James M Murphy

Author PubWeight™ 79.03‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The alcohol-preferring P rat and animal models of excessive alcohol drinking. Addict Biol 2006 2.82
2 Improved surface temperature prediction for the coming decade from a global climate model. Science 2007 2.65
3 Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity. Immunity 2012 2.30
4 cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner. Blood 2014 1.97
5 Recent advances in animal models of alcohol craving and relapse. Pharmacol Biochem Behav 2004 1.72
6 Intracranial self-administration of ethanol within the ventral tegmental area of male Wistar rats: evidence for involvement of dopamine neurons. J Neurosci 2004 1.65
7 Daily patterns of ethanol drinking in peri-adolescent and adult alcohol-preferring (P) rats. Pharmacol Biochem Behav 2006 1.46
8 Regional heterogeneity for the intracranial self-administration of ethanol and acetaldehyde within the ventral tegmental area of alcohol-preferring (P) rats: involvement of dopamine and serotonin. Neuropsychopharmacology 2005 1.43
9 Screening for PTB domain binding partners and ligand specificity using proteome-derived NPXY peptide arrays. Mol Cell Biol 2006 1.41
10 SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition. Nat Struct Mol Biol 2013 1.38
11 A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties. Biochem J 2014 1.33
12 Effects of repeated alcohol deprivations on operant ethanol self-administration by alcohol-preferring (P) rats. Neuropsychopharmacology 2003 1.31
13 Microdialysis of dopamine in the nucleus accumbens of alcohol-preferring (P) rats during anticipation and operant self-administration of ethanol. Alcohol Clin Exp Res 2002 1.31
14 Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats: I. Periadolescent exposure. Alcohol Clin Exp Res 2002 1.26
15 Cocaine is self-administered into the shell but not the core of the nucleus accumbens of Wistar rats. J Pharmacol Exp Ther 2002 1.23
16 The metabotropic glutamate 2/3 receptor agonist LY404039 reduces alcohol-seeking but not alcohol self-administration in alcohol-preferring (P) rats. Behav Brain Res 2006 1.23
17 Effects of ethanol exposure on subsequent acquisition and extinction of ethanol self-administration and expression of alcohol-seeking behavior in adult alcohol-preferring (P) rats: II. Adult exposure. Alcohol Clin Exp Res 2002 1.22
18 Neuropeptide Y reduces oral ethanol intake in alcohol-preferring (P) rats following a period of imposed ethanol abstinence. Alcohol Clin Exp Res 2003 1.15
19 Adolescent alcohol drinking and its long-range consequences. Studies with animal models. Recent Dev Alcohol 2005 1.11
20 Intracranial self-administration of cocaine within the posterior ventral tegmental area of Wistar rats: evidence for involvement of serotonin-3 receptors and dopamine neurons. J Pharmacol Exp Ther 2005 1.11
21 Critical roles for c-Myb in lymphoid priming and early B-cell development. Blood 2010 1.09
22 Comparison of intracranial self-administration of ethanol within the posterior ventral tegmental area between alcohol-preferring and Wistar rats. Alcohol Clin Exp Res 2004 1.09
23 Ethanol is self-administered into the nucleus accumbens shell, but not the core: evidence of genetic sensitivity. Alcohol Clin Exp Res 2009 1.09
24 Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL. Biochem J 2014 1.07
25 Prolonged increase in the sensitivity of the posterior ventral tegmental area to the reinforcing effects of ethanol following repeated exposure to cycles of ethanol access and deprivation. J Pharmacol Exp Ther 2005 1.04
26 Effects of concurrent access to a single concentration or multiple concentrations of ethanol on ethanol intake by periadolescent high-alcohol-drinking rats. Alcohol 2004 1.01
27 Chronic ethanol drinking by alcohol-preferring rats increases the sensitivity of the posterior ventral tegmental area to the reinforcing effects of ethanol. Alcohol Clin Exp Res 2005 1.01
28 Extracellular dopamine levels are lower in the medial prefrontal cortex of alcohol-preferring rats compared to Wistar rats. Alcohol 2006 1.01
29 Effects of serotonin-3 receptor antagonists on the intracranial self-administration of ethanol within the ventral tegmental area of Wistar rats. Psychopharmacology (Berl) 2002 1.00
30 In vivo time-course changes in ethanol levels sampled with subcutaneous microdialysis. Alcohol Clin Exp Res 2008 0.98
31 Effects of multiple alcohol deprivations on operant ethanol self-administration by high-alcohol-drinking replicate rat lines. Alcohol 2006 0.98
32 Serotonin-3 receptors in the actions of alcohol, alcohol reinforcement, and alcoholism. Alcohol Clin Exp Res 2004 0.98
33 Effects of concurrent access to a single concentration or multiple concentrations of ethanol on the intake of ethanol by male and female periadolescent alcohol-preferring (P) rats. Alcohol 2003 0.98
34 Effects of concurrent access to multiple ethanol concentrations and repeated deprivations on alcohol intake of high-alcohol-drinking (HAD) rats. Addict Biol 2008 0.97
35 Effects of short deprivation and re-exposure intervals on the ethanol drinking behavior of selectively bred high alcohol-consuming rats. Alcohol 2008 0.96
36 Point mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- mice. Blood 2008 0.95
37 Alcohol stimulates the release of dopamine in the ventral pallidum but not in the globus pallidus: a dual-probe microdialysis study. Neuropsychopharmacology 2003 0.95
38 Determination of the Plk4/Sak consensus phosphorylation motif using peptide spots arrays. FEBS Lett 2006 0.95
39 Sensitized effects of neuropeptide Y on multiple ingestive behaviors in P rats following ethanol abstinence. Pharmacol Biochem Behav 2005 0.92
40 Effects of long-term episodic access to ethanol on the expression of an alcohol deprivation effect in low alcohol-consuming rats. Alcohol Clin Exp Res 2004 0.92
41 Chronic ethanol consumption increases dopamine uptake in the nucleus accumbens of high alcohol drinking rats. Alcohol 2006 0.91
42 Serotonin-3 receptors in the posterior ventral tegmental area regulate ethanol self-administration of alcohol-preferring (P) rats. Alcohol 2010 0.91
43 Epigenetic regulator Smchd1 functions as a tumor suppressor. Cancer Res 2012 0.90
44 Rapid identification of linear protein domain binding motifs using peptide SPOT arrays. Methods Mol Biol 2009 0.90
45 Involvement of the mesopallidal dopamine system in ethanol reinforcement. Alcohol 2004 0.89
46 Dawn of the dead: protein pseudokinases signal new adventures in cell biology. Biochem Soc Trans 2013 0.89
47 Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor. FEBS J 2013 0.89
48 Ethanol drinking experience attenuates (-)sulpiride-induced increases in extracellular dopamine levels in the nucleus accumbens of alcohol-preferring (P) rats. Alcohol Clin Exp Res 2003 0.88
49 In vitro JAK kinase activity and inhibition assays. Methods Mol Biol 2013 0.88
50 The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis. J Clin Invest 2016 0.86
51 Techniques to examine nucleotide binding by pseudokinases. Biochem Soc Trans 2013 0.85
52 Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1. PLoS One 2013 0.85
53 Regulation of Janus kinases by SOCS proteins. Biochem Soc Trans 2013 0.85
54 A single, moderate ethanol exposure alters extracellular dopamine levels and dopamine d receptor function in the nucleus accumbens of wistar rats. Alcohol Clin Exp Res 2009 0.84
55 An efficient high-throughput screening method for MYST family acetyltransferases, a new class of epigenetic drug targets. J Biomol Screen 2011 0.84
56 A new isoform of interleukin-3 receptor {alpha} with novel differentiation activity and high affinity binding mode. J Biol Chem 2008 0.83
57 Mechanistic insights into activation and SOCS3-mediated inhibition of myeloproliferative neoplasm-associated JAK2 mutants from biochemical and structural analyses. Biochem J 2014 0.83
58 Characterization of kinase target phosphorylation consensus motifs using peptide SPOT arrays. Methods Mol Biol 2009 0.82
59 Effects of alcohol and saccharin deprivations on concurrent ethanol and saccharin operant self-administration by alcohol-preferring (P) rats. Alcohol 2008 0.82
60 Exchange enhanced sensitivity gain for solvent-exchangeable protons in 2D 1H-15N heteronuclear correlation spectra acquired with band-selective pulses. J Magn Reson 2011 0.82
61 High yield production of a soluble human interleukin-3 variant from E. coli with wild-type bioactivity and improved radiolabeling properties. PLoS One 2013 0.81
62 Heart rate and motor-activating effects of orally self-administered ethanol in alcohol-preferring (P) rats. Alcohol Clin Exp Res 2002 0.81
63 The Ig-like domain of human GM-CSF receptor alpha plays a critical role in cytokine binding and receptor activation. Biochem J 2010 0.80
64 Murine interleukin-3: structure, dynamics, and conformational heterogeneity in solution. Biochemistry 2011 0.80
65 Dopamine receptor regulation of ethanol intake and extracellular dopamine levels in the ventral pallidum of alcohol preferring (P) rats. Drug Alcohol Depend 2005 0.80
66 Functional characterization of c-Mpl ectodomain mutations that underlie congenital amegakaryocytic thrombocytopenia. Growth Factors 2014 0.79
67 Local cerebral glucose utilization after relapse in ethanol drinking in alcohol-preferring (P) rats. Alcohol 2002 0.79
68 1H, 13C and 15N resonance assignments of a highly-soluble murine interleukin-3 analogue with wild-type bioactivity. Biomol NMR Assign 2010 0.78
69 Effect of housing conditions on sulpiride-induced increases in extracellular dopamine (DA) levels in the nucleus accumbens of alcohol-preferring (P) rats. Brain Res 2004 0.78
70 Sedative and motor-impairing effects of neuropeptide Y and ethanol in selectively bred P and NP rats. Pharmacol Biochem Behav 2004 0.77
71 Crystal structure of the mouse interleukin-3 β-receptor: insights into interleukin-3 binding and receptor activation. Biochem J 2014 0.76
72 Autonomic activation associated with ethanol self-administration in adult female P rats. Pharmacol Biochem Behav 2008 0.76
73 Two modes of beta-receptor recognition are mediated by distinct epitopes on mouse and human interleukin-3. J Biol Chem 2010 0.76
74 The role of interchain heterodisulfide formation in activation of the human common beta and mouse betaIL-3 receptors. J Biol Chem 2010 0.76
75 Erratum: EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation. Nat Microbiol 2017 0.75
76 Use of bilobed partial resuscitative endovascular balloon occlusion of the aorta is logistically superior in prolonged management of a highly lethal aortic injury. J Trauma Acute Care Surg 2020 0.75
77 Increased radiodensity of the proximal pole of the scaphoid: a common finding in computed tomography imaging of the wrist. J Comput Assist Tomogr 2006 0.75