1.09
Primase activity of human DNA polymerase alpha-primase. Divalent cations stabilize the enzyme activity of the p48 subunit. J Biol Chem (1998) 1.06
8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteins. Nature (2007) 2.32
The ubiquitin-selective segregase VCP/p97 orchestrates the response to DNA double-strand breaks. Nat Cell Biol (2011) 2.15
The 3' 5' exonucleases. Nat Rev Mol Cell Biol (2002) 2.07
Mammalian base excision repair: the forgotten archangel. Nucleic Acids Res (2013) 1.79
Deinococcus radiodurans: what belongs to the survival kit? Crit Rev Biochem Mol Biol (2008) 1.78
Oxygen as a friend and enemy: How to combat the mutational potential of 8-oxo-guanine. DNA Repair (Amst) (2010) 1.70
The human Rad9/Rad1/Hus1 damage sensor clamp interacts with DNA polymerase beta and increases its DNA substrate utilisation efficiency: implications for DNA repair. Nucleic Acids Res (2004) 1.63
Arginine methylation regulates DNA polymerase beta. Mol Cell (2006) 1.57
Structural basis for natural lactonase and promiscuous phosphotriesterase activities. J Mol Biol (2008) 1.43
Incorporation of reporter molecule-labeled nucleotides by DNA polymerases. II. High-density labeling of natural DNA. Nucleic Acids Res (2003) 1.39
Physical and functional interaction between the mini-chromosome maintenance-like DNA helicase and the single-stranded DNA binding protein from the crenarchaeon Sulfolobus solfataricus. J Biol Chem (2002) 1.37
Phosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulation. Oncogene (2003) 1.30
The hyperthermophilic euryarchaeota Pyrococcus abyssi likely requires the two DNA polymerases D and B for DNA replication. J Mol Biol (2005) 1.29
The human checkpoint sensor and alternative DNA clamp Rad9-Rad1-Hus1 modulates the activity of DNA ligase I, a component of the long-patch base excision repair machinery. Biochem J (2005) 1.29
Human DNA polymerase lambda diverged in evolution from DNA polymerase beta toward specific Mn(++) dependence: a kinetic and thermodynamic study. Biochemistry (2003) 1.29
A thermostable phosphotriesterase from the archaeon Sulfolobus solfataricus: cloning, overexpression and properties. Extremophiles (2005) 1.27
Human DNA polymerase lambda functionally and physically interacts with proliferating cell nuclear antigen in normal and translesion DNA synthesis. J Biol Chem (2002) 1.27
The two DNA clamps Rad9/Rad1/Hus1 complex and proliferating cell nuclear antigen differentially regulate flap endonuclease 1 activity. J Mol Biol (2005) 1.25
The DNA-polymerase-X family: controllers of DNA quality? Nat Rev Mol Cell Biol (2004) 1.24
The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair. EMBO J (2002) 1.23
An 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase lambda. Proc Natl Acad Sci U S A (2009) 1.23
Replication protein A and proliferating cell nuclear antigen coordinate DNA polymerase selection in 8-oxo-guanine repair. Proc Natl Acad Sci U S A (2008) 1.23
Structural analysis of the Sulfolobus solfataricus MCM protein N-terminal domain. Nucleic Acids Res (2008) 1.22
Human DNA polymerase lambda possesses terminal deoxyribonucleotidyl transferase activity and can elongate RNA primers: implications for novel functions. J Mol Biol (2003) 1.21
Flap endonuclease 1: a novel tumour suppresser protein. Trends Biochem Sci (2003) 1.20
Human DNA polymerases lambda and beta show different efficiencies of translesion DNA synthesis past abasic sites and alternative mechanisms for frameshift generation. Biochemistry (2004) 1.18
Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus at 1.85 A resolution. J Mol Biol (2002) 1.17
De novo DNA synthesis by human DNA polymerase lambda, DNA polymerase mu and terminal deoxyribonucleotidyl transferase. J Mol Biol (2004) 1.17
The acetylatable lysines of human Fen1 are important for endo- and exonuclease activities. J Mol Biol (2003) 1.16
The checkpoint clamp, Rad9-Rad1-Hus1 complex, preferentially stimulates the activity of apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta in long patch base excision repair. Nucleic Acids Res (2007) 1.16
Proteins from extremophiles as stable tools for advanced biotechnological applications of high social interest. J R Soc Interface (2007) 1.15
DNA polymerase theta purified from human cells is a high-fidelity enzyme. J Mol Biol (2002) 1.12
Archaeal DNA replication: spotlight on a rapidly moving field. Extremophiles (2002) 1.09
The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNA. Nucleic Acids Res (2005) 1.08
Recoding in archaea. Mol Microbiol (2005) 1.07
Erroneous incorporation of oxidized DNA precursors by Y-family DNA polymerases. EMBO Rep (2003) 1.06
Crystal structure of a ternary complex of the alcohol dehydrogenase from Sulfolobus solfataricus. Biochemistry (2003) 1.06
The Fen1 extrahelical 3'-flap pocket is conserved from archaea to human and regulates DNA substrate specificity. Nucleic Acids Res (2004) 1.05
Control of DNA polymerase lambda stability by phosphorylation and ubiquitination during the cell cycle. EMBO Rep (2008) 1.05
Biochemical characterization of a CDC6-like protein from the crenarchaeon Sulfolobus solfataricus. J Biol Chem (2003) 1.05
Methylation of DNA polymerase beta by protein arginine methyltransferase 1 regulates its binding to proliferating cell nuclear antigen. FASEB J (2006) 1.04
A novel proteomic approach identifies new interaction partners for proliferating cell nuclear antigen. J Mol Biol (2007) 1.04
Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination. Proc Natl Acad Sci U S A (2011) 1.04
Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins. EMBO J (2002) 1.03
Structural and functional insights into the DNA replication factor Cdc45 reveal an evolutionary relationship to the DHH family of phosphoesterases. J Biol Chem (2011) 1.03
Mutagenesis of human DNA polymerase lambda: essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities. Nucleic Acids Res (2003) 1.02
Involvement of an X family DNA polymerase in double-stranded break repair in the radioresistant organism Deinococcus radiodurans. Mol Microbiol (2004) 1.02
Processing of DNA lesions by archaeal DNA polymerases from Sulfolobus solfataricus. Nucleic Acids Res (2003) 1.02
Reverse gyrase recruitment to DNA after UV light irradiation in Sulfolobus solfataricus. J Biol Chem (2004) 1.00
Insights into DNA replication: the crystal structure of DNA polymerase B1 from the archaeon Sulfolobus solfataricus. Structure (2004) 1.00
Selective degradation of reverse gyrase and DNA fragmentation induced by alkylating agent in the archaeon Sulfolobus solfataricus. Nucleic Acids Res (2006) 1.00
Amino acids of the Sulfolobus solfataricus mini-chromosome maintenance-like DNA helicase involved in DNA binding/remodeling. J Biol Chem (2004) 1.00
Functional properties of the protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus: a member of a novel protein family related to protein disulfide-isomerase. Eur J Biochem (2004) 0.99
Error-free bypass of 2-hydroxyadenine by human DNA polymerase lambda with Proliferating Cell Nuclear Antigen and Replication Protein A in different sequence contexts. Nucleic Acids Res (2007) 0.99
Modular organization of the Sulfolobus solfataricus mini-chromosome maintenance protein. J Biol Chem (2007) 0.99
Nevirapine-selected mutations Y181I/C of HIV-1 reverse transcriptase confer cross-resistance to stavudine. AIDS (2003) 0.99
Regulation of the DNA replication fork: a way to fight genomic instability. Chromosoma (2004) 0.98
Structural determinants of the high thermal stability of SsoPox from the hyperthermophilic archaeon Sulfolobus solfataricus. Extremophiles (2009) 0.98
Reverse gyrase and genome stability in hyperthermophilic organisms. Biochem Soc Trans (2009) 0.98
Translational recoding in archaea. Extremophiles (2012) 0.98
Multiple roles for kinases in DNA replication. EMBO Rep (2003) 0.97
A carboxylesterase from the hyperthermophilic archaeon Sulfolobus solfataricus: cloning of the gene, characterization of the protein. Gene (2002) 0.97
Characterization and functional complementation of a nonlethal deletion in the chromosome of a beta-glycosidase mutant of Sulfolobus solfataricus. J Bacteriol (2003) 0.97
DNA polymerase beta can incorporate ribonucleotides during DNA synthesis of undamaged and CPD-damaged DNA. J Mol Biol (2003) 0.96
DNA polymerase X from Deinococcus radiodurans possesses a structure-modulated 3'-->5' exonuclease activity involved in radioresistance. Mol Microbiol (2006) 0.96
The human DNA polymerase lambda interacts with PCNA through a domain important for DNA primer binding and the interaction is inhibited by p21/WAF1/CIP1. FASEB J (2004) 0.96
A new phosphotriesterase from Sulfolobus acidocaldarius and its comparison with the homologue from Sulfolobus solfataricus. Biochimie (2007) 0.96
Dissection of reverse gyrase activities: insight into the evolution of a thermostable molecular machine. Nucleic Acids Res (2008) 0.95
The initiation step of eukaryotic DNA replication. Subcell Biochem (2010) 0.95
Transcriptional response to DNA damage in the archaeon Sulfolobus solfataricus. Nucleic Acids Res (2003) 0.95
Characterization of a beta-glycosidase from the thermoacidophilic bacterium Alicyclobacillus acidocaldarius. Extremophiles (2006) 0.95
A switch between DNA polymerases δ and λ promotes error-free bypass of 8-oxo-G lesions. Proc Natl Acad Sci U S A (2012) 0.94
The family X DNA polymerase from Deinococcus radiodurans adopts a non-standard extended conformation. J Biol Chem (2009) 0.94
Transcriptional regulation of the gene encoding an alcohol dehydrogenase in the archaeon Sulfolobus solfataricus involves multiple factors and control elements. J Bacteriol (2003) 0.94
MarR-like transcriptional regulator involved in detoxification of aromatic compounds in Sulfolobus solfataricus. J Bacteriol (2007) 0.94
Role of the N terminus in enzyme activity, stability and specificity in thermophilic esterases belonging to the HSL family. J Mol Biol (2005) 0.94
A spreadable, non-integrative and high copy number shuttle vector for Sulfolobus solfataricus based on the genetic element pSSVx from Sulfolobus islandicus. Nucleic Acids Res (2006) 0.93
Regulation of oxidative DNA damage repair: the adenine:8-oxo-guanine problem. Cell Cycle (2012) 0.93
Structural characterization of the nonameric assembly of an Archaeal alpha-L-fucosidase by synchrotron small angle X-ray scattering. Biochem Biophys Res Commun (2004) 0.93
Molecular biology of extremophiles: recent progress on the hyperthermophilic archaeon Sulfolobus. Antonie Van Leeuwenhoek (2002) 0.93